LOCUS       NM_010331               2036 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus GPI anchor attachment protein 1 (Gpaa1), mRNA.
ACCESSION   NM_010331
VERSION     NM_010331.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2036)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2036)
  AUTHORS   Horiuchi,K., Perez-Cerezales,S., Papasaikas,P., Ramos-Ibeas,P.,
            Lopez-Cardona,A.P., Laguna-Barraza,R., Fonseca Balvis,N.,
            Pericuesta,E., Fernandez-Gonzalez,R., Planells,B., Viera,A.,
            Suja,J.A., Ross,P.J., Alen,F., Orio,L., Rodriguez de Fonseca,F.,
            Pintado,B., Valcarcel,J. and Gutierrez-Adan,A.
  TITLE     Impaired Spermatogenesis, Muscle, and Erythrocyte Function in U12
            Intron Splicing-Defective Zrsr1 Mutant Mice
  JOURNAL   Cell Rep 23 (1), 143-155 (2018)
   PUBMED   29617656
REFERENCE   3  (bases 1 to 2036)
  AUTHORS   Vainauskas,S. and Menon,A.K.
  TITLE     A conserved proline in the last transmembrane segment of Gaa1 is
            required for glycosylphosphatidylinositol (GPI) recognition by GPI
            transamidase
  JOURNAL   J Biol Chem 279 (8), 6540-6545 (2004)
   PUBMED   14660601
  REMARK    GeneRIF: a conserved proline in the last transmembrane segment of
            Gaa1 is required for glycosylphosphatidylinositol recognition by
            GPI transamidase
REFERENCE   4  (bases 1 to 2036)
  AUTHORS   Hiroi,Y., Chen,R., Sawa,H., Hosoda,T., Kudoh,S., Kobayashi,Y.,
            Aburatani,H., Nagashima,K., Nagai,R., Yazaki,Y., Medof,M.E. and
            Komuro,I.
  TITLE     Cloning of murine glycosyl phosphatidylinositol anchor attachment
            protein, GPAA1
  JOURNAL   Am J Physiol Cell Physiol 279 (1), C205-C212 (2000)
   PUBMED   10898732
REFERENCE   5  (bases 1 to 2036)
  AUTHORS   Ohishi,K., Inoue,N., Maeda,Y., Takeda,J., Riezman,H. and
            Kinoshita,T.
  TITLE     Gaa1p and gpi8p are components of a glycosylphosphatidylinositol
            (GPI) transamidase that mediates attachment of GPI to proteins
  JOURNAL   Mol Biol Cell 11 (5), 1523-1533 (2000)
   PUBMED   10793132
REFERENCE   6  (bases 1 to 2036)
  AUTHORS   Inoue,N., Ohishi,K., Endo,Y., Fujita,T., Takeda,J. and Kinoshita,T.
  TITLE     Human and mouse GPAA1 (Glycosylphosphatidylinositol anchor
            attachment 1) genes: genomic structures, chromosome loci and the
            presence of a minor class intron
  JOURNAL   Cytogenet Cell Genet 84 (3-4), 199-205 (1999)
   PUBMED   10393431
REFERENCE   7  (bases 1 to 2036)
  AUTHORS   Hiroi,Y., Komuro,I., Chen,R., Hosoda,T., Mizuno,T., Kudoh,S.,
            Georgescu,S.P., Medof,M.E. and Yazaki,Y.
  TITLE     Molecular cloning of human homolog of yeast GAA1 which is required
            for attachment of glycosylphosphatidylinositols to proteins
  JOURNAL   FEBS Lett 421 (3), 252-258 (1998)
   PUBMED   9468317
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK077518.1.
