LOCUS       NM_001409840            3277 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus G protein-coupled receptor 162 (Gpr162), transcript
            variant 5, mRNA.
ACCESSION   NM_001409840 XM_006505555
VERSION     NM_001409840.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3277)
  AUTHORS   Shah,K., King,G.D. and Jiang,H.
  TITLE     A chromatin modulator sustains self-renewal and enables
            differentiation of postnatal neural stem and progenitor cells
  JOURNAL   J Mol Cell Biol 12 (1), 4-16 (2020)
   PUBMED   31065682
REFERENCE   2  (bases 1 to 3277)
  AUTHORS   Caruso,V., Hagglund,M.G., Badiali,L., Bagchi,S., Roshanbin,S.,
            Ahmad,T., Schioth,H.B. and Fredriksson,R.
  TITLE     The G protein-coupled receptor GPR162 is widely distributed in the
            CNS and highly expressed in the hypothalamus and in hedonic feeding
            areas
  JOURNAL   Gene 553 (1), 1-6 (2014)
   PUBMED   25275856
  REMARK    GeneRIF: GPR162 is widely expressed in GABAergic as well as other
            neurons within the mouse hippocampus, whereas extensive expression
            is observed in areas related to energy homeostasis and hedonic
            feeding such as hypothalamus, amygdala and ventral tegmental area
REFERENCE   3  (bases 1 to 3277)
  AUTHORS   Gloriam,D.E., Schioth,H.B. and Fredriksson,R.
  TITLE     Nine new human Rhodopsin family G-protein coupled receptors:
            identification, sequence characterisation and evolutionary
            relationship
  JOURNAL   Biochim Biophys Acta 1722 (3), 235-246 (2005)
   PUBMED   15777626
REFERENCE   4  (bases 1 to 3277)
  AUTHORS   Ansari-Lari,M.A., Oeltjen,J.C., Schwartz,S., Zhang,Z., Muzny,D.M.,
            Lu,J., Gorrell,J.H., Chinault,A.C., Belmont,J.W., Miller,W. and
            Gibbs,R.A.
  TITLE     Comparative sequence analysis of a gene-rich cluster at human
            chromosome 12p13 and its syntenic region in mouse chromosome 6
  JOURNAL   Genome Res 8 (1), 29-40 (1998)
   PUBMED   9445485
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC142254.4.
            
            On Jul 22, 2022 this sequence version replaced XM_006505555.5.
            
            Transcript Variant: This variant (5) represents the longest
            transcript and encodes the longer isoform (a). Variants 1-5 all
            encode the same isoform (a).
            
            ##Evidence-Data-START##
            CDS exon combination :: SRR7345562.2486499.1, SRR9219382.201507.1
                                    [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMN01164131 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-267               AC142254.4         70107-70373
            268-384             AC142254.4         71019-71135
            385-2152            AC142254.4         71458-73225
            2153-2342           AC142254.4         73832-74021
            2343-2500           AC142254.4         74395-74552
            2501-3277           AC142254.4         74824-75600
FEATURES             Location/Qualifiers
     source          1..3277
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 59.17 cM"
     gene            1..3277
                     /gene="Gpr162"
                     /gene_synonym="A-2; Grca"
                     /note="G protein-coupled receptor 162"
                     /db_xref="GeneID:14788"
                     /db_xref="MGI:MGI:1315214"
     exon            1..267
