LOCUS       NM_001145896            6584 bp    mRNA    linear   ROD 29-JUL-2024
DEFINITION  Mus musculus genetic suppressor element 1, coiled-coil protein
            (Gse1), transcript variant 2, mRNA.
ACCESSION   NM_001145896
VERSION     NM_001145896.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6584)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6584)
  AUTHORS   Dali,O., D'Cruz,S., Legoff,L., Diba Lahmidi,M., Heitz,C.,
            Merret,P.E., Kernanec,P.Y., Pakdel,F. and Smagulova,F.
  TITLE     Transgenerational epigenetic effects imposed by neonicotinoid
            thiacloprid exposure
  JOURNAL   Life Sci Alliance 7 (2), e202302237 (2023)
   PUBMED   37973188
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6584)
  AUTHORS   Astrof,S., Arriagada,C., Saijoh,Y., Francou,A., Kelly,R.G. and
            Moon,A.
  TITLE     Aberrant differentiation of second heart field mesoderm prefigures
            cellular defects in the outflow tract in response to loss of FGF8
  JOURNAL   Dev Biol 499, 10-21 (2023)
   PUBMED   37060937
REFERENCE   4  (bases 1 to 6584)
  AUTHORS   Hiver,S., Shimizu-Mizuno,N., Ikawa,Y., Kajikawa,E., Sai,X.,
            Nishimura,H., Takaoka,K., Nishimura,O., Kuraku,S., Tanaka,S. and
            Hamada,H.
  TITLE     Gse1, a component of the CoREST complex, is required for placenta
            development in the mouse
  JOURNAL   Dev Biol 498, 97-105 (2023)
   PUBMED   37019373
  REMARK    GeneRIF: Gse1, a component of the CoREST complex, is required for
            placenta development in the mouse.
REFERENCE   5  (bases 1 to 6584)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6584)
  AUTHORS   Bailey,P.J., Klos,J.M., Andersson,E., Karlen,M., Kallstrom,M.,
            Ponjavic,J., Muhr,J., Lenhard,B., Sandelin,A. and Ericson,J.
  TITLE     A global genomic transcriptional code associated with CNS-expressed
            genes
  JOURNAL   Exp Cell Res 312 (16), 3108-3119 (2006)
   PUBMED   16919269
REFERENCE   7  (bases 1 to 6584)
  AUTHORS   Imai,K., Kawai,M., Tada,M., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Temporal change in mKIAA gene expression during the early stage of
            retinoic acid-induced neurite outgrowth
  JOURNAL   Gene 364, 114-122 (2005)
   PUBMED   16169686
  REMARK    GeneRIF: Some mKIAA genes are apparently relevant to retinoic
            acid-induced neurite outgrowth. (mKIAA gene)
REFERENCE   8  (bases 1 to 6584)
  AUTHORS   Carninci,P., Waki,K., Shiraki,T., Konno,H., Shibata,K., Itoh,M.,
            Aizawa,K., Arakawa,T., Ishii,Y., Sasaki,D., Bono,H., Kondo,S.,
            Sugahara,Y., Saito,R., Osato,N., Fukuda,S., Sato,K., Watahiki,A.,
            Hirozane-Kishikawa,T., Nakamura,M., Shibata,Y., Yasunishi,A.,
            Kikuchi,N., Yoshiki,A., Kusakabe,M., Gustincich,S., Beisel,K.,
            Pavan,W., Aidinis,V., Nakagawara,A., Held,W.A., Iwata,H., Kono,T.,
            Nakauchi,H., Lyons,P., Wells,C., Hume,D.A., Fagiolini,M.,
            Hensch,T.K., Brinkmeier,M., Camper,S., Hirota,J., Mombaerts,P.,
            Muramatsu,M., Okazaki,Y., Kawai,J. and Hayashizaki,Y.
  TITLE     Targeting a complex transcriptome: the construction of the mouse
            full-length cDNA encyclopedia
  JOURNAL   Genome Res 13 (6B), 1273-1289 (2003)
   PUBMED   12819125
REFERENCE   9  (bases 1 to 6584)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
REFERENCE   10 (bases 1 to 6584)
  AUTHORS   Gudkov,A.V., Kazarov,A.R., Thimmapaya,R., Axenovich,S.A., Mazo,I.A.
            and Roninson,I.B.
