LOCUS       NM_172768               7488 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus GRAM domain containing 1B (Gramd1b), transcript
            variant 1, mRNA.
ACCESSION   NM_172768
VERSION     NM_172768.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7488)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 7488)
  AUTHORS   Ferrari,A., Whang,E., Xiao,X., Kennelly,J.P., Romartinez-Alonso,B.,
            Mack,J.J., Weston,T., Chen,K., Kim,Y., Tol,M.J., Bideyan,L.,
            Nguyen,A., Gao,Y., Cui,L., Bedard,A.H., Sandhu,J., Lee,S.D.,
            Fairall,L., Williams,K.J., Song,W., Munguia,P., Russell,R.A.,
            Martin,M.G., Jung,M.E., Jiang,H., Schwabe,J.W.R., Young,S.G. and
            Tontonoz,P.
  TITLE     Aster-dependent nonvesicular transport facilitates dietary
            cholesterol uptake
  JOURNAL   Science 382 (6671), eadf0966 (2023)
   PUBMED   37943936
REFERENCE   3  (bases 1 to 7488)
  AUTHORS   Andersen,J.P., Zhang,J., Sun,H., Liu,X., Liu,J., Nie,J. and Shi,Y.
  TITLE     Aster-B coordinates with Arf1 to regulate mitochondrial cholesterol
            transport
  JOURNAL   Mol Metab 42, 101055 (2020)
   PUBMED   32738348
  REMARK    GeneRIF: Aster-B coordinates with Arf1 to regulate mitochondrial
            cholesterol transport.
REFERENCE   4  (bases 1 to 7488)
  AUTHORS   Ferrari,A., He,C., Kennelly,J.P., Sandhu,J., Xiao,X., Chi,X.,
            Jiang,H., Young,S.G. and Tontonoz,P.
  TITLE     Aster Proteins Regulate the Accessible Cholesterol Pool in the
            Plasma Membrane
  JOURNAL   Mol Cell Biol 40 (19), e00255-20 (2020)
   PUBMED   32719109
  REMARK    GeneRIF: Aster Proteins Regulate the Accessible Cholesterol Pool in
            the Plasma Membrane.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 7488)
  AUTHORS   Nakano,Y., Wiechert,S. and Banfi,B.
  TITLE     Overlapping Activities of Two Neuronal Splicing Factors Switch the
            GABA Effect from Excitatory to Inhibitory by Regulating REST
  JOURNAL   Cell Rep 27 (3), 860-871 (2019)
   PUBMED   30995482
REFERENCE   6  (bases 1 to 7488)
  AUTHORS   Pan,J., Mor,G., Ju,W., Zhong,J., Luo,X., Aldo,P.B., Zhong,M.,
            Yu,Y., Jenkins,E.C., Brown,W.T. and Zhong,N.
  TITLE     Viral Infection-Induced Differential Expression of LncRNAs
            Associated with Collagen in Mouse Placentas and Amniotic Sacs
  JOURNAL   Am J Reprod Immunol 74 (3), 237-257 (2015)
   PUBMED   26073538
REFERENCE   7  (bases 1 to 7488)
  AUTHORS   Bailey,P.J., Klos,J.M., Andersson,E., Karlen,M., Kallstrom,M.,
            Ponjavic,J., Muhr,J., Lenhard,B., Sandelin,A. and Ericson,J.
  TITLE     A global genomic transcriptional code associated with CNS-expressed
            genes
  JOURNAL   Exp Cell Res 312 (16), 3108-3119 (2006)
   PUBMED   16919269
REFERENCE   8  (bases 1 to 7488)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   9  (bases 1 to 7488)
  AUTHORS   Carlson,C.M., Dupuy,A.J., Fritz,S., Roberg-Perez,K.J.,
            Fletcher,C.F. and Largaespada,D.A.
  TITLE     Transposon mutagenesis of the mouse germline
  JOURNAL   Genetics 165 (1), 243-256 (2003)
   PUBMED   14504232
REFERENCE   10 (bases 1 to 7488)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK033156.1 and AC135353.3.
