LOCUS       NM_016810               4301 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus golgi SNAP receptor complex member 1 (Gosr1),
            transcript variant 1, mRNA.
ACCESSION   NM_016810
VERSION     NM_016810.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4301)
  AUTHORS   Kuliyev,E., Gingras,S., Guy,C.S., Howell,S., Vogel,P. and
            Pelletier,S.
  TITLE     Overlapping Role of SCYL1 and SCYL3 in Maintaining Motor Neuron
            Viability
  JOURNAL   J Neurosci 38 (10), 2615-2630 (2018)
   PUBMED   29437892
REFERENCE   2  (bases 1 to 4301)
  AUTHORS   Loh,E., Peter,F., Subramaniam,V.N. and Hong,W.
  TITLE     Mammalian Bet3 functions as a cytosolic factor participating in
            transport from the ER to the Golgi apparatus
  JOURNAL   J Cell Sci 118 (Pt 6), 1209-1222 (2005)
   PUBMED   15728249
REFERENCE   3  (bases 1 to 4301)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   4  (bases 1 to 4301)
  AUTHORS   Sagiv,Y., Legesse-Miller,A., Porat,A. and Elazar,Z.
  TITLE     GATE-16, a membrane transport modulator, interacts with NSF and the
            Golgi v-SNARE GOS-28
  JOURNAL   EMBO J 19 (7), 1494-1504 (2000)
   PUBMED   10747018
REFERENCE   5  (bases 1 to 4301)
  AUTHORS   Xu,Y., Wong,S.H., Tang,B.L., Subramaniam,V.N., Zhang,T. and Hong,W.
  TITLE     A 29-kilodalton Golgi soluble N-ethylmaleimide-sensitive factor
            attachment protein receptor (Vti1-rp2) implicated in protein
            trafficking in the secretory pathway
  JOURNAL   J Biol Chem 273 (34), 21783-21789 (1998)
   PUBMED   9705316
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK147799.1, AK133836.1, AK161386.1 and BQ032729.1.
            
            On Sep 29, 2017 this sequence version replaced NM_016810.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC008542.1, AK147799.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-14                AK147799.1         2-15
            15-894              AK133836.1         2-881
            895-986             AK161386.1         886-977
            987-3979            AK133836.1         974-3966
            3980-4282           AK133836.1         3968-4270
            4283-4301           BQ032729.1         1-19                c
FEATURES             Location/Qualifiers
     source          1..4301
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 46.02 cM"
     gene            1..4301
                     /gene="Gosr1"
                     /gene_synonym="GOS-28; GOSRI; GS28"
                     /note="golgi SNAP receptor complex member 1"
                     /db_xref="GeneID:53334"
                     /db_xref="MGI:MGI:1858260"
     exon            1..59
                     /gene="Gosr1"
                     /gene_synonym="GOS-28; GOSRI; GS28"
                     /inference="alignment:Splign:2.1.0"
     CDS             29..781
                     /gene="Gosr1"
                     /gene_synonym="GOS-28; GOSRI; GS28"
                     /note="isoform 1 is encoded by transcript variant 1;
                     Cis-Golgi SNARE; 28 kDa Golgi SNARE protein; 28 kDa
                     cis-Golgi SNARE p28"
                     /codon_start=1
                     /product="Golgi SNAP receptor complex member 1 isoform 1"
                     /protein_id="NP_058090.2"
                     /db_xref="CCDS:CCDS25070.1"
                     /db_xref="GeneID:53334"
                     /db_xref="MGI:MGI:1858260"
                     /translation="MAAGTSNYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSGSRD
                     GGRDRYSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAEYTHSAGVPSLNA
                     ALMHTLQRHRDILQDYTHEFHKTKANFTAIRERENLMGSVRKDIESYKSGSGVNNRRT