  TITLE     Cloning mammalian genes by expression selection of genetic
            suppressor elements: association of kinesin with drug resistance
            and cell immortalization
  JOURNAL   Proc Natl Acad Sci U S A 91 (9), 3744-3748 (1994)
   PUBMED   8170981
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY766823.1, AK042915.1, BC043094.1 and AI854638.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR and
            contains an alternate 5' coding region, compared to variant 1. The
            encoded isoform (2) has a distinct N-terminus and is shorter than
            isoform 1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK042915.1, AK154829.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-55                BY766823.1         1-55
            56-292              AK042915.1         3-239
            293-6563            BC043094.1         425-6695
            6564-6584           AI854638.1         1-21                c
FEATURES             Location/Qualifiers
     source          1..6584
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 69.69 cM"
     gene            1..6584
                     /gene="Gse1"
                     /gene_synonym="2210013I18Rik; mKIAA0182"
                     /note="genetic suppressor element 1, coiled-coil protein"
                     /db_xref="GeneID:382034"
                     /db_xref="MGI:MGI:1098275"
     exon            1..154
                     /gene="Gse1"
                     /gene_synonym="2210013I18Rik; mKIAA0182"
                     /inference="alignment:Splign:2.1.0"
     exon            155..373
                     /gene="Gse1"
                     /gene_synonym="2210013I18Rik; mKIAA0182"
                     /inference="alignment:Splign:2.1.0"
     exon            374..573
                     /gene="Gse1"
                     /gene_synonym="2210013I18Rik; mKIAA0182"
                     /inference="alignment:Splign:2.1.0"
     exon            574..746
                     /gene="Gse1"
                     /gene_synonym="2210013I18Rik; mKIAA0182"
                     /inference="alignment:Splign:2.1.0"
     exon            747..944
                     /gene="Gse1"
                     /gene_synonym="2210013I18Rik; mKIAA0182"
                     /inference="alignment:Splign:2.1.0"
     exon            945..1136
                     /gene="Gse1"
                     /gene_synonym="2210013I18Rik; mKIAA0182"
                     /inference="alignment:Splign:2.1.0"
     exon            1137..1459
                     /gene="Gse1"
                     /gene_synonym="2210013I18Rik; mKIAA0182"
                     /inference="alignment:Splign:2.1.0"
     exon            1460..1784
                     /gene="Gse1"
                     /gene_synonym="2210013I18Rik; mKIAA0182"
                     /inference="alignment:Splign:2.1.0"
     exon            1785..2407
                     /gene="Gse1"
                     /gene_synonym="2210013I18Rik; mKIAA0182"
                     /inference="alignment:Splign:2.1.0"
     exon            2408..2520
                     /gene="Gse1"
                     /gene_synonym="2210013I18Rik; mKIAA0182"
                     /inference="alignment:Splign:2.1.0"
     exon            2521..2791
