LOCUS       NM_181543               1772 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus G protein-coupled receptor 151 (Gpr151), mRNA.
ACCESSION   NM_181543
VERSION     NM_181543.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1772)
  AUTHORS   Bielczyk-Maczynska,E., Zhao,M., Zushin,P.H., Schnurr,T.M.,
            Kim,H.J., Li,J., Nallagatla,P., Sangwung,P., Park,C.Y., Cornn,C.,
            Stahl,A., Svensson,K.J. and Knowles,J.W.
  TITLE     G protein-coupled receptor 151 regulates glucose metabolism and
            hepatic gluconeogenesis
  JOURNAL   Nat Commun 13 (1), 7408 (2022)
   PUBMED   36456565
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1772)
  AUTHORS   Allain,F., Carter,M., Dumas,S., Darcq,E. and Kieffer,B.L.
  TITLE     The mu opioid receptor and the orphan receptor GPR151 contribute to
            social reward in the habenula
  JOURNAL   Sci Rep 12 (1), 20234 (2022)
   PUBMED   36424418
  REMARK    GeneRIF: The mu opioid receptor and the orphan receptor GPR151
            contribute to social reward in the habenula.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1772)
  AUTHORS   Gurtan,A., Dominy,J., Khalid,S., Vong,L., Caplan,S., Currie,T.,
            Richards,S., Lamarche,L., Denning,D., Shpektor,D., Gurinovich,A.,
            Rasheed,A., Hameed,S., Saeed,S., Saleem,I., Jalal,A., Abbas,S.,
            Sultana,R., Rasheed,S.Z., Memon,F.U., Shah,N., Ishaq,M.,
            Khera,A.V., Danesh,J., Frossard,P. and Saleheen,D.
  TITLE     Analyzing human knockouts to validate GPR151 as a therapeutic
            target for reduction of body mass index
  JOURNAL   PLoS Genet 18 (4), e1010093 (2022)
   PUBMED   35381001
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1772)
  AUTHORS   Jiang,B.C., Zhang,J., Wu,B., Jiang,M., Cao,H., Wu,H. and Gao,Y.J.
  TITLE     G protein-coupled receptor GPR151 is involved in trigeminal
            neuropathic pain through the induction of Gbetagamma/extracellular
            signal-regulated kinase-mediated neuroinflammation in the
            trigeminal ganglion
  JOURNAL   Pain 162 (5), 1434-1448 (2021)
   PUBMED   33239523
  REMARK    GeneRIF: G protein-coupled receptor GPR151 is involved in
            trigeminal neuropathic pain through the induction of
            Gbetagamma/extracellular signal-regulated kinase-mediated
            neuroinflammation in the trigeminal ganglion.
REFERENCE   5  (bases 1 to 1772)
  AUTHORS   Antolin-Fontes,B., Li,K., Ables,J.L., Riad,M.H., Gorlich,A.,
            Williams,M., Wang,C., Lipford,S.M., Dao,M., Liu,J., Molina,H.,
            Heintz,N., Kenny,P.J. and Ibanez-Tallon,I.
  TITLE     The habenular G-protein-coupled receptor 151 regulates synaptic
            plasticity and nicotine intake
  JOURNAL   Proc Natl Acad Sci U S A 117 (10), 5502-5509 (2020)
   PUBMED   32098843
  REMARK    GeneRIF: These data identify GPR151 as a critical modulator of
            habenular function that controls nicotine addiction vulnerability
REFERENCE   6  (bases 1 to 1772)
  AUTHORS   Quina,L.A., Wang,S., Ng,L. and Turner,E.E.
