LOCUS       NM_031999               2996 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Mus musculus G protein-coupled receptor 137B (Gpr137b), mRNA.
ACCESSION   NM_031999 XM_904178 XM_918695 XM_918702 XM_918724 XM_918739
VERSION     NM_031999.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2996)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2996)
  AUTHORS   Qu,W., Zhou,X., Jiang,X., Xie,X., Xu,K., Gu,X., Na,R., Piao,M.,
            Xi,X., Sun,N., Wang,X., Peng,X., Xu,J., Tian,J., Zhang,J., Guo,J.,
            Zhang,M., Zhang,Y., Pan,Z., Wang,K., Yu,B., Sun,B., Li,S. and
            Tian,J.
  TITLE     Long Noncoding RNA Gpr137b-ps Promotes Advanced Atherosclerosis via
            the Regulation of Autophagy in Macrophages
  JOURNAL   Arterioscler Thromb Vasc Biol 43 (11), e468-e489 (2023)
   PUBMED   37767704
  REMARK    GeneRIF: Long Noncoding RNA Gpr137b-ps Promotes Advanced
            Atherosclerosis via the Regulation of Autophagy in Macrophages.
            Erratum:[Arterioscler Thromb Vasc Biol. 2024 Mar;44(3):e116. doi:
            10.1161/ATV.0000000000000170. PMID: 38381855]
REFERENCE   3  (bases 1 to 2996)
  AUTHORS   Hu,Y., Wang,Y., Zhang,X., Jin,X., Pei,W., Wang,L., Zhang,Y. and
            Jialin,Gao.
  TITLE     TM7SF1, an important autophagy regulatory protein in mouse
            podocytes
  JOURNAL   Biochem Biophys Res Commun 528 (1), 213-219 (2020)
   PUBMED   32482387
  REMARK    GeneRIF: TM7SF1, an important autophagy regulatory protein in mouse
            podocytes.
REFERENCE   4  (bases 1 to 2996)
  AUTHORS   Urso,K., Caetano-Lopes,J., Lee,P.Y., Yan,J., Henke,K., Sury,M.,
            Liu,H., Zgoda,M., Jacome-Galarza,C., Nigrovic,P.A., Duryea,J.,
            Harris,M.P. and Charles,J.F.
  TITLE     A role for G protein-coupled receptor 137b in bone remodeling in
            mouse and zebrafish
  JOURNAL   Bone 127, 104-113 (2019)
   PUBMED   31173907
  REMARK    GeneRIF: A role for G protein-coupled receptor 137b in bone
            remodeling in mouse and zebrafish.
REFERENCE   5  (bases 1 to 2996)
  AUTHORS   Islam,Z., Inui,T. and Ishibashi,O.
  TITLE     Gpr137b is an orphan G-protein-coupled receptor associated with M2
            macrophage polarization
  JOURNAL   Biochem Biophys Res Commun 509 (3), 657-663 (2019)
   PUBMED   30595385
  REMARK    GeneRIF: Gpr137b is involved in interleukin-4-induced M2 macrophage
            polarization. Gpr137b is not involved in lipopolysaccharide-induced
            M1 macrophage polarization.
REFERENCE   6  (bases 1 to 2996)
  AUTHORS   Gwynn,B., Ciciotte,S.L., Hunter,S.J., Washburn,L.L., Smith,R.S.,
            Andersen,S.G., Swank,R.T., Dell'Angelica,E.C., Bonifacino,J.S.,
            Eicher,E.M. and Peters,L.L.
  TITLE     Defects in the cappuccino (cno) gene on mouse chromosome 5 and
            human 4p cause Hermansky-Pudlak syndrome by an AP-3-independent
            mechanism
  JOURNAL   Blood 96 (13), 4227-4235 (2000)
   PUBMED   11110696
REFERENCE   7  (bases 1 to 2996)
  AUTHORS   Spangenberg,C., Winterpacht,A., Zabel,B.U. and Lobbert,R.W.
  TITLE     Cloning and characterization of a novel gene (TM7SF1) encoding a
            putative seven-pass transmembrane protein that is upregulated
            during kidney development
  JOURNAL   Genomics 48 (2), 178-185 (1998)
   PUBMED   9521871
REFERENCE   8  (bases 1 to 2996)
  AUTHORS   Orwig,K.E., Ishimura,R., Muller,H., Liu,B. and Soares,M.J.
  TITLE     Identification and characterization of a mouse homolog for
            decidual/trophoblast prolactin-related protein
  JOURNAL   Endocrinology 138 (12), 5511-5517 (1997)
   PUBMED   9389538
REFERENCE   9  (bases 1 to 2996)
  AUTHORS   Zhang,Z.X., Leclerc,D., Gravel,R. and Rozen,R.
