LOCUS       NM_173410               2799 bp    mRNA    linear   ROD 06-APR-2024
DEFINITION  Mus musculus G protein-coupled receptor 26 (Gpr26), mRNA.
ACCESSION   NM_173410
VERSION     NM_173410.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2799)
  AUTHORS   Liu,F., Yang,W., Hu,M., Zhang,Y., Sun,B., Yang,H., Brosius,J. and
            Deng,C.
  TITLE     Constitutive activity of GPR26 regulated by ubiquitin-dependent
            degradation and its antitumor role
  JOURNAL   FEBS J 288 (15), 4655-4682 (2021)
   PUBMED   33577134
  REMARK    GeneRIF: Constitutive activity of GPR26 regulated by
            ubiquitin-dependent degradation and its antitumor role.
REFERENCE   2  (bases 1 to 2799)
  AUTHORS   Monteiro,F.A., Miranda,R.M., Samina,M.C., Dias,A.F.,
            Raposo,A.A.S.F., Oliveira,P., Reguenga,C., Castro,D.S. and Lima,D.
  TITLE     Tlx3 Exerts Direct Control in Specifying Excitatory Over Inhibitory
            Neurons in the Dorsal Spinal Cord
  JOURNAL   Front Cell Dev Biol 9, 642697 (2021)
   PUBMED   33996801
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2799)
  AUTHORS   Mattiske,T., Lee,K., Gecz,J., Friocourt,G. and Shoubridge,C.
  TITLE     Embryonic forebrain transcriptome of mice with polyalanine
            expansion mutations in the ARX homeobox gene
  JOURNAL   Hum Mol Genet 25 (24), 5433-5443 (2016)
   PUBMED   27798109
REFERENCE   4  (bases 1 to 2799)
  AUTHORS   Thompson,C.L., Ng,L., Menon,V., Martinez,S., Lee,C.K.,
            Glattfelder,K., Sunkin,S.M., Henry,A., Lau,C., Dang,C.,
            Garcia-Lopez,R., Martinez-Ferre,A., Pombero,A., Rubenstein,J.L.R.,
            Wakeman,W.B., Hohmann,J., Dee,N., Sodt,A.J., Young,R., Smith,K.,
            Nguyen,T.N., Kidney,J., Kuan,L., Jeromin,A., Kaykas,A., Miller,J.,
            Page,D., Orta,G., Bernard,A., Riley,Z., Smith,S., Wohnoutka,P.,
            Hawrylycz,M.J., Puelles,L. and Jones,A.R.
  TITLE     A high-resolution spatiotemporal atlas of gene expression of the
            developing mouse brain
  JOURNAL   Neuron 83 (2), 309-323 (2014)
   PUBMED   24952961
REFERENCE   5  (bases 1 to 2799)
  AUTHORS   Buniello,A., Hardisty-Hughes,R.E., Pass,J.C., Bober,E., Smith,R.J.
            and Steel,K.P.
  TITLE     Headbobber: a combined morphogenetic and cochleosaccular mouse
            model to study 10qter deletions in human deafness
  JOURNAL   PLoS One 8 (2), e56274 (2013)
   PUBMED   23457544
REFERENCE   6  (bases 1 to 2799)
  AUTHORS   Somma,G., Alger,H.M., McGuire,R.M., Kretlow,J.D., Ruiz,F.R.,
            Yatsenko,S.A., Stankiewicz,P., Harrison,W., Funk,E.,
            Bergamaschi,A., Oghalai,J.S., Mikos,A.G., Overbeek,P.A. and
            Pereira,F.A.
  TITLE     Head bobber: an insertional mutation causes inner ear defects,
            hyperactive circling, and deafness
  JOURNAL   J Assoc Res Otolaryngol 13 (3), 335-349 (2012)
   PUBMED   22383091
REFERENCE   7  (bases 1 to 2799)
  AUTHORS   Chen,D., Liu,X., Zhang,W. and Shi,Y.
  TITLE     Targeted inactivation of GPR26 leads to hyperphagia and adiposity
            by activating AMPK in the hypothalamus
  JOURNAL   PLoS One 7 (7), e40764 (2012)
   PUBMED   22815809
  REMARK    GeneRIF: These findings identified a key role of GPR26 as a central
            regulator of energy homeostasis though modulation of hypothalamic
            AMPK activation.
            Erratum:[PLoS One. 2012;7(8):
            doi/10.1371/annotation/3629b4c2-4810-4bbd-ae13-53d3d01bce60]
REFERENCE   8  (bases 1 to 2799)
  AUTHORS   Zhang,L.L., Wang,J.J., Liu,Y., Lu,X.B., Kuang,Y., Wan,Y.H.,
            Chen,Y., Yan,H.M., Fei,J. and Wang,Z.G.
