LOCUS       NM_008179               2508 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus G1 to S phase transition 2 (Gspt2), mRNA.
ACCESSION   NM_008179
VERSION     NM_008179.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2508)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2508)
  AUTHORS   Li,X., Rayman,J.B., Kandel,E.R. and Derkatch,I.L.
  TITLE     Functional role of Tia1/Pub1 and Sup35 prion domains: directing
            protein synthesis machinery to the tubulin cytoskeleton
  JOURNAL   Mol Cell 55 (2), 305-318 (2014)
   PUBMED   24981173
REFERENCE   3  (bases 1 to 2508)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 2508)
  AUTHORS   Oeschger,F.M., Wang,W.Z., Lee,S., Garcia-Moreno,F., Goffinet,A.M.,
            Arbones,M.L., Rakic,S. and Molnar,Z.
  TITLE     Gene expression analysis of the embryonic subplate
  JOURNAL   Cereb Cortex 22 (6), 1343-1359 (2012)
   PUBMED   21862448
REFERENCE   5  (bases 1 to 2508)
  AUTHORS   Hoshino,S., Imai,M., Mizutani,M., Kikuchi,Y., Hanaoka,F., Ui,M. and
            Katada,T.
  TITLE     Molecular cloning of a novel member of the eukaryotic polypeptide
            chain-releasing factors (eRF). Its identification as eRF3
            interacting with eRF1
  JOURNAL   J Biol Chem 273 (35), 22254-22259 (1998)
   PUBMED   9712840
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL645466.12 and AW125523.1.
            
            On Jan 29, 2005 this sequence version replaced NM_008179.1.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2052              AL645466.12        94808-96859
            2053-2508           AW125523.1         1-456               c
FEATURES             Location/Qualifiers
     source          1..2508
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 41.63 cM"
     gene            1..2508
                     /gene="Gspt2"
                     /note="G1 to S phase transition 2"
                     /db_xref="GeneID:14853"
                     /db_xref="MGI:MGI:1316727"
     exon            1..2494
                     /gene="Gspt2"
                     /inference="alignment:Splign:2.1.0"
     CDS             189..2087
                     /gene="Gspt2"
                     /note="eRF3b; G1 to S phase transition protein 2 homolog;
                     eukaryotic peptide chain release factor subunit 3b"
                     /codon_start=1
                     /product="eukaryotic peptide chain release factor
                     GTP-binding subunit ERF3B"
                     /protein_id="NP_032205.2"
                     /db_xref="CCDS:CCDS41064.1"
                     /db_xref="GeneID:14853"
                     /db_xref="MGI:MGI:1316727"
                     /translation="MDLGSSSDSAPDCWDQVDMEAPGSAPSGDGIAPAAMAAAEAAEA
                     EAQRKHLSLAFSSQLNIHAKPFVPSVSAAEFVPSFLPGSAQPPAPTASSCDETCIGGA
                     GEPEGKRMEWGAPVEPSKDGPLVSWEGSSSVVTMELSEPVVENGEVEMALEESWELKE
                     VSEAKPEASLGDAGPPEESVKEVMEEKEEVRKSKSVSIPSGAPKKEHVNVVFIGHVDA
                     GKSTIGGQIMFLTGMVDRRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVG
                     RAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTR
                     EHAMLAKTAGVKYLIVLINKMDDPTVDWSSERYEECKEKLVPFLKKVGFSPKKDIHFM
                     PCSGLTGANIKEQSDFCPWYTGLPFIPYLDSLPNFNRSIDGPIRLPIVDKYKDMGTVV
                     LGKLESGSIFKGQQLVMMPNKHSVEVLGIVSDDAETDFVAPGENLKIRLKGIEEEEIL
                     PGFILCEPSNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVD
