LOCUS       NM_001363750           23957 bp    mRNA    linear   ROD 19-MAR-2025
DEFINITION  Mus musculus glutamate receptor, ionotropic, NMDA2B (epsilon 2)
            (Grin2b), transcript variant 2, mRNA.
ACCESSION   NM_001363750
VERSION     NM_001363750.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 23957)
  AUTHORS   Huikang,W., Shiya,C., Di,P., Kiani,F.A., Hao,L., Sha,N., Xuan,L.,
            Abouelfetouh,M.M., Ahmed,Z., Mingxing,D. and Yi,D.
  TITLE     Elucidation of Dexmedetomidine-Induced Analgesic Tolerance
            Mechanisms in Neuropathic Pain With Modulation of SGK1, NR2A, and
            NR2B Expression via the Spinal SGK1/NF-kappaB Signalling Pathway
  JOURNAL   J Cell Mol Med 29 (6), e70372 (2025)
   PUBMED   40099662
REFERENCE   2  (bases 1 to 23957)
  AUTHORS   Candelas Serra,M., Kuchtiak,V., Kubik-Zahorodna,A., Kysilov,B.,
            Fili,K., Hrcka Krausova,B., Abramova,V., Dobrovolski,M., Harant,K.,
            Bozikova,P., Cerny,J., Prochazka,J., Kasparek,P., Sedlacek,R.,
            Balik,A., Smejkalova,T. and Vyklicky,L.
  TITLE     Characterization of Mice Carrying a Neurodevelopmental
            Disease-Associated GluN2B(L825V) Variant
  JOURNAL   J Neurosci 44 (31), e2291232024 (2024)
   PUBMED   38926089
  REMARK    GeneRIF: Characterization of Mice Carrying a Neurodevelopmental
            Disease-Associated GluN2B(L825V) Variant.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 23957)
  AUTHORS   Keith,R.E., Wild,G.A., Keith,M.J., Chen,D., Pack,S. and Dumas,T.C.
  TITLE     Individual NMDA receptor GluN2 subunit signaling domains
            differentially regulate the postnatal maturation of hippocampal
            excitatory synaptic transmission and plasticity but not dendritic
            morphology
  JOURNAL   Synapse 78 (4), e22292 (2024)
   PUBMED   38813758
  REMARK    GeneRIF: Individual NMDA receptor GluN2 subunit signaling domains
            differentially regulate the postnatal maturation of hippocampal
            excitatory synaptic transmission and plasticity but not dendritic
            morphology.
REFERENCE   4  (bases 1 to 23957)
  AUTHORS   Matsumoto,Y., Miwa,H., Katayama,K.I., Watanabe,A., Yamada,K.,
            Ito,T., Nakagawa,S. and Aruga,J.
  TITLE     Slitrk4 is required for the development of inhibitory neurons in
            the fear memory circuit of the lateral amygdala
  JOURNAL   Front Mol Neurosci 17, 1386924 (2024)
   PUBMED   38736483
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 23957)
  AUTHORS   Kaizuka,T., Hirouchi,T., Saneyoshi,T., Shirafuji,T., Collins,M.O.,
            Grant,S.G.N., Hayashi,Y. and Takumi,T.
  TITLE     FAM81A is a postsynaptic protein that regulates the condensation of
            postsynaptic proteins via liquid-liquid phase separation
  JOURNAL   PLoS Biol 22 (3), e3002006 (2024)
   PUBMED   38452102
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 23957)
  AUTHORS   Watanabe,M., Mishina,M. and Inoue,Y.
  TITLE     Distinct distributions of five NMDA receptor channel subunit mRNAs
            in the brainstem
  JOURNAL   J Comp Neurol 343 (4), 520-531 (1994)
   PUBMED   7518475
REFERENCE   7  (bases 1 to 23957)
  AUTHORS   Watanabe,M., Mishina,M. and Inoue,Y.
  TITLE     Distinct spatiotemporal expressions of five NMDA receptor channel
            subunit mRNAs in the cerebellum
  JOURNAL   J Comp Neurol 343 (4), 513-519 (1994)
   PUBMED   7518474
REFERENCE   8  (bases 1 to 23957)
  AUTHORS   Watanabe,M., Mishina,M. and Inoue,Y.
  TITLE     Differential distributions of the NMDA receptor channel subunit
            mRNAs in the mouse retina
  JOURNAL   Brain Res 634 (2), 328-332 (1994)
   PUBMED   7510577
REFERENCE   9  (bases 1 to 23957)
  AUTHORS   Watanabe,M., Inoue,Y., Sakimura,K. and Mishina,M.
  TITLE     Developmental changes in distribution of NMDA receptor channel
            subunit mRNAs
  JOURNAL   Neuroreport 3 (12), 1138-1140 (1992)
   PUBMED   1493227
REFERENCE   10 (bases 1 to 23957)
  AUTHORS   Kutsuwada,T., Kashiwabuchi,N., Mori,H., Sakimura,K., Kushiya,E.,
            Araki,K., Meguro,H., Masaki,H., Kumanishi,T., Arakawa,M. et al.
  TITLE     Molecular diversity of the NMDA receptor channel
  JOURNAL   Nature 358 (6381), 36-41 (1992)
   PUBMED   1377365
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC124500.5, AC132119.2, AC124590.4 and AC161364.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660815.255864.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-73                AC124500.5         69571-69643
            74-146              AC124500.5         70179-70251
            147-613             AC124500.5         71234-71700
            614-1042            AC132119.2         35178-35606
            1043-1641           AC124590.4         17345-17943
            1642-1756           AC124590.4         97613-97727
            1757-1959           AC124590.4         160479-160681
            1960-2131           AC124590.4         161418-161589
            2132-2285           AC124590.4         162001-162154
            2286-2411           AC124590.4         165907-166032
            2412-2641           AC124590.4         168393-168622
            2642-2802           AC161364.4         163504-163664       c