            
            On Nov 4, 2017 this sequence version replaced NM_172768.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK033156.1, SRR17253012.7052763.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2814              AK033156.1         1-2814
            2815-7488           AC135353.3         43142-47815
FEATURES             Location/Qualifiers
     source          1..7488
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 21.42 cM"
     gene            1..7488
                     /gene="Gramd1b"
                     /gene_synonym="3222402H23; A930008A22Rik; mKIAA1201"
                     /note="GRAM domain containing 1B"
                     /db_xref="GeneID:235283"
                     /db_xref="MGI:MGI:1925037"
     exon            1..471
                     /gene="Gramd1b"
                     /gene_synonym="3222402H23; A930008A22Rik; mKIAA1201"
                     /inference="alignment:Splign:2.1.0"
     CDS             95..2731
                     /gene="Gramd1b"
                     /gene_synonym="3222402H23; A930008A22Rik; mKIAA1201"
                     /note="isoform 1 is encoded by transcript variant 1; GRAM
                     domain-containing protein 1B; protein Aster-B"
                     /codon_start=1
                     /product="protein Aster-B isoform 1"
                     /protein_id="NP_766356.1"
                     /db_xref="CCDS:CCDS23081.1"
                     /db_xref="GeneID:235283"
                     /db_xref="MGI:MGI:1925037"
                     /translation="MPAANMMENLQLPALQVPEPQGAPEGSAVWSSSSTPTLRRRRFK
                     MRRMKNVQEQSLEAGLVAPDLPGVLAPGKEFLQLPSIEITPSSDEDTPWSNCSTPSAS
                     PRRKRFLLRKWLRVRERKECSESSSQQSSQQSSHDDDSSRFLSPRVRDESTASNSNRS
                     TPACSPILRKRSRSPTPQNQDGDTMVEKGSDHSSDKSPSTPEQGVQRSCSSQSGRSGG
                     KNSKKSQSWYNVLSPTYKQRNEDFRKLFKQLPDTERLIVDYSCALQRDILLQGRLYLS
                     ENWICFYSNIFRWETLLTVRLKDICSMTKEKTARLIPNAIQVCTDSEKHFFTSFGARD
                     RTYMMMFRLWQNALLEKPLCPKELWHFVHQCYGNELGLTSDDEDYVPPDDDFNTMGYC
                     EEIPIEENEVNDSSSKSSIETKPDASPQLPKKSITNSTLTSTGSSEAPVSFDGLPLEE
                     EVMEGDGSLEKELAIDNIIGEKIEIMAPVTSPSLDFNDNEDIPTELSDSSDTHDEGEV
                     QAFYEDLSGRQYVNEVFNFSVDKLYDLLFTNSPFLRDFMEQRRFSDIIFHPWKKEENG
                     NQSRVILYTITLTNPLAPKTATVRETQTMYKASQESECYVIDAEVLTHDVPYHDYFYT
                     INRYTLTRVARNKSRLRVSTELRYRKQPWGFVKTFIEKNFWSGLEDYFRHLETELTKT
                     ESTYLAEIHRQSPKEKASKSSAVRRRKRPHAHLRVPHLEEVMSPVTTPTDEDVGHRIK
                     HVAGSTQTRHIPEDTPDGFHLQSVSKLLLVISCVLVLLVVLNMMLFYKLWMLEYTTQT
                     LTAWQGLRLQERLPQSQTEWAQLLESQQKYHDTELQKWREIIKSSVLLLDQMKDSLIN
                     LQNGIRSRDYTAESDEKRNRYH"
     exon            472..549
                     /gene="Gramd1b"
                     /gene_synonym="3222402H23; A930008A22Rik; mKIAA1201"
                     /inference="alignment:Splign:2.1.0"
     exon            550..760
                     /gene="Gramd1b"
                     /gene_synonym="3222402H23; A930008A22Rik; mKIAA1201"
                     /inference="alignment:Splign:2.1.0"
     exon            761..781
                     /gene="Gramd1b"
                     /gene_synonym="3222402H23; A930008A22Rik; mKIAA1201"
                     /inference="alignment:Splign:2.1.0"
