LOCUS       NM_028976               3483 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus golgi reassembly stacking protein 1 (Gorasp1), mRNA.
ACCESSION   NM_028976
VERSION     NM_028976.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3483)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3483)
  AUTHORS   Guo,D., Ru,J., Mao,F., Ouyang,H., Ju,R., Wu,K., Liu,Y. and Liu,C.
  TITLE     Ontogenesis of the tear drainage system requires Prickle1-driven
            polarized basement membrane deposition
  JOURNAL   Development 147 (22) (2020)
   PUBMED   33144400
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3483)
  AUTHORS   Grond,R., Veenendaal,T., Duran,J.M., Raote,I., van Es,J.H.,
            Corstjens,S., Delfgou,L., El Haddouti,B., Malhotra,V. and
            Rabouille,C.
  TITLE     The function of GORASPs in Golgi apparatus organization in vivo
  JOURNAL   J Cell Biol 219 (9) (2020)
   PUBMED   32573693
  REMARK    GeneRIF: The function of GORASPs in Golgi apparatus organization in
            vivo.
            Erratum:[J Cell Biol. 2020 Sep 7;219(9):jcb.20200419106242020c.
            doi: 10.1083/jcb.20200419106242020c.. PMID: 32589188]
REFERENCE   4  (bases 1 to 3483)
  AUTHORS   Man,J.C.K., Mohan,R.A., Boogaard,M.V.D., Hilvering,C.R.E.,
            Jenkins,C., Wakker,V., Bianchi,V., Laat,W., Barnett,P.,
            Boukens,B.J. and Christoffels,V.M.
  TITLE     An enhancer cluster controls gene activity and topology of the
            SCN5A-SCN10A locus in vivo
  JOURNAL   Nat Commun 10 (1), 4943 (2019)
   PUBMED   31666509
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3483)
  AUTHORS   Xie,Z., Hur,S.K., Zhao,L., Abrams,C.S. and Bankaitis,V.A.
  TITLE     A Golgi Lipid Signaling Pathway Controls Apical Golgi Distribution
            and Cell Polarity during Neurogenesis
  JOURNAL   Dev Cell 44 (6), 725-740 (2018)
   PUBMED   29587143
REFERENCE   6  (bases 1 to 3483)
  AUTHORS   Veenendaal,T., Jarvela,T., Grieve,A.G., van Es,J.H., Linstedt,A.D.
            and Rabouille,C.
  TITLE     GRASP65 controls the cis Golgi integrity in vivo
  JOURNAL   Biol Open 3 (6), 431-443 (2014)
   PUBMED   24795147
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 3483)
  AUTHORS   Huang,W., She,L., Chang,X.Y., Yang,R.R., Wang,L., Ji,H.B.,
            Jiao,J.W. and Poo,M.M.
  TITLE     Protein kinase LKB1 regulates polarized dendrite formation of adult
            hippocampal newborn neurons
  JOURNAL   Proc Natl Acad Sci U S A 111 (1), 469-474 (2014)
   PUBMED   24367100
REFERENCE   8  (bases 1 to 3483)
  AUTHORS   Tamaki,H., Sanda,M., Katsumata,O., Hara,Y., Fukaya,M. and
            Sakagami,H.
  TITLE     Pilt is a coiled-coil domain-containing protein that localizes at
            the trans-Golgi complex and regulates its structure
  JOURNAL   FEBS Lett 586 (19), 3064-3070 (2012)
   PUBMED   22841714
REFERENCE   9  (bases 1 to 3483)
  AUTHORS   Matsuki,T., Matthews,R.T., Cooper,J.A., van der Brug,M.P.,
            Cookson,M.R., Hardy,J.A., Olson,E.C. and Howell,B.W.
  TITLE     Reelin and stk25 have opposing roles in neuronal polarization and
            dendritic Golgi deployment
  JOURNAL   Cell 143 (5), 826-836 (2010)
   PUBMED   21111240
REFERENCE   10 (bases 1 to 3483)
  AUTHORS   Kelkar,N., Standen,C.L. and Davis,R.J.
  TITLE     Role of the JIP4 scaffold protein in the regulation of
            mitogen-activated protein kinase signaling pathways
  JOURNAL   Mol Cell Biol 25 (7), 2733-2743 (2005)
   PUBMED   15767678
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC124662.10.