            2803-2990           AC161364.4         161541-161728       c
            2991-3229           AC161364.4         158866-159104       c
            3230-23957          AC161364.4         135803-156530       c
FEATURES             Location/Qualifiers
     source          1..23957
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 66.38 cM"
     gene            1..23957
                     /gene="Grin2b"
                     /gene_synonym="GluN2B; GluRepsilon2; Nmdar2b; NR2B"
                     /note="glutamate receptor, ionotropic, NMDA2B (epsilon 2)"
                     /db_xref="GeneID:14812"
                     /db_xref="MGI:MGI:95821"
     exon            1..73
                     /gene="Grin2b"
                     /gene_synonym="GluN2B; GluRepsilon2; Nmdar2b; NR2B"
                     /inference="alignment:Splign:2.1.0"
     exon            74..146
                     /gene="Grin2b"
                     /gene_synonym="GluN2B; GluRepsilon2; Nmdar2b; NR2B"
                     /inference="alignment:Splign:2.1.0"
     exon            147..613
                     /gene="Grin2b"
                     /gene_synonym="GluN2B; GluRepsilon2; Nmdar2b; NR2B"
                     /inference="alignment:Splign:2.1.0"
     exon            614..1042
                     /gene="Grin2b"
                     /gene_synonym="GluN2B; GluRepsilon2; Nmdar2b; NR2B"
                     /inference="alignment:Splign:2.1.0"
     CDS             632..5080
                     /gene="Grin2b"
                     /gene_synonym="GluN2B; GluRepsilon2; Nmdar2b; NR2B"
                     /note="glutamate [NMDA] receptor subunit epsilon-2;
                     N-methyl D-aspartate receptor subtype 2B; glutamate
                     receptor ionotropic, NMDA 2B"
                     /codon_start=1
                     /product="glutamate receptor ionotropic, NMDA 2B
                     precursor"
                     /protein_id="NP_001350679.1"
                     /db_xref="CCDS:CCDS20648.1"
                     /db_xref="GeneID:14812"
                     /db_xref="MGI:MGI:95821"
                     /translation="MKPSAECCSPKFWLVLAVLAVSGSKARSQKSAPSIGIAVILVGT
                     SDEVAIKDAHEKDDFHHLSVVPRVELVAMNETDPKSIITRICDLMSDRKIQGVVFADD
                     TDQEAIAQILDFISAQTLTPILGIHGGSSMIMADKDESSMFFQFGPSIEQQASVMLNI
                     MEEYDWYIFSIVTTYFPGYQDFVNKIRSTIENSFVGWELEEVLLLDMSLDDGDSKIQN
                     QLKKLQSPIILLYCTKEEATYIFEVANSVGLTGYGYTWIVPSLVAGDTDTVPSEFPTG
                     LISVSYDEWDYGLPARVRDGIAIITTAASDMLSEHSFIPEPKSSCYNTHEKRIYQSNM
                     LNRYLINVTFEGRNLSFSEDGYQMHPKLVIILLNKERKWERVGKWKDKSLQMKYYVWP
                     RMCPETEEQEDDHLSIVTLEEAPFVIVESVDPLSGTCMRNTVPCQKRIISENKTDEEP
                     GYIKKCCKGFCIDILKKISKSVKFTYDLYLVTNGKHGKKINGTWNGMIGEVVMKRAYM
                     AVGSLTINEERSEVVDFSVPFIETGISVMVSRSNGTVSPSAFLEPFSADVWVMMFVML
                     LIVSAVAVFVFEYFSPVGYNRCLADGREPGGPSFTIGKAIWLLWGLVFNNSVPVQNPK
                     GTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEYVDQVSGLSDKKFQRPNDFSPPFR
                     FGTVPNGSTERNIRNNYAEMHAYMGKFNQRGVDDALLSLKTGKLDAFIYDAAVLNYMA
                     GRDEGCKLVTIGSGKVFASTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWLT
                     GICHNEKNEVMSSQLDIDNMAGVFYMLGAAMALSLITFICEHLFYWQFRHCFMGVCSG
                     KPGMVFSISRGIYSCIHGVAIEERQSVMNSPTATMNNTHSNILRLLRTAKNMANLSGV
                     NGSPQSALDFIRRESSVYDISEHRRSFTHSDCKSYNNPPCEENLFSDYISEVERTFGN
                     LQLKDSNVYQDHYHHHHRPHSIGSTSSIDGLYDCDNPPFTTQPRSISKKPLDIGLPSS
                     KHSQLSDLYGKFSFKSDRYSGHDDLIRSDVSDISTHTVTYGNIEGNAAKRRKQQYKDS
                     LKKRPASAKSRREFDEIELAYRRRPPRSPDHKRYFRDKEGLRDFYLDQFRTKENSPHW
                     EHVDLTDIYKERSDDFKRDSVSGGGPCTNRSHLKHGTGDKHGVVGGVPAPWEKNLTNV
                     DWEDRSGGNFCRSCPSKLHNYSSTVAGQNSGRQACIRCEACKKAGNLYDISEDNSLQE
                     LDQPAAPVAVSSNASTTKYPQSPTNSKAQKKNRNKLRRQHSYDTFVDLQKEEAALAPR
                     SVSLKDKGRFMDGSPYAHMFEMPAGESSFANKSSVTTAGHHHNNPGSGYMLSKSLYPD
                     RVTQNPFIPTFGDDQCLLHGSKSYFFRQPTVAGASKTRPDFRALVTNKPVVSALHGAV
                     PGRFQKDICIGNQSNPCVPNNKNPRAFNGSSNGHVYEKLSSIESDV"
     exon            1043..1641
                     /gene="Grin2b"
                     /gene_synonym="GluN2B; GluRepsilon2; Nmdar2b; NR2B"
                     /inference="alignment:Splign:2.1.0"
     exon            1642..1756
                     /gene="Grin2b"
                     /gene_synonym="GluN2B; GluRepsilon2; Nmdar2b; NR2B"
                     /inference="alignment:Splign:2.1.0"
     exon            1757..1959
                     /gene="Grin2b"
                     /gene_synonym="GluN2B; GluRepsilon2; Nmdar2b; NR2B"
                     /inference="alignment:Splign:2.1.0"
     exon            1960..2131
                     /gene="Grin2b"
                     /gene_synonym="GluN2B; GluRepsilon2; Nmdar2b; NR2B"
                     /inference="alignment:Splign:2.1.0"
     exon            2132..2285
                     /gene="Grin2b"
                     /gene_synonym="GluN2B; GluRepsilon2; Nmdar2b; NR2B"
                     /inference="alignment:Splign:2.1.0"
     exon            2286..2411
                     /gene="Grin2b"
