LOCUS       NM_010338               3205 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus G protein-coupled receptor 37 (Gpr37), mRNA.
ACCESSION   NM_010338
VERSION     NM_010338.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3205)
  AUTHORS   Zhou,J., Xu,W., Wu,Y., Wang,M., Zhang,N., Wang,L., Feng,Y.,
            Zhang,T., Wang,L. and Mao,A.
  TITLE     GPR37 promotes colorectal cancer liver metastases by enhancing the
            glycolysis and histone lactylation via Hippo pathway
  JOURNAL   Oncogene 42 (45), 3319-3330 (2023)
   PUBMED   37749229
  REMARK    GeneRIF: GPR37 promotes colorectal cancer liver metastases by
            enhancing the glycolysis and histone lactylation via Hippo pathway.
REFERENCE   2  (bases 1 to 3205)
  AUTHORS   Bhattacharya,P., Dhawan,U.K., Hussain,M.T., Singh,P., Bhagat,K.K.,
            Singhal,A., Austin-Williams,S., Sengupta,S. and Subramanian,M.
  TITLE     Efferocytes release extracellular vesicles to resolve inflammation
            and tissue injury via prosaposin-GPR37 signaling
  JOURNAL   Cell Rep 42 (7), 112808 (2023)
   PUBMED   37436891
  REMARK    GeneRIF: Efferocytes release extracellular vesicles to resolve
            inflammation and tissue injury via prosaposin-GPR37 signaling.
REFERENCE   3  (bases 1 to 3205)
  AUTHORS   Kitamura,K., Homma,T., Sohel,M.S.H., Fuyuki,A., Miyawaki,S.,
            Onouchi,S. and Saito,S.
  TITLE     Expression patterns of prosaposin and its receptors, G
            protein-coupled receptor (GPR) 37 and GPR37L1, in the mouse
            olfactory organ
  JOURNAL   Tissue Cell 82, 102093 (2023)
   PUBMED   37075680
  REMARK    GeneRIF: Expression patterns of prosaposin and its receptors, G
            protein-coupled receptor (GPR) 37 and GPR37L1, in the mouse
            olfactory organ.
REFERENCE   4  (bases 1 to 3205)
  AUTHORS   Kumar,S., Vassallo,J.D., Nattamai,K.J., Hassan,A., Karns,R.,
            Vollmer,A., Soller,K., Sakk,V., Sacma,M., Nemkov,T.,
            D'Alessandro,A. and Geiger,H.
  TITLE     pH regulates hematopoietic stem cell potential via polyamines
  JOURNAL   EMBO Rep 24 (5), e55373 (2023)
   PUBMED   36943011
REFERENCE   5  (bases 1 to 3205)
  AUTHORS   Fuyuki,A., Yamamoto,S., Sohel,M.S.H., Homma,T., Kitamura,K.,
            Onouchi,S. and Saito,S.
  TITLE     Expression of prosaposin and its G protein-coupled receptor (GPR)
            37 in mouse cochlear and vestibular nuclei
  JOURNAL   J Vet Med Sci 85 (3), 266-270 (2023)
   PUBMED   36696997
  REMARK    GeneRIF: Expression of prosaposin and its G protein-coupled
            receptor (GPR) 37 in mouse cochlear and vestibular nuclei.
REFERENCE   6  (bases 1 to 3205)
  AUTHORS   Kitao,Y., Imai,Y., Ozawa,K., Kataoka,A., Ikeda,T., Soda,M.,
            Nakimawa,K., Kiyama,H., Stern,D.M., Hori,O., Wakamatsu,K., Ito,S.,
            Itohara,S., Takahashi,R. and Ogawa,S.
  TITLE     Pael receptor induces death of dopaminergic neurons in the
            substantia nigra via endoplasmic reticulum stress and dopamine
            toxicity, which is enhanced under condition of parkin inactivation
  JOURNAL   Hum Mol Genet 16 (1), 50-60 (2007)
   PUBMED   17116640
  REMARK    GeneRIF: Upregulation of Pael-R in the substantia nigra pars
            compacta of mice by retrograde infection induced endoplasmic
            reticulum (ER) stress leads to death of dopaminergic neurons.
