LOCUS       NM_027898               2802 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus GRAM domain containing 1A (Gramd1a), transcript
            variant 2, mRNA.
ACCESSION   NM_027898
VERSION     NM_027898.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2802)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2802)
  AUTHORS   Ferrari,A., He,C., Kennelly,J.P., Sandhu,J., Xiao,X., Chi,X.,
            Jiang,H., Young,S.G. and Tontonoz,P.
  TITLE     Aster Proteins Regulate the Accessible Cholesterol Pool in the
            Plasma Membrane
  JOURNAL   Mol Cell Biol 40 (19), e00255-20 (2020)
   PUBMED   32719109
  REMARK    GeneRIF: Aster Proteins Regulate the Accessible Cholesterol Pool in
            the Plasma Membrane.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2802)
  AUTHORS   Nakano,Y., Wiechert,S. and Banfi,B.
  TITLE     Overlapping Activities of Two Neuronal Splicing Factors Switch the
            GABA Effect from Excitatory to Inhibitory by Regulating REST
  JOURNAL   Cell Rep 27 (3), 860-871 (2019)
   PUBMED   30995482
REFERENCE   4  (bases 1 to 2802)
  AUTHORS   Sandhu,J., Li,S., Fairall,L., Pfisterer,S.G., Gurnett,J.E.,
            Xiao,X., Weston,T.A., Vashi,D., Ferrari,A., Orozco,J.L.,
            Hartman,C.L., Strugatsky,D., Lee,S.D., He,C., Hong,C., Jiang,H.,
            Bentolila,L.A., Gatta,A.T., Levine,T.P., Ferng,A., Lee,R.,
            Ford,D.A., Young,S.G., Ikonen,E., Schwabe,J.W.R. and Tontonoz,P.
  TITLE     Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER
            Cholesterol Transport in Mammalian Cells
  JOURNAL   Cell 175 (2), 514-529 (2018)
   PUBMED   30220461
REFERENCE   5  (bases 1 to 2802)
  AUTHORS   Pan,J., Mor,G., Ju,W., Zhong,J., Luo,X., Aldo,P.B., Zhong,M.,
            Yu,Y., Jenkins,E.C., Brown,W.T. and Zhong,N.
  TITLE     Viral Infection-Induced Differential Expression of LncRNAs
            Associated with Collagen in Mouse Placentas and Amniotic Sacs
  JOURNAL   Am J Reprod Immunol 74 (3), 237-257 (2015)
   PUBMED   26073538
REFERENCE   6  (bases 1 to 2802)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
REFERENCE   7  (bases 1 to 2802)
  AUTHORS   Brady,K.P., Rowe,L.B., Her,H., Stevens,T.J., Eppig,J.,
            Sussman,D.J., Sikela,J. and Beier,D.R.
  TITLE     Genetic mapping of 262 loci derived from expressed sequences in a
            murine interspecific cross using single-strand conformational
            polymorphism analysis
  JOURNAL   Genome Res 7 (11), 1085-1093 (1997)
   PUBMED   9371744
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC158993.2.
            
            On Feb 1, 2018 this sequence version replaced NM_027898.3.
            
            Transcript Variant: This variant (2) lacks an alternate in-frame
            exon compared to variant 1. The resulting isoform (2) has the same
            N- and C-termini but is shorter compared to isoform 1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK154821.1, AK150032.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-276               AC158993.2         113050-113325       c
            277-493             AC158993.2         105811-106027       c
            494-514             AC158993.2         105701-105721       c
            515-599             AC158993.2         104958-105042       c
            600-703             AC158993.2         104705-104808       c
            704-799             AC158993.2         104522-104617       c
            800-880             AC158993.2         103284-103364       c
            881-993             AC158993.2         101911-102023       c
            994-1144            AC158993.2         101551-101701       c
            1145-1343           AC158993.2         100906-101104       c
            1344-1487           AC158993.2         100268-100411       c
            1488-1606           AC158993.2         97977-98095         c
            1607-1749           AC158993.2         97751-97893         c
            1750-1853           AC158993.2         96568-96671         c
            1854-2027           AC158993.2         96312-96485         c
