LOCUS       NM_016886               5098 bp    mRNA    linear   ROD 11-MAR-2025
DEFINITION  Mus musculus glutamate receptor, ionotropic, AMPA3 (alpha 3)
            (Gria3), transcript variant 1, mRNA.
ACCESSION   NM_016886
VERSION     NM_016886.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5098)
  AUTHORS   Reinders,N.R., van der Spek,S.J.F., Klaassen,R.V., Koymans,K.J.,
            MacGillavry,H.D., Smit,A.B. and Kessels,H.W.
  TITLE     Amyloid-beta-Driven Synaptic Deficits Are Mediated by Synaptic
            Removal of GluA3-Containing AMPA Receptors
  JOURNAL   J Neurosci 45 (9), e0393242024 (2025)
   PUBMED   39779375
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5098)
  AUTHORS   Shigesawa,I., Nakamura,A., Yamauchi,Y., Kawata,S., Miyazaki,A.,
            Nomoto,H., Kameda,H., Terauchi,Y. and Atsumi,T.
  TITLE     Effects of glucokinase haploinsufficiency on the pancreatic
            beta-cell mass and function of long-term high-fat, high-sucrose
            diet-fed mice
  JOURNAL   J Diabetes Investig 15 (12), 1732-1742 (2024)
   PUBMED   39305123
REFERENCE   3  (bases 1 to 5098)
  AUTHORS   Eltokhi,A., Bertocchi,I., Rozov,A., Jensen,V., Borchardt,T.,
            Taylor,A., Proenca,C.C., Rawlins,J.N.P., Bannerman,D.M. and
            Sprengel,R.
  TITLE     Distinct effects of AMPAR subunit depletion on spatial memory
  JOURNAL   iScience 26 (11), 108116 (2023)
   PUBMED   37876813
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5098)
  AUTHORS   van der Spek,S.J.F., Pandya,N.J., Koopmans,F., Paliukhovich,I., van
            der Schors,R.C., Otten,M., Smit,A.B. and Li,K.W.
  TITLE     Expression and Interaction Proteomics of GluA1- and
            GluA3-Subunit-Containing AMPARs Reveal Distinct Protein Composition
  JOURNAL   Cells 11 (22), 3648 (2022)
   PUBMED   36429079
  REMARK    GeneRIF: Expression and Interaction Proteomics of GluA1- and
            GluA3-Subunit-Containing AMPARs Reveal Distinct Protein
            Composition.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5098)
  AUTHORS   Aruscavage,P.J. and Bass,B.L.
  TITLE     A phylogenetic analysis reveals an unusual sequence conservation
            within introns involved in RNA editing
  JOURNAL   RNA 6 (2), 257-269 (2000)
   PUBMED   10688364
REFERENCE   6  (bases 1 to 5098)
  AUTHORS   Kaczmarek,L., Kossut,M. and Skangiel-Kramska,J.
  TITLE     Glutamate receptors in cortical plasticity: molecular and cellular
            biology
  JOURNAL   Physiol Rev 77 (1), 217-255 (1997)
   PUBMED   9016303
  REMARK    Review article
REFERENCE   7  (bases 1 to 5098)
  AUTHORS   Zhang,C., Hammassaki-Britto,D.E., Britto,L.R. and Duvoisin,R.M.
  TITLE     Expression of glutamate receptor subunit genes during development
            of the mouse retina
  JOURNAL   Neuroreport 8 (1), 335-340 (1996)
   PUBMED   9051806
REFERENCE   8  (bases 1 to 5098)
  AUTHORS   Lomeli,H., Mosbacher,J., Melcher,T., Hoger,T., Geiger,J.R.,
            Kuner,T., Monyer,H., Higuchi,M., Bach,A. and Seeburg,P.H.
  TITLE     Control of kinetic properties of AMPA receptor channels by nuclear
            RNA editing
  JOURNAL   Science 266 (5191), 1709-1713 (1994)
   PUBMED   7992055
REFERENCE   9  (bases 1 to 5098)
  AUTHORS   Gregor,P., Reeves,R.H., Jabs,E.W., Yang,X., Dackowski,W.,
            Rochelle,J.M., Brown,R.H. Jr., Haines,J.L., O'Hara,B.F., Uhl,G.R.
            et al.
  TITLE     Chromosomal localization of glutamate receptor genes: relationship
            to familial amyotrophic lateral sclerosis and other neurological
            disorders of mice and humans
  JOURNAL   Proc Natl Acad Sci U S A 90 (7), 3053-3057 (1993)
   PUBMED   8464923
REFERENCE   10 (bases 1 to 5098)
  AUTHORS   Sommer,B., Kohler,M., Sprengel,R. and Seeburg,P.H.