     exon            782..866
                     /gene="Gramd1b"
                     /gene_synonym="3222402H23; A930008A22Rik; mKIAA1201"
                     /inference="alignment:Splign:2.1.0"
     exon            867..970
                     /gene="Gramd1b"
                     /gene_synonym="3222402H23; A930008A22Rik; mKIAA1201"
                     /inference="alignment:Splign:2.1.0"
     exon            971..1066
                     /gene="Gramd1b"
                     /gene_synonym="3222402H23; A930008A22Rik; mKIAA1201"
                     /inference="alignment:Splign:2.1.0"
     exon            1067..1147
                     /gene="Gramd1b"
                     /gene_synonym="3222402H23; A930008A22Rik; mKIAA1201"
                     /inference="alignment:Splign:2.1.0"
     exon            1148..1263
                     /gene="Gramd1b"
                     /gene_synonym="3222402H23; A930008A22Rik; mKIAA1201"
                     /inference="alignment:Splign:2.1.0"
     exon            1264..1420
                     /gene="Gramd1b"
                     /gene_synonym="3222402H23; A930008A22Rik; mKIAA1201"
                     /inference="alignment:Splign:2.1.0"
     exon            1421..1610
                     /gene="Gramd1b"
                     /gene_synonym="3222402H23; A930008A22Rik; mKIAA1201"
                     /inference="alignment:Splign:2.1.0"
     exon            1611..1754
                     /gene="Gramd1b"
                     /gene_synonym="3222402H23; A930008A22Rik; mKIAA1201"
                     /inference="alignment:Splign:2.1.0"
     exon            1755..1873
                     /gene="Gramd1b"
                     /gene_synonym="3222402H23; A930008A22Rik; mKIAA1201"
                     /inference="alignment:Splign:2.1.0"
     exon            1874..2016
                     /gene="Gramd1b"
                     /gene_synonym="3222402H23; A930008A22Rik; mKIAA1201"
                     /inference="alignment:Splign:2.1.0"
     exon            2017..2120
                     /gene="Gramd1b"
                     /gene_synonym="3222402H23; A930008A22Rik; mKIAA1201"
                     /inference="alignment:Splign:2.1.0"
     exon            2121..2324
                     /gene="Gramd1b"
                     /gene_synonym="3222402H23; A930008A22Rik; mKIAA1201"
                     /inference="alignment:Splign:2.1.0"
     exon            2325..2415
                     /gene="Gramd1b"
                     /gene_synonym="3222402H23; A930008A22Rik; mKIAA1201"
                     /inference="alignment:Splign:2.1.0"
     exon            2416..2523
                     /gene="Gramd1b"
                     /gene_synonym="3222402H23; A930008A22Rik; mKIAA1201"
                     /inference="alignment:Splign:2.1.0"
     exon            2524..2641
                     /gene="Gramd1b"
                     /gene_synonym="3222402H23; A930008A22Rik; mKIAA1201"
                     /inference="alignment:Splign:2.1.0"
     exon            2642..7488
                     /gene="Gramd1b"
                     /gene_synonym="3222402H23; A930008A22Rik; mKIAA1201"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5946..5951
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gramd1b"
                     /gene_synonym="3222402H23; A930008A22Rik; mKIAA1201"
                     /note="hexamer: AATAAA"
