LOCUS       NM_012014               4147 bp    mRNA    linear   ROD 15-NOV-2024
DEFINITION  Mus musculus G protein-regulated inducer of neurite outgrowth 1
            (Gprin1), transcript variant 1, mRNA.
ACCESSION   NM_012014 XM_484262
VERSION     NM_012014.5
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4147)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4147)
  AUTHORS   Pujol,C.N., Dupuy,V., Seveno,M., Runtz,L., Bockaert,J., Marin,P.
            and Chaumont-Dubel,S.
  TITLE     Dynamic interactions of the 5-HT6 receptor with protein partners
            control dendritic tree morphogenesis
  JOURNAL   Sci Signal 13 (618) (2020)
   PUBMED   32047117
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4147)
  AUTHORS   Kanellopoulos,A.H., Koenig,J., Huang,H., Pyrski,M., Millet,Q.,
            Lolignier,S., Morohashi,T., Gossage,S.J., Jay,M., Linley,J.E.,
            Baskozos,G., Kessler,B.M., Cox,J.J., Dolphin,A.C., Zufall,F.,
            Wood,J.N. and Zhao,J.
  TITLE     Mapping protein interactions of sodium channel NaV1.7 using
            epitope-tagged gene-targeted mice
  JOURNAL   EMBO J 37 (3), 427-445 (2018)
   PUBMED   29335280
REFERENCE   4  (bases 1 to 4147)
  AUTHORS   Trinidad,J.C., Specht,C.G., Thalhammer,A., Schoepfer,R. and
            Burlingame,A.L.
  TITLE     Comprehensive identification of phosphorylation sites in
            postsynaptic density preparations
  JOURNAL   Mol Cell Proteomics 5 (5), 914-922 (2006)
   PUBMED   16452087
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC162526.3.
            
            On Jan 26, 2022 this sequence version replaced NM_012014.4.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Both variants 1 and 2 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK138306.1, SRR7652917.638518.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849382, SAMN00849385
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-104               AC162526.3         172288-172391       c
            105-204             AC162526.3         164727-164826       c
            205-4147            AC162526.3         159389-163331       c
FEATURES             Location/Qualifiers
     source          1..4147
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 29.18 cM"
     gene            1..4147
                     /gene="Gprin1"
                     /gene_synonym="Z16"
                     /note="G protein-regulated inducer of neurite outgrowth 1"
                     /db_xref="GeneID:26913"
                     /db_xref="MGI:MGI:1349455"
     exon            1..104
                     /gene="Gprin1"
                     /gene_synonym="Z16"
                     /inference="alignment:Splign:2.1.0"
     exon            105..204
                     /gene="Gprin1"
                     /gene_synonym="Z16"
                     /inference="alignment:Splign:2.1.0"
     exon            205..4147
                     /gene="Gprin1"
                     /gene_synonym="Z16"
                     /inference="alignment:Splign:2.1.0"
     CDS             359..3157
                     /gene="Gprin1"
                     /gene_synonym="Z16"
                     /codon_start=1
                     /product="G protein-regulated inducer of neurite outgrowth
                     1"
                     /protein_id="NP_036144.2"
                     /db_xref="CCDS:CCDS26534.1"
                     /db_xref="GeneID:26913"
                     /db_xref="MGI:MGI:1349455"
