LOCUS       NM_181754               3433 bp    mRNA    linear   ROD 07-MAY-2024
DEFINITION  Mus musculus G protein-coupled receptor 141 (Gpr141), mRNA.
ACCESSION   NM_181754
VERSION     NM_181754.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3433)
  AUTHORS   Sawabe,A., Okazaki,S., Nakamura,A., Goitsuka,R. and Kaifu,T.
  TITLE     The orphan G protein-coupled receptor 141 expressed in myeloid
            cells functions as an inflammation suppressor
  JOURNAL   J Leukoc Biol 115 (5), 935-945 (2024)
   PUBMED   38226682
  REMARK    GeneRIF: The orphan G protein-coupled receptor 141 expressed in
            myeloid cells functions as an inflammation suppressor.
REFERENCE   2  (bases 1 to 3433)
  AUTHORS   Fredriksson,R., Hoglund,P.J., Gloriam,D.E., Lagerstrom,M.C. and
            Schioth,H.B.
  TITLE     Seven evolutionarily conserved human rhodopsin G protein-coupled
            receptors lacking close relatives
  JOURNAL   FEBS Lett 554 (3), 381-388 (2003)
   PUBMED   14623098
REFERENCE   3  (bases 1 to 3433)
  AUTHORS   Vassilatis,D.K., Hohmann,J.G., Zeng,H., Li,F., Ranchalis,J.E.,
            Mortrud,M.T., Brown,A., Rodriguez,S.S., Weller,J.R., Wright,A.C.,
            Bergmann,J.E. and Gaitanaris,G.A.
  TITLE     The G protein-coupled receptor repertoires of human and mouse
  JOURNAL   Proc Natl Acad Sci U S A 100 (8), 4903-4908 (2003)
   PUBMED   12679517
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122886.3 and AC153016.2.
            
            On Dec 29, 2009 this sequence version replaced NM_181754.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK154688.1, BY748361.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164135 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-128               AC122886.3         81105-81232         c
            129-196             AC122886.3         61965-62032         c
            197-303             AC122886.3         36430-36536         c
            304-497             AC153016.2         214954-215147       c
            498-3433            AC153016.2         209626-212561       c
FEATURES             Location/Qualifiers
     source          1..3433
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 7.04 cM"
     gene            1..3433
                     /gene="Gpr141"
                     /gene_synonym="PGR13"
                     /note="G protein-coupled receptor 141"
                     /db_xref="GeneID:353346"
                     /db_xref="MGI:MGI:2672983"
     exon            1..128
                     /gene="Gpr141"
                     /gene_synonym="PGR13"
                     /inference="alignment:Splign:2.1.0"
     exon            129..196
                     /gene="Gpr141"
                     /gene_synonym="PGR13"
                     /inference="alignment:Splign:2.1.0"
     exon            197..303
                     /gene="Gpr141"
                     /gene_synonym="PGR13"
                     /inference="alignment:Splign:2.1.0"
     exon            304..497
                     /gene="Gpr141"
                     /gene_synonym="PGR13"
                     /inference="alignment:Splign:2.1.0"
     exon            498..3433
                     /gene="Gpr141"
                     /gene_synonym="PGR13"
                     /inference="alignment:Splign:2.1.0"
     CDS             512..1429
                     /gene="Gpr141"
                     /gene_synonym="PGR13"
                     /note="G-protein coupled receptor PGR13"
                     /codon_start=1
                     /product="probable G-protein coupled receptor 141"
                     /protein_id="NP_861419.3"
                     /db_xref="CCDS:CCDS26264.1"
                     /db_xref="GeneID:353346"
                     /db_xref="MGI:MGI:2672983"
                     /translation="MDGYNTSENSSCDPILAHHLTSIYFIVLIGGLVGLISILFLLVK
                     MNSRSVTTMAVINLVVVHGVFLLTVPFRLAYLIKGTWTFGLPFCKFVSAMLHIHMYLT
                     FLFYVVILVIRYLIFFKRRDKVEFYRKLHAVAASSAMWLLVIVIVVPLVVSQYGNSEE
                     YNEQQCFRFHKELGHDSVRVINYMIVIVVIAVALILLGFQVFITLSMVRKFRHSLLSH
                     QEFWAQLKNLFFIGIIIICFLPYQFFRIYYLYVVAHSKSCKNKVAFYNEILLSTTAIS
                     CCDLLLFVFGGSHWVKQKIVDMWNCLLCH"
ORIGIN      
        1 ggtcagttta cagactttgt gaacaaggag ggtggatgtg ccaagacagc cctgctgctg