                     /gene_synonym="GluN2B; GluRepsilon2; Nmdar2b; NR2B"
                     /inference="alignment:Splign:2.1.0"
     exon            2412..2641
                     /gene="Grin2b"
                     /gene_synonym="GluN2B; GluRepsilon2; Nmdar2b; NR2B"
                     /inference="alignment:Splign:2.1.0"
     exon            2642..2802
                     /gene="Grin2b"
                     /gene_synonym="GluN2B; GluRepsilon2; Nmdar2b; NR2B"
                     /inference="alignment:Splign:2.1.0"
     exon            2803..2990
                     /gene="Grin2b"
                     /gene_synonym="GluN2B; GluRepsilon2; Nmdar2b; NR2B"
                     /inference="alignment:Splign:2.1.0"
     exon            2991..3229
                     /gene="Grin2b"
                     /gene_synonym="GluN2B; GluRepsilon2; Nmdar2b; NR2B"
                     /inference="alignment:Splign:2.1.0"
     exon            3230..23957
                     /gene="Grin2b"
                     /gene_synonym="GluN2B; GluRepsilon2; Nmdar2b; NR2B"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      23921
                     /gene="Grin2b"
                     /gene_synonym="GluN2B; GluRepsilon2; Nmdar2b; NR2B"
                     /note="major polyA site"
ORIGIN      
        1 ggagagcaag aggacgcgcg tgcacacaca ccctgcctct tgggtttctc ctcctgaacc
       61 tcctgtgtga gaggaaagaa aacgtctcaa accctcgaca cccgccaccc ctctccggag
      121 actgccacct cggaggtgca gaaccggaag gggacgcttt gggaatgacc acgctccacg
      181 gagggacaga gcctgccccc agcttctcca cacagagact cctctactaa agctccaaaa
      241 aattaaaaag aaaaagagaa aagaaaaaag aaaagagaac ccaaccctta attgccggag
      301 actccttaaa tctatatatt cgggctacta acctcacatg cacatggaat aatggctctg
      361 gattctgcat tgtgagccgc tctccacacc ctgagattcc ctttcacatt acattttttc
      421 ctttgaattt acatctcttc aagacacaag attaaaacca aattcacact ccactggatt
      481 ttaaatgttc ttctgtccct ttatcctccg tctttcttat gtggatatgc aagcgagaag
      541 aggactctgg atattcccaa catgcgctct cccttaatct gtccgcctag agctttggct
      601 tctacaaacc aagagagtcg acgagctgaa gatgaagccc agcgcagagt gctgttctcc
      661 caagttctgg ttggtgttgg ccgtcttggc cgtatcgggc agcaaagctc gttcccaaaa
      721 gagcgccccc agcatcggca tcgctgtcat cctcgtgggc acttccgacg aagtggccat
      781 aaaagatgcc cacgagaaag atgacttcca tcatctctca gtagttcccc gggtggagct
      841 ggtagccatg aacgagactg acccaaagag cataatcacc cgcatctgcg atcttatgtc
      901 tgaccggaag atccaggggg tggtgttcgc ggatgacacg gaccaggaag ccatcgccca
      961 gatcctcgat ttcatttctg ctcagactct cacccccatc ctgggcatcc atgggggctc
     1021 atctatgata atggcagata aggatgagtc ctccatgttc ttccagtttg gcccatccat
     1081 tgaacagcaa gcttctgtca tgctcaacat catggaagaa tacgactggt acatcttctc
     1141 catcgtcacc acctacttcc ccggctacca ggacttcgtg aacaagatcc gcagcactat
     1201 tgagaacagc tttgtgggct gggagctcga ggaagtcctc ctgctagaca tgtctctaga
     1261 cgatggcgac tctaagatcc agaatcagct gaagaagctg cagagcccca tcattctcct
     1321 ctactgcaca aaggaagaag ccacctacat cttcgaagta gctaactcag ttgggctgac
     1381 tggctacggc tacacatgga tcgtgccgag tctggtggcg ggggatacgg acacggtgcc
     1441 ttcagagttc cccacggggc tcatctctgt gtcatatgac gaatgggact atggccttcc
     1501 tgccagagtg agagatggga ttgccatcat caccactgct gcctcggaca tgctgtccga
     1561 acacagtttc atccctgagc ccaagagcag ttgctacaac acccacgaga agaggatcta
     1621 ccagtctaac atgctgaata ggtatctgat caacgtcact tttgaaggga gaaacctgtc
     1681 cttcagtgaa gatggctacc agatgcatcc gaagctggtg ataatccttc tgaacaagga
     1741 gaggaagtgg gagagggtgg gaaaatggaa agacaagtcc ctgcagatga aatactatgt
     1801 gtggcctcga atgtgtcctg agactgaaga acaggaagat gaccatctga gcatcgttac
     1861 cttggaggag gcaccgtttg tcattgtgga aagtgtggac cctctcagtg ggacctgcat
     1921 gcggaataca gtcccgtgcc agaagcgcat catctctgag aataaaacag atgaggaacc
     1981 aggctacatc aaaaaatgct gcaaggggtt ttgtattgat atccttaaga aaatttctaa
     2041 gtctgtgaag ttcacctatg acctttacct ggtgaccaat ggcaagcatg gaaagaaaat
     2101 caacgggacc tggaacggca tgattggtga ggtggtcatg aagagggcct atatggcagt
     2161 gggatcacta actatcaatg aagaacggtc agaggtggtt gacttctctg tgcccttcat
     2221 agagactggc atcagtgtca tggtatcacg cagcaatggg actgtgtcac cttctgcctt
     2281 cttagagcca ttcagtgctg acgtgtgggt gatgatgttt gtgatgctgc tcattgtctc
     2341 tgctgtagct gtctttgtct ttgaatactt cagccctgtg ggttacaacc ggtgcctagc
     2401 tgatggcaga gagccaggcg gcccatcttt caccatcggc aaagcgattt ggttactctg
     2461 gggtctggtg tttaacaact ccgtacctgt gcagaaccca aaggggacca cctccaagat
     2521 catggtgtca gtgtgggcct tctttgctgt cattttcctg gccagctaca ctgccaactt
     2581 agccgccttc atgatccaag aggagtatgt ggaccaggtt tccggcctga gtgacaagaa
     2641 gttccagaga cctaatgact tctcaccccc tttccgcttt gggactgtgc ccaatggcag
     2701 cacagagagg aatatccgta ataactatgc agaaatgcat gcctacatgg gaaagttcaa
     2761 ccaaaggggt gtagatgatg ccttgctctc cctgaaaaca gggaaacttg atgcattcat
     2821 ctacgatgca gccgtgctca actacatggc tggaagagac gaaggctgca agctggtgac
     2881 cattggcagt ggcaaggtct ttgcttctac gggctatggc attgctatcc aaaaagactc
     2941 tggttggaaa cgccaggtgg accttgctat cctgcagctg tttggagatg gggagatgga
     3001 agaactggaa gctctctggc tcactggcat ttgccacaat gagaagaatg aggttatgag
     3061 cagccagctg gacattgaca acatggcggg cgtcttctat atgttggggg cagccatggc
     3121 tctcagcctc atcaccttca tctgtgaaca tctcttctat tggcagttcc gacattgctt