                     /translation="MRDCCSSPKAIPAPPRHALDQSLGMDPRHTSSSGAAEGASCSER
                     PAGSLACPSPNCSPLPETPRAHGALTSDNSGTTLFGKPEPMSSAEATPTASEIRNPVF
                     SGKMDGNSLKQADSTSTRKEEAGSLRNEESMLKGKAEPMIYGKGEPGTVGRVDCTASG
                     AENSGSLGKVDMPCSSKVDIVSPGGDNAGSLRKVETISSGKMDPKTENVMHSRRERPG
                     STGEGDLVSLRENDMKPPDNTDSASTKKTDPEFSGKLTPGSSGKTELVSSVTVAPVTS
                     ENVNPVCSGGAGPAAVGNSETLSSVKKDPQLLGKKEAVSSGEGGSVSVRMAETVSARQ
                     PEGMFPAKTDSTSSNSTGPSGRADPVSLRNSELVSPVKPERLSSGQAERVSLVKTETL
                     SSGKEDPRSSRRVDHTTVTGNMQTSQKGNPESSGKTDLGSSSSGDTRSLGTWGSLSAA
                     KAEVTEGKGDPQPWKKASLPASEKTDPLASSKAGSASQGKAETVSPGEVDAMTLGKTV
                     PTSSGKTALVSPGKVDLMTSERAEGIPELQASEKGNPVNSTRVDTGATGSTEPKSGVK
                     VITQIPGATSPGKVETPSLQKEQPQLSEKTDPSRKVDPPTTVEPVSLGKADSASPSPR
                     KAESQTSAKTVPQAPDKATSSLRQSDGTPYSSAQPQRDTRSIGSLPEREPSASTSQKD
                     LAAAAAQKSPSAEAAAPPPGPRTRDNFTKAPSWDAGAPPPREDAGTQAGAQACVSVAV
                     SPMSPQDGAGGPAFSFQAAPRAPSPAPRPPSRRDAGLQVSLGAAETRSVATGPMTPQA
                     AAPPAVPPVFPEVRVRPGSVLAAALAPQEATEPVRDVSWDEKGMTWEVYGASMEVEVL
                     GMAIQKHLERQIEEHGRQGAPAPAPPPAVRAGPGRAGSVRTAPAEGAAKRPPGLFRAL
                     LQSVRRPRCCSRAGPTAE"
     regulatory      4129..4134
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gprin1"
                     /gene_synonym="Z16"
                     /note="hexamer: AATAAA"
     polyA_site      4147
                     /gene="Gprin1"
                     /gene_synonym="Z16"
                     /note="major polyA site"
ORIGIN      
        1 agccgaccag ggacggcgcg gagtcgggtc cgcccgccag cgcggccgag gagcaccggg
       61 gtggtctgcg cggcgcgagc cggagctacg aggagccggc gcgggatatc cgatacatgg
      121 catcaagggg gtcacaaccc acagactgaa cactgccgct ctagggattc tggcctgagc
      181 atgggtgaga gagtctggat gcaggaccag atagctgact tgagctcaaa caggacgatg
      241 agggtagagc gtcagttcta aagacccagc ctggctccac ctgcttcaga aggactccag
      301 ccccctaaga tccctctgct ccccacagga tgggagcctg ggcactggag gcccggtcat
      361 gagggactgc tgctcctctc caaaggccat ccctgcaccc ccaaggcacg ccctggacca
      421 gagtttaggc atggacccca gacacaccag ttccagtggg gctgcggaag gggcctcctg
      481 ttctgagagg cctgctggga gcttagcctg cccttctcct aactgcagcc ctctcccaga
      541 gacaccgagg gcacatggag ccttgacctc agacaactct ggaacgactt tgtttgggaa
      601 gccagagccc atgtcctcag cagaagccac tcccacagcc tcagagatca gaaatcctgt
      661 gttctcgggg aagatggatg gcaactccct gaagcaggca gactccactt ccacacgaaa
      721 ggaagaggct gggtccttga ggaatgaaga gtccatgttg aagggaaagg cagagcctat
      781 gatctatgga aagggggagc ctgggacggt aggaagagtg gactgcacag cttcaggggc
      841 ggagaattct gggtccttgg gaaaagtaga catgccatgt tccagcaaag tggatatagt
      901 gtccccagga ggagacaatg ctgggtcttt aagaaaggta gagactatat cctcaggcaa
      961 aatggatcca aaaacagaga atgtcatgca ttccagaaga gagcgccctg gatccacagg
     1021 agagggagat cttgtgtctt tgagggaaaa tgatatgaaa cccccggaca acacagattc
     1081 tgcctccaca aaaaagacag accctgagtt ctctggaaag ctaactccag gatcgtcagg
     1141 caagacagag cttgtatcct cagtaactgt ggctcctgtg acctctgaaa atgtgaatcc
     1201 tgtatgctcg gggggagcag gtcctgcagc tgtgggcaat tcagaaactt tgtcctcagt
     1261 caagaaggac cctcagttgc ttggaaagaa agaggctgtc tcctcaggag aaggtgggtc
     1321 tgtatcggtg agaatggcag aaacagtgtc tgccagacag ccagaaggta tgtttccagc
     1381 aaagacagat tctacatctt ccaacagtac aggaccttca ggcagagcgg accctgtttc