  TITLE     Brn3a and Nurr1 mediate a gene regulatory pathway for habenula
            development
  JOURNAL   J Neurosci 29 (45), 14309-14322 (2009)
   PUBMED   19906978
REFERENCE   7  (bases 1 to 1772)
  AUTHORS   Lein,E.S., Hawrylycz,M.J., Ao,N., Ayres,M., Bensinger,A.,
            Bernard,A., Boe,A.F., Boguski,M.S., Brockway,K.S., Byrnes,E.J.,
            Chen,L., Chen,L., Chen,T.M., Chin,M.C., Chong,J., Crook,B.E.,
            Czaplinska,A., Dang,C.N., Datta,S., Dee,N.R., Desaki,A.L.,
            Desta,T., Diep,E., Dolbeare,T.A., Donelan,M.J., Dong,H.W.,
            Dougherty,J.G., Duncan,B.J., Ebbert,A.J., Eichele,G., Estin,L.K.,
            Faber,C., Facer,B.A., Fields,R., Fischer,S.R., Fliss,T.P.,
            Frensley,C., Gates,S.N., Glattfelder,K.J., Halverson,K.R.,
            Hart,M.R., Hohmann,J.G., Howell,M.P., Jeung,D.P., Johnson,R.A.,
            Karr,P.T., Kawal,R., Kidney,J.M., Knapik,R.H., Kuan,C.L.,
            Lake,J.H., Laramee,A.R., Larsen,K.D., Lau,C., Lemon,T.A.,
            Liang,A.J., Liu,Y., Luong,L.T., Michaels,J., Morgan,J.J.,
            Morgan,R.J., Mortrud,M.T., Mosqueda,N.F., Ng,L.L., Ng,R.,
            Orta,G.J., Overly,C.C., Pak,T.H., Parry,S.E., Pathak,S.D.,
            Pearson,O.C., Puchalski,R.B., Riley,Z.L., Rockett,H.R.,
            Rowland,S.A., Royall,J.J., Ruiz,M.J., Sarno,N.R., Schaffnit,K.,
            Shapovalova,N.V., Sivisay,T., Slaughterbeck,C.R., Smith,S.C.,
            Smith,K.A., Smith,B.I., Sodt,A.J., Stewart,N.N., Stumpf,K.R.,
            Sunkin,S.M., Sutram,M., Tam,A., Teemer,C.D., Thaller,C.,
            Thompson,C.L., Varnam,L.R., Visel,A., Whitlock,R.M.,
            Wohnoutka,P.E., Wolkey,C.K., Wong,V.Y., Wood,M., Yaylaoglu,M.B.,
            Young,R.C., Youngstrom,B.L., Yuan,X.F., Zhang,B., Zwingman,T.A. and
            Jones,A.R.
  TITLE     Genome-wide atlas of gene expression in the adult mouse brain
  JOURNAL   Nature 445 (7124), 168-176 (2007)
   PUBMED   17151600
REFERENCE   8  (bases 1 to 1772)
  AUTHORS   Ignatov,A., Hermans-Borgmeyer,I. and Schaller,H.C.
  TITLE     Cloning and characterization of a novel G-protein-coupled receptor
            with homology to galanin receptors
  JOURNAL   Neuropharmacology 46 (8), 1114-1120 (2004)
   PUBMED   15111018
  REMARK    GeneRIF: Galanin-receptor like (GalRL) expression is found in the
            dorsal thalamus; hybridization signals are detected in the
            striatum, the locus coeruleus, and several hindbrain nuclei.
REFERENCE   9  (bases 1 to 1772)
  AUTHORS   Berthold,M., Collin,M., Sejlitz,T., Meister,B. and Lind,P.
  TITLE     Cloning of a novel orphan G protein-coupled receptor (GPCR-2037):
            in situ hybridization reveals high mRNA expression in rat brain
            restricted to neurons of the habenular complex
  JOURNAL   Brain Res Mol Brain Res 120 (1), 22-29 (2003)
   PUBMED   14667573
REFERENCE   10 (bases 1 to 1772)
  AUTHORS   Vassilatis,D.K., Hohmann,J.G., Zeng,H., Li,F., Ranchalis,J.E.,
            Mortrud,M.T., Brown,A., Rodriguez,S.S., Weller,J.R., Wright,A.C.,
            Bergmann,J.E. and Gaitanaris,G.A.
  TITLE     The G protein-coupled receptor repertoires of human and mouse
  JOURNAL   Proc Natl Acad Sci U S A 100 (8), 4903-4908 (2003)
   PUBMED   12679517
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC121603.4.
