LOCUS       NM_001033351            7667 bp    mRNA    linear   ROD 07-FEB-2025
DEFINITION  Mus musculus glutamate receptor ionotropic, NMDA3A (Grin3a),
            transcript variant 2, mRNA.
ACCESSION   NM_001033351
VERSION     NM_001033351.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7667)
  AUTHORS   Hurley,E.P., Mukherjee,B., Fang,L.Z., Barnes,J.R., Barron,J.C.,
            Nafar,F., Hirasawa,M. and Parsons,M.P.
  TITLE     GluN3A and Excitatory Glycine Receptors in the Adult Hippocampus
  JOURNAL   J Neurosci 44 (42), e0401242024 (2024)
   PUBMED   39256046
  REMARK    GeneRIF: GluN3A and Excitatory Glycine Receptors in the Adult
            Hippocampus.
            Erratum:[J Neurosci. 2024 Nov 20;44(47):e2031242024. doi:
            10.1523/JNEUROSCI.2031-24.2024.. PMID: 39542731]
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7667)
  AUTHORS   Lo Giudice,Q., Wagener,R.J., Abe,P., Frangeul,L. and Jabaudon,D.
  TITLE     Developmental emergence of first- and higher-order thalamic neuron
            molecular identities
  JOURNAL   Development 151 (18) (2024)
   PUBMED   39348458
REFERENCE   3  (bases 1 to 7667)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   4  (bases 1 to 7667)
  AUTHORS   Zhang,M., Kong,X., Chen,J., Liu,W., Liu,C., Dou,X., Jiang,L.,
            Luo,Y., Song,M., Miao,P., Tang,Y. and Xiu,Y.
  TITLE     Dysfunction of GluN3A subunit is involved in depression-like
            behaviors through synaptic deficits
  JOURNAL   J Affect Disord 332, 72-82 (2023)
   PUBMED   36997126
  REMARK    GeneRIF: Dysfunction of GluN3A subunit is involved in
            depression-like behaviors through synaptic deficits.
REFERENCE   5  (bases 1 to 7667)
  AUTHORS   Spirkova,A., Kovarikova,V., Sefcikova,Z., Pisko,J., Ksinanova,M.,
            Koppel,J., Fabian,D. and Cikos,S.
  TITLE     Glutamate can act as a signaling molecule in mouse preimplantation
            embryosdagger
  JOURNAL   Biol Reprod 107 (4), 916-927 (2022)
   PUBMED   35746896
REFERENCE   6  (bases 1 to 7667)
  AUTHORS   Kattenstroth,G., Tantalaki,E., Sudhof,T.C., Gottmann,K. and
            Missler,M.
  TITLE     Postsynaptic N-methyl-D-aspartate receptor function requires
            alpha-neurexins
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2607-2612 (2004)
   PUBMED   14983056
  REMARK    GeneRIF: decrease in NMDA-receptor activity in
            alpha-neurexin-deficient synapses
REFERENCE   7  (bases 1 to 7667)
  AUTHORS   Sucher,N.J., Kohler,K., Tenneti,L., Wong,H.K., Grunder,T.,
            Fauser,S., Wheeler-Schilling,T., Nakanishi,N., Lipton,S.A. and
            Guenther,E.
  TITLE     N-methyl-D-aspartate receptor subunit NR3A in the retina:
            developmental expression, cellular localization, and functional
            aspects
  JOURNAL   Invest Ophthalmol Vis Sci 44 (10), 4451-4456 (2003)
   PUBMED   14507892
REFERENCE   8  (bases 1 to 7667)
  AUTHORS   Andersson,O., Stenqvist,A., Attersand,A. and von Euler,G.
  TITLE     Nucleotide sequence, genomic organization, and chromosomal
            localization of genes encoding the human NMDA receptor subunits
            NR3A and NR3B
  JOURNAL   Genomics 78 (3), 178-184 (2001)
   PUBMED   11735224
REFERENCE   9  (bases 1 to 7667)
  AUTHORS   Das,S., Sasaki,Y.F., Rothe,T., Premkumar,L.S., Takasu,M.,
            Crandall,J.E., Dikkes,P., Conner,D.A., Rayudu,P.V., Cheung,W.,
            Chen,H.S., Lipton,S.A. and Nakanishi,N.
  TITLE     Increased NMDA current and spine density in mice lacking the NMDA
            receptor subunit NR3A
  JOURNAL   Nature 393 (6683), 377-381 (1998)
   PUBMED   9620802
REFERENCE   10 (bases 1 to 7667)
  AUTHORS   Billings-Gagliardi,S. and Adcock,L.H.