  TITLE     RNA editing in brain controls a determinant of ion flow in
            glutamate-gated channels
  JOURNAL   Cell 67 (1), 11-19 (1991)
   PUBMED   1717158
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL672232.23 and AL672290.16.
            
            On Apr 17, 2020 this sequence version replaced NM_016886.4.
            
            Summary: This gene encodes a multi-pass transmembrane protein that
            forms a homotetramer or heterotetramer in neuronal cells. The
            encoded protein is a ligand-gated ion channel that responds to the
            neurotransmitter L-glutamate to promote synaptic transmission.
            Deficiency of this gene leads to behavioral phenotypes. The
            transcript is subject to RNA editing at codon 769 (AGA->GGA; R->G).
            Alternative splicing results in multiple transcript variants.
            [provided by RefSeq, Aug 2013].
            
            Transcript Variant: This variant (1) encodes isoform a. Both
            variants 1 and 2 encode isoform a.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC086678.1, AB022342.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            undergoes RNA editing  :: PMID: 10688364, 7992055
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-258               AL672232.23        8507-8764
            259-417             AL672232.23        9910-10068
            418-657             AL672232.23        85669-85908
            658-845             AL672232.23        148185-148372
            846-899             AL672232.23        176997-177050
            900-1061            AL672232.23        195573-195734
            1062-1229           AL672232.23        198819-198986
            1230-1334           AL672290.16        736-840
            1335-1442           AL672290.16        1673-1780
            1443-1649           AL672290.16        3508-3714
            1650-2026           AL672290.16        14968-15344
            2027-2225           AL672290.16        25851-26049
            2226-2473           AL672290.16        59060-59307
            2474-2588           AL672290.16        74555-74669
            2589-2836           AL672290.16        77273-77520
            2837-5098           AL672290.16        81394-83655
FEATURES             Location/Qualifiers
     source          1..5098
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 23.19 cM"
     gene            1..5098
                     /gene="Gria3"
                     /gene_synonym="2900064I19Rik; GluA3; Glur-3; GluR-C;
                     GluR-K3; Glur3; Gluralpha3"
                     /note="glutamate receptor, ionotropic, AMPA3 (alpha 3)"
                     /db_xref="GeneID:53623"
                     /db_xref="MGI:MGI:95810"
     exon            1..258
                     /gene="Gria3"
                     /gene_synonym="2900064I19Rik; GluA3; Glur-3; GluR-C;
                     GluR-K3; Glur3; Gluralpha3"
                     /inference="alignment:Splign:2.1.0"
     CDS             168..2834
                     /gene="Gria3"
                     /gene_synonym="2900064I19Rik; GluA3; Glur-3; GluR-C;
                     GluR-K3; Glur3; Gluralpha3"
                     /note="isoform a precursor is encoded by transcript
                     variant 1; glutamate receptor channel alpha3 subunit;
                     glutamate receptor 3; AMPA-selective glutamate receptor 3"
                     /codon_start=1
                     /product="glutamate receptor 3 isoform a precursor"
                     /protein_id="NP_058582.4"
                     /db_xref="CCDS:CCDS30097.1"
                     /db_xref="GeneID:53623"
                     /db_xref="MGI:MGI:95810"
                     /translation="MGQSVLRAVFFLVLGLLGHSHGGFPNTISIGGLFMRNTVQEHSA
                     FRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQM
                     SMNTLTSFCGALHTSFVTPSFPTDADVQFVIQMRPALKGAILSLLGYYKWEKFVYLYD
                     TERGFSILQAIMEAAVQNNWQVTARSVGNIKDIQEFRRIIEEMDRRQEKRYLIDCEVE
                     RINTILEQVVILGKHSRGYHYMLANLGFTDIVLERVMHGGANITGFQIVNNENPMVQQ
                     FIQRWVRLDEREFPEAKNAPLKYTSALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDC
                     LANPAVPWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGY
                     WNEYERFVPFSDQQISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCV
                     DLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLV
                     REEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFL
                     VSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSG
                     RIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTK
                     EFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQ
                     RKPCDTMKVGGNLDSKGYGVATPKGSALRTPVNLAVLKLSEQGILDKLKNKWWYDKGE
                     CGAKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAESKRMKLTKN
                     TQNFKPAPATNTQNYATYREGYNVYGTESVKI"
     exon            259..417
                     /gene="Gria3"
                     /gene_synonym="2900064I19Rik; GluA3; Glur-3; GluR-C;
                     GluR-K3; Glur3; Gluralpha3"
                     /inference="alignment:Splign:2.1.0"
     exon            418..657
                     /gene="Gria3"
                     /gene_synonym="2900064I19Rik; GluA3; Glur-3; GluR-C;
                     GluR-K3; Glur3; Gluralpha3"
                     /inference="alignment:Splign:2.1.0"
     exon            658..845
                     /gene="Gria3"
                     /gene_synonym="2900064I19Rik; GluA3; Glur-3; GluR-C;
                     GluR-K3; Glur3; Gluralpha3"
                     /inference="alignment:Splign:2.1.0"
     exon            846..899
                     /gene="Gria3"
                     /gene_synonym="2900064I19Rik; GluA3; Glur-3; GluR-C;
                     GluR-K3; Glur3; Gluralpha3"
                     /inference="alignment:Splign:2.1.0"
     exon            900..1061
                     /gene="Gria3"
                     /gene_synonym="2900064I19Rik; GluA3; Glur-3; GluR-C;
                     GluR-K3; Glur3; Gluralpha3"
                     /inference="alignment:Splign:2.1.0"
     exon            1062..1229
                     /gene="Gria3"
                     /gene_synonym="2900064I19Rik; GluA3; Glur-3; GluR-C;
                     GluR-K3; Glur3; Gluralpha3"
                     /inference="alignment:Splign:2.1.0"
     exon            1230..1334
                     /gene="Gria3"
                     /gene_synonym="2900064I19Rik; GluA3; Glur-3; GluR-C;
                     GluR-K3; Glur3; Gluralpha3"
                     /inference="alignment:Splign:2.1.0"
     exon            1335..1442
                     /gene="Gria3"
                     /gene_synonym="2900064I19Rik; GluA3; Glur-3; GluR-C;
                     GluR-K3; Glur3; Gluralpha3"
                     /inference="alignment:Splign:2.1.0"
     exon            1443..1649
                     /gene="Gria3"
                     /gene_synonym="2900064I19Rik; GluA3; Glur-3; GluR-C;
                     GluR-K3; Glur3; Gluralpha3"
                     /inference="alignment:Splign:2.1.0"
     exon            1650..2026
                     /gene="Gria3"
                     /gene_synonym="2900064I19Rik; GluA3; Glur-3; GluR-C;
                     GluR-K3; Glur3; Gluralpha3"
                     /inference="alignment:Splign:2.1.0"
     exon            2027..2225
                     /gene="Gria3"
                     /gene_synonym="2900064I19Rik; GluA3; Glur-3; GluR-C;
                     GluR-K3; Glur3; Gluralpha3"
                     /inference="alignment:Splign:2.1.0"
     exon            2226..2473
                     /gene="Gria3"