                     ELFLKEHDHLRNSDRLIEETISIAMATKENMTSQRGMLKSIHSKMNTLANRFPAVNSL
                     IQRINLRKRRDSLILGGVIGICTILLLLYAFH"
     exon            60..180
                     /gene="Gosr1"
                     /gene_synonym="GOS-28; GOSRI; GS28"
                     /inference="alignment:Splign:2.1.0"
     exon            181..268
                     /gene="Gosr1"
                     /gene_synonym="GOS-28; GOSRI; GS28"
                     /inference="alignment:Splign:2.1.0"
     exon            269..376
                     /gene="Gosr1"
                     /gene_synonym="GOS-28; GOSRI; GS28"
                     /inference="alignment:Splign:2.1.0"
     exon            377..468
                     /gene="Gosr1"
                     /gene_synonym="GOS-28; GOSRI; GS28"
                     /inference="alignment:Splign:2.1.0"
     exon            469..543
                     /gene="Gosr1"
                     /gene_synonym="GOS-28; GOSRI; GS28"
                     /inference="alignment:Splign:2.1.0"
     exon            544..573
                     /gene="Gosr1"
                     /gene_synonym="GOS-28; GOSRI; GS28"
                     /inference="alignment:Splign:2.1.0"
     exon            574..656
                     /gene="Gosr1"
                     /gene_synonym="GOS-28; GOSRI; GS28"
                     /inference="alignment:Splign:2.1.0"
     exon            657..4288
                     /gene="Gosr1"
                     /gene_synonym="GOS-28; GOSRI; GS28"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4268..4273
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gosr1"
                     /gene_synonym="GOS-28; GOSRI; GS28"
                     /note="hexamer: AATAAA"
     polyA_site      4288
                     /gene="Gosr1"
                     /gene_synonym="GOS-28; GOSRI; GS28"
                     /note="major polyA site"
ORIGIN      
        1 ctgtcccgac tgacgttggg caacaaagat ggcggcagga accagcaatt actgggaaga
       61 tctcaggaaa caagctcggc agctggaaaa cgaacttgac ctgaaactcg tttccttcag
      121 taaactctgt acgagctaca gccacagcgg ctcacgggat ggaggacgcg ataggtacag
      181 ttctgacaca acaccgctat taaatggatc aagccaagac agaatgtttg agacaatggc
      241 aattgaaatt gaacagcttt tggcaaggct tacaggagta aacgacaaaa tggcagagta
      301 cacccacagt gcaggggtgc cctccctgaa tgcagccctg atgcacacgc tgcagcgaca
      361 cagagacatt ctgcaggatt atacacacga atttcataaa accaaagcaa actttacggc
      421 aatacgggaa agggagaatc tcatgggatc agtacggaaa gatattgagt catataaaag
      481 cgggtctgga gtaaacaaca ggagaacgga actgtttctg aaagagcatg accaccttcg
      541 aaactctgat cgtctgatag aagaaacaat aagcattgct atggcaacaa aagagaatat
      601 gacttcccag agaggaatgc tcaagtcaat tcacagcaag atgaacactc tggccaaccg
      661 ctttcctgcc gtgaacagcc tgatacaaag gatcaacctt aggaaacggc gtgactcgct
      721 catccttgga ggtgtcattg gcatctgcac catcctgttg ctgctgtatg cgttccactg
      781 aaagcatagc cccaggactc tctgcccacc accttcatgg cctgatctgg actggggagc
      841 ctaccaagga gaaagaccat cccggccacg ggcgccagca gatggattcc aaactgcacc
      901 tgtggctctg acctggtcgg gctgagctga agccgaagtt tttctgtgct atcttttcta
      961 atacacatta ctctgttttt aattttaaaa acaacaaaag gtttccgttg ctgtgtctcc
     1021 ctaggaggta agcaggcaga agctgagaag ctgggcttca gtgactggcg aggccagatg
     1081 atcagcgggc ctcggagctg gactcctcgt agcaccagac tctctacatc caaagatggc
     1141 ttcactttca gccacgagat tggatgtgaa taaaagtaat ttttgtcctt ttatttaaca
     1201 cttgtgatga gtaatcagct gtcctttgct gatactctgt gatctgtatt ctattctgtg
     1261 tccctaactc ttagcagtca agaaaaattc catgtcccac gggttctgtg agatgttggt
     1321 aggccagctt catgtttgag gtggtctgaa atggagagtg ctgtagaaag ggcgtctcgt
