LOCUS       NM_175380               4393 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus glycerol-3-phosphate dehydrogenase 1-like (Gpd1l),
            mRNA.
ACCESSION   NM_175380 XM_981192
VERSION     NM_175380.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4393)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4393)
  AUTHORS   Liu,M., Sanyal,S., Gao,G., Gurung,I.S., Zhu,X., Gaconnet,G.,
            Kerchner,L.J., Shang,L.L., Huang,C.L., Grace,A., London,B. and
            Dudley,S.C. Jr.
  TITLE     Cardiac Na+ current regulation by pyridine nucleotides
  JOURNAL   Circ Res 105 (8), 737-745 (2009)
   PUBMED   19745168
  REMARK    GeneRIF: Mutations of GPD1-L may downregulate Na(v)1.5 by altering
            the oxidized to reduced NAD(H) balance.
REFERENCE   3  (bases 1 to 4393)
  AUTHORS   London,B., Michalec,M., Mehdi,H., Zhu,X., Kerchner,L., Sanyal,S.,
            Viswanathan,P.C., Pfahnl,A.E., Shang,L.L., Madhusudanan,M.,
            Baty,C.J., Lagana,S., Aleong,R., Gutmann,R., Ackerman,M.J.,
            McNamara,D.M., Weiss,R. and Dudley,S.C. Jr.
  TITLE     Mutation in glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L)
            decreases cardiac Na+ current and causes inherited arrhythmias
  JOURNAL   Circulation 116 (20), 2260-2268 (2007)
   PUBMED   17967977
REFERENCE   4  (bases 1 to 4393)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC127573.4, BC138980.1, AK172886.1 and BY369485.1.
            
            On Sep 9, 2009 this sequence version replaced NM_175380.4.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK172886.1, AK145475.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-172               AC127573.4         42864-43035
            173-1348            BC138980.1         1-1176
            1349-4390           AK172886.1         1294-4335
            4391-4393           BY369485.1         391-393
FEATURES             Location/Qualifiers
     source          1..4393
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 65.47 cM"
     gene            1..4393
                     /gene="Gpd1l"
                     /gene_synonym="2210409H23Rik; D9Ertd660e"
                     /note="glycerol-3-phosphate dehydrogenase 1-like"
                     /db_xref="GeneID:333433"
                     /db_xref="MGI:MGI:1289257"
     exon            1..317
                     /gene="Gpd1l"
                     /gene_synonym="2210409H23Rik; D9Ertd660e"
                     /inference="alignment:Splign:2.1.0"
     CDS             271..1326
                     /gene="Gpd1l"
                     /gene_synonym="2210409H23Rik; D9Ertd660e"
                     /EC_number="1.1.1.8"
                     /codon_start=1
                     /product="glycerol-3-phosphate dehydrogenase 1-like
                     protein"
                     /protein_id="NP_780589.3"
                     /db_xref="CCDS:CCDS23598.1"
                     /db_xref="GeneID:333433"
                     /db_xref="MGI:MGI:1289257"
                     /translation="MAAAPLKVCIVGSGNWGSAVAKIIGSNVKTLQKFSSTVKMWVFE
                     ETVNGRKLTDIINNDHENVKYLPGHKLPENVVAVPNLSEAVQDADLLVFVIPHQFIHK
                     ICDEITGRVPEKALGITLIKGIDEGPDGLKLISDIIREKMGIDISVLMGANIASEVAA
                     EKFCETTIGSKVMQNGLLFKELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDG
                     LRCGDNTKAAVIRLGLMEMIAFAKIFCKGQVSTATFLESCGVADLITTCYGGRNRRVA
                     EAFARTGKTIEELEKELLNGQKLQGPQTSAEVYRILRQKGLLDKFPLFTAVYQICYEG
                     RPVTQMLSCLQSHPEHI"
     exon            318..495
                     /gene="Gpd1l"
                     /gene_synonym="2210409H23Rik; D9Ertd660e"
                     /inference="alignment:Splign:2.1.0"