                     KKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKV
                     LKLVPEKD"
     regulatory      2459..2464
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gspt2"
                     /note="hexamer: AATAAA"
     polyA_site      2484
                     /gene="Gspt2"
                     /note="major polyA site"
ORIGIN      
        1 gagcggccat atctgccgcc gccgcagctg tgagtgcagc atctgcgctt agctgcctcc
       61 gcgccgctaa ggttcgcgtc gctcgcccgt ggcccgtggc tgttcctgcc ttactaccac
      121 cggtagaacc ctctcctcct gacctgccta cctcgctcct tctccgccgc accccggctg
      181 ctcacaccat ggatctcggc agcagcagcg actcggctcc cgactgctgg gatcaggtgg
      241 acatggaagc cccgggttcg gctccgagcg gggatggaat cgcccccgca gccatggcag
      301 cggctgaggc cgcggaagcc gaggcccagc gcaagcatct cagcttggcc ttcagcagtc
      361 agctcaacat ccacgccaaa cctttcgtgc ctagcgtaag cgcagcggag ttcgtgccgt
      421 ccttcctgcc tggatcggcc cagccgcccg cccccacagc ctccagctgc gacgaaacct
      481 gcatcggtgg cgccggggag cctgaaggta aacggatgga atggggagca cctgtagaac
      541 cttccaaaga tggcccttta gtgtcgtggg agggttccag ttcagttgtt accatggaac
      601 tttcagaacc tgttgtagaa aatggagagg tggagatggc cctagaagaa tcttgggagc
      661 ttaaagaagt gagtgaagca aagcctgagg cttctttggg agatgcaggg cccccagaag
      721 aaagtgtcaa ggaagtgatg gaggagaaag aggaagtaag gaaatcaaaa tctgtgtcca
      781 taccatcagg tgcacctaag aaagaacacg taaatgtggt cttcattggg catgtggatg
      841 ctggcaagtc aaccattgga ggacaaataa tgtttttgac aggaatggtt gacagaagga
      901 cacttgagaa atacgaacga gaagctaagg agaagaatag agagacctgg tacttgtcct
      961 gggccttaga tacaaaccag gaagaacgag acaagggtaa aacagtggaa gtgggccgtg
     1021 cgtattttga aacggaaaag aagcatttca caatcctaga tgcccctggc cacaagagtt
     1081 ttgtcccaaa tatgattggc ggtgcctctc aagccgattt agctgtgctg gtgatctctg
     1141 ccaggaaagg ggaatttgag actggatttg aaaaaggtgg acagacaaga gaacatgcaa
     1201 tgctggccaa aacagcaggg gtaaaatact taatagtgct tattaataag atggatgacc
     1261 ccacagtaga ttggagcagt gagcgatatg aagaatgtaa agaaaaactg gtgccctttt
     1321 tgaaaaaagt tggtttcagt ccaaaaaagg acattcactt tatgccctgc tcaggactga
     1381 ctggagcaaa tattaaagag caatctgatt tctgtccttg gtacaccgga ttaccattta
     1441 ttccgtattt ggatagtttg ccaaacttca acagatcaat tgatgggcca attaggttgc
     1501 caattgtgga taagtacaag gatatgggca ctgtggtcct gggtaagctg gaatcaggat
     1561 ccatttttaa aggccagcag cttgtgatga tgccaaacaa gcacagtgtg gaagttctag
     1621 gaatcgtttc tgatgatgcc gagactgatt ttgtagctcc aggtgaaaac ctcaaaatca
     1681 gactgaaagg gattgaagag gaagagattc ttccaggctt catactttgt gaacccagta
     1741 atctttgcca ttccggacgc acatttgatg ttcagatagt gatcattgag cacaagtcta
     1801 tcatctgccc aggttataat gcggtgcttc acattcatac ttgtattgag gaggttgaaa
     1861 taacagcctt gatctcctta gtagacaaaa agtcaggaga aaaaagcaag acacggcccc
     1921 gctttgtgaa gcaagaccaa gtgtgcattg cccggttaag gacagcagga actatctgcc
     1981 tggagacatt taaagatttt cctcagatgg gtcgttttac tttaagagat gagggtaaaa
     2041 caatcgccat tggaaaagtt ctgaagctgg tcccagagaa ggactaagca atctcttttg
     2101 atgcctctgc accataatgt gtgaaagatt gaccgcaacc tactgcccat tgacaaactt
     2161 gtgcccatat tttgcagaga aatttcacag caaaaatcca cgtgttgtca gctttctcat
     2221 gttgagactt cagtcgtgtc actcctgaat gcatactcca gtttcctccc tctatagcac
     2281 tctgcttcct tggacaaatc agtaatagct ttgtaagtga tgtgtgtgta attgcctaca
     2341 gtcctaaaaa gaatatattt taaagttttc atttccgttt gggatatcta gacatccttt
     2401 gttctgtggg gaacagtcag tgttggtgtg tgtatatgtt gaagataact aacatgtaaa
     2461 taaaacgttg cgtttgaaac ttcagcattt gaaaaaaaaa aaaaaaaa
//
