LOCUS       NM_001134385            2208 bp    mRNA    linear   ROD 19-NOV-2024
DEFINITION  Mus musculus G protein-coupled receptor 160 (Gpr160), transcript
            variant 1, mRNA.
ACCESSION   NM_001134385 XM_130823 XM_896590 XM_921004 XM_921012 XM_977547
            XM_980080
VERSION     NM_001134385.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2208)
  AUTHORS   Fan,S., Guo,C., Yang,G., Hong,L., Li,H., Ma,J., Zhou,Y., Fan,S.,
            Xue,Y. and Zeng,F.
  TITLE     GPR160 regulates the self-renewal and pluripotency of mouse
            embryonic stem cells via JAK1/STAT3 signaling pathway
  JOURNAL   J Genet Genomics 51 (10), 1055-1065 (2024)
   PUBMED   38750952
  REMARK    GeneRIF: GPR160 regulates the self-renewal and pluripotency of
            mouse embryonic stem cells via JAK1/STAT3 signaling pathway.
REFERENCE   2  (bases 1 to 2208)
  AUTHORS   Schafer,R.M., Giancotti,L.A., Davis,D.J., Larrea,I.G., Farr,S.A.
            and Salvemini,D.
  TITLE     Behavioral characterization of G-protein-coupled receptor 160
            knockout mice
  JOURNAL   Pain 165 (6), 1361-1371 (2024)
   PUBMED   38198232
  REMARK    GeneRIF: Behavioral characterization of G-protein-coupled receptor
            160 knockout mice.
REFERENCE   3  (bases 1 to 2208)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   4  (bases 1 to 2208)
  AUTHORS   Yang,H., Liu,H., Chen,H., Mo,H., Chen,J., Huang,X., Zheng,R.,
            Liu,Z., Feng,Y., Liu,F. and Ge,B.
  TITLE     G protein-coupled receptor160 regulates mycobacteria entry into
            macrophages by activating ERK
  JOURNAL   Cell Signal 28 (9), 1145-1151 (2016)
   PUBMED   27259691
  REMARK    GeneRIF: these findings suggest an important role of GPR160 in
            regulating the entry of BCG into macrophages by targeting the ERK
            signaling pathway.
REFERENCE   5  (bases 1 to 2208)
  AUTHORS   Zhou,C., Dai,X., Chen,Y., Shen,Y., Lei,S., Xiao,T., Bartfai,T.,
            Ding,J. and Wang,M.W.
  TITLE     G protein-coupled receptor GPR160 is associated with apoptosis and
            cell cycle arrest of prostate cancer cells
  JOURNAL   Oncotarget 7 (11), 12823-12839 (2016)
   PUBMED   26871479
REFERENCE   6  (bases 1 to 2208)
  AUTHORS   Ghai,R., Bugarcic,A., Liu,H., Norwood,S.J., Skeldal,S.,
            Coulson,E.J., Li,S.S., Teasdale,R.D. and Collins,B.M.
  TITLE     Structural basis for endosomal trafficking of diverse transmembrane
            cargos by PX-FERM proteins
  JOURNAL   Proc Natl Acad Sci U S A 110 (8), E643-E652 (2013)
   PUBMED   23382219
REFERENCE   7  (bases 1 to 2208)
  AUTHORS   Ding,S., Wu,X., Li,G., Han,M., Zhuang,Y. and Xu,T.
  TITLE     Efficient transposition of the piggyBac (PB) transposon in
            mammalian cells and mice
  JOURNAL   Cell 122 (3), 473-483 (2005)
   PUBMED   16096065
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC158135.5 and AC111093.10.
            
            On Nov 30, 2013 this sequence version replaced NM_001134385.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC116649.1, SRR1660813.72422.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-296               AC158135.5         183767-184062
            297-623             AC111093.10        34140-34466
            624-723             AC111093.10        46847-46946
            724-2208            AC111093.10        52615-54099
FEATURES             Location/Qualifiers
     source          1..2208
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 14.33 cM"
     gene            1..2208
                     /gene="Gpr160"
                     /gene_synonym="1700025D19Rik; GPCR150"
                     /note="G protein-coupled receptor 160"
                     /db_xref="GeneID:71862"
                     /db_xref="MGI:MGI:1919112"
     exon            1..296
                     /gene="Gpr160"
                     /gene_synonym="1700025D19Rik; GPCR150"
                     /inference="alignment:Splign:2.1.0"
     exon            297..623
                     /gene="Gpr160"
                     /gene_synonym="1700025D19Rik; GPCR150"
                     /inference="alignment:Splign:2.1.0"
     exon            624..723
                     /gene="Gpr160"
                     /gene_synonym="1700025D19Rik; GPCR150"
                     /inference="alignment:Splign:2.1.0"
     exon            724..2208
                     /gene="Gpr160"
                     /gene_synonym="1700025D19Rik; GPCR150"