  TITLE     Hypomyelinated mutant mice IV: peripheral myelin in jp msd
  JOURNAL   Brain Res 225 (2), 309-317 (1981)
   PUBMED   7306792
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK138366.1, AK044171.1, AL732521.18 and AW494659.1.
            
            On Feb 1, 2013 this sequence version replaced NM_001033351.1.
            
            Transcript Variant: This variant (2) uses an alternate in-frame
            splice site in the 3' coding region, compared to variant 1. This
            results in a shorter protein (isoform 2), compared to isoform 1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK138366.1, SRR14777535.2117502.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-557               AK138366.1         2-558
            558-943             AK044171.1         534-919
            944-2855            AK044171.1         921-2832
            2856-3758           AK138366.1         2857-3759
            3759-7198           AL732521.18        115223-118662       c
            7199-7667           AW494659.1         1-469               c
FEATURES             Location/Qualifiers
     source          1..7667
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 26.72 cM"
     gene            1..7667
                     /gene="Grin3a"
                     /gene_synonym="6430537F04; A830097C19Rik; GluN3A;
                     mKIAA1973; NMDAR-L; NMDAR3A; NR3A"
                     /note="glutamate receptor ionotropic, NMDA3A"
                     /db_xref="GeneID:242443"
                     /db_xref="MGI:MGI:1933206"
     exon            1..1387
                     /gene="Grin3a"
                     /gene_synonym="6430537F04; A830097C19Rik; GluN3A;
                     mKIAA1973; NMDAR-L; NMDAR3A; NR3A"
                     /inference="alignment:Splign:2.1.0"
     CDS             689..4036
                     /gene="Grin3a"
                     /gene_synonym="6430537F04; A830097C19Rik; GluN3A;
                     mKIAA1973; NMDAR-L; NMDAR3A; NR3A"
                     /note="isoform 2 precursor is encoded by transcript
                     variant 2; N-methyl-D-aspartate receptor;
                     N-methyl-D-aspartate receptor subtype 3A; glutamate
                     receptor ionotropic, NMDA 3A"
                     /codon_start=1
                     /product="glutamate receptor ionotropic, NMDA 3A isoform 2
                     precursor"
                     /protein_id="NP_001028523.1"
                     /db_xref="CCDS:CCDS51175.1"
                     /db_xref="GeneID:242443"
                     /db_xref="MGI:MGI:1933206"
                     /translation="MRRLSLWWLLSRVCLLLPPPCALVLAGVPSSSSHPQPCQILKRI
                     GHAVRVGAVHLQPWTTAPRAASRAQDGGRAGAQRDEPESGTWRPPAPSQGARWLGSAL
                     HGRGPPGSRKLGEGAGTETLWPRDALLFAVENLNRVEGLLPYNLSLEVVMAIEAGLGD
                     LPLMPFSSPSSPWSSDPFSFLQSVCHTVVVQGVSALLAFPQSQGEMMELDLVSSVLHI
                     PVLSIVRHEFPRESQNPLHLQLSLENSLSSDADVTVSILTMNNWYNFSLLLCQEDWNI
                     TDFLLLTENNSKFHLESIINITANLSSTKDLLSFLQVQLENIRNSTPTMVMFGCDMGS
                     IRQIFEMSTQFGLSPPDLHWVLGDSQNVEELRTEGLPLGLIAHGKTTQSVFEYYVQDA
                     MELVARAVATATMIQPELALLPSTMNCMDVKTTNLTSGQYLSRFLANTTFRGLSGSIK