     1441 cttaagaaat tcagaacttg tgtccccagt gaaaccagaa cgcttgtcct ctgggcaggc
     1501 agaacgcgtg tccttggtaa aaacagaaac attatcctca ggaaaagaag atccaaggtc
     1561 ttctagaagg gtggatcaca cgactgtcac aggaaacatg caaacatctc aaaaggggaa
     1621 tcccgagtct tcaggaaaga cagacctcgg gtcttcgagt tcaggagata ccaggtctct
     1681 ggggacttgg gggtccctgt ctgctgcaaa agctgaggtg actgagggga aaggagaccc
     1741 acagccctgg aagaaggcaa gtctcccagc ctcagagaag accgatcccc tggcttcaag
     1801 caaggcaggc tctgcaagcc agggaaaggc agaaacggtt tcccctggag aagtggacgc
     1861 catgacttta ggaaaaacgg tcccaacgag ttcaggaaaa acagctttgg tatccccagg
     1921 gaaggtggat ctcatgacct cagaaagagc agaaggcatc ccagagctgc aggcttcaga
     1981 gaaagggaat cctgttaact ccacacgggt ggacaccggg gccacaggga gtactgagcc
     2041 caaatctggg gtcaaagtga taacccagat tccaggtgcc acatccccgg gaaaggtgga
     2101 aactccgtct ttgcaaaagg agcagccaca actgtctgag aagacagatc cctccagaaa
     2161 agtcgacccc cccacgactg tggagcctgt gtccctgggg aaggctgact ctgcatctcc
     2221 atctcctaga aaagcagagt ctcagacttc cgccaagact gtccctcagg ccccagataa
     2281 ggccacgtcc tctctcaggc aatcagatgg cacaccctac agctcagccc agccccagag
     2341 agataccagg agcatcggat ccctgccaga gcgggagccc tctgccagca ccagccagaa
     2401 agacctagcg gcagcggcgg ctcagaagag ccccagcgcg gaggctgcgg cgccccctcc
     2461 agggccacgg actcgcgaca acttcaccaa ggcgccgtcg tgggacgccg gagcgccacc
     2521 gccacgcgag gacgcgggca cccaggcagg cgcgcaggcc tgcgtctcgg tggcggtgag
     2581 ccccatgtct ccgcaggacg gcgcgggtgg cccggccttc agcttccagg cggcgccgcg
     2641 cgcgcccagc cccgcgccca ggccaccatc gcgccgggac gcgggcctgc aggtgtcgct
     2701 gggagccgcc gagacacgct cggtggccac ggggcccatg actccgcagg ccgcagcgcc
     2761 gcccgccgtg ccgcccgtct tccccgaggt gcgggtgcgg ccaggctcgg tgttggcggc
     2821 cgccttggcg ccccaggagg cgaccgagcc ggtgcgcgac gtgagctggg acgagaaggg
     2881 catgacgtgg gaagtgtacg gtgcttccat ggaggtggag gtgctgggca tggccatcca
     2941 gaagcatttg gagcgtcaga tcgaggagca cggccgccaa ggggcgccgg cgccggcgcc
     3001 gccgcccgcc gtccgcgcgg gcccaggccg tgcaggctct gtgcgcaccg caccggcgga
     3061 gggcgccgcc aagcgcccgc cgggcctctt ccgcgcgctg ctgcagagtg tgcgccggcc
     3121 gcggtgctgc tcgcgggcgg gccccactgc ggagtgatct gtccctgttt tgtaggcccg
     3181 ggtttccaac cttctcaggc tcccttctcg aggtctggcc cttgaaagct atgttccacc
     3241 cccaagtgcg tcatgcctcc gaggagtgag ccgccttcag gggcttcttt ccaggccctt
     3301 ccttcccaaa cactgacgga aaaccccata tccagtccct ttgtggccag gagcccacac
     3361 acccagccct gacaactcca ccctggttcc ctcacagact tttgctccac tcccgcggga
     3421 actacgggaa gagcacaggg acctgctccc accctttcac cctacagctg aggcaggctc
     3481 ctgagatggc cagactggtg gtttgaggct tccagtgggc caggtcccca aaacggggaa
     3541 agactgcatg cagatcttta agtgttcttt cacgtgtgcc aggattgatg taaggccacc
     3601 agaaaggcag actctgaata ggaggagtct agggggaggg gagggagtga gtctctgagc
     3661 agtgagggtc tccacatggt gctggccccg tggccagggc atctgttgca tgctgttggt
     3721 agtcctaccc catccctgtc tctccccacc tagcccagta ccctagtcct atttcctccc
     3781 catcccagtc actatgcaca gttcccatag aggccaaagg ctaggaatgc cctggggctc
     3841 aactgaggag agtcatggaa aggtcagagg gtcttagaca ggaccaaagg tcattgtaag
     3901 gctcccagaa ggtctcagga cgtcgaccac ctgggtgaca gctggtcttg ggtattggga
     3961 acaggatgga ggtcccattt gatatccacg gttgtcttta aagattcccc tcttatccct
     4021 ctccccgaca cgcacaatgc tgtgagcccc aagttccttg taaccactga gtgccctggt
     4081 ccctctagcc tccgtttttg gctactaact gtcacagtat acattggtaa taaaaacctt
     4141 tccccaa
//