     1381 ctctgcgtca gctgtgagcg ctgcgtcagc tgtaccgccg ccaacacatc agaatggcag
     1441 accttgccat tgctttatta ttttttccac tgggctaata tttgcttgta catgataaaa
     1501 ttgcatttcc actgacaggc aatcagcacc tgtcattgcc cctagcggtc ccatatcatg
     1561 tgaagcttaa tactaggaag tgagggaggg gacttggttc tcagtgaggt ctgctcatga
     1621 gccactgcaa ggagacagtg agagggtggc tctctggcct tcctgtctgt cagtgtggtg
     1681 ccgcctggag caagggtagc actgtgacct gatgtcacag tattcgtgcc ctgtgcagat
     1741 ctatcccttc ctcctctgtt ggcgccttcc ttcctactcc taggccgccg gataaccact
     1801 gagggggcct gggactcctg cctgcacctc tctattactt tgggcagtga cagaattgtg
     1861 aatgtttctc aaggttagcc acttctcagc atctgtaaat tggtaacttg tcgtactgaa
     1921 ctagcggata gtgtaaagac tccaacatct gtgctctgct ggtcctaccc tggagtggcc
     1981 tccagcacat tgtccagggg cagtgagtgg atattagagc tcttcaccat tctatggtgg
     2041 gggacggtgc ctctgggcca ccttgataca cttactgcgc atggacagac tgacacccag
     2101 tctgggactg actgacagtt ttgacatcct gctgttgaag tgttagtaca ttctaggtat
     2161 gaaaggcatt tgatatattt ttcttaatta tggggtttat ttttctaaat atgggttaat
     2221 cagcttgttg actgggcatg cccttaaaag gaatttaaat ttccctctat agaccttaaa
     2281 gaatcaggga agttcatttg ttaaattctc cttgagagaa cagaacttct cttccctgac
     2341 acttctatta tctttgattt tttcaaaggg ccttgattgg catttgtgcc tcagctagac
     2401 tttatgggac tttggttgtt atatagtggg catatatgaa atctgaagta tcgtaaataa
     2461 agttatttat ttaaatatac agccagtctt ttctactggt ttgatgacat gtttcattca
     2521 ctaaagctga tgagaaagcg taggctagga catggtcctg ctccactgcc agccgccacc
     2581 gcacagcagc tgggccgccc caggacgctg cactcagatg aacagatgga attatgttgc
     2641 ttgtcttctt tttgagagta gatcagttct ttcaaggaac gctagctgta gcggctgggg
     2701 tccgaccttc cattgtggtg ccgtggaggg aagagtgccc ctccctttcc agttctgccc
     2761 tgtacaggac ccccttggaa cctcggtttt gtgtcattca atattttttt caagttcgtt
     2821 tctcccattt tgggcttacc ccagttatca ggcttaggca tggacaggga gggatgtctt
     2881 gtcagagcct gaggtaagat ttgtgacccc agtgaactgt tgctccccgg ccacagtttt
     2941 taacagaata ccttttttta aaaatatata tttttagtaa cagttcaaaa cttcccactt
     3001 cacaaaaaga tatgaaaaac gggaataaac agcagaaaat tccaagtgta tttgtctgcc
     3061 ctggcttgag aggtctcact gtttagctcc ggctggcctt gagttcctgc ctcggcttcc
     3121 tgagaccctg ggactactat ctgatgtata ccaccaaccc tggctccaaa cagtaccttc
     3181 ctccagtttc ccatgtgtcc cagtgactca gtgaagatgt gcagtccatt gctactgaga
     3241 tctacaaacc cataccaaag gatgctctgc ctcctgccct gctcacctct gcttgttccc
     3301 ttccccttga taccagcatt gacatttatt gagaatgtct ttctgcttct tcctggtact
     3361 cggatcagaa atggggacag gtgaggaaga gccactctag aggacacttt tgtactggga
     3421 cccagatagc tgagggcctc catgctggtc gtggataagt gagtgggaag cacagtcatt
     3481 gctctgccgc cctgtgagcc ctgtggagtt gaggcacctt ggccttcacc acatcactgt
     3541 cctgtcttac tgctgatgac ctcggcctga gggggtggct tctaagaatg ggtctagcct
     3601 ttccgacttc tctttatctt ctgtctttaa ccaggtaaga gttttgggat tcattgagct
     3661 tttgaacttg ttatattaag tggttgggat gcatggccat acccaggtca tctgtggcag
     3721 atgcggcaga ggaaacaaac ctacccaaat gacggattgt gcactgtcct tattttaccg
     3781 tagagggcat cctttggcct gatctccaaa aggatgcagc atttcccact gcgggcccca
     3841 aactcattca tccccctgag tgcccatatg tccctttctc agagagaatg ggggacgaga
     3901 aacaaggtct taacgtgata atctggtgag aagctgggaa agttgagtca tgtcttaaag
     3961 aatgtgtttt tttttttttc aatctgatct aaaatcttag taccaaaata tttgtaccac
     4021 accctagtag ctctcagtga tgggaaatca gttcttacca tactttattc cgatggaaga
     4081 cgattgacgc ctggtgaaaa atgccaatac agattttttt taatctattc ttttccaaat
     4141 gcactttcta attttttgct tttaaaatag agacttggaa ccaatattat tgtattttta
     4201 cttaattttt gttctcatct aaatgtgcat tttctgactg tatagaagaa actttgttat
     4261 ataatttaat aaattaaata tctaaataaa aaaaaaaaaa a
//