                     VKGSTIVSSENNFFIWNLQYDPMGKPMWTRLGSWQGGRIVMDSGIWPEQAQRHKTHFH
                     HPNKLHLRVVTLIEHPFVFTREVDDEGLCPAGQLCLDPMTNDSSILDSLFSSLHSSND
                     TVPIKFKKCCYGYCIDLLEQLAEDMNFDFDLYIVGDGKYGAWKNGHWTGLVGDLLSGT
                     ANMAVTSFSINTARSQVIDFTSPFFSTSLGILVRTRDTAAPIGAFMWPLHWTMWLGIF
                     VALHITAIFLTLYEWKSPFGMTPKGRNRNKVFSFSSALNVCYALLFGRTAAIKPPKCW
                     TGRFLMNLWAIFCMFCLSTYTANLAAVMVGEKIYEELSGIHDPKLHHPSQGFRFGTVR
                     ESSAEDYVRQSFPEMHEYMRRYNVPATPDGVQYLKNDPEKLDAFIMDKALLDYEVSID
                     ADCKLLTVGKPFAIEGYGIGLPPNSPLTSNISELISQYKSHGFMDVLHDKWYKVVPCG
                     KRSFAVTETLQMGIKHFSGLFVLLCIGFGLSILTTIGEHIVYRLLLPRIKNKSKLQYW
                     LHTSQRFHRALNTSFVEEKQPCSKTKRVEKRSNMGPQQLMVWNTSNLSHDNQRKYIFN
                     DEEGQNQLGTQTHQDIPLPPRRRELPASLTTNGKADSLNVARNSVMQELSELEKQIQV
                     IRQELQLAVSRKTELEEYQRTNRTCES"
     exon            1388..1992
                     /gene="Grin3a"
                     /gene_synonym="6430537F04; A830097C19Rik; GluN3A;
                     mKIAA1973; NMDAR-L; NMDAR3A; NR3A"
                     /inference="alignment:Splign:2.1.0"
     exon            1993..3040
                     /gene="Grin3a"
                     /gene_synonym="6430537F04; A830097C19Rik; GluN3A;
                     mKIAA1973; NMDAR-L; NMDAR3A; NR3A"
                     /inference="alignment:Splign:2.1.0"
     exon            3041..3186
                     /gene="Grin3a"
                     /gene_synonym="6430537F04; A830097C19Rik; GluN3A;
                     mKIAA1973; NMDAR-L; NMDAR3A; NR3A"
                     /inference="alignment:Splign:2.1.0"
     exon            3187..3302
                     /gene="Grin3a"
                     /gene_synonym="6430537F04; A830097C19Rik; GluN3A;
                     mKIAA1973; NMDAR-L; NMDAR3A; NR3A"
                     /inference="alignment:Splign:2.1.0"
     exon            3303..3454
                     /gene="Grin3a"
                     /gene_synonym="6430537F04; A830097C19Rik; GluN3A;
                     mKIAA1973; NMDAR-L; NMDAR3A; NR3A"
                     /inference="alignment:Splign:2.1.0"
     exon            3455..3619
                     /gene="Grin3a"
                     /gene_synonym="6430537F04; A830097C19Rik; GluN3A;
                     mKIAA1973; NMDAR-L; NMDAR3A; NR3A"
                     /inference="alignment:Splign:2.1.0"
     exon            3620..3696
                     /gene="Grin3a"
                     /gene_synonym="6430537F04; A830097C19Rik; GluN3A;
                     mKIAA1973; NMDAR-L; NMDAR3A; NR3A"
                     /inference="alignment:Splign:2.1.0"
     exon            3697..7651
                     /gene="Grin3a"
                     /gene_synonym="6430537F04; A830097C19Rik; GluN3A;
                     mKIAA1973; NMDAR-L; NMDAR3A; NR3A"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7627..7632
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Grin3a"
                     /gene_synonym="6430537F04; A830097C19Rik; GluN3A;
                     mKIAA1973; NMDAR-L; NMDAR3A; NR3A"
                     /note="hexamer: AATAAA"
     polyA_site      7651
                     /gene="Grin3a"
                     /gene_synonym="6430537F04; A830097C19Rik; GluN3A;
