LOCUS       NM_029555                930 bp    mRNA    linear   ROD 06-APR-2024
DEFINITION  Mus musculus glutathione S-transferase kappa 1 (Gstk1), mRNA.
ACCESSION   NM_029555
VERSION     NM_029555.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 930)
  AUTHORS   Liu,Y., Chen,W., Li,C., Li,L., Yang,M., Jiang,N., Luo,S., Xi,Y.,
            Liu,C., Han,Y., Zhao,H., Zhu,X., Yuan,S., Xiao,L. and Sun,L.
  TITLE     DsbA-L interacting with catalase in peroxisome improves tubular
            oxidative damage in diabetic nephropathy
  JOURNAL   Redox Biol 66, 102855 (2023)
   PUBMED   37597421
  REMARK    GeneRIF: DsbA-L interacting with catalase in peroxisome improves
            tubular oxidative damage in diabetic nephropathy.
REFERENCE   2  (bases 1 to 930)
  AUTHORS   Cui,P., Chen,C., Cui,Y., Qiu,X., Yue,K., Li,T., Zhang,H., Yuan,W.,
            Xie,Y., Guo,Y., Tang,Z., Li,Y., Peng,F., Jiang,X., Luo,X., Peng,L.,
            Qi,Z. and Dai,H.
  TITLE     DsbA-L deletion attenuates LPS-induced acute kidney injury by
            modulating macrophage polarization
  JOURNAL   Eur J Immunol 53 (10), e2250071 (2023)
   PUBMED   37379419
  REMARK    GeneRIF: DsbA-L deletion attenuates LPS-induced acute kidney injury
            by modulating macrophage polarization.
REFERENCE   3  (bases 1 to 930)
  AUTHORS   Yang,M., Zhang,Q., Luo,S., Han,Y., Zhao,H., Jiang,N., Liu,Y.,
            Li,L., Li,C., Liu,C., He,L., Zhu,X., Liu,Y. and Sun,L.
  TITLE     DsbA-L alleviates tubular injury in diabetic nephropathy by
            activating mitophagy through maintenance of MAM integrity
  JOURNAL   Clin Sci (Lond) 137 (12), 931-945 (2023)
   PUBMED   37226722
  REMARK    GeneRIF: DsbA-L alleviates tubular injury in diabetic nephropathy
            by activating mitophagy through maintenance of MAM integrity.
REFERENCE   4  (bases 1 to 930)
  AUTHORS   Li,X., Pan,J., Li,H., Li,G., Liu,B., Tang,X., Liu,X., He,Z.,
            Peng,Z., Zhang,H., Wang,L., Li,Y., Xiang,X., Chai,X., Yuan,Y.,
            Zheng,P. and Zhang,D.
  TITLE     DsbA-L interacts with VDAC1 in mitochondrion-mediated tubular cell
            apoptosis and contributes to the progression of acute kidney
            disease
  JOURNAL   EBioMedicine 76, 103859 (2022)
   PUBMED   35124430
REFERENCE   5  (bases 1 to 930)
  AUTHORS   Yang,M., Luo,S., Jiang,N., Wang,X., Han,Y., Zhao,H., Xiong,X.,
            Liu,Y., Zhao,C., Zhu,X. and Sun,L.
  TITLE     DsbA-L Ameliorates Renal Injury Through the AMPK/NLRP3 Inflammasome
            Signaling Pathway in Diabetic Nephropathy
  JOURNAL   Front Physiol 12, 659751 (2021)
   PUBMED   33995126
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 930)
  AUTHORS   Thomson,R.E., Bigley,A.L., Foster,J.R., Jowsey,I.R., Elcombe,C.R.,
            Orton,T.C. and Hayes,J.D.
  TITLE     Tissue-specific expression and subcellular distribution of murine
            glutathione S-transferase class kappa
  JOURNAL   J Histochem Cytochem 52 (5), 653-662 (2004)
   PUBMED   15100242
REFERENCE   7  (bases 1 to 930)
  AUTHORS   Osawa,M., Horiuchi,H., Tian,W. and Kaneko,M.
  TITLE     Divergent evolution of the prolactin-inducible protein gene and
            related genes in the mouse genome
  JOURNAL   Gene 325, 179-186 (2004)
   PUBMED   14697523
REFERENCE   8  (bases 1 to 930)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   9  (bases 1 to 930)
  AUTHORS   Da Cruz,S., Xenarios,I., Langridge,J., Vilbois,F., Parone,P.A. and
            Martinou,J.C.
  TITLE     Proteomic analysis of the mouse liver mitochondrial inner membrane
  JOURNAL   J Biol Chem 278 (42), 41566-41571 (2003)
   PUBMED   12865426
REFERENCE   10 (bases 1 to 930)
  AUTHORS   Jowsey,I.R., Thomson,R.E., Orton,T.C., Elcombe,C.R. and Hayes,J.D.
  TITLE     Biochemical and genetic characterization of a murine class Kappa
            glutathione S-transferase
  JOURNAL   Biochem J 373 (Pt 2), 559-569 (2003)
   PUBMED   12720545
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC155654.16.
