LOCUS       NM_001004761            7143 bp    mRNA    linear   ROD 29-OCT-2024
DEFINITION  Mus musculus G protein-coupled receptor 158 (Gpr158), mRNA.
ACCESSION   NM_001004761 XM_140850
VERSION     NM_001004761.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7143)
  AUTHORS   Wei,S., Jiang,J., Wang,D., Chang,J., Tian,L., Yang,X., Ma,X.R.,
            Zhao,J.W., Li,Y., Chang,S., Chi,X., Li,H. and Li,N.
  TITLE     GPR158 in pyramidal neurons mediates social novelty behavior via
            modulating synaptic transmission in male mice
  JOURNAL   Cell Rep 43 (10), 114796 (2024)
   PUBMED   39383040
  REMARK    GeneRIF: GPR158 in pyramidal neurons mediates social novelty
            behavior via modulating synaptic transmission in male mice.
REFERENCE   2  (bases 1 to 7143)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 7143)
  AUTHORS   Wei,S., Zheng,L., Chang,J., Jiang,J., Zhou,Z., Liao,H., Song,K.,
            Liu,X., Chi,X., Li,H., Kuang,X. and Li,N.
  TITLE     G protein-coupled receptor 158 modulates sensitivity to the
            sedative-hypnotic effect of ethanol in male mice
  JOURNAL   Alcohol Clin Exp Res (Hoboken) 47 (7), 1261-1270 (2023)
   PUBMED   37128649
REFERENCE   4  (bases 1 to 7143)
  AUTHORS   Laboute,T., Zucca,S., Holcomb,M., Patil,D.N., Garza,C.,
            Wheatley,B.A., Roy,R.N., Forli,S. and Martemyanov,K.A.
  TITLE     Orphan receptor GPR158 serves as a metabotropic glycine receptor:
            mGlyR
  JOURNAL   Science 379 (6639), 1352-1358 (2023)
   PUBMED   36996198
REFERENCE   5  (bases 1 to 7143)
  AUTHORS   Chang,J., Song,Z., Wei,S., Zhou,Y., Ju,J., Yao,P., Jiang,Y.,
            Jin,H., Chi,X. and Li,N.
  TITLE     Expression Mapping and Functional Analysis of Orphan
            G-Protein-Coupled Receptor GPR158 in the Adult Mouse Brain Using a
            GPR158 Transgenic Mouse
  JOURNAL   Biomolecules 13 (3), 479 (2023)
   PUBMED   36979415
  REMARK    GeneRIF: Expression Mapping and Functional Analysis of Orphan
            G-Protein-Coupled Receptor GPR158 in the Adult Mouse Brain Using a
            GPR158 Transgenic Mouse.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 7143)
  AUTHORS   Lodder,E.M., Scicluna,B.P., Beekman,L., Arends,D., Moerland,P.D.,
            Tanck,M.W., Adriaens,M.E. and Bezzina,C.R.
  TITLE     Integrative genomic approach identifies multiple genes involved in
            cardiac collagen deposition
  JOURNAL   Circ Cardiovasc Genet 7 (6), 790-798 (2014)
   PUBMED   25217174
REFERENCE   7  (bases 1 to 7143)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   8  (bases 1 to 7143)
  AUTHORS   Orlandi,C., Posokhova,E., Masuho,I., Ray,T.A., Hasan,N., Gregg,R.G.
            and Martemyanov,K.A.
  TITLE     GPR158/179 regulate G protein signaling by controlling localization
            and activity of the RGS7 complexes
  JOURNAL   J Cell Biol 197 (6), 711-719 (2012)
   PUBMED   22689652
  REMARK    GeneRIF: GPR158/179 recruited RGS complexes to the plasma membrane
            and augmented their ability to regulate GPCR signaling
REFERENCE   9  (bases 1 to 7143)
  AUTHORS   Bjarnadottir,T.K., Fredriksson,R. and Schioth,H.B.