     polyA_site      5971
                     /gene="Gramd1b"
                     /gene_synonym="3222402H23; A930008A22Rik; mKIAA1201"
                     /note="major polyA site"
     regulatory      7452..7457
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gramd1b"
                     /gene_synonym="3222402H23; A930008A22Rik; mKIAA1201"
                     /note="hexamer: ATTAAA"
     polyA_site      7484
                     /gene="Gramd1b"
                     /gene_synonym="3222402H23; A930008A22Rik; mKIAA1201"
                     /note="major polyA site"
ORIGIN      
        1 ggatagtgcc acgggcccca gggtagggag ccgagagagg aagcctcgag ccaggctgca
       61 ggcggagggc acggagcagc ggccagggac cccgatgccg gcggccaaca tgatggagaa
      121 cctgcagctg cccgccctgc aggtgccaga acctcagggc gcacccgagg gcagcgcggt
      181 gtggtccagc tcgtccaccc ccacgcttcg ccgccggcgc tttaagatgc gccggatgaa
      241 gaacgtgcag gagcagagcc tggaggcggg gttggtagcc ccggacctac ccggcgtcct
      301 ggcccccggc aaggagttcc tgcaactgcc gtccattgag attacgccct ccagcgacga
      361 ggacaccccg tggtccaact gctccacacc cagtgcgtcc ccgcgccgaa aacgcttcct
      421 gctccgcaag tggctgaggg tgagggagcg gaaagaatgc agtgaaagca gcagccagca
      481 aagcagccaa cagagcagcc acgacgatga ttcgagcagg ttcctgagtc ctcgagtgcg
      541 cgacgaaagc actgccagta actccaaccg cagcacgcca gcctgctctc ccatcctccg
      601 gaagcggtcc cgctcaccaa caccacagaa ccaggacgga gacaccatgg tggagaaggg
      661 ctcagatcac tcctcggaca agtccccgtc caccccggag cagggtgtgc aacgcagttg
      721 ctcctcacag tctggtcgga gcggtggtaa aaattccaag aaaagccaga gttggtacaa
      781 tgtgctaagc cccacttaca agcagagaaa tgaagacttc agaaagctct ttaagcaact
      841 tccagacacg gagcgcctca ttgttgatta ctcttgtgca ctccaaagag acattcttct
      901 tcagggccga ctctacctct cagaaaattg gatctgcttc tacagcaaca tcttccgctg
      961 ggaaaccctg ctgacagtcc gtttgaaaga tatctgctcc atgactaaag agaaaacagc
     1021 tcgcctcatt cccaatgcca tccaagtctg cactgattca gaaaagcact tttttacttc
     1081 ctttggagcc cgggacagga cgtacatgat gatgttccgg ctctggcaga atgctctcct
     1141 tgaaaagccc ctatgtccca aggagctctg gcactttgtc caccagtgct acgggaacga
     1201 gctgggccta accagtgatg atgaggacta cgtgcctcca gatgatgact tcaacacaat
     1261 gggctactgt gaggagatcc ccatagaaga gaatgaagtg aatgacagct catccaaaag
     1321 tagcatcgag accaagccgg atgccagccc acagctgccc aagaagtcca ttaccaacag
     1381 cacactgacg tctacgggaa gcagtgaagc ccctgtttcg tttgatggct tgccattgga
     1441 ggaggaggtg atggaggggg atggttccct agagaaggag cttgccattg acaacatcat
     1501 aggggagaag atcgagatca tggcgcctgt gacctcccct tcgctggact tcaatgacaa
     1561 tgaggatatc cccaccgagc tcagtgattc ttcagatacc cacgatgaag gagaggtcca
     1621 ggccttctat gaggacctga gtggaagaca atatgtgaat gaggtcttca acttcagcgt
     1681 ggacaaactc tatgacctgc tgttcaccaa ctcacccttc ctgcgggatt tcatggagca
     1741 gcggcgtttc tctgatatca tcttccatcc atggaaaaag gaggagaatg gaaaccagag
     1801 tcgagtgatt ctctacacta tcaccctcac taatcctctg gctcccaaaa cagccactgt
     1861 cagggagaca cagaccatgt acaaagcgag tcaggagagc gaatgctacg tgatagatgc
     1921 tgaagtcctc acccacgatg tgccgtacca tgactacttc tacaccatca atcgctacac
     1981 actcaccaga gtggcccgga acaagagcag actcagggtc tccacagagc tccgctatcg
     2041 aaaacagccc tgggggtttg tgaaaacgtt catcgagaag aacttctgga gtggactgga
     2101 ggactacttc cgtcatttag agactgaact aaccaaaaca gagagtacct acttggctga
