LOCUS       NM_001411298            3683 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus G protein-coupled receptor 61 (Gpr61), transcript
            variant 2, mRNA.
ACCESSION   NM_001411298 XM_017319559
VERSION     NM_001411298.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3683)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3683)
  AUTHORS   Xu,W., Nelson-Maney,N.P., Balint,L., Kwon,H.B., Davis,R.B.,
            Dy,D.C.M., Dunleavey,J.M., St Croix,B. and Caron,K.M.
  TITLE     Orphan G-Protein Coupled Receptor GPRC5B Is Critical for Lymphatic
            Development
  JOURNAL   Int J Mol Sci 23 (10), 5712 (2022)
   PUBMED   35628521
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3683)
  AUTHORS   Ghai,R., Bugarcic,A., Liu,H., Norwood,S.J., Skeldal,S.,
            Coulson,E.J., Li,S.S., Teasdale,R.D. and Collins,B.M.
  TITLE     Structural basis for endosomal trafficking of diverse transmembrane
            cargos by PX-FERM proteins
  JOURNAL   Proc Natl Acad Sci U S A 110 (8), E643-E652 (2013)
   PUBMED   23382219
REFERENCE   4  (bases 1 to 3683)
  AUTHORS   Nambu,H., Fukushima,M., Hikichi,H., Inoue,T., Nagano,N., Tahara,Y.,
            Nambu,T., Ito,J., Ogawa,Y., Ozaki,S. and Ohta,H.
  TITLE     Characterization of metabolic phenotypes of mice lacking GPR61, an
            orphan G-protein coupled receptor
  JOURNAL   Life Sci 89 (21-22), 765-772 (2011)
   PUBMED   21971119
  REMARK    GeneRIF: These findings suggest that GPR61 is involved in the
            regulation of food intake and body weight
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL671854.14.
            
            On Aug 24, 2022 this sequence version replaced XM_017319559.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK032627.1, SRR7345562.2971282.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-83                AL671854.14        98196-98278         c
            84-3683             AL671854.14        91720-95319         c
FEATURES             Location/Qualifiers
     source          1..3683
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 46.84 cM"
     gene            1..3683
                     /gene="Gpr61"
                     /note="G protein-coupled receptor 61"
                     /db_xref="GeneID:229714"
                     /db_xref="MGI:MGI:2441719"
     exon            1..83
                     /gene="Gpr61"
                     /inference="alignment:Splign:2.1.0"
     exon            84..3683
                     /gene="Gpr61"
                     /inference="alignment:Splign:2.1.0"
     CDS             684..2033
                     /gene="Gpr61"
                     /codon_start=1
                     /product="G-protein coupled receptor 61"
                     /protein_id="NP_001398227.1"
                     /db_xref="GeneID:229714"
                     /db_xref="MGI:MGI:2441719"
                     /translation="MESSPIPQSSGNSSTLGRALQTPGPSTASGVPELGLRDVASESV
                     ALFFMLLLDLTAVAGNAAVMAVIAKTPALRKFVFVFHLCLVDLLAALTLMPLAMLSSS
                     ALFDHALFGEVACRLYLFLSVCFVSLAILSVSAINVERYYYVVHPMRYEVRMTLGLVA
                     SVLVGVWVKALAMASVPVLGRVYWEEGAPSVNPGCSLQWSHSAYCQLFVVVFAVLYFL
                     LPLILIFVVYCSMFRVARVAAMQHGPLPTWMETPRQRSESLSSRSTMVTSSGAHQTTP
                     HRTFGGGKAAVVLLAVGGQFLLCWLPYFSFHLYVALSAQPISAGQVENVVTWIGYFCF
                     TSNPFFYGCLNRQIRGELSKQFVCFFKAAPEEELRLPSREGSIEENFLQFLQGTSENW
                     VSRPLPSPKREPPPVVDFRIPGQIAEETSEFLEQQLTSDIIMSDSYLRPAPSPRLES"
     regulatory      2050..2055
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gpr61"
                     /note="hexamer: AATAAA"
     polyA_site      2074
                     /gene="Gpr61"
                     /note="major polyA site"
     regulatory      3337..3342
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gpr61"
                     /note="hexamer: AATAAA"
     polyA_site      3360
                     /gene="Gpr61"
                     /note="major polyA site"
     regulatory      3666..3671
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gpr61"
                     /note="hexamer: AATAAA"
     polyA_site      3683
                     /gene="Gpr61"
ORIGIN      
        1 gcagtggttc aggcttcagc agccttggag aggcatcagc tgagaagagc tatcacatag
       61 gcgctgggag ctgctcagca aagatgcctt catgaggaaa ctggagtccg gaagagttgc
      121 agagtgagta atacccagac ctggaactag aagctgaatc tcatgctcct tctacttccc