  TITLE     The methionine synthase (Mtr) gene maps to proximal mouse
            chromosome 13
  JOURNAL   Mamm Genome 8 (10), 787-788 (1997)
   PUBMED   9321480
REFERENCE   10 (bases 1 to 2996)
  AUTHORS   Chambers,D.M. and Abbott,C.M.
  TITLE     Isolation and mapping of novel mouse brain cDNA clones containing
            trinucleotide repeats, and demonstration of novel alleles in
            recombinant inbred strains
  JOURNAL   Genome Res 6 (8), 715-723 (1996)
   PUBMED   8858346
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB847916.1, AK080884.1 and BU758113.1.
            
            On Jun 6, 2007 this sequence version replaced NM_031999.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK080884.1, SRR1660811.83797.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-56                BB847916.1         7-62
            57-2978             AK080884.1         10-2931
            2979-2996           BU758113.1         1-18                c
FEATURES             Location/Qualifiers
     source          1..2996
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 5.24 cM"
     gene            1..2996
                     /gene="Gpr137b"
                     /gene_synonym="C730041E01; D13Abb1e; Tm7sf1"
                     /note="G protein-coupled receptor 137B"
                     /db_xref="GeneID:83924"
                     /db_xref="MGI:MGI:1891463"
     exon            1..500
                     /gene="Gpr137b"
                     /gene_synonym="C730041E01; D13Abb1e; Tm7sf1"
                     /inference="alignment:Splign:2.1.0"
     exon            501..550
                     /gene="Gpr137b"
                     /gene_synonym="C730041E01; D13Abb1e; Tm7sf1"
                     /inference="alignment:Splign:2.1.0"
     exon            551..773
                     /gene="Gpr137b"
                     /gene_synonym="C730041E01; D13Abb1e; Tm7sf1"
                     /inference="alignment:Splign:2.1.0"
     exon            774..923
                     /gene="Gpr137b"
                     /gene_synonym="C730041E01; D13Abb1e; Tm7sf1"
                     /inference="alignment:Splign:2.1.0"
     exon            924..1052
                     /gene="Gpr137b"
                     /gene_synonym="C730041E01; D13Abb1e; Tm7sf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1053..1177
                     /gene="Gpr137b"
                     /gene_synonym="C730041E01; D13Abb1e; Tm7sf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1178..2981
                     /gene="Gpr137b"
                     /gene_synonym="C730041E01; D13Abb1e; Tm7sf1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1453..1458
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gpr137b"
                     /gene_synonym="C730041E01; D13Abb1e; Tm7sf1"
                     /note="hexamer: AATAAA"
     polyA_site      1479
                     /gene="Gpr137b"
                     /gene_synonym="C730041E01; D13Abb1e; Tm7sf1"
                     /note="major polyA site"
     regulatory      2931..2936
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gpr137b"
                     /gene_synonym="C730041E01; D13Abb1e; Tm7sf1"
                     /note="hexamer: AATAAA"
     regulatory      2958..2963
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gpr137b"
                     /gene_synonym="C730041E01; D13Abb1e; Tm7sf1"
                     /note="hexamer: AATAAA"
     polyA_site      2965
                     /gene="Gpr137b"
                     /gene_synonym="C730041E01; D13Abb1e; Tm7sf1"
     polyA_site      2981
                     /gene="Gpr137b"
                     /gene_synonym="C730041E01; D13Abb1e; Tm7sf1"
                     /note="major polyA site"
ORIGIN      