            
            On Jan 22, 2019 this sequence version replaced NM_181543.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AJ564167.1, BC120520.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1772              AC121603.4         42596-44367
FEATURES             Location/Qualifiers
     source          1..1772
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 22.71 cM"
     gene            1..1772
                     /gene="Gpr151"
                     /gene_synonym="C130082O03Rik; GalRL; nGPCR-2037; PGR7"
                     /note="G protein-coupled receptor 151"
                     /db_xref="GeneID:240239"
                     /db_xref="MGI:MGI:2441887"
     exon            1..1772
                     /gene="Gpr151"
                     /gene_synonym="C130082O03Rik; GalRL; nGPCR-2037; PGR7"
                     /inference="alignment:Splign:2.1.0"
     CDS             42..1310
                     /gene="Gpr151"
                     /gene_synonym="C130082O03Rik; GalRL; nGPCR-2037; PGR7"
                     /note="putative G protein-coupled receptor nGPCR-2037;
                     probable G-protein coupled receptor 151 protein;
                     GPCR-2037; G-protein coupled receptor PGR7"
                     /codon_start=1
                     /product="G-protein coupled receptor 151 protein"
                     /protein_id="NP_853521.1"
                     /db_xref="CCDS:CCDS29215.1"
                     /db_xref="GeneID:240239"
                     /db_xref="MGI:MGI:2441887"
                     /translation="MGKAMLRAGFADTNSSNMNESFARLHFAGGYLPSDSKDWRTIIP
                     SLLMAVCLVGLVGNLCVIGILLHGVWKRKPSTIHSLILNLSLADFSLLLFSAPVRAAA
                     YSKGVWDLGWFICKSSDWFTHVCMAAKSLTFVVVAKACFAYASDPAKQESIHSRTIWS
                     VLAGIWVVASLLPLPEWLFSTTRRHAGVEMCLVDVPAVAEEFMSMFGKLYPLLVFCLP
                     LLLAGVYFWRAYDQCKTRCTKTRNLRDQMRSKQLTVMLLSTAIISALLWLPEWIAWLW
                     VWHVKAGGPMPPQGFIALSQVLMFFTSTANPLIFLVMSEEFKAGLKGLWKWMITRKPA
                     VTSEVQEAPAGNTEALPGKAPSPETQTCILDTDGRGSPDDSKEKSGKVVAPILPDVEQ
                     FWHERDAVPSAQDNDPIPWEHEGQETEGCN"
ORIGIN      
        1 ccaacctaaa caagaagcta ccatctgcag ggaggagctt gatgggaaag gcaatgctga
       61 gagctgggtt tgccgacacc aattccagca acatgaacga gtcgtttgct cgcctccact
      121 ttgcaggagg ctacctgccg tctgactcca aggactggag gaccatcatt ccgtctctct
      181 tgatggccgt gtgcctggtg ggtctcgtgg gaaacctgtg tgtgattggc attctccttc
      241 atggcgtttg gaaaagaaag ccatccacga tccactccct gattctgaat ctaagcctgg
      301 ctgacttctc tctcctgctc ttctctgcac ctgtccgagc ggcagcatac tccaagggcg
      361 tttgggatct cggctggttc atctgcaagt cctctgactg gttcacccac gtgtgcatgg
      421 cagccaagag cttgacattt gttgtggtag ccaaagcatg cttcgcgtat gcaagtgacc
      481 cagccaagca agagagtatc cacagccgca ccatctggtc agtgctggcg ggcatctggg
      541 ttgtagccag cctgcttccc ctgccagaat ggctctttag caccaccaga cgtcacgcag
      601 gtgtggaaat gtgcctcgtg gatgtgccag ctgtggcaga agaattcatg tccatgttcg
      661 gtaagctcta ccctctgctg gtgttctgcc ttcctttact tctggctggc gtttatttct
      721 ggcgagctta tgaccaatgt aagacacgat gtacgaaaac tcgaaatctg agagaccaga
      781 tgcgttcaaa gcaactcaca gtgatgctgc taagcactgc aatcatctct gctcttctgt
      841 ggctcccaga gtggatagcc tggctgtggg tatggcatgt gaaggctgga gggccgatgc
      901 caccacaggg gttcatagcc ctgtctcaag ttctcatgtt tttcacctcc acagcaaacc
      961 ctctcatttt tctagttatg tctgaagagt tcaaggcagg cttgaaaggc ctatggaaat
     1021 ggatgataac cagaaagcca gcagttactt cagaggttca ggaggcacct gctggaaaca
     1081 cagaggccct tcccggaaag gctccatcac cagagaccca aacatgcatc ctagacacag
     1141 acggacgtgg gtctcctgat gacagcaaag agaaatctgg taaggtggtg gctcccatcc
     1201 tccctgacgt ggagcagttt tggcacgaga gggatgctgt cccttcagca caagacaatg
     1261 accctatacc ctgggaacac gaaggccaag agacagaggg ctgcaattaa cagacttgag
     1321 tttcaaagaa aagcaaattg tcgttactgt gtttacttgt accactgctt agcaatattg
     1381 atgaagtaaa ttgccattag aaattgcaaa gatttctgct ttcaaactat agaacctggt
     1441 aagtagaaag gcatgtagca attaggcttc agaactaaag tccgtctaaa gaaatcaatt
     1501 gaagtgctat gtaaagaaaa ctttcagtga ttatagggct cacgctggct ttcccccagg
     1561 gtatccctta aatctagccc tgttctgcag tggctggagt agtttatcag actgagccaa
     1621 tgtactctgt ttcttcctga agctgctacc ctcaatgtac cagcaagtta tatttcacct
     1681 aagcatagct caaaatctct atctcctttg gctttttaaa actataaatt tcacttgtaa
     1741 attctcttca cttgcttaat aaatgttaat tg
//