                     /gene="Gpr162"
                     /gene_synonym="A-2; Grca"
                     /inference="alignment:Splign:2.1.0"
     exon            268..384
                     /gene="Gpr162"
                     /gene_synonym="A-2; Grca"
                     /inference="alignment:Splign:2.1.0"
     exon            385..2152
                     /gene="Gpr162"
                     /gene_synonym="A-2; Grca"
                     /inference="alignment:Splign:2.1.0"
     CDS             1286..3052
                     /gene="Gpr162"
                     /gene_synonym="A-2; Grca"
                     /EC_number="1.14.11.7"
                     /note="isoform a is encoded by transcript variant 5; gene
                     rich cluster, A; probable G-protein coupled receptor 162"
                     /codon_start=1
                     /product="probable G-protein coupled receptor 162 isoform
                     a"
                     /protein_id="NP_001396769.1"
                     /db_xref="GeneID:14788"
                     /db_xref="MGI:MGI:1315214"
                     /translation="MARGGLGAEEASLRSNALSWLACGLLALLANAWIILSISAKQQK
                     HKPLELLLCFLAGTHILMAAVPLTTFAVVQLRRQASSDYDWNESICKVFVSTYYTLAL
                     ATCFTVASLSYHRMWMVRWPVNYRLSNAKKQALHAVMGIWMVSFILSTLPSIGWHNNG
                     ERYYARGCQFIVSKIGLGFGVCFSLLLLGGIVMGLVCVAITFYQTLWARPRRARQARR
                     AGGSVGTKAGGLGGLGTRPAFEVPAIVVEDTRGKRRSSLDGSESAKTSLQVTNLVSAI
                     VFLYDSLTGVPILVVSFFSLKSDSAPPWMVLAVLWCSMAQTLLLPSFIWSCERYRADV
                     RTVWEQCVAIMSEDDGDDDGTCDDYTDGRVCKIRFDANGATGSGSRDPTQVKLLPGRH
                     MLFPPLERVHYLQVPLSRRLSHDETNIFSTPRAPGSFLHKWSSSDDIRILPAQSRALG
                     GPPEYLGQRHRLEDEEDEEEAEGGGLASLRQFLESGVLGSGGGPPRGPGFFREEITTF
                     IDETPLPSPTASPGPSPRRPRPLGFSPRRLSLGSPDSRAVGLPLGLSAGRRCSLTGSE
                     GSSRAWGRPWGPGNPIFPQLTL"
     exon            2153..2342
                     /gene="Gpr162"
                     /gene_synonym="A-2; Grca"
                     /inference="alignment:Splign:2.1.0"
     exon            2343..2500
                     /gene="Gpr162"
                     /gene_synonym="A-2; Grca"
                     /inference="alignment:Splign:2.1.0"
     exon            2501..3277
                     /gene="Gpr162"
                     /gene_synonym="A-2; Grca"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3252..3257
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gpr162"
                     /gene_synonym="A-2; Grca"
                     /note="hexamer: ATTAAA"
     polyA_site      3277
                     /gene="Gpr162"
                     /gene_synonym="A-2; Grca"
                     /note="major polyA site"
ORIGIN      
        1 accctcgcca cccccgaccc caagactggt cagcggctcc ctaaccccgg gctcgcaggc
       61 tgatgaccct gggagacagg ggcctcgagg ggccgcaaac tagcgcgccg cgggctgagc
      121 ccgagaggcc aggctggggg gagggaggcc cggagggagg gagtgaagga aggaggaggg
      181 ctggcgagct ggagccggca ggcggcggga gcccgggcga gcctcgtcgg gagtgcgtct
      241 cctcggcaga gcaggacgca gccagagtgc cttccccagc tctccctgaa ccgtatcact
      301 aagaccagaa ccctcctgct ctctcccatc agagggaaac tgaggctctg gaccagggga
      361 ggagacccaa agtctcctag tgaggtagct gaaggggtga aaacccaggc ttagataagt
      421 aggctgagca caaagaccac aaagtccagg agaatggcat gcaggagaag ggctcctgct
      481 ttaatgtgag tccccaagga ggaacacatc acactgtctg tctcccatta gcaactgaag