        1 atgtggtgcg gcgggaggaa gtgcggcttg ttttcccggc taggctctgg agcggcgggc
       61 gcggcgcgat gcgcgggtac ccgggagcga acggctgcga gccctgatga agctcgagca
      121 gccccagcct gatggaggcg cctccgtggg agccggtgcg caatgactcc ctgcctccca
      181 cgctgagccc cgcggtgccg ccctacgtga agctcggcct caccgcggtc tacaccgtct
      241 tctacgcgct cctcttcgtg ttcatctatg cgcagctctg gctggtgctg cgctaccgtc
      301 acaagcggct cagctaccag agcgtcttcc tcttcctttg cctcttctgg gcctcgctgc
      361 gtaccgtgct cttctccttt tacttccgag acttcgtggc agccaactcg ttcagcccct
      421 tcgtcttctg gctgctctac tgcttccccg tgtgtctaca gttcttcacc ctcacgctca
      481 tgaacttgta cttcacgcag gtgattttca aggccaagtc aaaatattct ccagagctac
      541 tcaaataccg gttacccctc tacctggcct cacttttcat cagcctcgtt ttcctgttgg
      601 tgaatctgac ctgtgctgtg ctggtgaaga cgggagactg ggacaggaag gttatcgtct
      661 ctgtgagagt ggccatcaat gacacactct ttgtgctgtg tgctatctct ctctccatct
      721 gcctctacaa aatctccaag atgtccctgg ccaacatcta cttggagtca aagggctcat
      781 cagtgtgtca ggtaactgcc attggtgtca ccgtcatctt gctctacacc tctcgggcct
      841 gctacaacct gttcatcttg tcattttctc agatcaagaa cgtccattcc tttgattatg
      901 actggtacaa tgtatccgac caggcagatc tgaagagcca gctgggtgac gccggctacg
      961 tagtgtttgg cgtggtgctt ttcgtgtggg agctcctacc caccaccttg gtggtttatt
     1021 tcttccgagt cagaaatccc acgaaggatc ttaccaatcc tgggatggtc cccagccatg
     1081 gattcagtcc cagatcttac ttctttgaca acccccgaag atatgacagt gatgatgacc
     1141 ttgcctggaa cattgcccct cagggacttc agggaagttt tgctccagac tactatgatt
     1201 ggggacaaca aaataacagc ttcctggcac aagcaggaac tttgcatcaa gactccactt
     1261 tggatccaga caaagcaagc caagggtagc agcagctgac acagccctat ggaagagttc
     1321 tctgttgaaa gccttcagcc agacagaccg gatgacagct gagttgctaa ggcagttttc
     1381 cttaggaaac agaactctag tttttgctat agctttctca tggctccaca gggctaagca
     1441 ataatttaga gcaataaact ctttagtact agcagagaat ctggctattt cagtgggtat
     1501 aatttaaact tataaaagag gttctgtact tttataaaga tgtattttat ataacttaaa
     1561 tactaatgct aaagtatact aggtttttcc ttgattgtta attgcaacgt atgttgtagt
     1621 ttgcacagac tttcatgcat aattcacttt aaaacgtata gaatacgtgg tctaatagtt
     1681 taaagctttg gggaaagttt ccacaaatct tacctctgaa ggtccctctt gtgagtgcca
     1741 cgtggtgggc tcctttcacc gccactcaag cattccaagt tcaggagaag cagagtacca
     1801 tggtctgtac gtaacaggct caacagcagc agcagcagca gcagcagcag cagcaatttc
     1861 tcgtaaactc tgtcctaagc ctggtccttc ttcatctgaa agcactacta caagcactcc
     1921 agtaacaagt ggatactgtt aagatgtagt tgctgacact attaaacctc ctctgctgtg
     1981 tgtgtagcca ttttgtagag ttttcttcag cccggtgtaa ctgaatactc actacctcag
     2041 tacctcagta ggatgcaagg actgtgcctt ctttgactca gccagtgctt gctatagtca
     2101 ggctacaagc caagaggtcc ccacagagta ttaacaataa atacttctgg ccttcaagct
     2161 ctaaaggatt gcagactcct gacagctttt ctgtaagaca tgcctgtcat ttgtatgagg
     2221 ctgacacggg gctcactgcc tgttattttt agatagtgtt ctattaaaag ctatgtgtat
     2281 gagaaagtag gctctgccta cgtggcggca gcatccccat atcagccaga gagtgttcca
     2341 gacagtggtc ctcttgtgcc atctccgtgc tgtcctggga aaacgctgga acaacgtggc
     2401 cctcctggag gccggatgct ctggcttctt ctggtcctat aggtcacaga gccacgccca
     2461 ctttctccca ttttgttata tttaagattg ggagcccagt ttccagtggg ttgtaatggg
     2521 gtcttcgttg tacagaggac gacgtggagg aacttgcgca gccccgcccc acaccctgcc
     2581 tttgggtttg agtaaacatc tgggttgcaa gccatttaaa attgcttctt tgccagggtg
     2641 aattctggca aagcctacac aaatcgcctg tacgatagca ctgtataaaa gtttatctgt
     2701 caccatacct gcaatgattt ggctgttgca gccagtgccc acagctcctg tgtccttgtc
     2761 tctagcaggg cggtacctgt cagcagccaa gggcaaggct tgctggaaag cacagcctca
     2821 ttaaggctgt tctgtttgca cccattttgt agcacatgca cactttacag ttggtgaatg
     2881 ctgggcgtct gttttcttac agtaacaagc aagctatcat ccatttttac aataaagttg
     2941 tcagcattca tgtcagcaat aaaaagacta cagctcttaa aaaaaaaaaa aaaaaa
//
