LOCUS       NM_013541                744 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus glutathione S-transferase, pi 1 (Gstp1), mRNA.
ACCESSION   NM_013541
VERSION     NM_013541.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 744)
  AUTHORS   Sun,X., Guo,C., Huang,C., Lv,N., Chen,H., Huang,H., Zhao,Y.,
            Sun,S., Zhao,D., Tian,J., Chen,X. and Zhang,Y.
  TITLE     GSTP alleviates acute lung injury by S-glutathionylation of KEAP1
            and subsequent activation of NRF2 pathway
  JOURNAL   Redox Biol 71, 103116 (2024)
   PUBMED   38479222
  REMARK    GeneRIF: GSTP alleviates acute lung injury by S-glutathionylation
            of KEAP1 and subsequent activation of NRF2 pathway.
REFERENCE   2  (bases 1 to 744)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 744)
  AUTHORS   Wei,C., Shi,M., Dong,S., Li,Z., Zhao,B., Liu,D., Li,G., Cen,J.,
            Yu,L., Liang,X. and Shi,L.
  TITLE     SIRT5-related lysine demalonylation of GSTP1 contributes to
            cardiomyocyte pyroptosis suppression in diabetic cardiomyopathy
  JOURNAL   Int J Biol Sci 20 (2), 585-605 (2024)
   PUBMED   38169591
  REMARK    GeneRIF: SIRT5-related lysine demalonylation of GSTP1 contributes
            to cardiomyocyte pyroptosis suppression in diabetic cardiomyopathy.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 744)
  AUTHORS   Lettieri,A., Oleari,R., van den Munkhof,M.H., van Battum,E.Y.,
            Verhagen,M.G., Tacconi,C., Spreafico,M., Paganoni,A.J.J.,
            Azzarelli,R., Andre',V., Amoruso,F., Palazzolo,L., Eberini,I.,
            Dunkel,L., Howard,S.R., Fantin,A., Pasterkamp,R.J. and Cariboni,A.
  TITLE     SEMA6A drives GnRH neuron-dependent puberty onset by tuning median
            eminence vascular permeability
  JOURNAL   Nat Commun 14 (1), 8097 (2023)
   PUBMED   38062045
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 744)
  AUTHORS   Bejarano,E., Whitcomb,E.A., Pfeiffer,R.L., Rose,K.L., Asensio,M.J.,
            Rodriguez-Navarro,J.A., Ponce-Mora,A., Canto,A., Almansa,I.,
            Schey,K.L., Jones,B.W., Taylor,A. and Rowan,S.
  TITLE     Unbalanced redox status network as an early pathological event in
            congenital cataracts
  JOURNAL   Redox Biol 66, 102869 (2023)
   PUBMED   37677999
REFERENCE   6  (bases 1 to 744)
  AUTHORS   Beiswanger,C.M., Diegmann,M.H., Novak,R.F., Philbert,M.A.,
            Graessle,T.L., Reuhl,K.R. and Lowndes,H.E.
  TITLE     Developmental changes in the cellular distribution of glutathione
            and glutathione S-transferases in the murine nervous system
  JOURNAL   Neurotoxicology 16 (3), 425-440 (1995)
   PUBMED   8584275
REFERENCE   7  (bases 1 to 744)
  AUTHORS   Xu,X. and Stambrook,P.J.
  TITLE     Two murine GSTpi genes are arranged in tandem and are
            differentially expressed
  JOURNAL   J Biol Chem 269 (48), 30268-30273 (1994)
   PUBMED   7982937
REFERENCE   8  (bases 1 to 744)
  AUTHORS   Garcia-Saez,I., Parraga,A., Phillips,M.F., Mantle,T.J. and Coll,M.
  TITLE     Molecular structure at 1.8 A of mouse liver class pi glutathione
            S-transferase complexed with S-(p-nitrobenzyl)glutathione and other
            inhibitors
  JOURNAL   J Mol Biol 237 (3), 298-314 (1994)
   PUBMED   8145243
REFERENCE   9  (bases 1 to 744)
  AUTHORS   Bammler,T.K., Smith,C.A. and Wolf,C.R.