     exon            496..636
                     /gene="Gpd1l"
                     /gene_synonym="2210409H23Rik; D9Ertd660e"
                     /inference="alignment:Splign:2.1.0"
     exon            637..775
                     /gene="Gpd1l"
                     /gene_synonym="2210409H23Rik; D9Ertd660e"
                     /inference="alignment:Splign:2.1.0"
     exon            776..888
                     /gene="Gpd1l"
                     /gene_synonym="2210409H23Rik; D9Ertd660e"
                     /inference="alignment:Splign:2.1.0"
     exon            889..1122
                     /gene="Gpd1l"
                     /gene_synonym="2210409H23Rik; D9Ertd660e"
                     /inference="alignment:Splign:2.1.0"
     exon            1123..1229
                     /gene="Gpd1l"
                     /gene_synonym="2210409H23Rik; D9Ertd660e"
                     /inference="alignment:Splign:2.1.0"
     exon            1230..4393
                     /gene="Gpd1l"
                     /gene_synonym="2210409H23Rik; D9Ertd660e"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3933..3938
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gpd1l"
                     /gene_synonym="2210409H23Rik; D9Ertd660e"
                     /note="hexamer: AATAAA"
     polyA_site      3957
                     /gene="Gpd1l"
                     /gene_synonym="2210409H23Rik; D9Ertd660e"
                     /note="major polyA site"
     regulatory      4362..4367
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gpd1l"
                     /gene_synonym="2210409H23Rik; D9Ertd660e"
                     /note="hexamer: AATAAA"
     polyA_site      4386
                     /gene="Gpd1l"
                     /gene_synonym="2210409H23Rik; D9Ertd660e"
ORIGIN      
        1 gtggttcctg ggagtggtgg ggcgggtcct ccgggctgtc agctgtggcc ctaggcgcct
       61 aggcagggtg gcggtggcca ttggcggaca ggagggcggg gcggggtcgc ccggagcgcc
      121 tatactaggc cgttcctgtg gaggtgagca gccggcctgg gaggcacagt gtgtgttgca
      181 gcgatccgac ttgcagcagc gatccgactt gcagcagcga tccggcttgg ccctgagagg
      241 aaggctgtgc agcagcgatc cggcttggcc atggcagcgg cgcctctgaa agtgtgcatc
      301 gtgggctcgg ggaactgggg atcagctgtt gcaaaaatca tcggcagcaa cgtgaagacc
      361 ctgcagaaat tctcctccac cgtcaagatg tgggtctttg aggagaccgt gaacgggagg
      421 aagctgacag acataatcaa caatgaccac gaaaacgtga aatatctccc aggacacaag
      481 ctgccagaga atgtggtcgc tgtcccaaac ctcagcgaag ccgtgcagga cgcggacctg
      541 ctggtgttcg tcatccctca ccagttcatc cacaagatct gcgatgagat cacgggcagg
      601 gtgcccgaga aggccctggg gatcaccctc atcaagggca tagatgaggg ccccgacggg
      661 ctgaagctaa tctccgacat catccgagag aagatgggga tcgacatcag tgtgctgatg
      721 ggggccaaca tcgccagtga ggtcgctgcg gagaagttct gcgagaccac cattggcagc
      781 aaagtgatgc agaacggcct tctcttcaaa gagctgctgc agacgcccaa cttcagaatc
      841 actgtggtag acgatgcaga caccgtggag ctttgcggtg ctcttaagaa cattgttgct
      901 gtgggagctg gcttctgcga cggcctccgc tgtggggaca acaccaaggc ggccgtcata
      961 cgcctgggcc tcatggaaat gatcgctttc gccaagatct tctgtaaggg ccaggtgtcc
     1021 acggccacct tcttggagag ctgcggggtg gctgacctca tcaccacctg ctacggaggg
     1081 cggaaccgca gggtggcaga ggccttcgcc aggactggga agaccatcga agagctggag
     1141 aaggagctgc tgaacgggca gaagctgcag ggacctcaga cctctgcgga ggtgtaccgc
     1201 atcctcaggc agaaggggct gctggacaag tttcccctct tcactgcagt gtatcagatc
     1261 tgctatgaag gcaggcctgt cacgcagatg ctgtcctgcc tgcagagcca cccagagcac
     1321 atctgaagga gtcaggcagc catcaggaac agctctgctg tgcccactgg aggaatccgg
     1381 ggcttggcag tgggatcctg ctgaactgta cttcgaatac atccaaattg ttacagcttt
     1441 gtctctgtgc caggagaagc actcctccac tggctaagat gtgtcgggta acaactacag
