LOCUS       NM_183183               3116 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus GPRIN family member 3 (Gprin3), mRNA.
ACCESSION   NM_183183
VERSION     NM_183183.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3116)
  AUTHORS   Karadurmus,D., Rial,D., De Backer,J.F., Communi,D., de Kerchove
            d'Exaerde,A. and Schiffmann,S.N.
  TITLE     GPRIN3 Controls Neuronal Excitability, Morphology, and
            Striatal-Dependent Behaviors in the Indirect Pathway of the
            Striatum
  JOURNAL   J Neurosci 39 (38), 7513-7528 (2019)
   PUBMED   31363062
  REMARK    GeneRIF: we identified GPRIN3 as a putative selective controller of
            D2R function in the striatum playing a critical role in
            striatal-associated behaviors and cellular functions
REFERENCE   2  (bases 1 to 3116)
  AUTHORS   Jones,M.R., Dilai,S., Lingampally,A., Chao,C.M., Danopoulos,S.,
            Carraro,G., Mukhametshina,R., Wilhelm,J., Baumgart-Vogt,E., Al
            Alam,D., Chen,C., Minoo,P., Zhang,J.S. and Bellusci,S.
  TITLE     A Comprehensive Analysis of Fibroblast Growth Factor Receptor 2b
            Signaling on Epithelial Tip Progenitor Cells During Early Mouse
            Lung Branching Morphogenesis
  JOURNAL   Front Genet 9, 746 (2019)
   PUBMED   30728831
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3116)
  AUTHORS   Mototani,Y., Okamura,T., Goto,M., Shimizu,Y., Yanobu-Takanashi,R.,
            Ito,A., Kawamura,N., Yagisawa,Y., Umeki,D., Nariyama,M., Suita,K.,
            Ohnuki,Y., Shiozawa,K., Sahara,Y., Kozasa,T., Saeki,Y. and
            Okumura,S.
  TITLE     Role of G protein-regulated inducer of neurite outgrowth 3 (GRIN3)
            in beta-arrestin 2-Akt signaling and dopaminergic behaviors
  JOURNAL   Pflugers Arch 470 (6), 937-947 (2018)
   PUBMED   29500670
  REMARK    GeneRIF: GRIN3 is involved in regulation of dopamine-dependent
            behaviors and is essential for activation of the dopamine receptors
            (DAR)-beta-arrestin signaling cascade.
REFERENCE   4  (bases 1 to 3116)
  AUTHORS   Collins,M.O., Yu,L., Coba,M.P., Husi,H., Campuzano,I.,
            Blackstock,W.P., Choudhary,J.S. and Grant,S.G.
  TITLE     Proteomic analysis of in vivo phosphorylated synaptic proteins
  JOURNAL   J Biol Chem 280 (7), 5972-5982 (2005)
   PUBMED   15572359
REFERENCE   5  (bases 1 to 3116)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
REFERENCE   6  (bases 1 to 3116)
  AUTHORS   Iida,N. and Kozasa,T.
  TITLE     Identification and biochemical analysis of GRIN1 and GRIN2
  JOURNAL   Methods Enzymol 390, 475-483 (2004)
   PUBMED   15488195
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC131708.3.