  TITLE     The gene repertoire and the common evolutionary history of
            glutamate, pheromone (V2R), taste(1) and other related G
            protein-coupled receptors
  JOURNAL   Gene 362, 70-84 (2005)
   PUBMED   16229975
REFERENCE   10 (bases 1 to 7143)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Hara,Y., Nagase,T.,
            Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: I. The complete nucleotide sequences of 100 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 9 (5), 179-188 (2002)
   PUBMED   12465718
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK083234.1 and AB093287.1.
            
            On Sep 21, 2004 this sequence version replaced XM_140850.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660815.177088.1,
                                           SRR1660821.137458.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2863              AK083234.1         27-2889
            2864-7143           AB093287.1         1969-6248
FEATURES             Location/Qualifiers
     source          1..7143
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 14.92 cM"
     gene            1..7143
                     /gene="Gpr158"
                     /gene_synonym="5330427M13Rik; mGlyR; mKIAA1136"
                     /note="G protein-coupled receptor 158"
                     /db_xref="GeneID:241263"
                     /db_xref="MGI:MGI:2441697"
     exon            1..1591
                     /gene="Gpr158"
                     /gene_synonym="5330427M13Rik; mGlyR; mKIAA1136"
                     /inference="alignment:Splign:2.1.0"
     CDS             690..4292
                     /gene="Gpr158"
                     /gene_synonym="5330427M13Rik; mGlyR; mKIAA1136"
                     /note="probable G-protein coupled receptor 158;
                     metabotropic glycine receptor"
                     /codon_start=1
                     /product="metabotropic glycine receptor precursor"
                     /protein_id="NP_001004761.1"
                     /db_xref="CCDS:CCDS15722.1"
                     /db_xref="GeneID:241263"
                     /db_xref="MGI:MGI:2441697"
                     /translation="MGAMAYSLLFCLLLAHLGLGEVGASLDPPGRPDSPRERTPRGKQ
                     HGQQLPRASAPDPSIPWSRSTDGTILAQKLAEEVPVDVASYLYTGDFHQLKRANCSGR
                     YELAGLPGKSPSLASSHPSLHGALDTLTHATNFLNMMLQSNKSREQTVQDDLQWYQAL
                     VRSLLEGEPSISRAAITFSTESLSTPAPQVFLQATREESRILLQDLSSSAHHLANATL
                     ETEWFHGLRRKWRPHLHRRGSNQGPRGLGHSWRRRDGLGGDRSHVKWSPPYLECENGS
                     YKPGWLVTLSAAFYGLQPNLVPEFRGVMKVDISLQKVDIDQCSSDGWFSGTHKCHLNN
                     SECMPIKGLGFVLGAYQCICKAGFYHPRVFSVNNFQRRGPDHHFSGSTKDVSEETHVC
                     LPCREGCPFCADDRPCFVQEDKYLRLAIISFQALCMLLDFVSMLVVYHFRKAKSIRAS
                     GLILLETILFGSLLLYFPVVILYFEPSTFRCILLRWARLLGFATVYGTVTLKLHRVLK
                     VFLSRTAQRIPYMTGGRVMRMLAVIVLVVFWFLVGWTSSMCQNLERDILLVGQGQTSD
                     HLTFNMCLIDRWDYMTAVAEFLFLLWGIYLCYAVRTVPSAFHEPRYMAVAVHNELIIT