                     /inference="alignment:Splign:2.1.0"
     CDS             795..1805
                     /gene="Gpr160"
                     /gene_synonym="1700025D19Rik; GPCR150"
                     /codon_start=1
                     /product="probable G-protein coupled receptor 160"
                     /protein_id="NP_001127857.1"
                     /db_xref="CCDS:CCDS50883.1"
                     /db_xref="GeneID:71862"
                     /db_xref="MGI:MGI:1919112"
                     /translation="MTALSSKNCSLQYQLHQSPQLLEASCLLFLIILGKVLLNILLLR
                     VRRGDARWTLMEYFCFSLALVDLLLLVNISILTYFRDFVVLGIRFTRYHICLLTQIIS
                     FTYGFLHYPVCSLACIDYWCNLSRASKQSSRWQKLLYFLTVILTWISVLAYVLVDPAI
                     SVSLKAHRGYVYQCPAYVSTQSHWLSLSMLMVLFVAFLISWQEVVALLQAMRIASYKS
                     KAALYFPFPLHCGYALSCREALLPRLIVCFLGTWFPFVALQVLILSLRVQIPAYIEMN
                     VPWLYFVNSFLIAAVYWFNCHKLDLRDSSLPVDPFINWKCCFVPVHRLKQVERPMSIV
                     IC"
     regulatory      2086..2091
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gpr160"
                     /gene_synonym="1700025D19Rik; GPCR150"
                     /note="hexamer: TATAAA"
     polyA_site      2117
                     /gene="Gpr160"
                     /gene_synonym="1700025D19Rik; GPCR150"
     regulatory      2183..2188
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gpr160"
                     /gene_synonym="1700025D19Rik; GPCR150"
                     /note="hexamer: AATAAA"
     polyA_site      2204
                     /gene="Gpr160"
                     /gene_synonym="1700025D19Rik; GPCR150"
                     /note="major polyA site"
ORIGIN      
        1 ggggcgagcg gaggtgagcg acgcgcggac ctgccgctca ggcagttacg gaggttggtg
       61 gcttttggct actcacgcta cgccagggac tgaggagtgc cagctgaggt gagcgcacga
      121 ctcgtggagg ccactggccg gtcgcgtcgc gacgaggctt cccttcctag gactcggggt
      181 gacgctgcgg tgcggagcgg gaagccaccg ccgacgtctg tggcggacga gggcagtgtc
      241 ccacgggcgc ccggttcccc cggggcggct cccagccttc tgcagcaggc agagaggttg
      301 cacagagaat cctcctggct gatggataga cagagatgtt cattactcaa ctcctccaca
      361 aagaagagct gaagatgcac agttgtgttc agaggtgagt gatcaattgg actcctatga
      421 gaatctgaga cctgggacaa cagcagaaga agggaaacag aatcatggtg cctgccagcc
      481 cacagccaca gctgcagagg acaaacatcc ctgtgaggac gacaggccca gcacactgcc
      541 agcgtgtgtg ctggtaactt ttgatcctgg aggttttcat aatttgatgt ctacagctca
      601 ctgacatcaa aaacctagaa tctaggtcac acactcgtct tggtgtagta aagcgacact
      661 cgaggatctg acagtgatgc cactgaaggc tgtaaaatga aaataagctc aagtcaagag
      721 agaggaaaaa accaaagtga agctgtttct tctcctgtgt actcgtcaga ctgccttgaa
      781 atttaactaa aaatatgaca gctctttctt caaagaactg ctctcttcaa taccagctcc
      841 atcagtctcc gcagctcctg gaggcctcct gtctgttgtt cttgatcatc ctggggaaag
      901 tgttattaaa catcctcctt ctaagagtga gaaggggaga cgcccgctgg actttgatgg
      961 agtacttctg cttctcactc gcacttgtcg atctcctgct gttggtaaac atttccatcc
     1021 tgacctactt cagggacttt gtagttctag gtattaggtt taccagatac cacatctgtc
     1081 tgctcacaca aattatttcc ttcacttatg gcttcttgca ttacccagtc tgctcactgg
     1141 cttgtataga ctactggtgt aatctgtcca gagccagcaa gcagtcatct aggtggcaga
     1201 aattacttta tttcttgaca gtcattttaa cttggatctc agtccttgct tacgttttgg
     1261 ttgacccggc catctcagtc agcctaaagg cacacagggg ctatgtgtac cagtgccccg
     1321 cctatgtcag cactcagagt cactggctct cactgtctat gctgatggtt ttatttgtgg
     1381 cttttctgat ttcatggcag gaagttgttg ccttgcttca ggctatgagg atagcatcct
     1441 ataagagcaa ggccgccctc tactttcctt tcccactcca ctgcggttac gccctgagct
     1501 gcagagaagc actcttgccc aggctcatcg tgtgctttct tgggacctgg tttccctttg
     1561 tagcacttca ggtcctcatc ctctccctca gagttcagat cccggcgtac atagaaatga
     1621 acgtcccctg gctgtacttt gtcaacagtt tcctcatcgc tgcagtttat tggtttaact
     1681 gccacaagct tgatttaaga gacagctcgt tacctgtgga tcctttcatc aactggaaat
     1741 gctgctttgt tccagtccat agacttaagc aagtggagag gcccatgtcc atagtcatct
     1801 gttagcatgc tgctgtgctg ggaggaactt cagaagcacc aagatcagtc tcacaaggac
     1861 agaggtggct cgggacagga actgaagctc gagtccccct ttccagcaca gcgtccgtgg
     1921 ggcagatgcc aagtagtgct gaggatacat tagcacagca gaatgtttat gcctgctcga
     1981 caacattgtg gaatatttgg tattaatcca aatgcaaagt aaacacatta acatgtgtcc
     2041 agcttgatgt tttactccaa aaaaactact gggtgcaaaa tgttatataa atttgagatt
     2101 ctatttgcca actttaagat ctgagcttaa gtattttata aactttagag caaaaataaa
     2161 agacttaaca ggatttggta taaataaaat atattgggag attagctc
//