                     /gene_synonym="2900064I19Rik; GluA3; Glur-3; GluR-C;
                     GluR-K3; Glur3; Gluralpha3"
                     /inference="alignment:Splign:2.1.0"
     exon            2474..2588
                     /gene="Gria3"
                     /gene_synonym="2900064I19Rik; GluA3; Glur-3; GluR-C;
                     GluR-K3; Glur3; Gluralpha3"
                     /inference="alignment:Splign:2.1.0"
     exon            2589..2836
                     /gene="Gria3"
                     /gene_synonym="2900064I19Rik; GluA3; Glur-3; GluR-C;
                     GluR-K3; Glur3; Gluralpha3"
                     /inference="alignment:Splign:2.1.0"
     exon            2837..5098
                     /gene="Gria3"
                     /gene_synonym="2900064I19Rik; GluA3; Glur-3; GluR-C;
                     GluR-K3; Glur3; Gluralpha3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5078..5083
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gria3"
                     /gene_synonym="2900064I19Rik; GluA3; Glur-3; GluR-C;
                     GluR-K3; Glur3; Gluralpha3"
                     /note="hexamer: AATAAA"
     polyA_site      5098
                     /gene="Gria3"
                     /gene_synonym="2900064I19Rik; GluA3; Glur-3; GluR-C;
                     GluR-K3; Glur3; Gluralpha3"
                     /note="major polyA site"
ORIGIN      
        1 agtgtggggt ggaaaggaag agtgagcgag cgagagcaag ttgaggggag ggggtgtaag
       61 agccggcgaa ttctttttct ttttctatta ttattttgac gactcccgag ttgcgcccat
      121 gctcttgtca gcttcgtttt aggcgtagca cagccaggca gaagaaaatg gggcaaagcg
      181 tgctccgggc ggtcttcttt ttagtcctgg ggcttttggg tcattctcac ggaggattcc
      241 ccaacaccat cagcataggt ggacttttca tgagaaacac ggtacaggag cacagtgctt
      301 tccgctttgc tgtgcagtta tacaacacca accagaacac cactgagaag cccttccatt
      361 tgaactacca cgtagaccac ttggattcct ccaatagttt ttctgtgact aatgctttct
      421 gctcccagtt ctccagaggg gtgtatgcta tctttggatt ctatgaccag atgtcaatga
      481 acacactgac ctccttctgt ggggccctgc atacatcttt cgtcacacct agctttccca
      541 ctgatgccga tgtgcagttt gtcatccaga tgcgcccagc cttaaagggt gccattctga
      601 gtcttctggg ttactacaag tgggagaagt ttgtgtacct ctatgacaca gaacgagggt
      661 tttccatcct gcaagcaatt atggaagcag cagtgcaaaa caactggcaa gtgacagcaa
      721 ggtctgtggg aaacataaag gacatccagg aattcagacg catcattgaa gaaatggaca
      781 gaaggcagga aaaacgatac ttgattgact gtgaagtcga aaggattaac acaattttgg
      841 aacaggttgt gatcctgggg aaacattcaa gaggttatca ctacatgctt gctaacctgg
      901 gttttactga cattgtactg gaaagagtca tgcatggggg agccaacatt acaggtttcc
      961 agattgtcaa caatgaaaac ccaatggtcc agcaattcat acagcgctgg gtgagactgg
     1021 atgaaaggga attccctgaa gccaagaatg caccactaaa gtatacatct gcactgacac
     1081 acgacgcaat actggtcata gcagaagcct tccgatacct gaggaggcag cgagtggatg
     1141 tatcccgcag aggcagtgct ggagactgct tagcaaatcc tgctgtgccc tggagtcaag
     1201 gaattgatat tgagagagct ctgaaaatgg tgcaagtaca aggaatgact ggaaacatcc
     1261 aatttgacac ttatggacgt aggacaaatt ataccattga tgtatatgaa atgaaagtct
     1321 caggctctcg aaaagctggt tactggaatg agtatgaaag gtttgtgccc ttctcagatc
     1381 aacaaatcag caatgacagc tcatcctccg agaacaggac catcgtagtg actaccattc
     1441 tggaatcacc atatgtaatg tataaaaaga atcatgagca actggaagga aatgagcgct
     1501 atgaaggcta ttgtgtcgat ttagcctatg aaatagccaa acacgtaagg atcaaataca
     1561 aattgtccat tgtcggtgat gggaaatatg gcgcaaggga tccagagact aaaatatgga
     1621 atggcatggt tggggaactt gtctatggaa gagctgatat agctgttgct ccactcacta
     1681 taacattggt ccgtgaagaa gtcatagatt tttcaaagcc atttatgagc ctggggatct
     1741 ccatcatgat aaagaagcct cagaaatcaa agccaggcgt attttcattc ctggatcctt
     1801 tagcttatga aatctggatg tgcattgtct tcgcttacat tggagtcagt gtagttctct
     1861 tcctagtcag cagatttagc ccttatgagt ggcacttgga agacaacaat gaagaacctc
     1921 gtgacccaca aagccctcct gatcctccca atgaatttgg aatatttaac agtctttggt