                     AIFHTIRFVLASRLQPDWMLMLYFAHAHLTVTVTIGLLLIPKFSHSSNNPRDDIATEA
                     YEDELDMGRSGSYLNSSINSAWSEHSLDPEDIRDELKKLYAQLEIYKRKKMITNNPHL
                     QKKRCSKKGLGRSIMRRITEIPETVSRQCSKEDKEGTDHSAAKGTGLVRKNPTESSGN
                     TGRPKEESLKNRVFSLKKSHSTYDHVRDQTVESSSLPMESQEEEATENSTLESLSSKK
                     LTQKLKEDSEAESTESVPLVCKSASAHNLSSEKKPGHPRTSMLQKSLSVIASAKEKTL
                     GLAGKTQTLVMEDRAKSQKPKDRETIRKYSNSDNVETIPNSGHMEEPRKPQKSGIMKQ
                     QRVSLPTANPDVSSGITQIKDNFDIGEVCPWEVYDLTPGPMPSEPKAQKHVSIAASEV
                     EQNPASFLKEKSYHKSKATEGLYQANHKSIDKTEVCPWEIHSQSLLEDENRLISKTPV
                     LPGRAREENGSQLYTTNMCAGQYEELPHKVVAPKVENENLNQMGDQEKQTSSSVDIIP
                     GSCNSSNNSHQPLTSRAEVCPWEFEPLEQPNAERSVTLPASSALSANKIPGPQK"
     exon            1592..1697
                     /gene="Gpr158"
                     /gene_synonym="5330427M13Rik; mGlyR; mKIAA1136"
                     /inference="alignment:Splign:2.1.0"
     exon            1698..1800
                     /gene="Gpr158"
                     /gene_synonym="5330427M13Rik; mGlyR; mKIAA1136"
                     /inference="alignment:Splign:2.1.0"
     exon            1801..2024
                     /gene="Gpr158"
                     /gene_synonym="5330427M13Rik; mGlyR; mKIAA1136"
                     /inference="alignment:Splign:2.1.0"
     exon            2025..2093
                     /gene="Gpr158"
                     /gene_synonym="5330427M13Rik; mGlyR; mKIAA1136"
                     /inference="alignment:Splign:2.1.0"
     exon            2094..2203
                     /gene="Gpr158"
                     /gene_synonym="5330427M13Rik; mGlyR; mKIAA1136"
                     /inference="alignment:Splign:2.1.0"
     exon            2204..2442
                     /gene="Gpr158"
                     /gene_synonym="5330427M13Rik; mGlyR; mKIAA1136"
                     /inference="alignment:Splign:2.1.0"
     exon            2443..2581
                     /gene="Gpr158"
                     /gene_synonym="5330427M13Rik; mGlyR; mKIAA1136"
                     /inference="alignment:Splign:2.1.0"
     exon            2582..2687
                     /gene="Gpr158"
                     /gene_synonym="5330427M13Rik; mGlyR; mKIAA1136"
                     /inference="alignment:Splign:2.1.0"
     exon            2688..2834
                     /gene="Gpr158"
                     /gene_synonym="5330427M13Rik; mGlyR; mKIAA1136"
                     /inference="alignment:Splign:2.1.0"
     exon            2835..7143
                     /gene="Gpr158"
                     /gene_synonym="5330427M13Rik; mGlyR; mKIAA1136"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7123..7128
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gpr158"
                     /gene_synonym="5330427M13Rik; mGlyR; mKIAA1136"
                     /note="hexamer: AATAAA"
     polyA_site      7143
                     /gene="Gpr158"
                     /gene_synonym="5330427M13Rik; mGlyR; mKIAA1136"
