LOCUS       NM_032460               1304 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus G patch domain and ankyrin repeats 1 (Gpank1),
            transcript variant 1, mRNA.
ACCESSION   NM_032460
VERSION     NM_032460.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1304)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1304)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   3  (bases 1 to 1304)
  AUTHORS   Arora,H., Boulberdaa,M., Qureshi,R., Bitirim,V., Messadeq,N.,
            Dolle,P. and Nebigil,C.G.
  TITLE     Prokineticin receptor 1 is required for mesenchymal-epithelial
            transition in kidney development
  JOURNAL   FASEB J 30 (8), 2733-2740 (2016)
   PUBMED   27084889
REFERENCE   4  (bases 1 to 1304)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   5  (bases 1 to 1304)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   6  (bases 1 to 1304)
  AUTHORS   Lanning,D. and Lafuse,W.P.
  TITLE     Localization of the casein kinase II beta-subunit gene within the
            mouse H-2 complex class III region and comparison of expression
            with Bat genes
  JOURNAL   Mamm Genome 8 (7), 519-521 (1997)
   PUBMED   9196000
REFERENCE   7  (bases 1 to 1304)
  AUTHORS   Dagenais,S.L. and Nakamura,I.
  TITLE     A physical map of the mouse H2 Bat5/Db interval
  JOURNAL   Mamm Genome 8 (1), 39-41 (1997)
   PUBMED   9021146
REFERENCE   8  (bases 1 to 1304)
  AUTHORS   Snoek,M., van Vugt,H. and Groot,P.C.
  TITLE     New microsatellite size variants as markers for a cross-over
            hotspot in the C4-H-2D region
  JOURNAL   Mamm Genome 5 (3), 174-176 (1994)
   PUBMED   8199408
REFERENCE   9  (bases 1 to 1304)
  AUTHORS   Gasser,D.L., Sternberg,N.L., Pierce,J.C., Goldner-Sauve,A.,
            Feng,H., Haq,A.K., Spies,T., Hunt,C., Buetow,K.H. and Chaplin,D.D.
  TITLE     P1 and cosmid clones define the organization of 280 kb of the mouse
            H-2 complex containing the Cps-1 and Hsp70 loci
  JOURNAL   Immunogenetics 39 (1), 48-55 (1994)
   PUBMED   7993390
REFERENCE   10 (bases 1 to 1304)
  AUTHORS   Lafuse,W.P., Lanning,D., Spies,T. and David,C.S.
  TITLE     PFGE mapping and RFLP analysis of the S/D region of the mouse H-2
            complex
  JOURNAL   Immunogenetics 36 (2), 110-116 (1992)
   PUBMED   1351875
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC120637.1 and BY606764.1.
            
            On Jun 18, 2008 this sequence version replaced NM_032460.1.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BG067894.2, BC120637.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1210              BC120637.1         2-1211
            1211-1304           BY606764.1         282-375
FEATURES             Location/Qualifiers
     source          1..1304
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 18.59 cM"
     gene            1..1304
                     /gene="Gpank1"
                     /gene_synonym="Bat-4; Bat4; D17H6S54E; G5"
                     /note="G patch domain and ankyrin repeats 1"
                     /db_xref="GeneID:81845"
                     /db_xref="MGI:MGI:2148975"
     exon            1..708
                     /gene="Gpank1"
                     /gene_synonym="Bat-4; Bat4; D17H6S54E; G5"
                     /inference="alignment:Splign:2.1.0"
     CDS             35..1153
                     /gene="Gpank1"
                     /gene_synonym="Bat-4; Bat4; D17H6S54E; G5"