     1981 tttccttggg tgcttttatg cagcaaggat gtgatatttc tccaagatca ctttctgggc
     2041 gcattgttgg aggggtttgg tggttcttca ccctgatcat aatctcttcc tacactgcaa
     2101 accttgctgc tttcctgact gtggagagga tggtgtcccc catagagagc gctgaagatt
     2161 tagccaagca gactgaaatt gcatacggga ccctggactc tggttcaaca aaagaatttt
     2221 tcagaagatc caaaattgct gtgtatgaga aaatgtggtc ttacatgaaa tccgcagagc
     2281 catctgtgtt taccaaaaca acagctgatg gggtagcccg agttcggaag tccaagggaa
     2341 agttcgcctt cctgctggag tcaaccatga atgagtacat tgagcagaga aagccgtgtg
     2401 atacgatgaa agttggtgga aatctggatt ccaaaggcta tggtgtggca acccctaaag
     2461 gctcagcatt aagaacgcct gtaaaccttg cagtattgaa actcagtgaa caaggcatct
     2521 tagacaagct gaaaaacaaa tggtggtacg ataaggggga atgtggagcc aaggactccg
     2581 ggagtaagga caagaccagt gctctaagcc tgagcaatgt ggcaggcgtg ttctatatac
     2641 ttgtcggagg tctggggctg gccatgatgg tggctttgat agaattctgt tacaaatcac
     2701 gggcagagtc caaacgcatg aaactcacaa agaacaccca aaactttaag cctgctcctg
     2761 ccaccaacac tcagaattac gctacataca gagaaggcta caacgtgtat ggaacagaaa
     2821 gtgttaagat ctagggatcc cttcccaccg gaagcatgca atgagaggaa atcactgaaa
     2881 acgtggctgc ttcaaggatc ctgagccaga tttcactctc cttggtgtcg ggcatgacac
     2941 gaatattgct gatggtgcaa tgacctttca ataggaaaaa ctgatttttt ttttccttca
     3001 gtgccttatg gaacactctg agacttgcga caatgcaaac catcattgaa atctttttgc
     3061 tttgcttgaa aaaaaattaa aataaaacca acaaaaaatg gacatgcaag attccagtat
     3121 gcgaaaaaaa ttcttattaa aaacattaat tcaacaaaag ccattctttg ataccactgc
     3181 acagtatacg aaaccatgtt cgttaacaca cacacaaaca cacacacaca cacacacaca
     3241 cacacactca cttatgtata cacattcaca catacaaatt tattctaatt cagcaaaata
     3301 gacccatctt agctaaaaga aataattcct cctgatttaa aataaaagaa atctgtctcc
     3361 cagtgttcgg gcagacagac tggcatttct tctaggatct gctgatcaga tgtttttggt
     3421 atttcctgtt ggtggtgatg ttctgtgcac cctatttcct tttgatgttg ctgaattgtg
     3481 taaatcttta gaatgtaaat gtgacactta agaaaattca aatgctttgg gaaagagact
     3541 gaatggtgac ttagtgttct tgcaatggtt ttgtgacaaa aaaaaaaatg tttggagaac
     3601 tccccatagt ggaggtgaag ggattaatag agcctttgaa attgacatct gtgtgtagca
     3661 tggggcaggg cactgtcagg cttacctctc ggtgctttcc taaaacggat cccggagctt
     3721 tccaagaagc ctggaattac agcccacaga tagatctgtt tttcttaatt ccgtgtgcat
     3781 tttaagtcaa tatagctgag tagttgaata gtaagcactg aggtgaggga agtgctgcct
     3841 attctcccag acgtgtttgg aatatctttc tcagaaacaa cactgtgttt agctctgctt
     3901 tctctgctaa gtatgcctaa gtgtacaaca cggagacaga accgtgttgc aaggcaggcc
     3961 agtgggttca gaccacagtt ctcaatctga ctttactctt gctaggtctg tttaaccagc
     4021 tgttgcctgt taccgcctgc ctgtggctct ccgtcagact gcatgtgtcc ttttctagtt
     4081 tgcaaagact aagacgcatt cctaaaccta ttgctaacct gagggaccta agcatcactc
     4141 ccaggtcctt gcttggagca gtttctctac tgaactgaag atcgccccac tgctccatgg
     4201 gctctcaagt aactaattgc aaacctgctg ttgacgtcat cagaccagtc agaggaaata
     4261 gtctccgctc actaattacc tcctatataa caatgtatgc tttctgtagt tcagtagtat
     4321 gctctcatca gtaacgtgca ttggaaagtt tccagactgt acaaattagg agcccacctt
     4381 catttcccaa gtgtgaccct tagatgctta gttgactcgc gcatatttgc tctcgtcttt
     4441 agaaaagaaa ggaagaggtc tcgttccaat gaaacatttc tagaaaggtg taatataaac
     4501 tttcattcca gaaagtgtgt cataagcaaa taactcacct gtcagatttt aaatggtatt
     4561 gaacacaaaa gaaagctgtt gtgttttgtt ttgttttcat gaaactgtga tttttcaact
     4621 tatgaatgct ataatgtccc agtgcgggaa gctaactctg tgtgaatatc aacttgtata
     4681 aaacaaacca actgacctat acacaaacat ttttcatagg cactgtataa agagaaatgt
     4741 atgtttattg actcaaatca gtttttcaga gaggaaactt tactgagatg aagaagcggg
     4801 taaattggtt tgttatttaa aaaaaaaaaa acttgcatgt ttaaaaaaat gttgattgct
     4861 tcaaatttct gctattaact tcaagctatg ggagtttggc ggtagtcaat tgaggatttt
     4921 tttccatttc ttttcttttt gttgttaaag ctgtacttca gtgaacagaa aaattgccaa
     4981 gcaaactaat ggccgtaaaa gtgtaaattg catgtgtggg cataattacc gaacctcatt
     5041 gccatgaggt atgtacaaag ttttaataca ttttgtaaat aaaattgtaa agaaagca
//