      541 agagacctag ggacatggag acagggctgg gtagttctga gcatgggcta ttataagcac
      601 aaaacttgga attccaaagc agggagaaaa ggctaaaagg aatggagacc cttccatgta
      661 gtctgcaagt agatgaggtc ttatgcctgt gggtaagggg gcatctgact taaggcaagg
      721 gaatgctctg aatgacccca gcgaccctca gcatcagtca tttccatagt ttcaagggaa
      781 agggggtaca agtgagccaa gcacagcaca ggcctaatgc ttgctcctca tctcatcctc
      841 cctcacagct tgtccaggtg actgagctcc acccctgtgc accaagacac ccaccccacc
      901 ccccactggt caagcctcgc tggagaaaga gaccgggaag tcccagcatg agaatcagag
      961 ctgcccagcc agcttcatag atggggaagc agcctgcttg cctcccccat caattacagg
     1021 gataactgag aaaaagcccc acccaatatg gaggctgagg actaccgcct ctattaattc
     1081 cctgccttct cccctgccct gcccacctgg ccttagctgg gtcactcatg caatgctgag
     1141 aagtaagcaa gacttggggt cagcttgcct ggctaccagg caaggactgt gggcatcatg
     1201 ggggtgtgtg tgagcggggc tccagggtga gacctagccc ccgcccccag gaattcaagg
     1261 gggtgggggt ggggccgagg atagaatggc tcggggaggg ttgggggcag aagaggcctc
     1321 cctacgctca aacgcattgt cctggctggc ctgtgggctc ctggccctgc tggccaacgc
     1381 ttggatcatc cttagcatct cagccaaaca gcagaaacac aagccactgg agttactgct
     1441 ctgcttcctg gccggtactc atatactcat ggcggctgtg ccccttacca cctttgctgt
     1501 ggtgcagctc cggcgccagg cttcctctga ctatgactgg aacgagagca tctgcaaggt
     1561 ctttgtgtcc acctactaca cgctggccct ggccacctgc ttcacggtcg cctcgctctc
     1621 ctaccatcgc atgtggatgg tgcgatggcc cgttaactac cgcctcagca acgccaagaa
     1681 gcaggcgctg catgccgtca tgggcatctg gatggtcagc ttcatcctct ccacgctgcc
     1741 ctccatcggc tggcacaaca acggggagcg ctactatgcc cgaggctgcc agttcatagt
     1801 ctccaagatc ggcctcggtt ttggtgtctg cttcagcctc ctgcttcttg ggggcattgt
     1861 catggggttg gtctgtgtgg ctatcacatt ctatcagaca ctgtgggccc ggccccggag
     1921 ggctcggcag gcccggagag cggggggcag tgtgggcacc aaagcagggg ggctgggggg
     1981 gttgggtacc cggccagctt ttgaggtgcc agccattgtg gtggaggata ctcgagggaa
     2041 gcggcggtcc tcgctggatg gctctgaatc tgccaagaca tccttgcagg tcaccaactt
     2101 ggtcagcgcc atcgtctttc tctatgactc actcacgggg gtgcccattt tggtggtgag
     2161 cttcttctcc ttgaagtcag actcagctcc gccatggatg gtgttggcag tgctgtggtg
     2221 ctccatggca cagacactgc tcctgccctc cttcatctgg tcctgtgagc gctaccgtgc
     2281 agatgtgcgc acagtgtggg agcagtgtgt ggcgatcatg tccgaggatg acggtgatga
     2341 cgatggcacc tgtgacgact acacagatgg ccgagtgtgc aaaattcgct ttgatgctaa
     2401 cggggccaca gggtcaggga gtcgggaccc cacccaggtg aagctgctgc ctgggcggca
     2461 catgctcttc ccaccgctgg agagagtaca ctacttacag gtccctttgt cccgacgatt
     2521 atcccacgat gagaccaaca tcttttctac tcctcgggca ccaggctcct tcctgcacaa
     2581 gtggtcctca tcggatgata tccggatcct cccagcccag agccgagccc tcggaggccc
     2641 tccagaatac ctgggacaga gacacaggct ggaggatgag gaggatgagg aagaggctga
     2701 aggcgggggc ttggccagcc ttcgacagtt tctagaaagt ggggttctgg ggtcgggtgg
     2761 gggaccccca cgaggtcccg gttttttccg ggaggagatc accaccttca tcgatgagac
     2821 acctctgcct tctccaactg cgtcaccagg accctctcct cgtaggccta gaccactggg
     2881 tttttcacct cgacggctct cccttgggtc tccggatagc cgagccgttg gacttccttt
     2941 ggggttaagt gcaggaagac gctgttccct gaccgggagc gaagggagtt caagggcttg
     3001 gggaagaccc tgggggccag gtaaccccat cttcccccag ttgaccctgt gaggccgcat
     3061 aggcctgctt cactggaggg gggggggagg cacgagcgag tgagtatgcc tcatcctggc
     3121 cctgagtcta tggcagctgc ctccagggag atgggggggg gggggcctac atccgggctc
     3181 tagagcccca gctctctccc atccaagtga ccagataccc aacgcacccg tcttcacccc
     3241 tagcaaaatg tattaaaagg ctgagttgcc gtggaaa
//