                     mKIAA1973; NMDAR-L; NMDAR3A; NR3A"
                     /note="major polyA site"
ORIGIN      
        1 agaacagaac cacccttcgc tggccagttg tgtcgctcct ccaaggaagc cgcggaagtg
       61 gcgcctgggc gaaaagcccg gcagaaaaag gaagagagga agtagaaagg gaagagggga
      121 aaatgaacca ggcgctgggg gagcccgcgg taaggtggcc ggcggggaaa ggaagcaggt
      181 tcggcagctg cttttccgca ccccgtgcgt gaacgccctc tcctctgcca ccccagtaaa
      241 taagtgggtg tctcctgaac tgaacagcaa gagaaaagaa gccagccaag tgagagtaca
      301 gctcctctgt cactgccgcc cccttgcaag tctggcggct tctcgcgggg ccagacgctg
      361 cgccccaggc gccctgcaga tggggtggac agggacccgg agctcaagcc acgggtgacc
      421 cgcgctggcc aaccggcctg cggcgcttgc ggaggatgct aggcggagga gccctggaac
      481 cgcatccgac actgcccggc gtccgctagg ctgcaacttg gaatgcccag ggagcggtcc
      541 ggctcctgtg accacttcgc cgcgtctagg gaagctgcgc tcaggatttg gaggcagaga
      601 cctcaggcgg cggagacctc cggcggcggc tgcagaggga agagccgggc gcaggagggg
      661 gcgcgctttc tcccagcggg tctcagtaat gaggagactg agtttgtggt ggctgctgag
      721 cagggtctgt ctgttgctgc ctccgccctg tgcactggtg ctggccgggg tgcccagctc
      781 ctcctcgcac ccgcaaccct gccagatcct caagcgcatc ggacacgcgg tgagggtggg
      841 cgcggtgcac ttgcaaccct ggaccacggc cccacgcgca gccagtcgcg ctcaggacgg
      901 cggcagggcg ggtgcccaga gggatgagcc agagtcgggg acgtggcggc caccggcgcc
      961 ctcgcaaggc gcacgttggt tggggagcgc cctgcatggc cggggtccac ccggctcccg
     1021 caagctcggg gagggcgccg ggaccgagac cctgtggccg cgggatgccc tactgttcgc
     1081 tgtggaaaac ctgaaccgtg tggaagggct ccttccctac aacctgtctt tggaagtagt
     1141 gatggccatc gaggcgggcc tgggcgacct gccacttatg cctttctctt ccccaagctc
     1201 accgtggagc agtgaccctt tctcctttct gcagagcgtg tgccacaccg tagtggtaca
     1261 aggggtttca gcgctgctgg ccttccccca gagccagggc gaaatgatgg agctggactt
     1321 ggtcagttct gtcctgcaca tcccagtgct cagcatagtg cgccacgagt ttccgcggga
     1381 gagtcagaat cccctgcacc tacagctgag tttagaaaat tcactaagtt ctgatgctga
     1441 tgtcactgtc tcaatcctga ccatgaacaa ctggtacaat tttagcttgt tgctatgcca
     1501 ggaagactgg aatatcaccg acttcctact ccttacagag aataactcca agttccacct
     1561 cgagtctatc atcaacatca ctgctaacct gtcctccaca aaggaccttc taagtttcct
     1621 gcaggtccag ctggaaaaca ttaggaacag cacacccaca atggtgatgt ttggctgtga
     1681 catggggagc atccggcaga tatttgaaat gtccacacag tttgggctat cacctcctga
     1741 tcttcactgg gttttaggag actcacagaa tgtggaggag ctgaggacag aaggcctgcc
     1801 cttagggctc attgctcatg gaaaaaccac acagtctgtc tttgagtact atgttcagga
     1861 tgccatggag ttggttgcaa gagctgtagc cacagccacc atgatccagc cagaacttgc
     1921 tctccttccc agcacaatga actgcatgga tgtgaaaacc acaaatctca cttctggaca
     1981 atatttatca aggtttttag ccaacaccac tttcagaggt ctcagtggtt ccatcaaagt
     2041 aaagggatcc accatcgtca gctcagaaaa caactttttc atctggaact tgcagtatga
     2101 ccctatggga aagccaatgt ggactcgcct gggtagctgg caagggggaa ggattgtcat
     2161 ggactcggga atatggccag agcaggccca gaggcacaaa acccacttcc atcacccaaa
     2221 caagttacac ttgagagtgg tgacactgat tgaacatcca tttgttttca cgagagaagt
     2281 agatgatgaa ggcttatgcc ctgctggaca actctgtcta gaccctatga ctaatgactc
     2341 ttccatactg gatagcctgt ttagcagcct acatagcagt aatgatacag tgccaatcaa
     2401 gttcaagaag tgctgctatg ggtattgcat tgatctactg gaacagttag cagaagacat
     2461 gaactttgac tttgacctct atattgtagg ggatggaaag tatggagctt ggaaaaatgg