     2161 gatacacagg cagtcaccca aggagaaggc tagcaagtct tcagcagtcc ggaggaggaa
     2221 gcgtccccat gcccacctgc gggtgcctca cctggaagaa gtgatgagtc ctgtcaccac
     2281 acccactgat gaagatgtgg gccacaggat caagcacgtg gcaggttcca cgcagacacg
     2341 gcacatcccg gaggacactc ctgatggttt tcacctacaa agtgtgtcca agctgctgct
     2401 ggttatcagc tgtgttctgg tgctgctggt tgtccttaac atgatgctct tctacaagct
     2461 gtggatgctg gaatacacca cccagaccct cactgcctgg cagggtctca ggctccagga
     2521 aaggttaccc cagtctcaga cagaatgggc ccagctatta gaatcccaac agaagtacca
     2581 cgacaccgag ctccagaagt ggagggaaat catcaaatcc tcagtgttgc tcctggacca
     2641 gatgaaggac tcgcttatca atcttcagaa tggtatcagg tcccgagact acacagctga
     2701 gagcgacgag aagaggaacc gctatcattg acaaggcagg accaggggtg gctacaagag
     2761 gcctgtgcaa tacatgtaca tagaccctat aaatatatat aaatatatat atacagaata
     2821 taaatatata ttatatacag attttaaaaa aagagataat gcctatgtac cagggagaag
     2881 gagcgggaac tcccgccccc tgtgccggcc agagcagcgt tttccctcca cggtggaggg
     2941 accgaggagg gcagggacca cctctcagca ccaacctccc ctgatcctcc tcccattttt
     3001 ctgttcctca tcccttccct tgccggccat tcttggccct tagaagggga atgtggctga
     3061 gccaaagttt atgcctgtga agaccttggt cgtcttcaat gtcattgttt caagagggca
     3121 ttgcttaagg tgcttcattt cctaaccccc ttttaatttg tctctagaat aaaagagaac
     3181 ctgttttcct cccaccccac ccacccccac ccagtgctac cccaggcctt cccttgggaa
     3241 cagaaagaat ggagcaggca ggagccccat tcaaagtccc tcaggaggcc gtcagttagg
     3301 accacactga aatccaggtg gtgaggactg tgacagaggc tgcgtttgtc ggcctgggct
     3361 gcggggctgc aggctcctga gctctggcat cctaagcgag ttcttcctca gccacgctcc
     3421 ccacccccac acaccttctt ctctcctgag taggttgtgg acccaacaag ggctgggaat
     3481 cccttagtcg cccactccct ttctctctgg tcttctccca ggctggatct gggggaaggg
     3541 tcacttttta gtgcctaaaa tcctgttgtt tctgtgtgcc ctaagagcac attgtttctt
     3601 agccagggtg gagccttttt gaccttgttt caaaaacaaa acaacaacct ctcttagtgg
     3661 aagcaagtca ggtctgtggc tctaattctt tctctttgat ctgtgagttt gatgtccagg
     3721 ataagtcagg gtatcctagt ccctcagggc tttgggagac agagaacgat ctagaaacat
     3781 ggattgcagg gcttgcccag aatcctgtgt gaggagtgag catagtcgcc aagccactta
     3841 gagggctaac agcatcatta actcttggta aggaaccagc attagcaata gaggcagctc
     3901 tgtgccactg tgtgtcacta aagggaggat ttggcacaga tgcatttgtt tggtcaggag
     3961 aagaccaact agaacctggc cacctcagtt ctaagtttct caggtttagt agtgggtttc
     4021 tgaaggtatg tgtacaaatc gctttatcgt ctttggccct agtgagatag aaaaccacca
     4081 agaaattaaa agcagatgct acgttgggat cttgaaccat ccagggcctt cttaatgtta
     4141 gcccgtcagg actcgggttt tatctgatct caagaggtcc ttctgggcag atccatcacc
     4201 ctcccttaca agtgtctact gcttttcctt ccatctgatg gttcaaggaa tcctgccagc
     4261 ccctggcaga gttcttagag atccatggta gtaaagattg ctgccaggtt ggcatgaaag
     4321 ctgctttaag cttgctgctt ttccagggct tctgaagaag gaaacctgga tttcctagag
     4381 cattagtaca gaggaagcaa gatggcgctg attagctaca ccagagaaga agttatgctc
     4441 tcctcttaga attgtccgaa cattccattt tgggcagtga aagaaaggca tccatgttgc
     4501 attgccctga agaaacaggt gttggtattt cttgaatatt tccagatcat cttctgatgg
     4561 agggaggaga aggctcctac ggttagtgag cattgctagc actcttctgg gaaagcaggg
     4621 tgaggaatgg attcatgtgt tcctctggag tagacaaggc acaaagacca cttgattgtc
     4681 attgggttgt tttgagagtt gctggtgaca gtcaagtccc aagtcaaaga agggaggatg
     4741 gtccagggag ctaggcagct tcttcttgga atagccagac gccagaagca ttcccagaaa
     4801 gcttttgaaa gcaaaattgg aaattctcag atttattaca tatgtagttc tttactaggt