                     /gene="Gse1"
                     /gene_synonym="2210013I18Rik; mKIAA0182"
                     /inference="alignment:Splign:2.1.0"
     exon            2792..2899
                     /gene="Gse1"
                     /gene_synonym="2210013I18Rik; mKIAA0182"
                     /inference="alignment:Splign:2.1.0"
     exon            2900..3271
                     /gene="Gse1"
                     /gene_synonym="2210013I18Rik; mKIAA0182"
                     /inference="alignment:Splign:2.1.0"
     exon            3272..3550
                     /gene="Gse1"
                     /gene_synonym="2210013I18Rik; mKIAA0182"
                     /inference="alignment:Splign:2.1.0"
     exon            3551..3654
                     /gene="Gse1"
                     /gene_synonym="2210013I18Rik; mKIAA0182"
                     /inference="alignment:Splign:2.1.0"
     exon            3655..6569
                     /gene="Gse1"
                     /gene_synonym="2210013I18Rik; mKIAA0182"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6544..6549
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gse1"
                     /gene_synonym="2210013I18Rik; mKIAA0182"
                     /note="hexamer: AATAAA"
     polyA_site      6569
                     /gene="Gse1"
                     /gene_synonym="2210013I18Rik; mKIAA0182"
                     /note="major polyA site"
ORIGIN      
        1 gtttcttggc ccaggccccg gaagctccac ctccccgagc ggcggagccg ccgccgcaca
       61 gccccgggtg agataagcag ttcagacaaa cccgggcgac ggtggctccg gcatgtgtca
      121 ggagcggtgg agcagcgggg ccctggcatg aaaggcatga gccatgagcc caagtcccct
      181 tccataggga tgctttccac ggcgaccagg accaccgcca ccgtcaaccc cctcaccccc
      241 tcgccactca atggcgccct ggtgcccacc ggtagcccgg ccaccagcag tacgctgtcg
      301 gcccaggccg ctccatcctc cagctttgct gccgcactgc gcaagctcgc caaacaggca
      361 gaggagccca gagggtcctc actgagcagc gagtcatctc cagtgtcctc tccagccacc
      421 aaccatagct ctccagctag cacgcccaaa cgagtgccca tgggccccat catcgtcccc
      481 cccgggggtc acagtgtccc cagcactccc ccagtggtca ctattgcccc cactaaaacc
      541 gtcaatggag tctggagaag cgagagccgc caggactctg gctcacgagg cagcagcagt
      601 ggtcgggagc gcctattggt ggagccacct ctcgcccagg aaaaggctgc gggccccgcc
      661 atcccctccc acctactcag caccccgtac ccctttggcc tttcccccgg ctcagttgta
      721 caggactccc gcttccaacc actcaacctc cagcggcctg tgcaccatgt ggtgcccccc
      781 agcacggtga ctgaggacta cttgagaagc ttccggccct accacactgc tgaagactta
      841 cgcatgtcct ccttgcctcc gcttggcctg gacccagcca ccgccgcagc ctactatcac
      901 cccagctacc tggccccaca cccattcccc cacccggcct tcaggatgga tgactcctat
      961 tgcctgtcag ccttaaggtc tccgttctac cccatcccca cccctggctc cctgcctcca
     1021 ctgcatccgt cggcgatgca cctgcatctc tccggcgtac ggtatcctcc tgagctctcc
     1081 cactcgtccc tggcggcgct acactcggag cggatgtcca gcctcagtgc agagaggttg
     1141 caaatggacg aggaactgcg gcgggagaga gagcgagagc gggaacggga acgggaggcc
     1201 gaccgggagc gggagaagga gcgggagcgg gagcagcggg agaaggagcg ggagaaggag
     1261 ctggagcgcg agcgggagaa ggaacgggag cgcgagctgg agcggcagcg ggagcagcgg
     1321 gcgagggaga aggagctgct ggctgccaag gccttagagc ccaccacctt cctgcctgtg
     1381 gccgagctgc acggactccg aggtcacagc acggaggagc ggcccaagcc ctcggagcag