  TITLE     GPR26-deficient mice display increased anxiety- and depression-like
            behaviors accompanied by reduced phosphorylated cyclic AMP
            responsive element-binding protein level in central amygdala
  JOURNAL   Neuroscience 196, 203-214 (2011)
   PUBMED   21924326
  REMARK    GeneRIF: data indicate that Gpr26 is important for emotion
            regulation in mice, a function probably mediated by the
            phosphorylation of CREB in the central amygdala.
REFERENCE   9  (bases 1 to 2799)
  AUTHORS   Jones,P.G., Nawoschik,S.P., Sreekumar,K., Uveges,A.J., Tseng,E.,
            Zhang,L., Johnson,J., He,L., Paulsen,J.E., Bates,B. and Pausch,M.H.
  TITLE     Tissue distribution and functional analyses of the constitutively
            active orphan G protein coupled receptors, GPR26 and GPR78
  JOURNAL   Biochim Biophys Acta 1770 (6), 890-901 (2007)
   PUBMED   17363172
REFERENCE   10 (bases 1 to 2799)
  AUTHORS   Vassilatis,D.K., Hohmann,J.G., Zeng,H., Li,F., Ranchalis,J.E.,
            Mortrud,M.T., Brown,A., Rodriguez,S.S., Weller,J.R., Wright,A.C.,
            Bergmann,J.E. and Gaitanaris,G.A.
  TITLE     The G protein-coupled receptor repertoires of human and mouse
  JOURNAL   Proc Natl Acad Sci U S A 100 (8), 4903-4908 (2003)
   PUBMED   12679517
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC105062.13.
            
            On May 2, 2007 this sequence version replaced NM_173410.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK036100.1, BC119380.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849383, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1136              AC105062.13        25717-26852         c
            1137-1250           AC105062.13        18922-19035         c
            1251-2799           AC105062.13        7679-9227           c
FEATURES             Location/Qualifiers
     source          1..2799
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 75.28 cM"
     gene            1..2799
                     /gene="Gpr26"
                     /gene_synonym="9630036A11Rik; A730021D22"
                     /note="G protein-coupled receptor 26"
                     /db_xref="GeneID:233919"
                     /db_xref="MGI:MGI:2441758"
     exon            1..1136
                     /gene="Gpr26"
                     /gene_synonym="9630036A11Rik; A730021D22"
                     /inference="alignment:Splign:2.1.0"
     CDS             469..1482
                     /gene="Gpr26"
                     /gene_synonym="9630036A11Rik; A730021D22"
                     /codon_start=1
                     /product="G-protein coupled receptor 26"
                     /protein_id="NP_775586.1"
                     /db_xref="CCDS:CCDS21920.1"
                     /db_xref="GeneID:233919"
                     /db_xref="MGI:MGI:2441758"
                     /translation="MNSWDAGLAGLLVGTIGVSLLSNGLVLLCLLHSADIRRQAPALF
                     TLNLTCGNLLCTVVNMPLTLAGVVAQRQPAGDRLCRLAAFLDTFLAANSMLSMAALSI
                     DRWVAVVFPLSYRAKMRLRDAAFMVAYTWLHALTFPATALALSWLGFHQLYASCTLCS
                     RRPDERLRFAVFTSAFHALSFLLSFIVLCFTYLKVLKVARFHCKRIDVITMQTLVLLV
                     DIHPSVRERCLEEQKRRRQRATKKISTFIGTFLVCFAPYVITRLVELFSTAPIGSHWG
                     VLSKCLAYSKAASDPFVYSLLRHQYRRSCKELLNRIFNRRSLHSVGLTGDSHSQNILP
                     VSE"
     exon            1137..1250
                     /gene="Gpr26"
                     /gene_synonym="9630036A11Rik; A730021D22"
                     /inference="alignment:Splign:2.1.0"
     exon            1251..2799
                     /gene="Gpr26"