     3181 catgggtgtc tgttctggca agcctggcat ggtcttctcc atcagcagag gtatctacag
     3241 ctgtatccac ggagtagcta tagaggagcg ccaatccgtg atgaactccc ccactgccac
     3301 catgaacaac acacactcca atatcctacg cttgctccga acggccaaaa acatggccaa
     3361 cctgtctgga gtcaacggct ccccccagag tgccctggac ttcatccgcc gtgagtcctc
     3421 tgtctatgac atctctgagc atcgccgcag cttcacgcat tcagactgca agtcgtacaa
     3481 taacccaccc tgtgaggaaa acctgttcag tgactacatt agtgaggtag agagaacatt
     3541 tggcaacctg cagctgaagg acagcaatgt gtaccaagac cactatcacc atcaccaccg
     3601 gccccacagc atcggcagca ccagctccat tgatgggctc tatgactgtg acaacccacc
     3661 ctttaccacc cagcccaggt caatcagcaa gaaacccctg gacattggcc tgccctcctc
     3721 caaacacagc cagctcagcg acctgtacgg caagttctct ttcaagagtg accgctacag
     3781 tggccatgat gacttgattc gatcagatgt ctcagacatc tccacgcata ctgtcaccta
     3841 tggcaacatc gagggcaacg cagccaagag gaggaagcag caatataagg acagtctaaa
     3901 gaagcggcca gcctcggcca aatctaggag ggagtttgat gaaatcgagc tggcctaccg
     3961 tcgccgacca ccccgctccc cagaccacaa gcgctacttc agggacaaag aagggctccg
     4021 agacttctac ctggaccagt tccgaacaaa ggagaactcg cctcactggg agcacgtgga
     4081 cttgactgac atttacaaag aacgtagtga tgacttcaag cgagattcgg tcagtggagg
     4141 cgggccctgt accaacaggt ctcaccttaa acacggaaca ggcgataagc acggagtggt
     4201 aggcggggtg cctgctcctt gggagaagaa cctgaccaat gtggattggg aggataggtc
     4261 tgggggcaac ttctgccgca gctgtccctc caagctgcac aattactcct ctacggtggc
     4321 agggcaaaac tcgggccggc aggcctgcat caggtgtgag gcctgcaaga aggctggcaa
     4381 cctgtatgac atcagcgagg acaactccct gcaggaactg gaccagcctg ctgcccctgt
     4441 ggctgtgtca tccaacgcct ccaccaccaa gtatcctcaa agcccgacta attccaaggc
     4501 ccagaagaag aatcggaaca aactgcgccg gcagcactcc tacgacacct tcgtggacct
     4561 gcagaaggag gaggccgcct tggccccacg cagcgtgagc ctgaaagaca agggccgatt
     4621 catggatggg agcccctacg cccatatgtt tgagatgcca gctggtgaga gctcctttgc
     4681 caacaagtcc tcagtgacca ctgccggaca ccatcacaac aatcccggca gcggctacat
     4741 gctcagcaag tcgctctacc ctgaccgggt cacgcaaaac cctttcatcc ccacttttgg
     4801 ggatgatcag tgcttgcttc acggcagcaa atcctacttc ttcaggcagc ccacggtggc
     4861 aggggcgtcg aaaacaaggc cggacttccg ggcccttgtc accaataagc cagtggtgtc
     4921 agcccttcat ggggctgtgc caggtcgttt ccagaaggac atttgtatag ggaaccagtc
     4981 caacccctgt gtgcctaaca acaaaaaccc cagggctttc aatggctcca gcaatggaca
     5041 tgtttatgag aaactttcta gtattgagtc tgatgtctga gtgagggaag agagagagag
     5101 agagagatta agatgggtgc gggagggata gggctgtggg ccgcgtggtg cgcatgtcac
     5161 ggaaagagtc gggggtgaac ttggctccca ttcgcttttt cttcttcttt taatttctct
     5221 atgggatcct ggagttctgg ttccttactg aaggcaaccc tcgtggccag caccctttct
     5281 cctcccttgc gcagttctct tcttcccgcg tctgtccacc attcctgttc ccataagagg
     5341 atagaacggg cctcagtgtg ggaggctgga gaggagacca gaagcgctgc ctgtgtgctt
     5401 cttcctagcg cagaagggct ctgagcgatt cactttgagc gaggctttcc tgatactgct
     5461 ctttttgttc aggcaaggaa gcgaaggtgt ttatctaagg aaggccattg aacctcctgc
     5521 tcctaagaga gaagaggctt tctctgaatt cttgctgcat ggttggcatc tgctgagggg
     5581 ccatgtgcca agcagagggc aggaagtcgt tgtatatata taagccaaaa agataataat
     5641 aataataaaa actttcttca gcttcagaag cctcaggggt ggtgaaccaa gggagaagcc
     5701 attggtagaa gagagattcc tgaacgaagt gggtagttca ctgctacagt gtcccatggt
     5761 gcattggaag caagagtatg ggactgtgta tgcacatata catgtacacc tgcactcaca
     5821 cgtagtcagg tgcctctgaa tacagagaac gaaacctcga ctggctgctt cctcccacat
     5881 acgaaagcaa tgcgcttttt tttttttttt tggcttatat ataaactgat gtcaccccaa
     5941 tttgggctat ctctccattt tttccttctt gagtgaaggt atagagattc ttgatgaaga
     6001 cgaatccata ttgcagaaaa gacaacagaa ggaaatgaat ggaactgagt caaccctaca
     6061 gaatactttg tcagtagctg ctaatgcttt ccaccagctt gggcagagag agcttttcag
     6121 taaggctgaa gggaaatgga aatagctgtg agtcctttac tcatacttag aatctaggca
     6181 ttcagcccct tagctggatg aggttttggg gaaagctctt cgtataaggc tttgtgaaag
     6241 agccattaca gtagggtgag agagggggat gtttttagtc attaacggta gggttagtga
     6301 gaaaggggga tgttttcaat gctttgatcc cttcttactt aacctagaac tgaaagggca
     6361 agcaaattcc ccctggattg gtgatgtgtc aaggggacac gtgggggaga gaaatgagct
     6421 catcgccaag ggtacatccc tggaaagcca gagagcatga aggattgaga agtgggagcc
     6481 tgggtcccta ggcatgtgac ttgaaatagt gcaagcgctt cgacaagccc cagttccctc
     6541 tcagattgta ccactcgaca gtgaatgtgc ttgcgtgcct gcgtgtgcgt gtgtgtgtgt
     6601 gcgtgtgcgt gtgcgtgtgc gtgtgcttgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt
     6661 gtgtgtgtgt aaaactacag ggatgggggt gctggcaggt gtgatgcccc ctcacttaaa
     6721 gttggaaaat taagaaggga aatgaatatt tgtcactgcc cgacctgaaa cttggggtag
     6781 gggtgttcca tgggtcagtt ctgctgccct gccctcccct cacacagggt ggcgtccaaa
     6841 gagccctggg tctgtgtgga agcttgactg caggatcgcc gtgtggcaca caggacacat
     6901 aaaccagaaa ggtgcttatt cttctctgga acgaagctgc catgtctctt cacgtcacat
     6961 cctcctggcc tgcttcttgc cttcctggtc gccccgcctc atggcctccc ctcatcccca
     7021 tactcgactg ctgtctccca ccttcctcct tgatttcttt ttaatttttt tttacctcag
     7081 tatctctcat ttaaatgcca actgaaggcc ttgttttctt tctaaaatga acgtgggggc
     7141 aaggggctga acctctcaac accctggaga gaggagcgcg gagtgcttta ttttaggttc
     7201 caggaaagac tctgagagag gacagagggc gtgaggcgtc tcccagagga agaaggagaa
     7261 gggccataga aacattgctt cactctggct ctgtccaagg gccagaggct catcccccac