     1441 ctgaccccaa cccgagcaga gaagctgaag gacgtgggct tgcaggcgcc caagcccgtg
     1501 cagcaccctc tgcacccagt gcctgcccca caccacacgg tgcccagcct catctccagc
     1561 cacggcatct tctctctgcc tggaagcagc gccaccaccg ccctgctgat ccagcgcacc
     1621 aacgaggagg agaagtggct ggcacggcag cgccgcctgc ggcaggagaa ggaagaccgc
     1681 cagtcccagg tgtccgagtt ccggcagcag gtcctggagc agcacctaga cctgggccgg
     1741 cccctggtgc ccacagaggc ggagcacagg cccgagagca ccaggccagg aacaaaccgg
     1801 catgagcagg gcagccgtga acccccacag cactttggtg gccctccacc cctcatctca
     1861 cccaagcccc agcagcacac cgtacccaca gccctctgga acccagtgtc tctgatggac
     1921 aatgctctgg agacgcggcg ggccgagagc cactctctgc atagccaccc gactgctttt
     1981 gagcccagcc gccaggccgc cgtgccactg gtgaaggtgg agcgagttta ttgctcagag
     2041 aaggcagagg agccccggaa gcgtgaggcc acaccactgg acaaatacca gccaccacca
     2101 ccaccaccac caccgcggga ggcaggaagt ctggagcctc agacctttcc ccacggacct
     2161 gggcctttcc ttactgaact tgaaaagtca acacagacca tcttgggcca gcagcggccc
     2221 tctctttccc aggcaacctc cttcggggag ctcagtgggc ctctgaaacc aggctctccg
     2281 tactgccacc ccacagcgag gggccccgat ccagcctaca tctacgatga gtttcttcag
     2341 cagcgacgga agctggtcag caaactggac ctggaggaac gcaggcggcg cgaggcccag
     2401 gagaaagggt actactacga cctcgatgac tcgtacgacg agagtgacga ggaggaggtc
     2461 agggcacacc tccgctgtgt ggctgagcag ccgcccctca aactggacac atcctcggag
     2521 aagctagagt tcttgcaact ttttggcttg accacccaac agcagaagga ggaactggtg
     2581 gcgcagaagc gccggaagcg gaggcggatg ctcagagaga gaagcccgtc gccacctgcc
     2641 gttcagtgca agcgacagac gccttccccc aggctggctc tgtccacccg ctacagcccc
     2701 gacgagatga acaacagccc caactttgag gagaagagga agttcctgac cttcttcaac
     2761 ttgacgcaca tcagtgcgga gaagaggaaa gacaaagaga ggcttgttga aatgctccga
     2821 gccatgaagc agagagcact gtccgcagca gactcagtga caaactcttc gagggacagt
     2881 cctcccgtct ccctgagtga accagccaca cagccagctc ctctagagac ggatcagcct
     2941 gtcggggtcc ctgcctcctt gtcagatgtc ccaaagacca cggagaccgg gagactggaa
     3001 cagctccggc cccaggagct cttgagagtc caggagccgg ctcctcccag tggtgagaag
     3061 gccaggctga gcgaggcccc tggtggcaag aagagcctga gcatgctcca ttacctccgg
     3121 ggcgccgcgc ccaaggacat tcctgtgccg ttgtctcaca gcatcaacgg gaagagcaag
     3181 ccctgggagc ctttcgtggc cgaagagttt gcacatcaat tccacgagtc cgtgctgcag
     3241 tccacacaga aggctctgca gaagcataaa gggaactctg ctttgctatc tgcagagcag
     3301 agccacaaag tcgacacggc aatccactac aacattcccg agctgcagtc ctccagcagg
     3361 gtccccttgc cccagcacaa tggacaacag gagcctccaa tggggaggaa gggccctcct
     3421 atgcaggagg cggaccagga ctctgaggag gactctgagg aggacagcga ggaggaagct
     3481 gaggaagccc cgaggcgcca gtggcaaggg attgaggcaa tctttgaagc ttaccaggaa
     3541 cacatagaag agcaaaacct ggagcggcag gtgctgcaga cgcagtgccg gcggttggag
     3601 gcgcagaact acagcctcag cctgactgcg gagcagctgt ctcacagcat ggcggagctt
     3661 cggagtcaga aacagaagat ggtctctgag cgggagcggc tccaggcgga gctggaccac
     3721 ttgcggaagt gccttgcctt gcccaccatg cactggccta ggggctactt taagggatat
     3781 ccgaggtgac ggtttccctt gcactaggct gaacctatag tatagaaata ttatctattt
     3841 tattaccttg aatatttaat atttttcact gggaggtttg aagcttacaa attgagaacg
     3901 tgccatgcat gaaacaaagg gttccaggct ccagagagga gatcacctcg acgccaatgt
     3961 caccgaggca cctgtctcag ctaggactca gtttctcttt ctgaggtcgg cgttatttcc