                     /gene_synonym="9630036A11Rik; A730021D22"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gacagagaga aagccacaaa gcagaagggt gtgcggagca gagccagagc tgagagggac
       61 ccagtaaggg cgggtgcagg cagacgcaaa gccagtgacc acaggagact gcgaccccgg
      121 attccagggc acttcaggag gtcagaggag cacaggccaa gaggtggtgc gggactggga
      181 gtgaacactc gcctaggtga tcgccggtga ggtgacccca gactccgagt ggttccgtgc
      241 ccaggtgctc gcctgggagg tggcgcgggg ctccgggagg ctgcgtgcct aggtgctggc
      301 ccagggggtg gcgcgggctt ctgggttggt ggatgccctc tgggtagcca tggcgacaag
      361 ggccaggggt cgctgggctg ccgtgtcgcc taggggctga gtcgacagca ggctgcgcca
      421 tggcggcgcg gggttgcggg ccctgagcgc cagcggcggg cgcgcaccat gaactcgtgg
      481 gacgcgggcc tggcggggct gctggtgggc actatcggcg tgtcgctgct gtccaacggg
      541 ctggtgctgc tctgcctcct gcacagcgct gacatccgcc gccaggcgcc ggcgctcttc
      601 actctcaacc tcacgtgtgg caacctgctg tgtaccgtgg tcaacatgcc actaacactg
      661 gccggcgtcg tggcacaacg gcagccggcc ggggaccgcc tgtgccgcct ggccgccttc
      721 ctcgacacct ttctggccgc caactccatg ctcagcatgg ccgcgctcag catcgaccgc
      781 tgggtggctg tggtctttcc gctgagctac cgtgccaaga tgcgcctccg agatgccgcc
      841 ttcatggtgg cctacacgtg gctgcacgcg ctcaccttcc cggccaccgc gctcgccctg
      901 tcctggctcg gcttccacca gctatatgcc tcgtgcacac tgtgcagccg gcggccggac
      961 gagcgcctgc gctttgctgt cttcaccagc gccttccatg cgctcagctt cctgctctcc
     1021 ttcatcgtgc tctgcttcac gtacctcaag gtgctcaagg tggcccgctt ccactgcaag
     1081 cgcatcgacg tgatcaccat gcagacgctt gtgctgttgg tggacataca ccccagtgtg
     1141 agggaacggt gtctggagga acagaagcgg aggcgacagc gtgccaccaa gaagatcagc
     1201 accttcatag ggaccttcct tgtgtgcttt gcaccctatg tgattaccag gctggtggaa
     1261 ctcttctcca cagcacccat tggctctcac tggggagtgc tgtccaagtg cttggcctac
     1321 agcaaggccg cttctgaccc cttcgtgtat tccttgctgc gacaccaata ccgcaggagc
     1381 tgcaaggagc tcctgaacag gatcttcaac agacgctccc ttcactctgt gggcctcaca
     1441 ggtgactctc acagccagaa cattctgcca gtgtcggaat gaaggaccac tctcctgatg
     1501 gggagttcag aacgaggtgg ccagagcaaa gggaggtggt ctgggactcc tgggtggaca
     1561 ataactgcca ccattgcctg gtgattgccg tgatgctgac gtctgaacaa gatctggggc
     1621 ctgcttcttg gctcttccag ggtagatgtc agactgtccc tatttgtcgc caaaggatgg
     1681 ccataggcca cgccctggcc tttctttctg agagtgtgta ttgagagctt agactcacca
     1741 aaggcctctc agaggacggt aggccagtta gtgtcaaaga cacagagtgc tggtggcagg
     1801 tgtgggcatg atatccacct gtctactaac tactgctcat ggggctccat gctccaaggg
     1861 acatcttagt gatgctgaaa gtgaggttgt ctgtggccat ctggctccag atctactatg
     1921 gcatctcttt tccccttggt agtgtttgct gctgtaaccc aaatattatc cagctggtgc
     1981 caactacatc atgatcagct gatacccttg ggccctgcac tcaatgggaa catgtttaac
     2041 aaccagtttg ctacctacca gttgtcttag gaatgataaa ttggactcac cttttgtccc
     2101 tctttcatca aactaatgtt tgcgtgtatt gacaatctta gcatgaaagt ggtctctcgg
     2161 tagacaggtc ttagataatg ttagattcca tgaaatctga gcaggaagtc accttctgat
     2221 ttgcatgcca taggtaaagg agcccaggaa agtaggaaga tggtggctgg tctgtcctac
     2281 ctccatatct gggatctgag ttggtaggga agacttcctc ttgtcttaga catcttgcct
     2341 gtcatattct aggagctgac ttgaacaggg atgaagtctt agttttcaga tactgggctc
     2401 tattatcctg gtggctcatt acccacattc tgcaactttg tcctgagaaa gcagcagcta
     2461 tccaaggtca ccacaaaagt gctctgtgcc actgatgaga gagtgcagtt agtacaagat
     2521 gctgttcctg taatatacat gccaatccat tgggagccat tgtcttagtc tcattgaaaa
     2581 ctaagataag gacaggagaa atagcttagc cagtaaagtg cttactgtgc aagcatgaag
     2641 gcctgagtcc aaccccaaga gcccaaatta aaagcaaact ggacatggtg gtgtgcacct
     2701 gtaatcctag cactggagaa tcgagagagg cgactccaca ggacttaggt cagccaagac
     2761 ttagctgaat gggtgagcta caggccagtg acggtcctg
//