                     /note="major polyA site"
ORIGIN      
        1 gcggccaagc tgtctcttta aactgctttc atctgagagc agagaaaggc agcgctgtgg
       61 tttgtggcca aacctaaagg ctctagttaa tcagctgcct ggctgtctgg actgcagaca
      121 cacgaacgtc ttcaaagaaa accttggttc cttgggactc gccgctgagc tcgcggcttg
      181 gatctgtgtg cgcgcttcca tctccgggcg aagcggtcga ggaggggcca gaactgggag
      241 gcgggaacga cctgccaagg gtgagatgat ggagcagcat ctttggtggc cgcggtggca
      301 acatcagctg catcagcagc atcagcatca gctcttgaac acacctcaat gagagcggcg
      361 gtggaagcgg ctgagcagaa agacgtaagc gggctaacta tagctgctgg ggatgtaacc
      421 tgtttggctc aaggctgcga ggtgcgtaat cccgagccga cccattgtgg agccgggcgc
      481 agccagcatt gccacaggtg atttggtctg tgacggcagc tgagccagct gggccaattt
      541 caaaacattc ttattttaaa gtccatctgg actgggcgcc acctggagaa gaaggaagcc
      601 tcccctcaaa agtcttactg atgataaatt gaggaccaaa atttacaaag tgactcctcc
      661 ggttatcgcc tctcttctat gctagacaga tgggagccat ggcttactct ttactcttct
      721 gcctcctgct cgctcatctg ggattgggag aggttggtgc cagcctcgac cctccgggac
      781 ggccagattc ccctcgagag aggactccga gggggaagca gcatggtcag cagctgccgc
      841 gagcctctgc cccagacccc tctattccct ggagccgctc cactgacggc accatcttgg
      901 cacaaaaact agccgaggag gtgcccgtgg acgtggcctc ttacctctac actggggact
      961 tccaccagct gaagagagcc aactgctcag gccgctacga gttggctggc ctgccgggaa
     1021 agtcaccgtc cctagccagc tcccatcctt ccttgcacgg ggcgctggac actctgacac
     1081 acgccaccaa cttcctcaac atgatgttgc agagcaataa gtctcgggaa cagaccgtgc
     1141 aggatgacct gcagtggtac caggctctgg tgcgaagtct cctggagggt gagcccagca
     1201 tctcccgggc ggccatcacc ttcagcaccg agtcgctgtc cacgcccgcc ccgcaggtct
     1261 tcctccaggc cacccgcgag gagagtcgca tcctgctgca ggacctgtcc tcctccgctc
     1321 accacctggc taacgccact ctagagaccg agtggttcca tgggcttcgg cgaaagtgga
     1381 ggccccactt gcaccgccgt ggctccaatc aggggccacg gggcctaggc cacagctggc
     1441 ggcgcaggga tgggcttgga ggggacagga gccacgtcaa gtggtcccca ccttatctgg
     1501 agtgcgagaa tgggagttac aagcctgggt ggctggtcac gctctctgct gccttctacg
     1561 ggcttcaacc taacctggtc ccggaattca ggggtgtgat gaaagttgat ataagccttc
     1621 agaaagtgga cattgaccaa tgttcgagtg atggctggtt ttcaggaact cacaaatgcc
     1681 accttaacaa ctcagagtgt atgccaatca aaggcctggg attcgtgctt ggagcctatc
     1741 agtgcatttg caaagcaggg ttctatcatc cccgtgtctt ctcagtgaac aacttccaga
     1801 gaaggggtcc agatcaccat ttttcaggaa gcacaaagga tgtgtcagaa gaaacccacg
     1861 tctgcctgcc ctgcagagaa ggctgcccct tctgtgctga tgatcgtcca tgctttgtcc
     1921 aggaggataa atacctgcgg ctcgctatta tctctttcca agccctgtgt atgctgctgg
     1981 actttgtcag catgctggtg gtctaccatt ttcgcaaagc aaagagcatc agggcatctg
     2041 ggctcatcct gttggaaaca atattgtttg gttctctgct cctatacttt ccggtcgtta
     2101 ttctgtactt tgagccaagt acatttcgtt gtattctcct aaggtgggct cgtcttcttg
     2161 gttttgctac tgtttatgga actgtgaccc tcaagcttca cagggttttg aaggtgttcc
     2221 tttcacgaac agcacaaaga atcccataca tgactggtgg tcgggtcatg aggatgctgg
     2281 cagtaatagt cttggttgtg ttttggtttc ttgttggctg gacttcttct atgtgccaga