     7321 tcttcctctt acctctcacc ctttaaaatt ttaaaaagaa aaaaaaaaag gaaaaaaaaa
     7381 aaagaaaaaa ccaaaccaac taacctagcg aacagcaatc tagaaaacag ggggctctgg
     7441 tggtctccac aggccacaga aatcaagatg gtgtttattt ggtatgtaaa tattttgttt
     7501 tctaattaat tttgtataga taaagtgttc tcctgtgagt attcagggtg ttgagccgga
     7561 gggagtgggg tggggatggg attgaggggg gattgtttcg ttatgggttt tcattttcag
     7621 ttggggaaat tgtttgacat ggcctttgtt tcagagtgtc tgggaaaaaa aaagttaacg
     7681 ggaacagaag ccactatggt gactaagcca ggggaaagcc atttatgtcc atgccccatc
     7741 tctgaaacct gtcttcctgc ggatctgtga gaagtgagca cgcactttac ctgagttttg
     7801 ctgggtctct atcagtatta agcaaaactt ggtctgactc ttgtcttcta gggagaccat
     7861 aggaaaccat caatctgtca aaaacaagct ggtggcatca gatttttctc tgtcagtacc
     7921 taggcttaca aaggttcccc aaaagggctt gaaaaagaat tgaggtccag cggcctcctt
     7981 tcttggcatg gctgagaggt ttcaggaagc caggttccga ggaatctcac agcagccttc
     8041 tctgatactc aacaatcatc ttaccattct gatccttcat gctctggtac ccgagctcgg
     8101 agcgccccat ccgtctacct gtgcctccct gtagaaatga cctcttcggg cacacccaag
     8161 aaatctccac taattttact taagcatgtg gtttcaggct ggtagaggga tagcaatgga
     8221 tacaagggtc ttacagacat atatgctttt ctagaaaagg tccccagact ccctcaaaac
     8281 tagcaagata gctaaaacta gttatagagg tgggcaagtg ggtatgtgag ggacagtatc
     8341 aatggtggct taagagttac cttgttcttg ttactgccat taggaaggtg ctattttgct
     8401 caaatcaggt gtcccaaatc tgatttgggg ctaaccagac aaatagaatc tcttttactg
     8461 gattgttggc tttgtgaaag atagcagctt ctctctcccc tcccccatcc tccccccccc
     8521 cattcctaaa ttgatatacc caacatactg cattttctcc cctattctct taccatcaga
     8581 gactgtcatc tgggaaattt aactatccta aaccccttat ttggcctcaa ttgatcattt
     8641 tttttcacct ggatactgga gttgggacca aagtacggtc ttcatggcct actctagaat
     8701 gaataagaaa atgaagtctg tcaagttata gatgtaaaat tccatcataa caagccagta
     8761 ggatgcctaa gaattcagca gtggctccca tctccatccc tgatggatac ggaccaagat
     8821 ccaatccatc caaaactgtg aggttctgta gagccctgag agcaccttat gttccacagt
     8881 gtccttcaga atccatgctc tctctcatga gtgctagctt cccctgcggg agtgggtgga
     8941 tgggtgtggt cctgcatcac tccttttagt ggcaatgctg acccattcgc atgcccagtg
     9001 acctcaacaa cctgaccctt gaatttgcct gaagtgaaga tgtgcacacc ctctcggagt
     9061 gtggcatgta cagtggacct tgttatttcc aagctgtcac tgtgtatcct caaccagcac
     9121 ttgggaaacg tccctaatgt gtgttccctg gtactggcca cagccatttt gtgattgggg
     9181 caaaactccc agatgatccc attaaatgtt ggtggtgtca gtagtgccca aacgcatgtg
     9241 taaaatagga gtcttctata cagtgatgtg agtaccactc acccagtctt ccatggccat
     9301 caggaattgc cccagggaga attctctgca gagtgctggt cacctgcacc tctcatttaa
     9361 gagctagggt ttcttttgtt tggtttggtt tttgtttgtt tgtttttttt ttcagtaact
     9421 tgaagattta gggaaagatt aactataata tttgggcaaa agcctttgga aaagctattc
     9481 ctgaactcaa attgtcatta ttttttttat ttatttttat ttttttgatc accgtctctg
     9541 aaaaggccct gtccttactt ggcaccctgt gagtgtctgt tttggtgtgc taggaatgat
     9601 tcatgtgtgc gcatacatga tgtaatggca gtttattggt gaatgtgttt ggtgtttctg
     9661 ggcattgtgg ccatatggta tgttcccaaa gccatataga aattgtggga tctaggggcc
     9721 gcgaaaacac atggcgtcac ctttgctttc ttcaccttgg tgtcagagaa tgttcttgct
     9781 gtctaaggga ttctttaggg caagaggcac cccaaggagg tcagtcatac cagagtggct
     9841 ctagccttac caaaggcaaa tgacccatgg ctcgctttca agatcccaga agagcctgcc
     9901 aactgctggc ttcccagaca gatttactac actagggccg agctgtccat ctgctgttga
     9961 aatgaaagtg ttcccaggaa gagtgacata ctaagccata ttagggattt gtacatttaa
    10021 acacctaatc tacattagga ttttcattcc ttttcctggg gataaactct aataagccag
    10081 caggagaagg caagtagagc atcatgaacc tcagagcagg gagaaagaat aaagggtccc
    10141 gaaaactagt cagtgaagcc atgcctcatc tctacctgtt tagttaaggc ccatgggaac
    10201 ctggcttagg agttctacat gggcgttgat tcttcaacac acactcatgt acatagttta
    10261 taaacagcag aatttaacac catgtagagc aggtaagaac tgtgacttgg gaagcaaaag
    10321 acagacacct ctcctcaaat acaagatagt gaagagaaag ccgtaaagaa aaacggtcat
    10381 tcacatttag tacataaccc attagtatac tgtaggaatc actgaagaat ctgttctctg
    10441 ttcctgatca aatgatcggc cactcaattg tcttgcctgc attctaaact tttctagtct
    10501 ccttccccat attccctgtg aaggagccaa ttgaccctcg ggtgctattt aacctgtggg
    10561 cctatgatat ggttgagtcc atgctacagt gtacatttgt cattctgaag gcttctagta
    10621 ttgatctggg tctaggattc catctgactt gaggaggcag ccatctataa ggtcacaggc
    10681 agaatggtac atcctgctgc catcccgttc taaccacatt ttctcagtca tatcccgtct
    10741 ctgtgagttc tgtggcttgg aatattacct ctctactcca acaacaaagc cccagccaaa
    10801 gccttaagtg aaagtctgtg cttttataat gccttggaga gagctctagg tagtagtaca
    10861 gaagcaaagg gaagtaactt tgctttgaga gtattgggtt accatagtga tgcctgggat
    10921 acagaacatt aggaatctgt gcatcactct gccactgtgt ccttgggcat tgatatcaga
    10981 gttaataatt gtgagctgct ggtgatggcc cacattttgc atttgctggt gtgactgggg
    11041 gggggctgtt aatgggaact gagagtggaa agtagagtga acggtagagt tcctcacagc
    11101 cttgggatgc tgccgtagag catatggatt ttggcaaaag tgaaagtggt atttagtgca
    11161 agggtcagag ttacaatcta agtccattac aaaactgtta ttttaaagat atggcttcta
    11221 acctgagctc tatttgtcag ttaataatca tcttacagtt gtgatttaaa gggtagtaaa
    11281 gaaaaaaatc aattaaaaag tcctacataa atatgtaact taaaataagc caatgtttgt
    11341 tgagcattta ttatgaccct gagctggtgc tgagaagcat ataaaagttt ttaaaatgga
    11401 gtatgttatg ttcatgcagg ctgtgcaaat gcacaaatgt tagctattta catgtatgta
