LOCUS       NM_181796                785 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus glutathione S-transferase, pi 2 (Gstp2), mRNA.
ACCESSION   NM_181796
VERSION     NM_181796.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 785)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 785)
  AUTHORS   van de Wetering,C., Manuel,A.M., Sharafi,M., Aboushousha,R.,
            Qian,X., Erickson,C., MacPherson,M., Chan,G., Adcock,I.M.,
            ZounematKermani,N., Schleich,F., Louis,R., Bohrnsen,E.,
            D'Alessandro,A., Wouters,E.F., Reynaert,N.L., Li,J., Wolf,C.R.,
            Henderson,C.J., Lundblad,L.K.A., Poynter,M.E., Dixon,A.E.,
            Irvin,C.G., van der Vliet,A., van der Velden,J.L. and
            Janssen-Heininger,Y.M.
  TITLE     Glutathione-S-transferase P promotes glycolysis in asthma in
            association with oxidation of pyruvate kinase M2
  JOURNAL   Redox Biol 47, 102160 (2021)
   PUBMED   34624602
REFERENCE   3  (bases 1 to 785)
  AUTHORS   Liu,X., Blazejewski,S.M., Bennison,S.A. and Toyo-Oka,K.
  TITLE     Glutathione S-transferase Pi (Gstp) proteins regulate
            neuritogenesis in the developing cerebral cortex
  JOURNAL   Hum Mol Genet 30 (1), 30-45 (2021)
   PUBMED   33437989
  REMARK    GeneRIF: Glutathione S-transferase Pi (Gstp) proteins regulate
            neuritogenesis in the developing cerebral cortex.
REFERENCE   4  (bases 1 to 785)
  AUTHORS   Niitsu,Y., Sato,Y., Takanashi,K., Hayashi,T., Kubo-Birukawa,N.,
            Shimizu,F., Fujitani,N., Shimoyama,R., Kukitsu,T., Kurata,W.,
            Tashiro,Y. and Listowsky,I.
  TITLE     A CRAF/glutathione-S-transferase P1 complex sustains autocrine
            growth of cancers with KRAS and BRAF mutations
  JOURNAL   Proc Natl Acad Sci U S A 117 (32), 19435-19445 (2020)
   PUBMED   32719131
REFERENCE   5  (bases 1 to 785)
  AUTHORS   Jin,L., Jagatheesan,G., Lynch,J., Guo,L. and Conklin,D.J.
  TITLE     Crotonaldehyde-induced vascular relaxation and toxicity: Role of
            endothelium and transient receptor potential ankyrin-1 (TRPA1)
  JOURNAL   Toxicol Appl Pharmacol 398, 115012 (2020)
   PUBMED   32320793
  REMARK    Erratum:[Toxicol Appl Pharmacol. 2020 Aug 15;401:115114. doi:
            10.1016/j.taap.2020.115114.. PMID: 32598891]
REFERENCE   6  (bases 1 to 785)
  AUTHORS   Xu,X. and Stambrook,P.J.
  TITLE     Two murine GSTpi genes are arranged in tandem and are
            differentially expressed
  JOURNAL   J Biol Chem 269 (48), 30268-30273 (1994)
   PUBMED   7982937
REFERENCE   7  (bases 1 to 785)
  AUTHORS   Rochelle,J.M., Watson,M.L., Oakey,R.J. and Seldin,M.F.
  TITLE     A linkage map of mouse chromosome 19: definition of comparative
            mapping relationships with human chromosomes 10 and 11 including
            the MEN1 locus
  JOURNAL   Genomics 14 (1), 26-31 (1992)
   PUBMED   1358795
REFERENCE   8  (bases 1 to 785)
  AUTHORS   Miles,J.S., Moss,J.E., Taylor,B.A., Burchell,B. and Wolf,C.R.
  TITLE     Mapping genes encoding drug-metabolizing enzymes in recombinant
            inbred mice
  JOURNAL   Genomics 11 (2), 309-316 (1991)
   PUBMED   1685137
REFERENCE   9  (bases 1 to 785)
  AUTHORS   Board,P.G., Webb,G.C. and Coggan,M.
  TITLE     Isolation of a cDNA clone and localization of the human glutathione
            S-transferase 3 genes to chromosome bands 11q13 and 12q13-14
  JOURNAL   Ann Hum Genet 53 (3), 205-213 (1989)
   PUBMED   2596826
REFERENCE   10 (bases 1 to 785)
  AUTHORS   Morrow,C.S., Cowan,K.H. and Goldsmith,M.E.