     2341 atttggagcg ggatattttg cttgttggcc aagggcaaac atctgatcac ctcaccttca
     2401 atatgtgcct cattgaccgc tgggattaca tgacagcagt tgctgaattt ttattcctct
     2461 tgtggggcat ttatctctgc tatgcagtgc ggactgtccc ttcagcattt catgagccac
     2521 gctacatggc tgtcgcagtt cacaatgagc tcattatcac ggctatattc catacaatta
     2581 gattcgtgct cgcctcgaga cttcagcccg actggatgct gatgctgtac tttgcacatg
     2641 ctcacttgac tgtgacagtc accattgggc tgcttctaat tccaaagttt tcacattcaa
     2701 gcaataatcc ccgagatgac attgctacgg aagcatatga agatgagctg gacatgggtc
     2761 gctctggatc ctacctgaac agcagtatca attcagcctg gagtgaacac agcctagatc
     2821 cagaagacat tcgggatgaa ctgaaaaaac tctatgctca gttagaaata tacaaacgta
     2881 aaaagatgat cacaaacaac ccccaccttc agaaaaaacg gtgctccaag aagggcttag
     2941 gccggtccat catgaggcgc atcactgaga tcccagagac agtcagcaga cagtgctcca
     3001 aagaggacaa ggaaggcaca gaccacagtg cagccaaggg gacaggcctt gtccggaaga
     3061 accctactga gtcctcaggg aatacaggga gacccaagga agagtccctt aaaaatcggg
     3121 tcttctctct caagaaatcc cacagcacat atgaccatgt gagagaccaa actgtagaat
     3181 ccagcagctt gcccatggag agccaggagg aggaggccac cgaaaattca accttggagt
     3241 cgctgtcaag taaaaaactg acacaaaagc tcaaagaaga tagtgaggcc gagtccactg
     3301 agtcagtgcc gttggtctgc aagtcagcca gtgctcacaa cctcagctca gagaagaagc
     3361 ctgggcaccc acgtacatct atgttacaga aatctctcag tgtcattgca agtgccaagg
     3421 agaagacact tggcctggct ggcaaaaccc agactttagt tatggaagac cgagctaagt
     3481 cccagaaacc aaaagataga gagaccatca ggaagtactc aaattcagat aatgtagaga
     3541 ctatcccaaa ctccggtcac atggaggagc caagaaagcc ccagaaatct gggattatga
     3601 aacagcagag ggtcagcctc cccactgcca atcctgacgt gagctccggt atcacccaga
     3661 taaaggacaa ttttgatatc ggagaagtat gcccttggga ggtttatgac ctgacccctg
     3721 gtcctatgcc ttcagagcca aaagctcaaa aacacgtatc aatcgcagct tctgaagtgg
     3781 aacaaaaccc tgcttcgttt ttgaaggaga agtcctacca caagtctaag gcaactgaag
     3841 gtctctacca agccaatcac aagagcatag acaagacaga ggtgtgcccc tgggaaatcc
     3901 acagtcagtc ccttttagaa gatgagaatc gtctgatttc taagactcca gttctcccag
     3961 ggagagccag agaggagaat ggaagccagc tctacacaac caatatgtgt gctgggcaat
     4021 atgaagaact gccccacaaa gtcgtagcac caaaagtaga gaatgaaaat ctcaaccaaa
     4081 tgggagacca ggagaaacag acatcttcct ctgtggatat cattcctggc tcctgtaact
     4141 caagtaataa ctcccatcag cccttaacat cacgagccga agtgtgtccc tgggagttcg
     4201 agcccctaga acaaccaaat gctgaaagaa gcgtaacttt acctgcctcc tctgctttaa
     4261 gtgcaaataa gataccaggg cctcagaaat aggaagtctg ggacactttc aaagtggacc
     4321 accctgggaa gaaaggggta atcccgagtt tgataaaaat agatctgaaa atcacaagtt
     4381 accaaggcat ctttgttagc ctagggaaac atggcacata gtgcagtaag gtgaaggcaa
     4441 gggctggaga aggccagaaa aaggcaatta tgcatcataa gaaggaaggc tgactctgcc
     4501 atgaaaagcc agatcaacac tggaggacag cttagcattt ccgcctgttt aagggacatt
     4561 gccctgtctg tctttacaca tgggattgaa tggtaccaag caagattcac caggaggcat
     4621 ggaagacaga cgcatggatt ttaagatggg aaaacttaga taaatgtgac tgtgattcta
     4681 agtagctgac tgaaaagcca accttcatta cctatttaac cttggtagca ctgctaactt