                     /note="isoform 1 is encoded by transcript variant 1; HLA-B
                     associated transcript 4; protein BAT4; G patch domain and
                     ankyrin repeats-containing protein 1; G patch domain and
                     ankyrin repeat-containing protein 1"
                     /codon_start=1
                     /product="G patch domain and ankyrin repeat-containing
                     protein 1 isoform 1"
                     /protein_id="NP_115849.2"
                     /db_xref="CCDS:CCDS28685.1"
                     /db_xref="GeneID:81845"
                     /db_xref="MGI:MGI:2148975"
                     /translation="MVGSLACHILALPSLHFLVSLTGMSRPSFIEFTPAADSSDLWKD
                     GQQQPQQEKAEPVLDGAAARAFYEALIADDSSSSKPQRAEPMRERKKKRRRVTREPAA
                     AGVPRQGRALEDEDRMAQWILLAAQNGDLTELRRLLEPQEAGGAGGNINARDAFWWTP
                     LMCAARAGQGAAVRYLLGRGAAWVGVCDLGGRDAAQLAEEAGFPEVARMVRESHGETR
                     SPENQNRSTPSSSQFCEDCGAHFEDSNHHTSTAHLLSLSRRPQPSNLPLGVPTSSPGF
                     RLLLRGGWEPGMGLGPRGEGRANPIPTILKRDQEGLGYRSPPQPRVTHFAARDTRAVS
                     GRERVPRVATLSQRENRRQEEKGRAWERDLRLYMNLEF"
     exon            709..1304
                     /gene="Gpank1"
                     /gene_synonym="Bat-4; Bat4; D17H6S54E; G5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1285..1290
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gpank1"
                     /gene_synonym="Bat-4; Bat4; D17H6S54E; G5"
                     /note="hexamer: AATAAA"
     polyA_site      1304
                     /gene="Gpank1"
                     /gene_synonym="Bat-4; Bat4; D17H6S54E; G5"
                     /note="major polyA site"
ORIGIN      
        1 ggtggtgctg gtcatcttca caatagctac ctgaatggtt ggatcgcttg cttgtcacat
       61 ccttgccttg cccagtcttc attttcttgt ttctctcaca ggcatgtcta ggccatcctt
      121 catcgaattt accccagcgg ctgactccag tgacctctgg aaggatgggc agcagcaacc
      181 acagcaggag aaagcagagc ctgtcctgga cggggctgct gcccgggctt tctatgaggc
      241 tctaatcgca gatgacagta gttcctctaa gccccagaga gctgaaccta tgagggagag
      301 gaagaagaag agaagaagag tgactaggga gcctgcagca gcaggagtcc ccagacaagg
      361 aagagcactt gaggatgaag acaggatggc ccagtggatc ctgctggcag cccagaatgg
      421 ggatctgaca gaactccgga ggctgctaga accccaagag gcagggggag ctggagggaa
      481 tatcaatgct cgtgatgcct tctggtggac tcccttgatg tgtgctgccc gagcaggcca
      541 gggcgccgct gtgcgctatc tcctgggccg aggagctgcc tgggttggag tctgtgacct
      601 gggaggcaga gatgctgccc agctggctga agaagcaggc ttccctgagg tagcccgtat
      661 ggtcagagag agtcatggag agacaaggag ccctgagaac cagaaccgat ctaccccctc
      721 ctcgtcccag ttctgtgagg actgtggtgc ccactttgaa gactccaacc accacacatc
      781 tactgctcac ctgctgtcac tgtccaggag accccagccc tccaaccttc cccttggggt
      841 gcccacttcc agtcctggct tcaggctact gctgagaggt ggctgggaac caggaatggg
      901 gctaggaccc cggggtgaag gccgtgccaa ccctatcccc actatcctca agagggacca
      961 ggaaggattg ggttatagat ccccacccca accccgagtc acacactttg cagcgcggga
     1021 tacccgggct gtgtctggga gagagagagt ccctcgagtt gccacactga gtcagaggga
     1081 gaacagaagg caagaagaaa agggcagagc ctgggagcga gatctaagac tgtacatgaa
     1141 cctcgagttc tgactgatat ggactggccc tggtctgtca ctcgctggac ttgggcctct
     1201 gacttggaca cttggacttc cgaaccctta ggccttagct gttgggctct gattttagag
     1261 agaagggcgg agagttggga gataaataaa cttccttcct tgtg
//