            
            On Jun 19, 2003 this sequence version replaced NM_010331.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK077518.1, AK164978.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2036
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 35.72 cM"
     gene            1..2036
                     /gene="Gpaa1"
                     /gene_synonym="mGAA1"
                     /note="GPI anchor attachment protein 1"
                     /db_xref="GeneID:14731"
                     /db_xref="MGI:MGI:1202392"
     exon            1..170
                     /gene="Gpaa1"
                     /gene_synonym="mGAA1"
                     /inference="alignment:Splign:2.1.0"
     CDS             97..1962
                     /gene="Gpaa1"
                     /gene_synonym="mGAA1"
                     /note="GAA1 protein homolog"
                     /codon_start=1
                     /product="glycosylphosphatidylinositol anchor attachment 1
                     protein"
                     /protein_id="NP_034461.1"
                     /db_xref="CCDS:CCDS37120.1"
                     /db_xref="GeneID:14731"
                     /db_xref="MGI:MGI:1202392"
                     /translation="MGLLSDPVRRRALARIVLRLNTPLCVLSYVAGIAWFLALAFPPL
                     TQRTYMSENAMGSTMVEEQFVGGDRARSFARDFAAHRKKPGALPVAWLERSMRSVGLE
                     VYTQSFSRKLPFPDETHERYMVSGTNVYGILRAPRSASTESLVLTVPCGPDATNSQAV
                     GLLLALAAHFRGQIYWAKDIIFLVTDHDLLGTEAWLEAYHDINVTGIQSSPLQGRAGA
                     IQAAVALELSSDVVTSLDVTVEGLNGQLPNLDLLNLFQTFCQKGGLLCTLQGKLQPQD
                     WTSLEGPLQGLQTLLLMVLRQASGRPHGPHGLFLRYGVEALTLRGINSFRQYKYDLAT
                     VGKALEGMFRKLNHLLERLHQSFFFYLLPALSRFVSIGLYMPATGFLLLVLGLKALEL
                     WMQLHQAGVNPEEAGKAPSPGTPLLPTQGVGLASLTAPLLISQAMGLALYFLPVLGQH
                     LATQHFPVAEAEAVVLTLLAIYVAGLALPHNTHRVVNSQVPDRGWMALKLVALIYLAL
                     QLGCIALLNFSLGFLLAATMVPAAALAKPHGPRTLYAALLVVTSPAVTLFGSLFLWRE
                     LLEVPLSLAEGWQLFLTALAQGVLEHYTYGALLFPILALGLYPCWLLFWNVLFWK"
     exon            171..350
                     /gene="Gpaa1"
                     /gene_synonym="mGAA1"
                     /inference="alignment:Splign:2.1.0"
     exon            351..462
                     /gene="Gpaa1"
                     /gene_synonym="mGAA1"
                     /inference="alignment:Splign:2.1.0"
     exon            463..610
                     /gene="Gpaa1"
                     /gene_synonym="mGAA1"
                     /inference="alignment:Splign:2.1.0"
     exon            611..712
                     /gene="Gpaa1"
                     /gene_synonym="mGAA1"
                     /inference="alignment:Splign:2.1.0"
     exon            713..909
                     /gene="Gpaa1"
                     /gene_synonym="mGAA1"
                     /inference="alignment:Splign:2.1.0"
     exon            910..1106
                     /gene="Gpaa1"
                     /gene_synonym="mGAA1"
                     /inference="alignment:Splign:2.1.0"
     exon            1107..1260
                     /gene="Gpaa1"
                     /gene_synonym="mGAA1"
                     /inference="alignment:Splign:2.1.0"
     exon            1261..1356
                     /gene="Gpaa1"