    11461 ttgtgtctat ataaataggt gtgcataaag tcctctcatt atacatgaag gtttaatatt
    11521 ttctggtgtc agggtttgtg tcaaagatat ccatcatgtt atttaagaat accacaaaga
    11581 ttcaacattt ctacatcaag gccaagccct cgtcacttct tctgggatta caacccattc
    11641 tagagctaaa ttctcagaga ttcccttaga tcacagcctt gaaattcctc actcatctct
    11701 gccagtttct cagctgaaca ctcttcatcc ctgtgcacca acccctgccc ttgagacctt
    11761 cttgaggtac acttcaggct tctccatgtt gcatttttac tcccttccac ccagctgact
    11821 atattcatct caaaacaaaa cttggaaacc aactgtagga tcaaatcttc tctccgtttg
    11881 attagattct tgaatgccca tttttaatct ctgtttgttc ttgctctccc ggccttctca
    11941 attggatagt ctttctttac atccacaccc aatgtggaca ttggtgtcca catagacacg
    12001 gctttgcaat gagtctataa tctgctactc acctacaaac accgaacagc aatatttcaa
    12061 tgagcatctt gctacaaaac ccaccggtct ttcttttgct ctgctgctca tgtgtagaca
    12121 ttaacctgag ctaagcatca agaggtggtc cattctgatg tgcatcttag ctctcaggtc
    12181 ctcggtgagc ttgctgcttc ctgattctgc tcaaccttga cttggcgtgt attctaaggt
    12241 tgactctctc tatcttaact cctcaaaatc tttctgactc ctataacgtt catggttctg
    12301 agtgaattca agtcttcact cctagaccct aattttctct tcagctcagt actgaatctc
    12361 accttacatt gactcaaata cccagattgg ccccttcaaa ccaacataat tagaaagtct
    12421 ccttctggct gatggtacca ctggtctctc accacactaa ggttttgcca agaatttttg
    12481 cctctctcat gtccccagtt ttgcacatgt aatcatttgg aaagcctgtt ggttctcact
    12541 ctagagttgg tttggcctct gttgctcctc ctaactcttc ccttcattga tggtttcagt
    12601 gttgtacatc attgtttgaa gagtttatat ttcagtctac tctcatcagc ttgcctgtcc
    12661 taacgacagc tagtacacat cctccctagt cccagaaaca agtttaatga gccaccctgg
    12721 ccatggtttt ccaacaagca ggactgatgg ccatgttccc ttgtgttgtc cttgtggcag
    12781 gacagttaaa ttacaaactt gtcccttact ctttagccag ctagattggc ttgtatctta
    12841 aactactctt ttccccaaat tccctacttc caactctcct caccctcctc tcttacagaa
    12901 tccacttctt ctgtttaaat cttcaaaaac aacgacaaac aactatagca tatattcccc
    12961 ttcacaagct ctgcacaaaa aatctaggca atttatgaat gtccatgaca tgcaattata
    13021 tctcctggat ggcacccaac agagaccacc ctcataatga tttggttgtg tgtgctatct
    13081 tccccacacc agattctgaa caagccatac atttagtagt ctattgtttc ctatattacc
    13141 taattgggtg tcttgtatat gaagaacact agtgaatatt tgatattata aataacaatg
    13201 gaaaatgagt tcacttattt tacccacaga atatttgaat ctacaggaat atgtaaggat
    13261 gagttcttgc cccacaaact ccacgtttct ctttttctcc acacagagcc tcagtagtac
    13321 actcacagca tgtgtgtgca tttccacagg cttatttcca gtggaaatgt gtatttctcc
    13381 aagtcatgct tcattctctg aagtccttct tctttggcta cttcatggtt attaatgtgt
    13441 ctctgcagtg atggttgtgc acaaaataaa tgtcagaaga ttagacttcg aagaatgttg
    13501 atcaaatggg aggtgagtag agctgatgtc gggacatgtc actgtcctga gtgagcacag
    13561 tatgatctat gctgggattg acaggtcttt gtttcaagag ttagacagtt tgagttattt
    13621 ggacccttgt tacaagataa gctcactaac cactcagctt tgtgagtctc aataggattt
    13681 gtgatccaat aggattgcac tgagtgctgg aagttgccac ctttgtaacc aggtggccca
    13741 gacccggggt caggggctat ttgttctgct tctccccttg gcttgatgac tttcttttct
    13801 tgccctttct gaggctttat ggcactgagg ttattaaaca cattacctct gacatgcaca
    13861 tctcaagtga gaacacgtca gaattttaat gacttgatcc agaagaattc tagtgtctca
    13921 attcctcttt tctttagatg tgattagatt cgttgcccta gaggagagtg tagcaccact
    13981 ggcctgatga tcctcttgtt gctctgtctt cctgcagcct ttgctgttgg tccctcagtt
    14041 ttactgaaca attccaccta ttcattctag ttactgtcca tttctgtctc tgaaagaact
    14101 cttggggcta gtcctatact tttacttaat cttctctggt accaggtaat attctctttc
    14161 tttctcctgc ccagcttccc ctataaatct catgatgtca ttggtcatga attattctcc
    14221 tttgggaggc atcttctgcc actgagtgct aatttaaagc atactggagt gaacctaact
    14281 caaataagtt acaggcaatg acaagtctgt ttttcaaaaa acctagcagg gttcattctt
    14341 catcaagaca ggaaggggtc gagagattat tattggcaag ctggagtgaa acttgtgaca
    14401 ccttaggagg aatctagtaa aagttaaaat gttaagtcta aaggggtagg gtttattttt
    14461 gtcagttcta atagatgtag ataatattaa tcctagcaat ggggataatt aacattttaa
    14521 agtagagtcc atcttatgat attatgagac tggttttaag cagaggaaca gtctggtact
    14581 aactagtggc tgtggggaca gacagctgtt ctctcaaaga cgggcatttc tgctggacca
    14641 gtggatgtgt caacaaactg catgaagttt tccatgatta ttttctattg tcttattcta
    14701 ctctttgtaa gaaattattt accagtacct gtaaagggta aataataaga ggcccataat
    14761 agttctaacc ttcacatcac aagtagaact gagagcctga tggtccctga tttgaggttc
    14821 ccttcaggaa gtaaggaacc cccaaaggac cagacttgcc catagcccat tcctttggcc
    14881 acagctaatt ttcgaaacct cacgttaaca ggagagcatg attccaggag tctcccaaag
    14941 gagggaagaa ttctcctttc tgtttacctc ttttggttgt aacctgagag gcaaaaggga
    15001 gacagattcg atctagggta tattacaaag cattttctaa tggcccattt caaagtactt
    15061 ggggacttta ggctgtgtga gccattgttg aaatgccagg ggaggtatcc agagagaact
    15121 ctgtacctga ggtaagggag ctggactcag ccttatcctt gaggttctag atgcttacag
    15181 gaagtctggt cacttgtcat ccctgagtca ttgccctagt cctttggatg acacccagag
    15241 agttgttgct caccaccctg ggcacagaga gcacagcttg tcctaccatc cttgctgtag
    15301 aatgctaacc tttgcaaatc tgtctacctt ggcaggagca ggttcacagt attggctctg
    15361 acaggggagg agctgcaggg gctgtgatca cagtgatgtg aaagcgcaca ggggcctgct
    15421 tccttaagat gatggtactg cttagctcca aagggattcg tttctccttt taaaacaaaa
    15481 cgaaacaaca aaacaaagta ctatgccttt ctgatacctc agccctagtc agactagttt
    15541 gtgtagcagt cattgccgca ttttaattct aattagttaa ttgtagtcaa ttattatcaa
    15601 taatcatttt cttttgcaat tagagctatt ttaatgtttc gacgtggtat aagaaacatt