     4021 tctctccccc cacgtcatcc tcctccgaca ctgacgtcca ccgtgcatgt ggctgaggga
     4081 gagagccagc tggttgtttc tggtatagct gtgccacgag agcccagctt gctgttgctg
     4141 cggccctggg gtttaacctc ttcctgccag gagcgggact aatgcgccgg gaaggctggg
     4201 tgcgtacaag caaagggctc cccatcagtc ccgtccgtct gtcgccttcc cgcaagcgtc
     4261 atcatcgaag ccactgctcc tgggagcaca caagcttctc cctggaacag ctcttaggaa
     4321 aagaggcaaa cccacaccca aaagtacctt gttttccttg gggaagatgc gtggagctgt
     4381 ccacagatag cctacccact ggattgctac cgccgtgtgt ggtgttttca tacaaacgta
     4441 cgttttgaga gaaaagtcaa aggtgcttca gccttgtact gtgtatatat taaaaaaaaa
     4501 gttttgtatg tttttattac tttaattatt gttataaaaa gcctgccatt tttaatatgt
     4561 ggtttgggga attttgtttg tttttcctgt ttgggggttt tctttggttt ttttgtttgt
     4621 ttgtttctgt ttttctggat ttaaaaaaaa agaaaacctt gcttttagtg tttgtactgc
     4681 tgctggtcag aatgttgtta actgctcagt tctaggaagc aggagagctc gcttgtgcag
     4741 tgtcccacac agcagggctg aggggcctag ggctgcctgc tctccaaagc agatgaccca
     4801 tgtgcggcag ggactcggca aagctgtgag gagctgagct ccggagacag gcacagctct
     4861 ggcagaaagc tcaacgctaa gggatctcct tcccagtttc agcacttcag tcagggctga
     4921 ccaacttgaa aagagcctcc gactgtcctc catcggacag gggaagagga ggccgagccc
     4981 acccttagcc accaggctca gtggctgtac agagcagctg gctgacatct gtccctgctc
     5041 cacccctgcc cctacccgca cccctctggt tctcagcaaa ctcagacaag gcagtgccac
     5101 caggcctgtc agcaaagcac cttcctctgc ccacagccag tcagagaaaa cgatccaaag
     5161 gagggcagag gccgcacacc ctgggccgag tcctgcccga cttcccagtt aaatgctgct
     5221 tgtgcccagt gctgctttcc caagctcacc ccacctccat gactagaagc ttctgcaaat
     5281 ctgcttggta aatgtctcct gggaaaggca gaacccataa cttaaagaca cgcacagtcc
     5341 cttccattgt cccacaggag ttcctctggc tgagtatgcc atccagagca agcgatgccc
     5401 tcccaggtca gtctggggca caagctgagc cgctgactag caatgcctac agcctttccc
     5461 aatgcccttg cctgccctgg agcttctagg gccacctcta gcatctggag accgaatatc
     5521 cccatgctca gaagtaaagt gacaatcaga accaggtaca agccagtaaa gcggcagatg
     5581 actgccactc agcccacata cggcattctt cccatcccac agtcttagag ccagatgagg
     5641 ctaacaagac cacagtagcc cccttcccag gtaccacact gtccctggag atccctccag
     5701 cctagccctg ctatagatct gctctagact gtgaaatcag catgtatgtg aaaaatccca
     5761 gtccttgacc atgtctccca ctccacctgc aagtgattgc tgccatctgt cctgggtggg
     5821 atgcaccgag ctagtcacgg gtgtcggatc agatctttta aaaacacttg tctcatgtaa
     5881 ttgagacccg ccaccatcgc agatgagtga caagagagaa ggctgtcaac acttcggtac
     5941 atggtgatct taaaaacacc cacctgcacc atcacaccag actgtaccac tagggcatcc
     6001 agaacaagcc ccaccctaac agtgggggca gggagggtac agccaggctc acagcactga
     6061 gagtctcaac cagctaagct aaattgcaag ctagatgcct cctgcccctg ccctcagctg
     6121 cccaggcccc agcatggaga tggcctgcac agcaggctca gcacctctga ggtgtgcatt
     6181 agccacttat agcagcagtc tgtactcttt caagtacgca agctttgact tcactacttg
     6241 ctgtagcctg tccccactgt ctatccagtg cttacttcaa ccctagaggc tgccttgacc
     6301 cgaggaggca tctcactggt tccgtacttg tgtgtgccct acgcctcact gctggggccc
     6361 tggacccaga cccaggcagg agggccgacg ggtgcctcgg tcgctctggg ggcagtttag
     6421 atgctgtgaa attaaacccg ttctaagtgt acttgtttga attaactgta ttgtaatatt
     6481 atttgttgaa tgtagtaatt aggtatttat gaatatattg ctgtaatttc tgacatcccg
     6541 aaaaataaaa tcttcctaaa tcatgttaaa aaaaaaaaaa aaaa
//