       61 gagagcctct ctggaattta gaccggtaac ccgactcagc aactcatact ggaaatctgg
      121 cttttaaggt ggtaatgact gactctcgac tatgagtctg agcatggaca aaggaatatg
      181 agacactgat ttctataatt gggagaggga ctcacaactt ggaaccccag atagctgtaa
      241 tcagagcaaa catgctcagt attggtgaga aagaagaacc ccagaagcac ctgaagatgg
      301 aacgaatcag tcttactacg ctaacggtgt aaggaagtgg tgagcagaag tgttggtggc
      361 attttcgtgc ttgactcaaa ggaaaacagg actgctttta ctcaggagaa ctgctctttt
      421 acagagaaaa aggaaaggtg aatagaggga ctacccagta gaacccagcc aacttcagag
      481 cttccaggga gatactggta atgtttgaag aatggatgga tataatacct ctgagaattc
      541 ctcttgtgac cctatactgg cacaccactt aacatcgatt tacttcatag tgctcattgg
      601 aggactggta ggcctcatct ccatcctgtt cttgctggtg aaaatgaact cacgttcagt
      661 gaccaccatg gctgtcatca acctcgtggt ggttcatggg gtcttcctac tgacggtgcc
      721 tttccgcttg gcatacctca tcaaagggac ttggacgttt ggattaccct tctgcaaatt
      781 tgtgagtgcc atgttacata tccacatgta cctcacgttc ctcttctacg tggtgatact
      841 agtcatcaga tacctcatct tcttcaagcg tagagacaaa gtagaattct atagaaaatt
      901 gcatgcagtt gctgcaagtt ctgccatgtg gcttctggtg attgttattg ttgtgccctt
      961 ggtggtttct cagtatggaa atagcgaaga atacaatgag caacagtgct ttagattcca
     1021 taaagaactt ggccatgatt ctgtgcgagt tatcaactat atgatagtca ttgttgtcat
     1081 agctgttgcg ttgattctct tgggtttcca ggtcttcatc acattgtcca tggtgcggaa
     1141 gtttcgccac tccttactat cccaccagga gttctgggca caactgaaaa atcttttctt
     1201 tataggtatc attattattt gttttcttcc ctaccagttc ttcaggattt attacttgta
     1261 tgttgtggca cattccaaga gctgtaaaaa caaagttgca ttttacaatg aaatcctatt
     1321 gagcacaaca gccatcagct gctgtgattt gctgcttttt gtctttggag gaagccattg
     1381 ggttaagcaa aagattgtcg acatgtggaa ttgcctctta tgccattagc caagattacc
     1441 atattctttt cttcctgttg ggaattggaa tcagcaagga gctaagaatg atttttcatt
     1501 gcttcattga aacctggcct tggcccaacc aaacaaaagg aataaagagt gtccaagtgc
     1561 tctactcacg cctgataaaa tacctgttgt gtgggaaggt gtccatgcaa agatgagttg
     1621 tagtgaacct atacggaatt gctgtattgc attatttttc aacatacagt gtctacttgg
     1681 ttatctggaa aacatgtgtc tactgggtgc tggagttttg ttagggcatg gtgacttcct
     1741 gggtttccct cctaggcttt gagttgcagt tagctgaaga gttagttcca ctccacccca
     1801 ccttctgaag gatcatactg gttatcacat ggctccaaac agaaaatctc tgctttgttt
     1861 atcagactag ttggcatagt caacacacct gagaagaaac cgggaaagtt ggaggaacaa
     1921 gaaacttctg tatcattcta aatttggagg aaacaccagg acttctgctc taacaagctt
     1981 ttctagcctt gttcttttaa aggttgtgtt taagggcttg aggattggca gcacactgta
     2041 atccatcacc ctctttctcc aaaaattaaa ttaattgtaa ccttcctaag atacccaagt
     2101 aatggagaag gcctaatgag catgcccaag gcttgtgtga tacaatacag gacaactatg
     2161 tttttttgtt ttgttttgtt ttgttttcct tctctgtgtt taaaagggaa ttctgcatgt
     2221 ctagggccac agttaatgta ttcttaccca tttgaagaga ggaagacaca ctggagtctt
     2281 taagttttac tccatttcta aagtcatgca tttgaacaga aaaaaatttg aaaaagatac
     2341 gggatcaccc ttaatttaga atatataaga cttaggttgc attaagagag ttttagaaaa
     2401 catttgaaaa tgaatgaata tgcagaaaag taataccatt ccatccttaa aaatattaaa
     2461 ccatatagat atataacctt gccaaaatct tagtaatatt ttgcaatttg gttcataatt
     2521 tgtgacatgt ggcatattaa attgcattaa acttttattt caagaatgat tgatgattaa
     2581 gttcatacac aggtttgtgg tttgtactaa attacgggtt ttttctttat tattcatact
     2641 tgtgtctccc tcactttcat gatcttgaaa cttttcaggg aactgagcca tgtccagact
     2701 taaggcttca gaaaagttga agtcaagagt ggtatgagta gaagaacaga taggtcaaga
     2761 gagctcttat ttcaggaagg gatatgctta catcttaaag acttttcatc agttactgat
     2821 gatccatgga tttcaacttc atgtgaggga caagaagtag tccatgggat tctactttca
     2881 gtgatattac caaggcataa caactcatcc taagggaatg tgtaccaaca cactgcatac
     2941 atgaccattt ccaacttgtc ctctttaaat tctcacatct cttaaaaaaa aaagcatttc
     3001 tttcattttt gctagtttcc cttttgtact tttgttctaa ttttttccac actttgtttc
     3061 ataaagtttg caagagcatc accaagtccc ataaacaata taagaagatt tgtaacatct
     3121 acaaaatgaa tatgaaaaga aagaatgaaa tatttaaaat gttttagtta taagggtttt
     3181 ctgaggggtt tcttctcatg gcaactgtaa ctgtgggctg tgtatcctac ttttatggac
     3241 tggattatat ctttcggatt ttatatatgc ttatgcaaag tagttatcta tttctcaatg
     3301 ttattataaa tggcccatct atttctatgg gcctacatat atagaaaact gttatctata
     3361 acatagacat gcaaaattct gcaatttata atgcattatt gatcaggttt tacagaataa
     3421 atgaaaagtc ttc
//
