LOCUS       NM_153419               1905 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus glutamate-rich WD repeat containing 1 (Grwd1),
            transcript variant 1, mRNA.
ACCESSION   NM_153419 XM_001002533
VERSION     NM_153419.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1905)
  AUTHORS   Ding,H., Feng,Z. and Hu,K.
  TITLE     GRWD1 Over-Expression Promotes Gastric Cancer Progression by
            Activating Notch Signaling Pathway via Up-Regulation of ADAM17
  JOURNAL   Dig Dis Sci 69 (3), 821-834 (2024)
   PUBMED   38172445
  REMARK    GeneRIF: GRWD1 Over-Expression Promotes Gastric Cancer Progression
            by Activating Notch Signaling Pathway via Up-Regulation of ADAM17.
REFERENCE   2  (bases 1 to 1905)
  AUTHORS   Pritsker,M., Doniger,T.T., Kramer,L.C., Westcot,S.E. and
            Lemischka,I.R.
  TITLE     Diversification of stem cell molecular repertoire by alternative
            splicing
  JOURNAL   Proc Natl Acad Sci U S A 102 (40), 14290-14295 (2005)
   PUBMED   16183747
REFERENCE   3  (bases 1 to 1905)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   4  (bases 1 to 1905)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BQ886252.1, BC083143.1 and DT904438.1.
            
            On Dec 27, 2007 this sequence version replaced NM_153419.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK077611.1, BC008121.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164137
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-620               BQ886252.1         4-623
            621-1650            BC083143.1         609-1638
            1651-1885           DT904438.1         466-700
            1886-1895           BC083143.1         1874-1883
            1896-1905           DT904438.1         710-719
FEATURES             Location/Qualifiers
     source          1..1905
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 29.53 cM"
     gene            1..1905
                     /gene="Grwd1"
                     /gene_synonym="A301; Grwd; Wdr28"
                     /note="glutamate-rich WD repeat containing 1"
                     /db_xref="GeneID:101612"
                     /db_xref="MGI:MGI:2141989"
     exon            1..195
                     /gene="Grwd1"
                     /gene_synonym="A301; Grwd; Wdr28"
                     /inference="alignment:Splign:2.1.0"
     exon            196..313
                     /gene="Grwd1"
                     /gene_synonym="A301; Grwd; Wdr28"
                     /inference="alignment:Splign:2.1.0"
     exon            314..476
                     /gene="Grwd1"
                     /gene_synonym="A301; Grwd; Wdr28"
                     /inference="alignment:Splign:2.1.0"
     exon            477..690
                     /gene="Grwd1"
                     /gene_synonym="A301; Grwd; Wdr28"
                     /inference="alignment:Splign:2.1.0"
     exon            691..833
                     /gene="Grwd1"
                     /gene_synonym="A301; Grwd; Wdr28"
                     /inference="alignment:Splign:2.1.0"
     exon            834..1031
                     /gene="Grwd1"
                     /gene_synonym="A301; Grwd; Wdr28"
                     /inference="alignment:Splign:2.1.0"
     exon            1032..1902
                     /gene="Grwd1"
                     /gene_synonym="A301; Grwd; Wdr28"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1876..1881
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Grwd1"
                     /gene_synonym="A301; Grwd; Wdr28"
                     /note="hexamer: AATAAG"
     polyA_site      1895
                     /gene="Grwd1"
                     /gene_synonym="A301; Grwd; Wdr28"
                     /note="major polyA site"
ORIGIN      
        1 gttcgaagat ggcggcgcgc aagggccgga gtcgcacgtg tgaaaccgga gaacccatgg
       61 aggctgaaac ctgcgaccca ggaaccgaag gcccatccca ggtctacctg cccggcagag
      121 ggccgccact gagcgaggga gaggagctgg taatggatga agaggcctac gtgctgtacc
      181 atcgtgcgca aactggcgcc ccttgtctca gctttgacat agttcgagat cacttgggcg
      241 acaaccggac agagctccct ctcagtcttt acctgtgtgc gggaacccag gcggagagcg
      301 cccagagcaa tagactgatg atgcttcgga tgcacaatct ccatggcacc aggccgtcac
      361 cctcagaggg cagtgatgac gatgaggaag atgaagatga agaggatgag gaggagcaga
      421 aacctcagct ggaactggcc atggttcctc actacggtgg catcaaccga gttcgggtat
      481 cttggctggg ggaggaacct gtggctggag tatggtcaga gaagggccaa gtggaggtgt
      541 tcgcactgcg gcggctcctg caggtggtgg atgaccccca ggccctggcc atcttcctcc
      601 gagatgagca ggcccgaata aaacccatct tctcctttgc tggccacatg ggagagggct
      661 ttgctcttga ctggtcccct cgggtgcccg gccgcttgct gactggtgac tgtcagaaga
      721 acgtccacct ctggacaccc acggagggtg gttcctggaa tgtggaccag aggccgtttg
      781 tgggccacac acggtctgtg gaggatctgc agtggtcacc aactgaggac acggtgtttg
      841 cctcctgctc tgctgatgcc tctattcgca tctgggacat ccgagcagcc ccaggcaagg
      901 cctgcatgct caccacagcc actgcccatg atggagatgt taatgtcatc agctggagcc
      961 gcagggagcc cttcctgctc agcggtgggg atgatggtgc cctcaaagtc tgggacctgc
     1021 gacagtttaa gtctggctcc cctgtggcca ccttcaagca acatatggcc cccgtgacct
     1081 ctgttgaatg gcaccctcag gacagtgggg tcttcgcagc ctcaggtgct gacaaccaga
     1141 tcacacaatg ggacctggca gttgaacggg acccagagtc gggggagaca gagacagacc
     1201 ctgggctggc ggcactcccc cagcagttgc tgttcgtgca ccaaggtgag actgacctga
     1261 aggagctaca ctggcaccca cagtgcccgg gggtcctgat cagcaccgcc ctgtcaggct
     1321 tcaccgtctt ccgcaccatc agtgtttgag gtggccaaca cttggcctca agacttggct
     1381 ccacatggga actggatcgg ttaacttggc aaggatcatt aggcctgtag actgcacctc
     1441 aggaaggaag acttgttcaa ctggcctacg tggaacagaa ggaacggact ctactgacct
     1501 ggtatctcta aggatttgga ttgacccttg gccctgcctt acaccaaaga ctaggtgcag
     1561 gcaaagatcc ttgcctgtcc cagatacggc ctcaggatga gatttttgtc agtgttgact
     1621 cctggcttga ccccaaggac ctctgaccag ggacctaatt ctggctgttg atcaacttca
     1681 ggaactttaa gggttttgcc atagctgggc caagtctggg tctgtgtcac tccagtggaa
     1741 tttaattctc tctctgcctt ctggccagtt agatttggtt gagatccaag tagggagcca
     1801 tctggggtgc cctcctgtgc tgaccactac tgtactggag gagggtctgg ggcttctgct
     1861 gtaataaagg accacaataa ggccccagac accaagctac aaaaa
//