     4861 ttaattgtta aggtaaccgt gatcttttaa aacaatttca gaagtattca ttggggtggg
     4921 atgggagttg ggggacaaaa taaagtaaca gaagtggccc taaccaccaa gaactgctgt
     4981 tcgttgacct gcagtatcat ttagaggagg agagcaccta atttgtcaga gaaagcctcc
     5041 tgtcatctag tgaacccaga tgatatgtgt acatgaagaa tagcccccaa gaatgatggc
     5101 tttctcgtga gttccttctg tcttagcatt agcttgggtt tttacacctg gaagaaatca
     5161 aaatatcagt ttattctcag aaaaaaaatc tttcttcccc ttcgtccata ctttgtgaaa
     5221 ggattgggaa ttcaccccct gcagccaaag taccctggac aatagcctgg caagcagctc
     5281 attgtccaca ggagggcatg gaacctagct ggcttttggt tacttcatcc agctggcaag
     5341 ttttgttcac ttattgtaga tgtaagtata gtttgatctt ctgtgaggat ttgtgtagca
     5401 aggtatttga atgcttttta ctggactatg agagatctgg gcttgagttc ctggccatgt
     5461 tagtgcaaaa gtcatgtagc tttagataag tccctgacac caagcttcag gatccaagtg
     5521 ttaacaggaa agagctgaaa taaatgacct ttaatgtggt atctaggttt gaccttgatt
     5581 tggagggtag gccagagatg agagagatgg ggagtttcca gtcttggaag atgtcctgcc
     5641 agggcagata aactttgttc ttggctagaa ggtcttgggg cttccagtgg cagggacagt
     5701 cttgctcagc atgagcacga gaacacttcc ttctttcctt tggcatagtt ttacatggaa
     5761 ttggtttatg cttagagggt aacagcaaga agagcatcct tttggcccta gcccatcttc
     5821 catctccagg cactgtgaat cctttctact atccatactc ctcactgatg gaggagacta
     5881 tctgaagaag ccattcccag ttctagaact tctgtttttc tcagccaaac ccctgtcgca
     5941 atttgaataa attatgaaac cgttgctaaa atccttggct tgtgttaggg cacgggtatc
     6001 aggagtgagg agcaccaggg acccgcaaga ggaatttgcc acaagtggat tctctacttg
     6061 tccatagctc ctcccctatg ctggcactgg tttactcttc tcatagactg catctgttag
     6121 gatgaggtgt tggggaaacg actggcaaag ggaagactct tttggactat ttgtgctccc
     6181 agaagggtcc tttctgtgcc ataccatccc acttccttag ctctgcaggg cagccaaagc
     6241 cagccctggt cgttagggcc aaggagaaat agcaatcttc tctcttcccc caggtggcag
     6301 ggctgtgatg gcccttccta cacacctgga ctctgcctac ccactccagg actctctccc
     6361 tccccccaac cccatcccca tctctgagct atggggcaat cactcccatt ttacctttgc
     6421 catccttgac cttcgttcac cccgctccca cgcccccccc cccatcctcc agcaggctgg
     6481 ccccactccc ttccatctcc aagtcttctt ccagaggatg catttggatc ccagaggagt
     6541 gttttctgga agacaatctt tcaacatccc tacattcctg atatgaagca ggaatttgca
     6601 catggtgtag agagctccct ctcctgcctc tctgcccagc cttgttacct cactcctgct
     6661 ccagccattg tgatgggctc agccagctcc ctgttctgat gtgccctgca acaacagctc
     6721 aggggtcttg tgacttggag aggtcctcag caggcctggg agcccggatt ggagccttgg
     6781 ctgccgttga gaagcactta cctgccaaga tttgctgatg ccagacgatc taccccagca
     6841 tgtgaatgca taatggacat tgccatctct gccctttggt cctccttgct tctctccata
     6901 caataagaca cctccgaagc aaaatggcgg cccttgctcc aggcaggaca tcagactgtc
     6961 tggggagttg gccctgggct tctgtgttgt gtgcagagac tgcacagtaa aacagtcact
     7021 tttgccaaca agaatgtgtg gcgccccaca tctccctacc ttgcactcta gggccagacc
     7081 actctctgta tggaccagac catcttccca aacccatggt gctttccccc cgaccccact
     7141 caacctacat tctgaggagg ggagggatgg atcagaggcc atagtggccc cctggataat
     7201 cctgacatgg ggtagagtcg ggtgaggcag agggagcagc acccaacacc tgcactgggc
     7261 cacaagcggg aaagaacacg ggttggttgc agttgagttg ttgtctggcc gtctgtattt
     7321 ggatctttaa ctgtactttg cctggcgctg tgcgcaaggt ctgaaacctt attgctagta
     7381 cctagaaaca cacaaggcta tccagccaaa tcttaatgta aagtagctag agccatggaa
     7441 gtccagtatg aattaaagga aaaaaagtat tgaattacaa ataataaa
//