      181 attctgatga gaaaatcaga aatttcacaa aatcaaccct aaagccagag cactgtccta
      241 gagcaaagca ggaccctgga gaggggagac aggaggattt agaattgccc tcagaaggga
      301 agaagaacaa ggagaactag gaaagaacga acatggagaa ctaaaaaaga aagtgagaaa
      361 agaggtgcca gaggtcactc ggaaggccac tgcagagtat gtgaggatcc tacacagtgc
      421 ttcccatcac cgggactgac cccggggcta ccttctgaca gaaactggac atgacctact
      481 gagtttggag cagcctggcc tggcactctg tctacatagg aacccagctt ggaaggctag
      541 tgattagagc ctgccttaca ggctccagaa ggccccccaa caaaattggg aagcctggac
      601 ctgggcttac atcccagggt tgtggagtag gatgggggat gggcctgtaa caggaagtgc
      661 cctgggtgtc ctctttcggc cccatggagt cctcacccat cccccagtca tcaggaaact
      721 cgtccacttt gggaagggcc cttcaaaccc caggtccctc tactgccagc ggggtcccag
      781 agttgggatt acgggacgtg gcttcagaat ctgtggccct cttcttcatg ctcctgttgg
      841 atctcactgc tgtggctggc aatgctgctg tgatggctgt tattgccaag acacccgccc
      901 tccgaaaatt tgtttttgtc ttccatcttt gtctggtgga cctgctggct gccctgaccc
      961 tcatgccgct tgccatgctc tccagctctg ccctctttga ccacgccctc tttggggagg
     1021 tggcctgccg cctctacctg ttcctgagcg tttgctttgt cagcctggcc atcctttcgg
     1081 tgtctgccat taatgtggag cgctactatt atgtggtcca cccaatgcgc tacgaggtgc
     1141 gcatgacact agggctggtg gcctccgtgc tggtgggcgt gtgggtaaag gccctagcca
     1201 tggcttctgt gccagtgttg ggaagggtct actgggagga aggagctccc agtgttaacc
     1261 ccggctgttc tctccaatgg agccatagtg cctactgcca gctttttgtg gtggtctttg
     1321 ctgttctgta cttcttgctg cccttgatcc tgatctttgt ggtctactgc agcatgtttc
     1381 gagtggctcg cgtggctgcc atgcaacacg ggccgctgcc cacgtggatg gagacgcccc
     1441 ggcaacgctc tgagtctctc agtagccgct ctactatggt taccagctcc ggggctcacc
     1501 agaccacccc acaccggacg tttgggggtg ggaaggcagc agtggtcctc ctggctgtag
     1561 ggggacagtt cttgctttgt tggttgccct acttctcttt ccatctctat gttgccctga
     1621 gcgcacagcc catttcagca ggacaggtgg agaacgtggt aacctggatt ggctactttt
     1681 gcttcacttc caaccccttt ttctacggat gtctcaaccg tcagatccgg ggcgagctta
     1741 gcaaacagtt tgtctgcttc ttcaaggcag ctccagagga ggagctgagg ctgcctagtc
     1801 gtgagggctc cattgaggag aatttcctgc agttcctcca ggggacctct gagaactggg
     1861 tttctcggcc cctacccagt cctaagcggg agccaccccc tgttgttgac tttcgaatcc
     1921 caggccagat tgctgaggag acctcagagt tcctggagca gcaactcacc agcgacatca
     1981 tcatgtccga cagctacctc cgtcccgccc cctcaccaag gctggagtca tgacggacac
     2041 caggagggaa ataaagcttg ggactggttt atgatttcaa ggactgcttt tgcggctggc
     2101 tggggtctgg gctagggtct ctggacttag cttttgcttg gtgtttcctg ggtcaggccc
     2161 agaatcgaca ggatggacat gtggcaaaaa gccttggact tggctgggat ctttgactat
     2221 tgggggaggg aacctgggta tggtgagacg ttgatgagag aaaagggtga caaaggtgag
     2281 ggaaagcctt tcttccagtg tactcttcag gcctcgggag acagggaaac ttcctaaggg
     2341 taggcggtgg agcagcaggc taggaacagt taatctgggg actgttgagg ttgacctctt
     2401 tccagagtag tagtccagac taatgcttac tctgagacaa ggtaagaaag cggcccacat
     2461 cttctcattt gccatctcgg caagtgtttc atgagttaac agatcccttc ctaaagttaa
     2521 tgtctagagt gagaagacct gtaggggtga attggatttg gccagcagca aggaaaaatt
     2581 gcaatcaggg tagtggagga gaagacagaa caactctgca actctctcct attctctttc
     2641 ctgcacatat gaaatcaagt gtgggtcctg acctcagcag agatgagcag gaggcaggat
     2701 gccctttccc tccttgtctt ttgagtaact aggaatgact cgggggtcag agagctgagg
     2761 gtgggtgtta gcctttgaat tggtaacgtg gctggataca gaaaggccag gtaaattact
     2821 ctgatcaata atactgccaa tcttttcttt ccaggactgg cctccccgat ctatctcctc
     2881 atggcagtga cccacttcca gccccctgga cattcgggta caagagactc aggtcgggca
     2941 agggaagggt ggggtttcca ttgtccatga aatgtctccc tgttccccat cattgctctc
     3001 aaaattagct tctgtgacaa agacttaaat ctgtctccta cctgcagccc taggttggag
     3061 agagagcaga gaattgggcc ttgctgctta ttgattaaga ctataggggc tgtgttggtt
     3121 agtatcagca atggtatttt cagcggaaag ggattaattg caagctggac aggtttcccc
     3181 tctgggtcct gttcattcca tttccctcaa ctgaatacta aagggtcaag gtagaaccag
     3241 agggggatgt gggctatagc tgaacaaatt tctggctcac tcaacatgaa agggggaaag
     3301 tgggttgggg tggagtagtt tcccctttga acaaccaata aattttatga taaaaagtta
     3361 tattaatatc aacactgact ccttcggttc tattcaatgc atgaatagct gaacaccaac
     3421 atcccccggg gcatacacat atgatgtgcc acctctgcct tcaaggactt cacaggctaa
     3481 ctcgaccaga tatttgtatt tttgtagagc atttaggtct gataaagtta tacagtaagg
     3541 aaaaattata tctatggttc tgacttttga gaatatattg aagttgatgc ataagagact
     3601 ccatgcagat gcggaaagtg tggggagtgt aagcaaaact ctctagggaa gaaaataatc
     3661 tactaaataa aactgggcaa aca
//