            
            On Feb 8, 2019 this sequence version replaced NM_183183.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK050148.1, AK173336.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-147               AC131708.3         60360-60506
            148-3116            AC131708.3         131237-134205
FEATURES             Location/Qualifiers
     source          1..3116
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 28.48 cM"
     gene            1..3116
                     /gene="Gprin3"
                     /gene_synonym="C030038J10Rik; C730021L23"
                     /note="GPRIN family member 3"
                     /db_xref="GeneID:243385"
                     /db_xref="MGI:MGI:1924785"
     exon            1..147
                     /gene="Gprin3"
                     /gene_synonym="C030038J10Rik; C730021L23"
                     /inference="alignment:Splign:2.1.0"
     exon            148..3116
                     /gene="Gprin3"
                     /gene_synonym="C030038J10Rik; C730021L23"
                     /inference="alignment:Splign:2.1.0"
     CDS             257..2548
                     /gene="Gprin3"
                     /gene_synonym="C030038J10Rik; C730021L23"
                     /note="GRIN3"
                     /codon_start=1
                     /product="G protein-regulated inducer of neurite outgrowth
                     3"
                     /protein_id="NP_899006.1"
                     /db_xref="CCDS:CCDS20199.1"
                     /db_xref="GeneID:243385"
                     /db_xref="MGI:MGI:1924785"
                     /translation="MGTVPDPLRVTKASIVAASGKEESRGESQSVSPQPAQPDNNASG
                     IGNVPAELSLQLSAAAQALMQACVSESSQQDMASPGVFSEGEPVSPKQKTPDDFLLHG
                     SKESAAPGLNATAQKELISAPCLISVVQHTHHAIQRDAPNTSTCAVPEGSLVKSEANS
                     NGENPEKPGCPARVTCCSSKNQEGLCDFPSPENSQGILQTPDIASPSADRPEGEGQKV
                     INNITAVSSEPPVREGCSENKQPSATALNTTAERSENPPPSHLTSKGATCSSEARQAL
                     LPAQYPVSRFKEASTMTCQAESGAKEVSGRAWQDAEVQAVASVESRSVSTSPSILPAY
                     LKENPAPELENGQEQLRVICHGKGSGNHLLELSNSMVDSQESRQCPSIVPQVHIQAAT
                     ATPAAFKGGCKPANQPAEGLKSPLIHVTSSQNTETEEDLRLSASKEATSRQPEGTNPD
                     FQKANAIGQISLPAGSQAEINQGLWNSGPREPEIVVKTAKDHKAESSCKPSNSGGGAN
                     KDYPPESLDPTDKKGAKDKKPASPLIVKDHAPGATSTLDAKTLLLNPKSQVKEGEGPE
                     VSPAPSPGRKSQQNTLEELRQPKTVMSLSLPSDGTGDSSPGSGKRTPSLSVKASPRRG
                     SRVSEFLKELSVTAAAAQVGLTPGEKKKQLGADSKLHLKQSKRVRDVVWDDQGMTWEV
                     YGASLDPESLGVAIQNHLQRQIREHEKIVKTQSGQTRRSISSDSSSSKKLKGRQHGVL
                     QSMLQNFRRPNCCVRPAPSSVLD"
     regulatory      2727..2732
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gprin3"
                     /gene_synonym="C030038J10Rik; C730021L23"
                     /note="hexamer: AATAAA"
     polyA_site      2754
                     /gene="Gprin3"
                     /gene_synonym="C030038J10Rik; C730021L23"
                     /note="major polyA site"
ORIGIN      
        1 agttcctgat cgcgcagagc tggctcctgg ctgcagggga ctgctcaagt cacccagcag
       61 cagtgtggca gagccagggc tgggaatcga ctagaagccc agcaccgcgc agacagcggc
      121 ccagcggggg acaccccacc ggagcaggcc agttcagcca aggactcatc cctatggctt
      181 ccctctgagt tccaactact tcccagtgga aaacatactt ggaatagaca ctggagcgat
      241 cttggaaaga ggtcccatgg ggactgtacc tgaccctctg agggtgacta aagcttcgat
      301 agtggcagct tctggaaagg aagagtctcg aggggagtcg cagagtgtct caccacaacc