  TITLE     Structure of the human genomic glutathione S-transferase-pi gene
  JOURNAL   Gene 75 (1), 3-11 (1989)
   PUBMED   2542132
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC064781.1.
            
            On Mar 20, 2004 this sequence version replaced NM_181796.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC064781.1, BC094623.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..785
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 3.75 cM"
     gene            1..785
                     /gene="Gstp2"
                     /gene_synonym="Gst-3; Gst3; GSTpiA"
                     /note="glutathione S-transferase, pi 2"
                     /db_xref="GeneID:14869"
                     /db_xref="MGI:MGI:95864"
     exon            1..57
                     /gene="Gstp2"
                     /gene_synonym="Gst-3; Gst3; GSTpiA"
                     /inference="alignment:Splign:2.1.0"
     CDS             57..689
                     /gene="Gstp2"
                     /gene_synonym="Gst-3; Gst3; GSTpiA"
                     /EC_number="2.5.1.18"
                     /note="gst P2; GST-piA; GST YF-YF; GST class-pi; Gst p-2"
                     /codon_start=1
                     /product="glutathione S-transferase P 2"
                     /protein_id="NP_861461.1"
                     /db_xref="CCDS:CCDS29412.1"
                     /db_xref="GeneID:14869"
                     /db_xref="MGI:MGI:95864"
                     /translation="MPPYTIVYFPSPGRCEAMRMLLADQGQSWKEEVVTIDTWMQGLL
                     KPTCLYGQLPKFEDGDLTLYQSNAILRHLGRSLGLYGKNQREAAQVDMVNDGVEDLRG
                     KYGTMIYRNYENGKNDYVKALPGHLKPFETLLSQNQGGKAFIVGDQISFADYNLLDLL
                     LIHQVLAPGCLDNFPLLSAYVARLSARPKIKAFLSSPEHVNRPINGNGKQ"
     exon            58..93
                     /gene="Gstp2"
                     /gene_synonym="Gst-3; Gst3; GSTpiA"
                     /inference="alignment:Splign:2.1.0"
     exon            94..200
                     /gene="Gstp2"
                     /gene_synonym="Gst-3; Gst3; GSTpiA"
                     /inference="alignment:Splign:2.1.0"
     exon            201..288
                     /gene="Gstp2"
                     /gene_synonym="Gst-3; Gst3; GSTpiA"
                     /inference="alignment:Splign:2.1.0"
     exon            289..392
                     /gene="Gstp2"
                     /gene_synonym="Gst-3; Gst3; GSTpiA"
                     /inference="alignment:Splign:2.1.0"
     exon            393..500
                     /gene="Gstp2"
                     /gene_synonym="Gst-3; Gst3; GSTpiA"
                     /inference="alignment:Splign:2.1.0"
     exon            501..752
                     /gene="Gstp2"
                     /gene_synonym="Gst-3; Gst3; GSTpiA"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagacacctc tctgactatt cagcacttga tccccacttc tctctgcaca gcagccatgc
       61 cgccgtacac cattgtctac ttcccaagtc cagggcggtg tgaggccatg cgcatgctgc
      121 tggctgacca gggccagagc tggaaggagg aggtggttac catagatacc tggatgcaag
      181 gcttgctcaa gcccacttgt ctgtatgggc agctccccaa gtttgaggat ggagacctca
      241 ccctttacca atctaatgcc atcttgagac accttggccg ctctttgggg ctttatggga
      301 aaaaccagag ggaggccgcc caggtggata tggtgaatga tggggtggag gaccttcgcg
      361 gcaaatatgg caccatgatc tacagaaact atgagaatgg taagaatgac tacgtgaagg
      421 ccctgcctgg gcatctgaag ccttttgaga ccctgctgtc ccagaaccag ggaggcaaag
      481 ctttcatcgt gggtgaccag atctcctttg ccgattacaa cttgctggac ctgctgctga
      541 tccaccaagt cctggcccct ggctgcctgg acaacttccc cctgctctct gcctatgtgg
      601 ctcgcctcag tgcccggccc aagatcaagg cctttctgtc ctccccggaa catgtgaacc
      661 gtcccatcaa tggcaatggc aaacagtagt ggactgaaga gacaagagct tcttgtcccc
      721 gttttcccag cactaataaa gtttgtaaga caaaaaaaaa aaaaaaaaaa aaaaaaaaaa
      781 aaaaa
//