                     /gene_synonym="mGAA1"
                     /inference="alignment:Splign:2.1.0"
     exon            1357..1547
                     /gene="Gpaa1"
                     /gene_synonym="mGAA1"
                     /inference="alignment:Splign:2.1.0"
     exon            1548..1718
                     /gene="Gpaa1"
                     /gene_synonym="mGAA1"
                     /inference="alignment:Splign:2.1.0"
     exon            1719..2036
                     /gene="Gpaa1"
                     /gene_synonym="mGAA1"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      2036
                     /gene="Gpaa1"
                     /gene_synonym="mGAA1"
                     /note="putative"
ORIGIN      
        1 gaccggaaat taaggcagca ccgggcgccg ggtccgacag gaaccctgct cttggaggtg
       61 tcaagctgcc gcgagagcag agccccgcgc cccgccatgg gtctcctgtc ggacccggtg
      121 cgccggcgcg cgctcgcccg catcgtcttg cgccttaaca cacctctctg tgtgctgagc
      181 tacgtggccg ggatcgcctg gtttctggcg ctggcttttc cgccgttaac ccagcgcact
      241 tacatgtctg agaatgccat gggctccacc atggtggagg aacagtttgt aggtggagac
      301 cgcgctcgga gctttgcccg ggacttcgct gcccaccgca agaagccggg ggctctgcca
      361 gtagcctggc tggaacggtc catgcgatcc gtagggctgg aggtctacac ccagagcttc
      421 tcccgcaaac tacccttccc ggatgagacc cacgagcgct atatggtgtc aggtaccaac
      481 gtgtatggca tcctgcgggc cccacgttct gccagtaccg agtccctggt gcttactgta
      541 ccctgtggtc cagatgccac caatagccag gctgtggggt tgttgttggc acttgctgcc
      601 catttccgag ggcagattta ctgggccaaa gatatcattt tcctggtaac agaccatgat
      661 cttctgggca ccgaggcttg gctcgaagcc taccatgaca ttaatgttac aggcatacag
      721 tcatctcccc tgcagggcag ggctggagcc atccaggctg ctgtagctct ggagctgagc
      781 agcgacgtgg tcaccagcct cgatgtgaca gtggagggac tcaacggtca gctgcccaac
      841 cttgatctgc tcaacctctt ccagaccttc tgccagaaag gggggctgtt gtgtacactc
      901 cagggcaagc tgcagcccca ggactggacg tcactcgaag ggccgttgca gggtttgcag
      961 acactgctac tcatggtgct gcggcaggcc tctggccggc cccacggccc ccacggcctt
     1021 tttctgcgct acggagtgga ggcactaacc ctacgcggca tcaatagctt ccgccaatac
     1081 aagtatgatt tggcgacagt gggcaaggct ctggagggca tgttccgcaa gctcaaccac
     1141 ctcctggagc gcctgcacca gtcattcttc ttctacctgc tgccggccct ctcccgcttt
     1201 gtctccatcg gactctacat gcccgccacg ggcttcctgc tcctagtcct tggactcaag
     1261 gctctggagc tgtggatgca gttacaccag gctggagtca acccggagga ggctgggaag
     1321 gcccctagtc ccgggactcc actcttgcca acacagggtg tgggcctggc ctcacttacg
     1381 gcacccctgc tgatctctca ggccatgggt ctggccctct atttcctgcc tgtgctgggc
     1441 caacatttag ctactcagca tttcccagtg gccgaagccg aggctgttgt gttgacgctg
     1501 ctcgcgattt atgtagccgg cctggccctt ccacacaaca cccaccgagt ggtcaactca
     1561 caggtcccag acaggggctg gatggcactg aaactagtgg ccctcatcta cctggcactg
     1621 cagctgggtt gcattgctct cctcaatttc tccctgggct tcctgctggc tgccaccatg
     1681 gtccctgctg ctgcactcgc caagccccat gggccccgga cactgtatgc tgccctgctg
     1741 gtagtgacca gcccagcagt cacactcttc ggtagcctgt tcctgtggcg ggagctgctg
     1801 gaggtaccgc tgtctctggc agagggttgg cagctcttcc tcacagcatt ggcccagggt
     1861 gtgctggaac actacaccta tggcgccctc ctcttcccaa tactggcctt gggtctgtat
     1921 ccttgctggc tgcttttctg gaatgtcctc ttctggaagt gaggtgtctg ggaaggggtc
     1981 ccccaagcct ccgttctacc tcctccctgg gaaataaaca agtgctgtgt ttctgt
//