            
            On Nov 17, 2006 this sequence version replaced NM_029555.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK002661.1, BC038151.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-159               AC155654.16        134240-134398
            160-241             AC155654.16        134855-134936
            242-370             AC155654.16        135116-135244
            371-471             AC155654.16        135789-135889
            472-507             AC155654.16        136039-136074
            508-624             AC155654.16        137684-137800
            625-718             AC155654.16        138144-138237
            719-930             AC155654.16        138535-138746
FEATURES             Location/Qualifiers
     source          1..930
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 20.52 cM"
     gene            1..930
                     /gene="Gstk1"
                     /gene_synonym="0610025I19Rik; DsbA-L"
                     /note="glutathione S-transferase kappa 1"
                     /db_xref="GeneID:76263"
                     /db_xref="MGI:MGI:1923513"
     exon            1..159
                     /gene="Gstk1"
                     /gene_synonym="0610025I19Rik; DsbA-L"
                     /inference="alignment:Splign:2.1.0"
     CDS             88..768
                     /gene="Gstk1"
                     /gene_synonym="0610025I19Rik; DsbA-L"
                     /EC_number="2.5.1.18"
                     /note="glutathione S-transferase class kappa; mGSTK1;
                     GSTK1-1; GST 13-13; GST class-kappa; glutathione
                     S-transferase subunit 13"
                     /codon_start=1
                     /product="glutathione S-transferase kappa 1"
                     /protein_id="NP_083831.1"
                     /db_xref="CCDS:CCDS20063.1"
                     /db_xref="GeneID:76263"
                     /db_xref="MGI:MGI:1923513"
                     /translation="MGPAPRILELFYDVLSPYSWLGFEVLCRYQHLWNIKLQLRPTLI
                     AGIMKDSGNQPPAMVPRKGQYIFKEIPLLKQFFQVPLNIPKDFFGETVKKGSINAMRF
                     LTTVSMEQPEMLEKVSREIWMRVWSRDEDITEYQSILAAAVKAGMSTAQAQHFLEKIS
                     TQQVKNKLIENTDAACKYGAFGLPTTVAHVDGKTYMLFGSDRLELLAYLLGEKWMGPV
                     PPTANARL"
     exon            160..241
                     /gene="Gstk1"
                     /gene_synonym="0610025I19Rik; DsbA-L"
                     /inference="alignment:Splign:2.1.0"
     exon            242..370
                     /gene="Gstk1"
                     /gene_synonym="0610025I19Rik; DsbA-L"
                     /inference="alignment:Splign:2.1.0"
     exon            371..471
                     /gene="Gstk1"
                     /gene_synonym="0610025I19Rik; DsbA-L"
                     /inference="alignment:Splign:2.1.0"
     exon            472..507
                     /gene="Gstk1"
                     /gene_synonym="0610025I19Rik; DsbA-L"
                     /inference="alignment:Splign:2.1.0"
     exon            508..624
                     /gene="Gstk1"
                     /gene_synonym="0610025I19Rik; DsbA-L"
                     /inference="alignment:Splign:2.1.0"
     exon            625..718
                     /gene="Gstk1"
                     /gene_synonym="0610025I19Rik; DsbA-L"
                     /inference="alignment:Splign:2.1.0"
     exon            719..930
                     /gene="Gstk1"
                     /gene_synonym="0610025I19Rik; DsbA-L"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggactacgat tggctgcttg ctcttcagct acctaaagct cttcggcagc ccaaggcttc
       61 aagttcactt tctctcacca ctgtagaatg gggccggcgc cgcgcatcct ggaactcttc
      121 tacgacgtgc tgtccccgta ctcctggctg ggctttgagg tcctatgcag ataccaacac
      181 ctctggaata taaagctgca gttgcggccc actttaatcg ctgggatcat gaaagacagc
      241 ggaaaccaac cacctgctat ggttccccga aaaggccagt acatcttcaa agagattcct
      301 ctcctgaagc agttcttcca ggttcccctc aacataccca aggatttctt tggtgagact
      361 gtgaagaaag gaagtataaa tgccatgcgc ttcctcacca ctgtaagcat ggagcaacca
      421 gagatgctgg agaaggtgtc cagagagata tggatgcgtg tatggtctcg agatgaagat
      481 atcacggagt atcagagcat tctggctgca gcagtgaagg ctggaatgtc cacagcgcaa
      541 gcccaacact ttctggagaa gatctccaca caacaggtga agaacaagct cattgagaac
      601 acggatgcag cctgcaaata tggggccttt gggctaccca ccactgttgc ccatgtggat
      661 ggtaaaacct acatgttatt tgggtctgac cgcttggagt tgctagctta cctgctagga
      721 gagaagtgga tgggccctgt acccccaact gcgaatgcca gactttaaga ctgccttaca
      781 gagtaatctt tgatttctcc atctgatgtg gccctgggag ctggagcaag agtccacctt
      841 tagctgtgcc tgcctttact tctgtgcctc acaagtgcct tttgaaaagc cttaaattct
      901 gcattcccat aaaataaagt tgatgccacc
//