     1501 acacacacgc acatgagtga atgtgtgtga gagtgtttgt gtgtgtgtat gtgtgtgtgt
     1561 gtatatatac aagtgtgcac ctttctcatt ctgtgagtgt ttctctgaac ccaaatcagg
     1621 tgtctattga tcacatttta aatttcccct ccagggcagc ttgtgaagtt agaactaact
     1681 cagctaaatg ttatggctgt gactcattta tatgcaaggg aagggaggaa ctgggttttt
     1741 ttccctctga aacagctatc cagcattaaa aacgtctgca tatatgtgtg tttgaagacc
     1801 accacacttt taaacagcat ctcagagcca gcagcatgaa ctcctgggtt gtggattgac
     1861 ggctaaacaa tcaggtgttt taattagata ctccacagac aggtgtcttc ttgatacaga
     1921 gaccacattc cttgcctctt tcctcttcat ttgctgctag aatgggcttt catacagacc
     1981 cagcaaggca gaggaggaac atccttgcag tggctgggga cacttcatta tgctcattgc
     2041 taggtggact ttttttttgc agctgtgtct cttcaggctt gtggaaggaa ccctcaaggg
     2101 ggccactgtc acttctcatg taagaagcca tagctgtacc tggtcacctg gggacatggg
     2161 gacattcctc catccctcca ggatgggacc tgcgaggatg tccctgggcc tctctgacct
     2221 gctgtttgta ggaatgatgt gcctttcctg agggccagga gggctacttg ccttggagat
     2281 ttgtgtggca aagagtggga aagtcaccac ccacgtggtg tccccagtca gcaggggcat
     2341 ttcactcagc aggatcccac tgccaagccc cagatacctg gtgttcctcc aggaatccag
     2401 tgtttccaca tgccttctat gcatttcgga tgctcactac agcagagagc cactgcacta
     2461 gagaatttac agcctttgct gaacaatgct ctataagaga caagtgtcct ggagtctcct
     2521 ggctaagcca ggtggaccct ggaatggcca agtaagtttg gccatcccag ctgcctgact
     2581 tttcacactt tcctagagtg gggagggatc ctggatgcta ggaacccata aagctaatac
     2641 gtcccaaaca cattagacta tgagagtctt gtttttctta actagaatat taattaaaat
     2701 ttctagagaa tactcctata gagtgaggtg accctcactc tccacaggaa ttcaggatga
     2761 ctaacttcct gtgagagttc tatgtagcct gggctggcct tgaatttgtc accttcttgc
     2821 ctctgtctcc tgagtggcct gggctttgca gttctggcct aacccctgag aaagctttca
     2881 ggatgcaggg tcaggcacag acaaggggat gtcgacctca gtgaaacgca cactatatgg
     2941 agtgagtgct ttggatgcta gaattagaac acaaatgatt ttatctttat ttaaaaacca
     3001 ggcgtcccac gggggtggaa agagcacacg gaggtcattg tcctgtgctt tagcctatga
     3061 gagtttccac ttcccctccc tcctcctggg tttggttgcc cccaccctac tctacatccc
     3121 ttctataact gaaaatgatt gtaaaataaa tttttatgag aattttaaaa actgtccaag
     3181 aagacttttt ggagcattat aaagtcccac acctaaaacg cacagcaggc tgaatatttc
     3241 agttttctta atgatgtcaa tcaatttttt cttgcctcct aagtctttta aaaaacgaaa
     3301 ctctgtacat atgtaacaaa gagttacttt ttaagatatc caaagggctg agagctaccg
     3361 tggtgtctac aaagtagcac aatgcagagt tgttgacgtg ttttgcatcc tcgtgtacat
     3421 tcaccctctc tctggccttg tacttccgct tcttccttcc ctaatgaatg accttactta
     3481 ctgactgaca tccccctgaa gtcagctgat gtgcttataa cccacccagg agggaaacag
     3541 gtaaatttct tgtttgtgct ctgaaggcca gaggcattgc tgtatgcgtt acctgttttt
     3601 gtaaccttgt aaccacctgc tgattggtgt ttcttggcga taggctcaga gacacctaga
     3661 ttagaaactt cacctgtgaa tgtaaaacta agctcttgcc ttgctactct cctctccacc
     3721 gcagttttgg acaaatcttt ggaaacccac ccctggggca gagcctgcct tctggtgttt
     3781 tcatagctgg cctaagaagg gtgctgtggt gagatcgcag tgtctaaaca gaattgtttc
     3841 tctgccactt ctgactggct ggcctcctac ttccatatgt actgtatttg tttacggact
     3901 gtaggtgggt gtatagtgta aaggcttggt ttaataaaca caacctctca gacctgttcc
     3961 atggagccta tttttccttt cttgttttta taaattatta ttggggtgtg ctgtacaaaa
     4021 ttgtgtctct gttcttacct acccaaggca ttctttgatt ggctttaata aaaaatcaga
     4081 tggccgatta gctgggcatg aagtggaagg tgggacttcc tgggagggag aaaggaactc
     4141 tggaaagaaa gaaggaggca cgaggggaga caaatatgat tttggtacta gaaagtagcc
     4201 acatggctgg atagggctag gtggctgggt taacttagat gagctagttg agagtctgcc
     4261 cagctaaggc ctaaagcttt gaaatattaa aagtctctat ggttatttgg ggaaaattgg
     4321 ataaggaata attgccattg tattcatttc cagcattaat taataaatac agaattttaa
     4381 tatttatatt ata
//