     2521 tcactggact gggctggttg gtgatctcct gagtggaaca gccaacatgg cagtcacttc
     2581 tttcagcatc aatactgcaa gaagccaagt gatagatttc accagccctt tcttctcaac
     2641 cagtttgggc atcttagtga ggactcgaga cacagcagct cccattggag ccttcatgtg
     2701 gccactccac tggaccatgt ggctggggat tttcgtggct ctacatatca ctgccatctt
     2761 cctcactctg tatgaatgga agagcccctt tggtatgact cctaaaggga ggaacagaaa
     2821 caaagtcttc tccttctcct cagccttgaa tgtctgctat gcccttctgt ttggcagaac
     2881 agcagccatc aaacccccta aatgctggac tggaagattt ctgatgaatc tttgggccat
     2941 tttctgtatg ttttgccttt ctacatacac agcgaacttg gctgctgtca tggtaggtga
     3001 gaagatctat gaagaacttt ctggaatcca tgaccctaag cttcatcatc cttctcaagg
     3061 ttttcgtttt ggaactgtcc gggaaagcag tgctgaggac tatgtacggc agagcttccc
     3121 agagatgcat gagtacatga gaaggtacaa tgtaccagcc acccctgatg gagtgcagta
     3181 cctgaagaat gatccagaga aactagatgc cttcatcatg gacaaagccc ttctggatta
     3241 tgaagtgtca atagatgctg actgcaagct tctgaccgta ggaaagccat ttgccattga
     3301 aggctatggc attggtctcc ctcccaactc tccgttgacc tctaacatat ctgagctcat
     3361 cagtcagtac aagtctcatg ggtttatgga tgtgcttcat gacaagtggt acaaggtggt
     3421 tccctgcgga aagagaagct ttgctgtcac tgagactttg caaatgggca tcaagcattt
     3481 ctctggactc ttcgtgctgc tgtgcatagg attcggtctc tccatcctga caaccattgg
     3541 tgaacacata gtgtacagac tgctgctacc acgaatcaaa aacaaatcca agctgcagta
     3601 ctggctgcac accagtcaga ggtttcacag agcattaaac acatcatttg tagaagaaaa
     3661 gcagccatgt tccaagacaa aacgtgtgga aaagaggtcc aacatgggac cccagcagct
     3721 catggtatgg aatacttcca atctgagtca cgacaaccaa cgaaaataca tctttaatga
     3781 tgaggaagga caaaaccagc tgggtaccca gacccatcag gacatccctc tccctccaag
     3841 gagaagagag ctccctgctt cactgaccac caatgggaaa gcagactccc tcaatgtagc
     3901 tcggaactcc gtgatgcagg aactctccga gttggagaag cagatccaag tgatccgcca
     3961 ggagctgcag ttggccgtaa gcaggaagac agagcttgag gagtatcaaa ggacgaaccg
     4021 gacttgtgaa tcctaggctg tgtctctgct ctcctttctc agccactggt actctgaggc
     4081 ccttgaggct ctttgtaaag ctcttttata tctattgaca aaggtgtggg gtctggcaaa
     4141 tgaagtgtgc tgttctcagc ctaagatgca gcagcagctc ttcccacaca cgcccccagg
     4201 tctccagggt agaaatcttt ccaacagtag gaacctagag ttagtcagga gtaaagtctg
     4261 tctaagggga tcggcaagct gccagacaac tctggctcct gtcaaccttt tcacctggtg
     4321 ccacaaaagt atttctgctt tttagccctt tctctgcacc tcaacaagag ataaaaaaaa
     4381 actgttgctc atacccgtat cttactgggt ttgtttttaa tattattaca aaatagaatg
     4441 atccagtgtt gcagatttga tacaactccc caatctagat ttgacctaac attctgaatg
     4501 aacagggtag gagccacaca aactgggaca gaaaagatac attaaaaaaa aataataatg
     4561 aagggagctc agaattcaca caggcaaggg ttgactggcc aagctggcac catgtgcttg
     4621 tgcagctctg gatctctgag cctcccctga ctaaccttga gtaggaacat gctgatggga
     4681 caccaacaaa gcacagggtg cttttaaaat aaagccctgg gccagaaagg caatgtggct
     4741 aaagaatgta ttgcactata cttctaatgg aactaatcat ctccaccata gtgtgtgcct
     4801 tctataaagg agaaagcagc aaggccatgt ccttagcagg aacctttgct agccacctag
     4861 tgaatgcctg taacagggtc tctgagctga ctctgtatta agggaaattc tgcacaccac
     4921 aggtgaggct tttttcagat cagtggccac ctcttttagt ctgaggaatc ccagaagcaa
     4981 ccagagacca tcataaatgt caaataccgg agtctaccct gcttcaccat ctcccaccct
     5041 tatactgtct ctgatgagtt atgctaagtt ctagtctgat tatcctcctg gttccattta