      361 agctcagcca gataacaatg ctagtggcat tggcaatgtt cctgcagaac tcagcctcca
      421 gctcagtgca gctgctcaag ccctgatgca agcttgtgtg tctgagtcca gtcagcaaga
      481 catggcatct cctggtgtct tcagtgaggg agagccagtg tctcccaaac agaaaacacc
      541 tgatgacttc ctgcttcatg gaagcaagga gtccgcagct ccaggcctga acgctactgc
      601 acaaaaggaa cttatatctg cgccatgttt aatatctgta gtccagcaca ctcaccatgc
      661 catccaaagg gatgcaccaa atactagcac ctgtgcggta cctgaaggtt ccttggtgaa
      721 atccgaggca aactcaaacg gcgagaaccc tgaaaagcca ggttgtcctg ccagggtcac
      781 ctgttgcagc agcaaaaatc aagaagggct ctgtgatttt ccttctccag aaaacagcca
      841 aggaatttta cagactccag atatagcatc cccttctgca gacagacctg agggggaagg
      901 gcagaaagtc atcaataaca tcaccgcggt gtccagtgaa cctccagtaa gagaggggtg
      961 ctcggagaac aaacagccct ctgccactgc cttgaacacc acagctgaaa ggtcggaaaa
     1021 ccctccgccg tcccacctca ccagcaaagg ggccacatgt tcttcagaag caaggcaggc
     1081 actgctacca gcacagtatc ctgtgtcaag gtttaaagaa gccagtacaa tgacctgcca
     1141 agctgaaagt ggggctaagg aggtctctgg cagggcttgg caagatgctg aggtacaggc
     1201 agtggcaagt gtggagagca ggtctgtctc taccagcccc agtatcctcc ccgcatattt
     1261 aaaagaaaat cctgctcctg agctagagaa tgggcaggag caactgcgtg tcatttgcca
     1321 tggcaagggc agtgggaacc acttgttgga actctctaac agcatggtag actcccagga
     1381 gtcaaggcaa tgccccagca ttgtaccaca ggtgcatatc caagcagcca ctgccactcc
     1441 tgcggctttc aaagggggat gcaaaccagc gaaccaacca gctgaaggcc ttaaatcccc
     1501 actgatccat gtgacctcca gtcaaaacac ggaaacagag gaagacctgc ggttgtcagc
     1561 aagcaaagag gcaacctcta gacagcctga aggtactaat cctgacttcc agaaagctaa
     1621 cgccattggc cagatttccc tcccagcagg gagtcaagct gagataaatc aggggttgtg
     1681 gaactctgga cccagggaac ctgaaattgt agtgaaaact gcaaaagacc acaaagcaga
     1741 gtcaagctgc aaaccgtcca actccggtgg aggtgccaac aaagactacc ccccggagag
     1801 cttggacccc actgataaaa aaggtgcaaa ggacaagaag cctgcgtctc ctcttatcgt
     1861 gaaagaccat gcacctggag ccaccagcac tctagatgcc aaaaccctat tgctaaatcc
     1921 taaatctcag gtaaaggaag gtgagggacc agaggtcagt cctgcaccct ccccagggag
     1981 gaagagccaa cagaacacct tggaagaact caggcagccc aagacagtca tgagtctgag
     2041 cctgccatca gatggcacag gtgactcgag cccaggctca ggtaagagga ccccttctct
     2101 ctcagtcaag gccagcccgc gcaggggcag ccgggtcagc gagttcctga aggagctcag
     2161 tgtgacagca gctgctgctc aggtgggcct cacacctgga gagaagaaga aacagctggg
     2221 tgcagactcc aagctgcatc tgaaacagtc caagcgagtg agggatgtgg tgtgggatga
     2281 ccagggcatg acctgggagg tgtatggtgc ttccttggac ccagagtccc tgggagttgc
     2341 catccagaac catttacaaa gacaaattag ggaacatgag aagatagtta aaacacaaag
     2401 tggccagact cgaagatcaa tttcctcaga ttcttcttca agtaagaagc ttaaagggag
     2461 acaacatggt gttctgcagt ccatgctgca aaacttccgg cgccccaact gctgtgtccg
     2521 ccctgctccg tcctctgtgc tggactaaaa gggaactgca ctagtgtacg agctgtggta
     2581 ttccttgtgt ctatttgtgt caaagcttag acgtttggat ttctgttttg ttttaggttt
     2641 gttgtcgttg ttttctgaga gacctaggag taaacgcaac tattagattt aaaaattagc
     2701 tattaggaat tgttgggttt tccacaaata aaatgctgtt tcccactgat agaatacaag
     2761 agtgaagcaa agcttacagc ttgcacgagt tcagaagaaa tgatcgtcac tgtggttttt
     2821 aaggacatta tttatacaca gaagtcattc ggtattttca cctcagtcta tcacaggatg
     2881 gtatttccac taaaatagct gctttacact aaaactagca aaaacaacta ctaacaacac
     2941 tgtggtaatt tctggtatta ctgaggtaag aatgctagta ccacaaaatg ttgcaagtac
     3001 cacaagagga tgctagaacc acaaatgttt aagtagcttt taagaacctt aatgtgaaaa
     3061 cttgaaaaac aaatgtatgt tatcccaggg acaaataaga taaaatgaaa atattc
//