            2028-2115           AC158993.2         96145-96232         c
            2116-2223           AC158993.2         94912-95019         c
            2224-2344           AC158993.2         94695-94815         c
            2345-2802           AC158993.2         92281-92738         c
FEATURES             Location/Qualifiers
     source          1..2802
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 19.3 cM"
     gene            1..2802
                     /gene="Gramd1a"
                     /gene_synonym="1300003M23Rik; D7Bwg0611e"
                     /note="GRAM domain containing 1A"
                     /db_xref="GeneID:52857"
                     /db_xref="MGI:MGI:105490"
     exon            1..276
                     /gene="Gramd1a"
                     /gene_synonym="1300003M23Rik; D7Bwg0611e"
                     /inference="alignment:Splign:2.1.0"
     exon            277..493
                     /gene="Gramd1a"
                     /gene_synonym="1300003M23Rik; D7Bwg0611e"
                     /inference="alignment:Splign:2.1.0"
     exon            494..514
                     /gene="Gramd1a"
                     /gene_synonym="1300003M23Rik; D7Bwg0611e"
                     /inference="alignment:Splign:2.1.0"
     exon            515..599
                     /gene="Gramd1a"
                     /gene_synonym="1300003M23Rik; D7Bwg0611e"
                     /inference="alignment:Splign:2.1.0"
     exon            600..703
                     /gene="Gramd1a"
                     /gene_synonym="1300003M23Rik; D7Bwg0611e"
                     /inference="alignment:Splign:2.1.0"
     exon            704..799
                     /gene="Gramd1a"
                     /gene_synonym="1300003M23Rik; D7Bwg0611e"
                     /inference="alignment:Splign:2.1.0"
     exon            800..880
                     /gene="Gramd1a"
                     /gene_synonym="1300003M23Rik; D7Bwg0611e"
                     /inference="alignment:Splign:2.1.0"
     exon            881..993
                     /gene="Gramd1a"
                     /gene_synonym="1300003M23Rik; D7Bwg0611e"
                     /inference="alignment:Splign:2.1.0"
     exon            994..1144
                     /gene="Gramd1a"
                     /gene_synonym="1300003M23Rik; D7Bwg0611e"
                     /inference="alignment:Splign:2.1.0"
     exon            1145..1343
                     /gene="Gramd1a"
                     /gene_synonym="1300003M23Rik; D7Bwg0611e"
                     /inference="alignment:Splign:2.1.0"
     exon            1344..1487
                     /gene="Gramd1a"
                     /gene_synonym="1300003M23Rik; D7Bwg0611e"
                     /inference="alignment:Splign:2.1.0"
     exon            1488..1606
                     /gene="Gramd1a"
                     /gene_synonym="1300003M23Rik; D7Bwg0611e"
                     /inference="alignment:Splign:2.1.0"
     exon            1607..1749
                     /gene="Gramd1a"
                     /gene_synonym="1300003M23Rik; D7Bwg0611e"
                     /inference="alignment:Splign:2.1.0"
     exon            1750..1853
                     /gene="Gramd1a"
                     /gene_synonym="1300003M23Rik; D7Bwg0611e"
                     /inference="alignment:Splign:2.1.0"
     exon            1854..2027
                     /gene="Gramd1a"
                     /gene_synonym="1300003M23Rik; D7Bwg0611e"
                     /inference="alignment:Splign:2.1.0"
     exon            2028..2115
                     /gene="Gramd1a"
                     /gene_synonym="1300003M23Rik; D7Bwg0611e"
                     /inference="alignment:Splign:2.1.0"
     exon            2116..2223
                     /gene="Gramd1a"
                     /gene_synonym="1300003M23Rik; D7Bwg0611e"
                     /inference="alignment:Splign:2.1.0"
     exon            2224..2344
                     /gene="Gramd1a"
                     /gene_synonym="1300003M23Rik; D7Bwg0611e"
                     /inference="alignment:Splign:2.1.0"
