LOCUS       NM_133994               1873 bp    mRNA    linear   ROD 29-JUL-2024
DEFINITION  Mus musculus glutathione S-transferase, theta 3 (Gstt3), transcript
            variant 1, mRNA.
ACCESSION   NM_133994
VERSION     NM_133994.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1873)
  AUTHORS   Jones,M.R., Dilai,S., Lingampally,A., Chao,C.M., Danopoulos,S.,
            Carraro,G., Mukhametshina,R., Wilhelm,J., Baumgart-Vogt,E., Al
            Alam,D., Chen,C., Minoo,P., Zhang,J.S. and Bellusci,S.
  TITLE     A Comprehensive Analysis of Fibroblast Growth Factor Receptor 2b
            Signaling on Epithelial Tip Progenitor Cells During Early Mouse
            Lung Branching Morphogenesis
  JOURNAL   Front Genet 9, 746 (2019)
   PUBMED   30728831
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1873)
  AUTHORS   Endoh-Yamagami,S., Karkar,K.M., May,S.R., Cobos,I., Thwin,M.T.,
            Long,J.E., Ashique,A.M., Zarbalis,K., Rubenstein,J.L. and
            Peterson,A.S.
  TITLE     A mutation in the pericentrin gene causes abnormal interneuron
            migration to the olfactory bulb in mice
  JOURNAL   Dev Biol 340 (1), 41-53 (2010)
   PUBMED   20096683
REFERENCE   3  (bases 1 to 1873)
  AUTHORS   Coggan,M., Flanagan,J.U., Parker,M.W., Vichai,V., Pearson,W.R. and
            Board,P.G.
  TITLE     Identification and characterization of GSTT3, a third murine Theta
            class glutathione transferase
  JOURNAL   Biochem J 366 (Pt 1), 323-332 (2002)
   PUBMED   12038961
  REMARK    GeneRIF: Identification and characterization of GSTT3 [GSTT3]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC142499.9.
            
            On Mar 21, 2007 this sequence version replaced NM_133994.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF508157.1, BC057964.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849386, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-568               AC142499.9         142804-143371
            569-656             AC142499.9         146030-146117
            657-807             AC142499.9         147324-147474
            808-984             AC142499.9         148171-148347
            985-1873            AC142499.9         149208-150096
FEATURES             Location/Qualifiers
     source          1..1873
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 38.58 cM"
     gene            1..1873
                     /gene="Gstt3"
                     /note="glutathione S-transferase, theta 3"
                     /db_xref="GeneID:103140"
                     /db_xref="MGI:MGI:2143526"
     exon            1..568
                     /gene="Gstt3"
                     /inference="alignment:Splign:2.1.0"
     CDS             457..1182
                     /gene="Gstt3"
                     /EC_number="2.5.1.18"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="glutathione S-transferase theta-3 isoform 1"
                     /protein_id="NP_598755.1"
                     /db_xref="CCDS:CCDS23931.1"
                     /db_xref="GeneID:103140"
                     /db_xref="MGI:MGI:2143526"
                     /translation="MGLELYLDLMSQPCRAVYIFAKKNGIPFQLRTIELLKGQQYTDS
                     FAQVNPLRKVPALKDGDFVLAESVAILLYLSRKYKAPDHWYPQDLQTRARVDEYLAWQ
                     HTALRSCCTRAMWQKMMFPVFLGQPVPPEMLASTLAELDGCLQVLEDKFLRNQAFLTG
                     SHISVADLVAITELMHPVSAGCKIFESRPKLAAWRQRVEAEVGESLFQEAHEVVLKAK
                     DMPPLMDPALKEKLKLSVQCLLH"
     exon            569..656
                     /gene="Gstt3"
                     /inference="alignment:Splign:2.1.0"
     exon            657..807
                     /gene="Gstt3"
                     /inference="alignment:Splign:2.1.0"
     exon            808..984
                     /gene="Gstt3"
                     /inference="alignment:Splign:2.1.0"
     exon            985..1873
                     /gene="Gstt3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gatctccgaa gccactcctc cctcaacctt ttttgtgagt ggagggaaag aaagtgaatt
       61 tgagggcagt tagcacggct aatctgcccc taaattcacc aatagagacg ccggttgtgt
      121 cagtttttcc tttactgggt tccgttcctc atttggctga agcacggagg tacaggggcc
      181 agtttggctc caaaccaaga ctcgggctca tagttcaggt tcatctgttt cgggggttaa
      241 cttgcagtcc ggcactgatt ggcccaaagt tcttgtggtc atccaatggg aaggaagatt
      301 gggatcgagc tccgatcgag gctaagaggc acttgaggag ctgggaccca gccgttcctg
      361 ctcgccgttg cggctgctcc ggcttctgtc cccagaggca gttcacccga ggctagttcc
      421 cgaggtctgc cagcggctac tcccacagcc tccgccatgg gtctggagct ctacctggac
      481 ctgatgtccc aaccctgccg tgctgtctac atcttcgcca agaagaacgg catccccttc
      541 cagctgcgta ccatagagct gcttaaaggt cagcagtaca cagattcctt cgcccaggtg
      601 aaccctttga ggaaggtgcc agctttgaag gatggggact tcgtcttggc agagagtgtg
      661 gccatcttgt tgtatctgag tagaaagtac aaggcccccg accactggta ccctcaggat
      721 ctgcagactc gagctcgtgt agacgagtac ctggcatggc agcacacagc cctgcggagt
      781 tgttgcacca gggccatgtg gcagaagatg atgttccctg tgttcctggg acagcccgta
      841 cctcctgaga tgctggcatc caccttggct gaactggatg ggtgcctgca ggtgctagag
      901 gacaagttcc tgcggaacca ggccttcctt acaggatccc atatttctgt ggctgacttg
      961 gtggccatca cagagctgat gcatcctgtc agtgctggct gcaaaatctt tgagagccga
     1021 cccaaactgg ctgcctggcg tcagagagta gaagccgaag tgggggagag cctcttccag
     1081 gaggcccatg aagttgtcct gaaggccaag gatatgcctc ccttgatgga ccctgccttg
     1141 aaagagaagc tgaagctctc tgtgcagtgt ttgttacact gagggaatag ctcgaactgg
     1201 gagacagacg gtcaagggaa actcggggcc gtgcaagcga agagatgagg ctgtctggct
     1261 ctttggctgt cactaggaca tagggtctct ggtccgcaat ttcctctctg catcacctgt
     1321 gttccctctg tgtccccacc tggcttgtgc tgtaacatca gttcttatct gacttctgga
     1381 gagagctcca ggaaaatact tgggagaaac gtatctggcc atattccttt tctttgaaac
     1441 tttacaaacc attgaacctt cccccatcct ccaagccata tttgtatata catgtatata
     1501 cacatataca tataattgat atctggtacc acgtgaccct ctgtgctcct caaccctggt
     1561 gcctcccttc ctcagttttg gcatgcagga tctatgatct ctcagttgaa tacatgcaag
     1621 agacggggat tgactagtga aagacctttg tcctctgcgt ctttgcttcc tgccataggt
     1681 ggggtgcagg gctggttcct ttgtgggagt ggaagttgct tggtatgtcc tgactttcca
     1741 aattcttgtc ccaagcattc taaccctgac tgctgccttc tacctgtctc cggctccaaa
     1801 ctgtcaagct acttaatctt gtgccataag acgtctttta tgtgccttac ctaataaata
     1861 cattgttaac aga
//