    15661 agcaagccac agctgatgcc accttgttgt ctctgtctga attgtacttt cagtcttaca
    15721 aataggttcc atgtccttct catagttgca tgtaattaga tgatcacttt gctatgagta
    15781 ctttcatgtt tgtgtatttt accactgccc ctcaaacaca cacacacaca cacacacaca
    15841 cacacaaaca caattaggat aaaaagctaa gaacattaat gtgtacatga tatttaatgc
    15901 tcctaaacaa gagcctgacc agtatagttc tgttaacccc cccactttgt cctttgatgc
    15961 ccaagacgta aataacaagg catcttgaac cagaggaaat aatcatttta tcacagtcct
    16021 cgagactctt gggcatttta aatgactagg gcaatgagtt cagctattga gttatttgag
    16081 ttcagtcttg ataaacggca aaagaaatca ctaagacatg ggatagttta ccatcaccat
    16141 ttctccagac aacctccttg gacatggaaa cgtaatggag tttagttata cagatgaaca
    16201 cgctgaagta caaatgcatt ggtaagtcaa agcttgcata gtgcattgtc tggattttgt
    16261 accacagtct gtctcagaaa atcatgcggc atgtataact ctcctactcc aagtttctaa
    16321 taccaaacaa cagagggaag ccatgaaatc caggcagttg ttttaaccaa acctttcaca
    16381 caaaattcat cttcccagat ttccaccctg cccacttccc ataatccatt agtctataga
    16441 agccagtcaa tgagtggagc aaagcgggca tctgaaaaac agagacagaa aattttctgt
    16501 aatgaaggaa atttgaagag caaatcaaga tgtatggatc ttgtgaggtt agacatggag
    16561 aataactttc attattcaaa attttcttat ggaatgtgat cagaccaaac ctcccagatt
    16621 agtagcctag gaagggaact attaagaata tgtgtgaggt ggtaatgaaa tgctgaaggt
    16681 gtcagtagtt tgggctagcc cacagggata gctacttcaa aggagaatca tttacattat
    16741 tccctgggtc attgtatcta atgtagccac atttaagcat attcgactac taatattaag
    16801 gcacaagttg gttttggaaa cattatgtac atgaagtata gtgcaactag catgtgcaag
    16861 gaactcctga caaaagacct gctgtccccc ggagccagaa taaatgattg acttcctaaa
    16921 tcctaaagga aggggagtag taatgtctgc agcaagtcgt catgagactt ttttttcacc
    16981 ccaagattat aatggtaaat tgtttaataa tcataactga aggtctcccc ccatagctac
    17041 cttctctggt tcctcattcc catgcatggg aagaggaagt gaggccagca taggaatgct
    17101 cctcacactg aaagtttaga attaagttgg tgacaaatag cacttctctt cccccttgtt
    17161 tgcctcctgc ttcctggcat aagaacatgt tggtatgcat agcaaactaa gaaaaggggc
    17221 agcccattta ttttaccttg atgccacagt ggctttgtca ttcttatgag ttgcattacc
    17281 tatgtcatga tgctccctac tagcagatat caaggccaag atctgacggg tgttggagca
    17341 tttgagtccc ctgagatggc cattttctct ttggtgctat tctcatattc attgtcggtt
    17401 agaatggaaa gaggattcgt aggaccctaa gggcatggct ggagaattac ttaattgaaa
    17461 ccacaaagcc cctgtgctta atattaaata ttaaagtgga aatgaaaaag gcaaccctcg
    17521 agcccagctg cccacagtac agatcagaga agcattatgg gaaaagtctt agaaagaaag
    17581 tccctatcta accaaggcca aagcagccaa actgaaaata taaaagaatc acagtagctt
    17641 cctattgtga gggtgttatg gctggcacag attgttcctg tgctaagata gaaacaggta
    17701 aaagtccatc tcagagccta gggctctctc ctcagcagca gtgtgtgcat gaacctaaac
    17761 tccttgccgc tgaccttggg gacagaacgg aattcctctc atattgcaga ttgatttttt
    17821 tcctaagccc agcttaccca ctggtcattg agccctgggg taagttataa ccttccctta
    17881 gcctcctgtc atctaccact tctattgaag agcaatcctg aaaacctgtt tggttttaag
    17941 gcctgctgga tgaagctaga tatctgggtg gaggttggaa atgggcaacg tgtttcaaca
    18001 ccaagaagag aggccccctg tgcaaatgtg catgcccagt aacttgtaat ctaatcagaa
    18061 agtccgaaag gcttttgtag gttcgaggca tctttatttc aatggaacaa gatggcatat
    18121 tcctattctc ttcgtcttca gctcactgcc tgggatacca aatgtgcttc ttcccagaga
    18181 gatagaccag accaagacca aaagccaaac atccccaggc agctgtgact gccctctgcc
    18241 tatctttgtt tctttcccca tattacctgc cacatgataa aaacaaaaaa tctgcacagt
    18301 catcaccaat caaacaccat actagcaaaa tacaatacag aaatttagta agaaatagtg
    18361 aaaccagggg ccggagagag agctcagtgg ttaagatcac tggctcctga gttcaattcc
    18421 cagcaaccac atggtggccc atgaccatct atgataggga tttgatgccc tcatctggca
    18481 tgcaggcaca tatgcagata caaatagaca taaaataaat aattaaacaa caacaacaac
    18541 aaacgagtaa aatcagtgtg tttcactaaa tcccagtcat ctttggggaa tataattctg
    18601 tctgtctata atccatccct cctctgaaga ccttcccctt aaaagccatt attacaacat
    18661 gaatggtagc tatgctagga aattggcccc cataatactt attttatagc cactgaaaag
    18721 tgggttttat agttgacaat agcttttcca gttcttccca cagggaaatc tgtctttccc
    18781 tccctgcctc ttgccatagc tcctgatacc acttcttgat gcggctctcc ctctctacct
    18841 tgttctcctg ttagcaaaga atgccctcct ttaactgagt tcttatttag acagtctgct
    18901 tggaaaatga tctgagagta atttctcatt ggctttctcg ttactcttta atttgaaaag
    18961 gagttgaaag gaaatagtaa gaaagcaggc aaaccaggcc tcgtcctcaa acgcttcaac
    19021 tcaaggtcga gtgcccagaa agtgagtgtc ctcaagtggg agcctgagga cgtgtaaagg
    19081 agagagctgt gctcccgaat attaagcagc cactgagcag gtgcacatgg gctttggtca
    19141 agatgatttc tgtgcgcatg gacacattaa tctcttgccc cagctctggt ttcctgcaac
    19201 gctggctcct tttctctgtc atttcaaggc cccggatctg tgcatggaga gtgtttgttt
    19261 tcatttgagc acactgatga tggtacgctc gctccagctc tgccctgagt atagaggaag
    19321 ccaatgcttt ttaaatcctt ctaccaatga gctgttgcat gtcaggtacg agctgtttag
    19381 aatatattaa aatgagaggg aaaaaaagat agatgagaaa taaattcagc gacaagtaga
    19441 acagagcgtg gttttgaaat aatgttcttc accaagctga gaaaaaagtc cagaagcaaa
    19501 agaaaggggg ttgaatagtt tggaagacaa aagagggtaa tattcacacc aagacactct
    19561 ggttatcccc actaaaaaat agtctttcac ccccaagccc tcatgagctc tatcggaagg
    19621 agaagcctgc tactgctggc tgctggtgat tgctcagaca tggaggtgga ctgactttag
    19681 aaacagtctc agactttttt acagaaaggt accgataaac aatacaccct gagtcttcaa
    19741 gactcatcta cagacctcag gaccactccc cactagccgt ctccattctc cagtctagaa