     5101 aggccctcag agatcaatgc aattagccta gcttcccctt tgtttaggca tcactttcta
     5161 gtcatataat tgcttggcac gaagaaaaga aacatgagct ctctagactt cctgtatgtt
     5221 cccaactgtt ggctagataa tcatctgagg ctatcattat agtgctgatg tccaagactt
     5281 aaccagaagg gatctgggag ggcctagagg tgggctcaga attctagtgc taggtaacac
     5341 cctaggacac accacagccc taacacacca gttattctca gagaagcact gctctggaag
     5401 tttggctacc tctaggcatg tgagaaggaa ggaaagccta ttgccttttc tccttttact
     5461 tcagcaccca gctactgact ggtttccata tccccaccct acaccagggt tccatttgga
     5521 agtatacctt gtttatcagt cagtgttgct taggttctca cttctccagt cattgtaatg
     5581 tctacaagga atgcacaatg gagtgctcag atcactaaaa ggagcatcag tggcccaatt
     5641 cctcttactt tgggacacac tgtccacact ccaccaagag ctacacagat tcccacataa
     5701 agatagtgcc ctaagttgta atcagaacac ttgagcaagg agttaaatgg aggagtaaac
     5761 ctgggagtgc aagaaagctc aagaaacact caaggggagg caggggggct ttaaaaacag
     5821 acttcagctt cacagattca acatttcact gagggaagcc ctgaaaacag gacaaagagc
     5881 tctgcagcat cctcatgccc tattacattc tcagcccagt gggcctcagc tgcctttggt
     5941 aggttccatc ccttagccat tcccacccat ctgtaacaat gatctgggag ctcggctcca
     6001 agcatccctg gttacctgtt cagcctgcaa ggccgatgta tagtgtacct caattcacac
     6061 gacagcgaca gccatgctcc tgccgtacat ggacatctgt tcaacgactc atatttcaac
     6121 tgtacccgag aggctagcta tttaagggaa cacagaggta aattcttttg taaagaatcc
     6181 ttttgtaatg caaaccaatt atccctgaag gtatctgttt tgtaagtttg gatttttgta
     6241 tatctggttt atcttaagct tctctactga ggcattctga gtagtggcca tcagagtctc
     6301 ctgcctgccc acagagcaga gaaccagtgc acgctcttaa gagaaactac ttggccaaac
     6361 tggccaagac gcagcaagca gcagcaggaa caaagcaggc ttactgctgt caacactgct
     6421 taaaatgctt tcatgtccta ggtaaagaaa aaacataatt gcttgtgaag cagtttcatg
     6481 ataaatagta aaaaaaaaaa aacaaaaaca aaaaaaaatt aatggtagta attgaacagt
     6541 gttttgcaat ttgtgaaaca gtgtgctgtg ttttgtacaa agatttcacg aaagggagag
     6601 tccttctaaa cctatattct gctccaccgc aactccctca cctatcctca ggctcacagt
     6661 ggaaatgtcc agggacaggg ctgttagaat gagctaaggg agactgtttt gcgtcctgag
     6721 tttctatttc attggatcag gaaatcatcc acttgccaac caggctccag tactgggaaa
     6781 catggaatgt ggcaaactgt cccacactcc aagccattct ccaagggggc ctggcacagt
     6841 aagcacttca agcatgaatt gggtaagctg gtttgtttga ctaggaaacg gttccacaga
     6901 gtatttgcca caagaggaga gtatccctcc agcaaataaa agcaagttag aacgggctgg
     6961 atagccaaag aggcagccat tcggacctag gaagttgggg tctgtagtat gcctggattt
     7021 tctattattc atgagatttg tacaaaccct ataccggaat ggatgcttcc cttccacctc
     7081 cctgaaatgt acgtggagcc actcagaaca caactgtatc actgaggtaa ctcctcagtg
     7141 ttgggtccat tacagccttg gagcaaagtt gaccaccacc ttgtgtggat caagaagaga
     7201 agaaactact ttggagtttt tgaaaaagca agccagaaaa tccactgagc cttcagcaga
     7261 aattcctttt ctagacatta aaaccactta acatccgtac tgtttgttat atatttctcc
     7321 cgaccctact ccccactcct gccaccaagc acatccggtc taggggttcc tcactctctt
     7381 tcatttagct gccagtcatt ttatgaaaat gaagtgcttc taagtatttc cttaaggtct
     7441 gtgaagagta tttgccctgc gtcttcattt ccgtgtgtgt gcaactgctc cgctccaaga
     7501 actgcaccgc tgtcttgtga gcatggcgtg aacaggctgt tttgctccag ccacttttct
     7561 tgtacaacta cggggatgga ctagatgtcc tctggtcttt tccatcttcg ctttctatga
     7621 ctgtggaata aatgttcaga cagaaacttc aaaaaaaaaa aaaaaaa
//