     exon            2345..2802
                     /gene="Gramd1a"
                     /gene_synonym="1300003M23Rik; D7Bwg0611e"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2783..2788
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gramd1a"
                     /gene_synonym="1300003M23Rik; D7Bwg0611e"
                     /note="hexamer: AATAAA"
     polyA_site      2802
                     /gene="Gramd1a"
                     /gene_synonym="1300003M23Rik; D7Bwg0611e"
                     /note="major polyA site"
ORIGIN      
        1 ctgtctccca gccggactct ttccccagcc atcctaggcc taggcccgcg ctcgcgtcca
       61 tgtccccctc ccggcggggg cggcgccgtg acgcgcgggg cgggagcagg aagggggtgt
      121 cgctgacgcc gaggcggcct ccggcggctc cggccttttg tgcgggtggc agggtccggt
      181 ggaggcggcg gccgaggcag gcgaggcccg ggaggcccat ctcagagcag ccggccgggt
      241 cctgccctgc agccggggcg ccgcatccat gttcgacacc acgccccact ctggccggag
      301 ctcccccagc agctccccgt ctcttcgtaa gcggcttcag ctcttgcccc caatccggcc
      361 ccctccggct tctgagccag aaccaggcac catggtggag aaggggtctg acagctcctc
      421 tgagaaaagt ggcgtgtcgg ggacactcag cacccagagc ctgggcagcc ggaacttcat
      481 ccgcaacagt aagaagatgc agagctggta cagtatgctg tgtcccacat acaaacaacg
      541 caacgaggac ttccggaaac tgttcagcaa acttcctgaa gcagagcgcc tcatcgtgga
      601 ttactcctgc gccctgcaga gggagatcct cctccagggc cgcctctacc tctctgagaa
      661 ctggatctgt ttctacagca acatcttccg ctgggagacc acaatttcca tccagttgaa
      721 ggaagtgacc tgtctgaaga aggagaagac ggctaagctc atccccaatg ccattcagat
      781 ctgtactgag agtgagaagc atttcttcac ttccttcggg gcccgagacc gctgcttcct
      841 cctcatcttc cgtctctggc agaacgcgct gcttgaaaag acactgagtc ctcgagagct
      901 ttggcacctg gtccatcagt gctatggctc ggagctgggc ctcaccagtg aagacgaaga
      961 ctatgtctgc cccttgcaac tgaatggtct tgggagtccc aaagaggtgg gagacgtgat
     1021 cgcactcagc gacatcagtc cctcgggggc ggctgaccac agccaggagc caagccctgt
     1081 gggttcaaga cgtggccggg tcaccccaaa cctctctcga gccagcagtg atgcagacca
     1141 tggggccgag gaggacaagg aagaacagac ggacggtctg gatgcctcct ccagccagac
     1201 agtgacccca gtagcagaac cgctgagttc tgagccgaca ccaccagatg ggcccacttc
     1261 ctccttgggt cccttggatc tgctgtctag agaggaacta ttgacagaca cgagtaactc
     1321 gtcctcatcc actggggagg aaggtgacct ggctgcactg ctgcctgacc tctccggccg
     1381 gctcctcatc aattctgtct tccacatggg tgctgagcgt ctgcagcaga tgctcttctc
     1441 ggactctccg ttcctgcaag gcttcctgca gcagcgcaag ttcacagatg tgaccttgag
     1501 cccttggagc agtgacagca agtgccacca gcgcagagtc ctgacctaca ccatccccat
     1561 tagcaaccag ctaggcccca agagcgcctc tgtggtggag acacagacgc tgttccggcg
     1621 cggcccacag gcgggcgggt gcgtggtgga ctctgaggtg ctcacccagg gcatcccgta
     1681 ccaggactac ttctacactg cccaccgata ctgtatcctg ggtctggccc ggaacaaggc
     1741 ccggcttcgt gtatcctcag agatccgcta ccgaaagcaa ccgtggagcc tcgtaaagtc
     1801 gctcattgag aagaactcgt ggagcggcat cgaagattat ttccaccacc tggatcgaga
     1861 actcgccaag gcagaaaagc tgtccctgga ggaaggaggg aaagatacac gtggactact
     1921 gtcaggcctg cggaggagga agcggcccct gagctggagg gggcacagag atgggcctca
     1981 gcacccagac ccagacccct gcacccagac cagcatgcac acctcaggtt ccctcagctc
     2041 tcgcttctcg gaaccatctg tggatcaggg ccccggggca ggcatcccca gcgccctggt
     2101 tctcatcagc attgtcctca tcgttctcat cgccctcaat gccctcctct tctaccgtct
     2161 ctggtctctg gagagaacag cccatacctt tgagtcctgg cacagcctgg cactggccaa
     2221 gggcaagttc ccccagacag ccacggagtg ggcggagatc ttggctctgc agaagcactt
     2281 ccacagcgtt gaggtgcaca agtggaggca gatccttcga gcatccgtgg agctcctgga
     2341 tgagatgaag ttctccttgg agaagctaca tcaaggaatt actgtcccgg atcctcccct
     2401 ggacactcag ccacagcctg atgacagttt tccctgagga ctcctgattg aaaagccaca
     2461 cccctaaacg gacagaagga cacatggaac cctggcagtc actgctggca cagtgcgaat
     2521 gccgccggga ggttcctgcc tgcccctcac tgtggccctg ccaagagcca cacagacctg
     2581 gggaccatag aaccaagatg cactttagat ctgtgtgagc gattccagct gccactgcct
     2641 gctcagccag ggagctggcc tggtctttgg cagactcccc ctccaactaa cttattttgc
     2701 ccagctgggg ttgtgggggg caccttttgg ggtgcacaag aaccctctgg gtttaatgta
     2761 tttatttggg aataatgacc ccaataaagg gttggaaatg gc
//