     4741 aatgcaccct gatacctttt atatacacga ttgctctcat tttcttaaaa tctgttccag
     4801 tacattgttg tgtcttgtat tcaagcattc cagattgtat aatttttgca aataactttg
     4861 atattatatg acacaacaca tttatgcaat ctgcagctac tcaattgtca ttgcaaccta
     4921 ccaaatacct gctatcatct accaagtgtg gttgagtctt ggagtacagt aagctttctc
     4981 tggcttagga agccataaca gttaagatga aaacttttag tttgggctgt ggtttatata
     5041 gtgaagttgg gtctgactct tttgtttccc accatggctt gttgtaatgt cttaattttt
     5101 aaatataagt tgagttgctt attctacact tcttgtaggg actctgaagc tttattaatc
     5161 tcggagatga agtggtcctg tttagtcata tgtctcagta agttaaggac aacttatcca
     5221 ttgtttgttc caagtcagag ctaaatcaac ccaatgactc tttcagtatt tcacattagc
     5281 atttcctaag gaagaagccg aatgaggaaa ctatgctgta cattgttacc aacagaagag
     5341 gccaactcta ggagcgcctt aacaacgagt gcatactgca ggtccaggaa attgcctttc
     5401 atgacaaata cagaaaggtc gctcctaata gctccaggga ttatttttat aaagagaaaa
     5461 attaatgata gcatcaagat cattgtatgg atatattttt attatgcata ctgaaaatat
     5521 attttaaatt accttaaact atttattctc ataaactttt attcattgct tcatctaggt
     5581 acagaatttg ctgggctcaa atcccaaaga gattttataa cttgatttac tcaaagccca
     5641 taggtggtac aggctcttta cactccccag taccagaact tacaagtcct tcaaactgtc
     5701 cttgcaagcc acctagctca aaatgcaaag cctaagattg gtgtgcatac atcaaagcat
     5761 atcttctaga acttgctgca ttccatgctg atctctagca taaacatcct gagcttctga
     5821 cttagctcta aggattgcaa tgccgaaata agactctaaa atccaggcac atttcattta
     5881 aagatctatc acttaaaact acagcccagg cttgattttc tcccatcata aatactaaac
     5941 aactgcttat gtgacgaaga catttccatc cataggaact gttttacctt tggtgagcaa
     6001 caaaaagaat ttgctaggat gatgcaggag gggagaagga atcagaaggt ggatataagg
     6061 ctgtgcttat gctttgtgtc tatcatcaaa ctttgctcag tgtttacttt tgtattcagg
     6121 agaaagcaag cacttgagga gttggcagag ctgggcatac ccatttgctt gcttcattca
     6181 ttactcaggt tggtgggcta ggtttggaaa tctatagaga ttttattgct aactgctgcc
     6241 ttcattaatc cctatcatcc ccacccttcc aatcaaagcc tatctacttt gtgactttag
     6301 aattctattt tgaggagcat ttgtgaactt ggcttagagt ttgtagactt gcgtacttgt
     6361 ttcacttgtg tctgagagct gttagcacta gatttgcctc agaattaagc aggcaactgt
     6421 cactgacttc actgcacttc agggtgaccc tgcttgatgt gtggctcaca gaagatttgc
     6481 caaattatac catagtgaca gtctgcccct gccccccata gattactctc caccgccaca
     6541 aatcagcaca aatagctagg ttctttccta gagcttcatt ttcataactt atcaccaaaa
     6601 gaaattgaac tctgtcattc tggaagctct tttccctggc tgagaacaat agaaagtgca
     6661 tacagtgtga aggtctcaca aacatttgct aggttgtcct ttcaatgcat gtgcaggctg
     6721 caccctgttg ttgttttaag ccagggttta taaataagta gatttatatc tgtcttaata
     6781 gaagtgtata ttttatgcaa gaattaaatg ctttacaaca taaattatga cttgacctct
     6841 cgtaaacttc ggtggcaata cggattgaat cccgacagtt gtcttgtatt tgcttcctag
     6901 gtttctgcat gcgagtggtg ataggtagga ctgacaacac actgcctttg acttctagca
     6961 cttagcagtc aagagttgta gagtcaacaa agctgtaagt ctcttcactt aacctgtggt
     7021 tcttctaaaa ctattatcta aatctacagc atcccaccat ggaatacctg gtaatttatg
     7081 ttgtgatgtg ttgcagcatg taaataacta taacttctct gcaataaaac atttatatga
     7141 aaa
//