  TITLE     Isolation and characterization of two mouse Pi-class glutathione
            S-transferase genes
  JOURNAL   Biochem J 298 (Pt 2) (Pt 2), 385-390 (1994)
   PUBMED   8135745
REFERENCE   10 (bases 1 to 744)
  AUTHORS   Hatayama,I., Satoh,K. and Sato,K.
  TITLE     A cDNA sequence coding a class pi glutathione S-transferase of
            mouse
  JOURNAL   Nucleic Acids Res 18 (15), 4606 (1990)
   PUBMED   2388840
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            D30687.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: D30687.1, BC061109.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..744
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 3.75 cM"
     gene            1..744
                     /gene="Gstp1"
                     /gene_synonym="GstpiB"
                     /note="glutathione S-transferase, pi 1"
                     /db_xref="GeneID:14870"
                     /db_xref="MGI:MGI:95865"
     exon            1..50
                     /gene="Gstp1"
                     /gene_synonym="GstpiB"
                     /inference="alignment:Splign:2.1.0"
     CDS             50..682
                     /gene="Gstp1"
                     /gene_synonym="GstpiB"
                     /EC_number="2.5.1.18"
                     /note="gst P1; GST-piB; GST YF-YF; GST class-pi;
                     preadipocyte growth factor; Gst p-1"
                     /codon_start=1
                     /product="glutathione S-transferase P 1"
                     /protein_id="NP_038569.1"
                     /db_xref="CCDS:CCDS29411.1"
                     /db_xref="GeneID:14870"
                     /db_xref="MGI:MGI:95865"
                     /translation="MPPYTIVYFPVRGRCEAMRMLLADQGQSWKEEVVTIDTWMQGLL
                     KPTCLYGQLPKFEDGDLTLYQSNAILRHLGRSLGLYGKNQREAAQMDMVNDGVEDLRG
                     KYVTLIYTNYENGKNDYVKALPGHLKPFETLLSQNQGGKAFIVGDQISFADYNLLDLL
                     LIHQVLAPGCLDNFPLLSAYVARLSARPKIKAFLSSPEHVNRPINGNGKQ"
     exon            51..86
                     /gene="Gstp1"
                     /gene_synonym="GstpiB"
                     /inference="alignment:Splign:2.1.0"
     exon            87..193
                     /gene="Gstp1"
                     /gene_synonym="GstpiB"
                     /inference="alignment:Splign:2.1.0"
     exon            194..281
                     /gene="Gstp1"
                     /gene_synonym="GstpiB"
                     /inference="alignment:Splign:2.1.0"
     exon            282..385
                     /gene="Gstp1"
                     /gene_synonym="GstpiB"
                     /inference="alignment:Splign:2.1.0"
     exon            386..493
                     /gene="Gstp1"
                     /gene_synonym="GstpiB"
                     /inference="alignment:Splign:2.1.0"
     exon            494..744
                     /gene="Gstp1"
                     /gene_synonym="GstpiB"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctctgagtac ccctctgtct acgcagcact gaatccgcac ccagcaggca tgccaccata
       61 caccattgtc tacttcccag ttcgagggcg gtgtgaggcc atgcgaatgc tgctggctga
      121 ccagggccag agctggaagg aggaggtggt taccatagat acctggatgc aaggcttgct
      181 caagcccact tgtctgtatg ggcagctccc caagtttgag gatggagacc tcacccttta
      241 ccaatctaat gccatcttga gacaccttgg ccgctctttg gggctttatg ggaaaaacca
      301 gagggaggcc gcccagatgg atatggtgaa tgatggggtg gaggaccttc gcggcaaata
      361 tgtcaccctc atctacacca actatgagaa tggtaagaat gactacgtga aggccctgcc
      421 tgggcatctg aagccttttg agaccctgct gtcccagaac cagggaggca aagctttcat
      481 cgtgggtgac cagatctcct ttgccgatta caacttgctg gacctgctgc tgatccacca
      541 agtcctggcc cctggctgcc tggacaactt ccccctgctc tctgcctatg tggctcgcct
      601 cagtgcccgg cccaagatca aggcctttct gtcctccccg gaacatgtga accgtcccat
      661 caatggcaat ggcaaacagt agtggactga agagacaaga gcttcttgtc cccgttttcc
      721 cagcactaat aaagtttgta agac
//