    19801 tattctgagg agaaaagcca catgatcatt gtagctgcaa ttactcattt tgagaagcca
    19861 aagggcacag aggagaggtg aatatatcaa gagtacagag ctagttcacc ctttttaatt
    19921 tcttcatctt cttcaagttc agcgtggctt gccatcacaa acttaggtca atcacatctt
    19981 cccaccccag tgaaaacacc aagttttata atctgattac tgtttactcc agaaaggaaa
    20041 ttggtggatt caattacaaa caggcatttt acagattgcc ttaatcctga ttcttacaca
    20101 tagtaacatg gaatgcattg actcagacct gatctcctaa gctgtaaaac ctcactgaag
    20161 ggaaatagat catgtgtttc tgaaccaact ttgttaaaag tatgaagtaa tgctcgagaa
    20221 tgttctatct gctaattcta caattagcag aaggcgtttg gaaagtaggc aacacgggac
    20281 aagcagagaa aaggatggag acagagtcca accaactaat gagaaattaa ggttattttt
    20341 aattattaaa aataataata aacccagcat caattcttag attccaaatg agctctgtgt
    20401 ttgtcacgcc aatgtttgca taagtaacag agatccaggg tttcatttta tttattttct
    20461 tggaagaggc gctttagtgg tcgtttgttt tactttactt ttctatgaaa ctggacttgg
    20521 aaagcatttg tttgcagctt gaggacatgt ttatccttgt aaggttgctt atgcaattga
    20581 aaccctattc caggacagtc taggtgctgg gaatgagcac accagtgttt ctgtctcttg
    20641 agcctcgtgt gtcactgaaa ggaaatcttt catatgttgt agtaacctta agatgcttag
    20701 cagacattca ggtggaaagc agattaggcc aagcttgacg ttgaggtccc cagggaagtt
    20761 tttgttttgt ttggtttgtt tgtttgtttg tttgtttgtt tgttttttga aatggcccat
    20821 tttgtgatgg ccagaatgat ccagtagaga gaagaaattg atagttccta gaaagagaag
    20881 atgctgatgg gtaatatcta tgatgagctt aagggaatgg aatccaatgc acaaacagaa
    20941 ggctggatgt aggtgcctgc aggccattta taatggaaag actatggtat tggtcacaga
    21001 tgcaagtagg tagatagatt gggggttctg tctgttttga ttgatgattc ttcagtgaca
    21061 tgcaaaagga gctcataagt taaggggcta cccaggatgg tttcaaggac caaaccaggc
    21121 agaggagaac agcgaggatt gcctgatgca cttgactcta gatttggtca ctgtgttgtt
    21181 ttaagggaga gaggtggaat ggtctgagaa tggcagtgag gagcaagcga gccacctcta
    21241 gactggtgcc aggacagatg tgtgtcagga gagcacacta ctcagtgaga ctgccggagc
    21301 ctcaaggatg agccaggaag gtggcagcaa tcgtcaggga atgtatggca gtggaggacc
    21361 ccaattaaca ggaaggaatg ggagttagga gggatggaag atgggcccac ctaggagatg
    21421 aacacgctca cccatggatg aaggtcagag cgggttcctc acagtgactc tcctgagcca
    21481 agctatgggc agctaaagtt ggtactggtc gtctttatca gactgaagtg gcagggctgc
    21541 ccgggctaga ctaggcctca ccagcaacgt gtggcacctg taatggtcca tcaccacccc
    21601 cacaccccac acctgctttt taattgctcc taaaatgtct acccccacat tctacttttg
    21661 cttatttact tgattggaga caaagtccaa tcctcctgcc tcagcctcca gagagctgga
    21721 attacatgca tcaatgtcca ctcctggttt ggctgtgcct cttgtcacag atgtctttag
    21781 atatgagcct gaatgcaaac tgcacagtga ctcttcactt ccagaaagat catacccaac
    21841 tgtcaacctt accctttctc ctttaaaatc ttccaactaa agttgctctc cttggggggg
    21901 gggggggaat cagaattctt tgttcttact tatcttagtc tttgttcatc ttttaaaaga
    21961 aatctcagag aatagcgaac agctttgctt ctgcccaacc ctggcaagtg aaggtttcct
    22021 ctgactggtc atttttatcc ggtgtttcct tttgtggcag agaacaatag gccaggagca
    22081 ttaggaagtg attggacatc tctaaaagct ctgcagggag ggcatttcgg atgattagga
    22141 tgactggtta gggaggacgg gttttgagtg aggctgaatg agggggaggg ggagggggag
    22201 ggggagggga gggggagaag tattttgaag ataatactgg aaaaaataag tttgaccaaa
    22261 ggagatggca gagggtaggg ttgggggacc cactttgtag cacctggaga tttagcaagc
    22321 ataaactcga tcctgccttc cccacacact catgtctggc tccaatgacc aactggtctt
    22381 atttcattta atgggccttt aggaaatcat aatttgaaga gacagtaggc atttctagtt
    22441 ctcctgaccc aacagaatct cgaacagggg accggggata tcataagggc agtggctggt
    22501 tcagcatcac tgttcaccag ggaacatgta cccttcacct ctgtcttatc cttcctgatg
    22561 gtcctctcaa agattagctg gtgttcaccc aggctcatct aatgcctgtc ttcagttctg
    22621 cgttggaata gtattacagc caactcaagg gcttattcca tgctttgtgc accaatgctg
    22681 gctagagctc ctttagcaaa gaataggaaa gccagagcta ctggggtatg tgttgactgc
    22741 tttacttcct gcccagcagg aatccagcct ttcaaaggta aactgagcac agcctagttt
    22801 ccatctactg agacttccct tgctttagga ggtcacacca acataattgg gcaagaagaa
    22861 gtatggaatc tgtgtcaagt gggggagagg ttgacaaagg agaagaaatt ttaagtggga
    22921 gttttgtgac ccattgacca cccccgcact cataccttag agttagccct tgcatttgtg
    22981 gaaacacatc ctgggagcta gctggcatga tagcatggga ccagagacga cacgggatag
    23041 gacaatgaac tcttacctgt aggaaatatc tcttttcttc cagtgctcca acgatgtgtc
    23101 ataagtacac tgagccacaa tggccgaagc atgtgcgtgt gtgcctgtgg gtgtgtgtgt
    23161 gtgagtttga gcaggagtgt gaagggctga tggtggaaac acagaacaca cccacggtgg
    23221 cttgggctgc agtctcagaa ccacagccct gcaggagtca ttcctgggga ggggtaatgg
    23281 tcatagcttc ccgggtgtgg tgttccccgg caccggaagc actcaggctt gcctggactc
    23341 tgtgaggcca gataccacat tcctcccctg ggccagcctt ccttcctctt gactctcaga
    23401 tccccccagg ccattcactt ccaagttctt ttaggtttgt ttgtttcggt tttttgtttt
    23461 ggttttctgt aaatatcgat ttcttatttt ggacatgcag ggatcaattg agattctgga
    23521 gtggggggag gggcggatga ctgggtcttt tatttttttt ctttctctct tggattttgg
    23581 tgtttgaact tgaaaaaaaa atacaagtat atatataagc aaatgactta cctttaacaa
    23641 tcgaaataag ttgatttcat tcttttgttt tatcttgttt ctcattgggg tagggtgggg
    23701 gtgggggggt ctctcgggtg gagggctttt ttgtgagctg tatagatttc cagtttggac
    23761 ttgttcaaat gatgcaggaa caaaaattaa aatgagttaa aaaaaaagac aacataaaaa
    23821 caagaaaaac ctttgtgatg tataaaagct gtacatagtc aaagatcctt tctcttttct
    23881 aatggcaaat tatttctgtc actttatatt caaaaaataa agaaacctac cacaaattat
    23941 cagggtaaaa aaaaatc
//