REFERENCE   7  (bases 1 to 3205)
  AUTHORS   Nef,S., Schaad,O., Stallings,N.R., Cederroth,C.R., Pitetti,J.L.,
            Schaer,G., Malki,S., Dubois-Dauphin,M., Boizet-Bonhoure,B.,
            Descombes,P., Parker,K.L. and Vassalli,J.D.
  TITLE     Gene expression during sex determination reveals a robust female
            genetic program at the onset of ovarian development
  JOURNAL   Dev Biol 287 (2), 361-377 (2005)
   PUBMED   16214126
REFERENCE   8  (bases 1 to 3205)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   9  (bases 1 to 3205)
  AUTHORS   Marazziti,D., Golini,E., Mandillo,S., Magrelli,A., Witke,W.,
            Matteoni,R. and Tocchini-Valentini,G.P.
  TITLE     Altered dopamine signaling and MPTP resistance in mice lacking the
            Parkinson's disease-associated GPR37/parkin-associated
            endothelin-like receptor
  JOURNAL   Proc Natl Acad Sci U S A 101 (27), 10189-10194 (2004)
   PUBMED   15218106
REFERENCE   10 (bases 1 to 3205)
  AUTHORS   Marazziti,D., Gallo,A., Golini,E., Matteoni,R. and
            Tocchini-Valentini,G.P.
  TITLE     Molecular cloning and chromosomal localization of the mouse Gpr37
            gene encoding an orphan G-protein-coupled peptide receptor
            expressed in brain and testis
  JOURNAL   Genomics 53 (3), 315-324 (1998)
   PUBMED   9799598
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY723899.1, BB591616.1, BC031918.1 and BB184587.1.
            
            On Nov 14, 2007 this sequence version replaced NM_010338.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ223305.1, BC031918.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849376
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-116               BY723899.1         2-117
            117-132             BB591616.1         71-86
            133-3204            BC031918.1         1-3072
            3205-3205           BB184587.1         235-235
FEATURES             Location/Qualifiers
     source          1..3205
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 11.65 cM"
     gene            1..3205
                     /gene="Gpr37"
                     /gene_synonym="Pael-R"
                     /note="G protein-coupled receptor 37"
                     /db_xref="GeneID:14763"
                     /db_xref="MGI:MGI:1313297"
     exon            1..1868
                     /gene="Gpr37"
                     /gene_synonym="Pael-R"
                     /inference="alignment:Splign:2.1.0"
     exon            1869..3205
                     /gene="Gpr37"
                     /gene_synonym="Pael-R"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3122..3127
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gpr37"
                     /gene_synonym="Pael-R"
     regulatory      3178..3183
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gpr37"
                     /gene_synonym="Pael-R"
ORIGIN      
        1 atgcaccgct ccgcccgcca gcagcggttc caggcaccac gctctccacc cgggttgcga
       61 tggtggtggc agtgacaagc tcctgcagcc cacagcactg tgcacaaaac agcagcgccc
      121 tctcctccct ctcgctccac tccacgcctt ctcagcccgt gcactaggcg cagccgctgg
      181 cgccatccac ttgtcaactt tgaactgaag gagcagcaac tttgacagtg gccgcgggtt
      241 tcgaatctgg cttctccttg gcaacagtcc ctttgaaagt cgtcggagtt aaacgaagca
      301 agagtttcct ctgtgctccg gtggtgcctt gtttgcaagg gtccccaccc cccacccccc
      361 cgccagccga gagtgggatt gtgacagcca gtcccctagt ggagcggact tgtttttctt
      421 tttctctaga gacctctact agcgactgga taaagcagta tggaaaggat gtaaatagca
      481 gagcaactgt taccaagaag acagccacca cccaaaggct gggaggagcg cggggcttcc
      541 tccaggctgc gcccagtcgc aacattaggg aacaatcagg tggtgttcgc aacttttcaa
      601 ggtcagcctc ttggatctgt tatttccctg ggaaccttcg ggtgcaccga gcttggatta
      661 gatttggctg ggaaatgctc agaacatgaa acgtggaagg attgtaggga tgtgttgatg
      721 acaccgtcct tccccaagcg ccctgttccc tcccagcaat cttctgctcc catcctctac
      781 ccagcggtga gtatgtgaca tgtgcctaac tctctgcacc aagtttggca gcaggtgtcg
      841 gtgctaagct agagccaggc tagtaggtgc gccctcgccg agccatgcca gcccggggcg
      901 cgcctctctc gcgcacatcg cggctgctgc tccttctgct gtttaaggtt tctgtctctg
      961 ctgccctgag ctttgtccct gagcccagga atggaacttg tctgggggag agctgttccc
     1021 cactgatcca acgccgcagc agggatgccc gtggacctgg gaattcggca aaagacgctc
     1081 tgcgagtcca tgtgcccaga gagaaactgg aagcagaggt gagaggggcg acctcttggg
     1141 acctcccacc acccaggggc ggtgacacag gtgtgattga agaagcggcg gctgctgggc
     1201 ccttgggacc tccaaccaag ccaccaagtg cctggagatg gaaaagtgcc cagggtaaag
     1261 aaccatccgg gcatttgagg agaagggacc ccacggatcc ccaactcttc tttccgacat
     1321 cggagggggg agagatgagt tccaagcgcg atgggattcc ccagagcagg caggagcaca
     1381 gtgtgaaaac ggaacccaga gatctttttt actggccacg aagaactgga caactccagg
     1441 attcccaaca caggccttca gcagtacacg aaggaaggac ccttgctcct ccaggcaggg
     1501 cactaccgca aaacgggtct gcagatgact gggttcctga ccaagggggt ccacgccgtg
     1561 gaaacaccac gcggcgcgtg agattgaaga accccttcta cccattgacc caagaatcct
     1621 acggagccta tgcggtcatg tgcttatctg tggtgatctt tgggaccggc attattggca
     1681 acttggcagt gatgtgcatc gtgtgtcaca attactacat gaggagcatc tccaattctc
     1741 tcttggccaa cctggctttc tgggactttc tcatcatctt cttctgcctc cccctggtca
     1801 tcttccatga gttgactaag aagtggcttt tggaagattt ctcctgcaag atcgtgccct
     1861 atatcgaggt ggcttctctg ggtgtcacta ccttcacctt atgtgcactg tgcatagatc
     1921 gcttccgggc tgccaccaac gtccagatgt actatgaaat gattgaaaat tgctcttcca
     1981 ccactgccaa acttgccgtt atctgggttg gagctctgct tttggccctt ccggaagttg
     2041 tcctccgcca gctgagcaag gaagatttgg gctttagtgg ccaggctcct gcagaacggt
     2101 gtgtcataaa gatctctcct gatttaccgg acacaatcta tgttttggct ctcacctatg
     2161 atggtgcaag gctttggtgg tattttggct gctacttttg tctgcccaca cttttcacca
     2221 tcacctgctc tctagtgact gctcggaaga tccgcaaagc ggagaaggcc agtacccgtg
     2281 gaaacaagcg gcagatccat ctagagagcc agatgaactg cacagtggtg gctctgacca
     2341 ttttatatgg gttttgcatc atccctgaga atatctgcaa cattgtcact gcctacatgg
     2401 ccacgggcgt ctctcagcag accatggacc tgctcaacat catcagccag ttccttttgt
     2461 ttttcaagtc ctgtgtcacc cccgtgctcc tcttctgcct ctgcagaccc ttcagcaggg
     2521 ccttcatgga gtgctgctgc tgctgctgtg aggagtgtat ccagaagtct tccactgtga
     2581 ccagtgacga caacgacaac gagtacacca cagagctgga gctgtcgccc ttcagtacta
     2641 tccgcaggga gatgtccact tttgcttctg tggggactca ttgctgaagg aacggcttgg
     2701 ttagctctga tttcttcgat tttcatattc tgtgaaaatt tttactccat atttttcctt
     2761 acaggggaac aatgcacaca ttttgaaaag caagtagagg aagacatatt aactactcta
     2821 gaactgattt tgcaaattaa tatttgtgct ctgggaaaaa atgtttctat ttagttatgt
     2881 aagaagaagg aggccaacag tctcagatca tttttttctg ctatggtgct aatattttat
     2941 tcaaaagtta ttgcacctta acaatattaa ttgtttgatt tctttctttc ttttaaaaac
     3001 ataatcgttg tatattgaag gcaggcccgg gattttgcta gttattttgt gtttgagttg
     3061 tgattggaag tacattgtat ttgaaatggt ttgttttttc cagccatgca acttagcacc
     3121 aaataaactt ctcatccttc tttaatatga ctgtcaatct acttttaacc aagactcaat
     3181 aaatttttta attgccttaa ataac
//