            
            On Nov 17, 2006 this sequence version replaced NM_028976.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC012251.1, AK154986.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134, SAMN01164143
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-101               AC124662.10        43058-43158
            102-182             AC124662.10        47274-47354
            183-386             AC124662.10        47792-47995
            387-473             AC124662.10        50310-50396
            474-604             AC124662.10        50513-50643
            605-815             AC124662.10        50855-51065
            816-966             AC124662.10        51653-51803
            967-1119            AC124662.10        52237-52389
            1120-3483           AC124662.10        52580-54943
FEATURES             Location/Qualifiers
     source          1..3483
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 71.33 cM"
     gene            1..3483
                     /gene="Gorasp1"
                     /gene_synonym="5430411C10Rik; GOLPH5; GRASP65; P65"
                     /note="golgi reassembly stacking protein 1"
                     /db_xref="GeneID:74498"
                     /db_xref="MGI:MGI:1921748"
     exon            1..101
                     /gene="Gorasp1"
                     /gene_synonym="5430411C10Rik; GOLPH5; GRASP65; P65"
                     /inference="alignment:Splign:2.1.0"
     CDS             42..1382
                     /gene="Gorasp1"
                     /gene_synonym="5430411C10Rik; GOLPH5; GRASP65; P65"
                     /note="golgi peripheral membrane protein p65; golgi
                     reassembly-stacking protein of 65 kDa"
                     /codon_start=1
                     /product="Golgi reassembly-stacking protein 1"
                     /protein_id="NP_083252.1"
                     /db_xref="CCDS:CCDS23619.1"
                     /db_xref="GeneID:74498"
                     /db_xref="MGI:MGI:1921748"
                     /translation="MGLGASSEQPAGGEGFHLHGVQENSPAQQAGLEPYFDFIITIGH
                     SRLNKENDTLKALLKANVEKPVKLEVFNMKTMKVREVEVVPSNMWGGQGLLGASVRFC
                     SFRRASEHVWHVLDVEPSSPAALAGLCPYTDYIVGSDQILQESEDFFTLIESHEGKPL
                     KLMVYNSESDSCREVTVTPNAAWGGEGSLGCGIGYGYLHRIPTQPSSQHKKPPGATPP
                     GTPATTSQLTAFPLGAPPPWPIPQDSSGPELGSRQSDFMEALPQVPGSFMEGQLLGPG
                     SPSHGAADCGGCLRAMEIPLQPPPPVQRVMDPGFLDVSGMSLLDSSNISVCPSLSSST
                     VLTSTAVSVSGPEDIGSSSSSHERGGEATWSGSEFEISFPDSPGAQAQADHLPRLTLP
                     DGLTSAASPEEGLSAELLEAQTEEPADTASLDCRAETEGRASQAQATPDPEPGL"
     exon            102..182
                     /gene="Gorasp1"
                     /gene_synonym="5430411C10Rik; GOLPH5; GRASP65; P65"
                     /inference="alignment:Splign:2.1.0"
     exon            183..386
                     /gene="Gorasp1"
                     /gene_synonym="5430411C10Rik; GOLPH5; GRASP65; P65"
                     /inference="alignment:Splign:2.1.0"
     exon            387..473
                     /gene="Gorasp1"
                     /gene_synonym="5430411C10Rik; GOLPH5; GRASP65; P65"
                     /inference="alignment:Splign:2.1.0"
     exon            474..604
                     /gene="Gorasp1"
                     /gene_synonym="5430411C10Rik; GOLPH5; GRASP65; P65"
                     /inference="alignment:Splign:2.1.0"
     exon            605..815
                     /gene="Gorasp1"
                     /gene_synonym="5430411C10Rik; GOLPH5; GRASP65; P65"
                     /inference="alignment:Splign:2.1.0"
     exon            816..966
                     /gene="Gorasp1"
                     /gene_synonym="5430411C10Rik; GOLPH5; GRASP65; P65"
                     /inference="alignment:Splign:2.1.0"
     exon            967..1119
                     /gene="Gorasp1"
                     /gene_synonym="5430411C10Rik; GOLPH5; GRASP65; P65"
                     /inference="alignment:Splign:2.1.0"
     exon            1120..3483
                     /gene="Gorasp1"
                     /gene_synonym="5430411C10Rik; GOLPH5; GRASP65; P65"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2545..2550
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gorasp1"
                     /gene_synonym="5430411C10Rik; GOLPH5; GRASP65; P65"
                     /note="hexamer: AATAAA"
     polyA_site      2568
                     /gene="Gorasp1"
                     /gene_synonym="5430411C10Rik; GOLPH5; GRASP65; P65"
                     /note="major polyA site"
     regulatory      3467..3472
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gorasp1"
                     /gene_synonym="5430411C10Rik; GOLPH5; GRASP65; P65"
                     /note="hexamer: TATAAA"
     polyA_site      3483
                     /gene="Gorasp1"
                     /gene_synonym="5430411C10Rik; GOLPH5; GRASP65; P65"
                     /note="major polyA site"
ORIGIN      
        1 ccccacgtga ctaggccacg cagcagcggg agagggcggc catggggcta ggggcaagca
       61 gcgagcagcc ggcgggcggc gagggcttcc atctgcacgg ggtacaagag aactcgccgg
      121 cccagcaggc aggcctggag ccctacttcg acttcatcat caccatcggg cactcgaggc
      181 tgaacaagga gaacgacacg ctgaaggcat tgctgaaggc caatgtggag aagccggtga
      241 agctggaggt attcaacatg aagaccatga aggtgcgcga ggtagaggtg gtgcccagca
      301 acatgtgggg cggccagggc ctcctgggag ccagcgtgcg cttctgtagc ttccgcaggg
      361 ccagcgaaca cgtgtggcat gtgctggatg tggagccctc ttcacctgct gccttggccg
      421 gcctgtgccc ttacacagac tacatagttg gctctgacca gattctccag gagtcagaag
      481 acttctttac tctcattgag tcccatgagg ggaagcctct gaagctgatg gtgtataact
      541 cggagtccga ctcctgccgg gaggtgactg tgactcccaa tgcagcctgg ggtggagagg
      601 gcagtctggg gtgtggtatt ggttatgggt acctgcatcg gatcccaacg caaccctcca
      661 gccagcacaa gaagccaccc ggtgccacac cacctggcac tccagctacg acctcacaac
      721 ttactgcctt tcctcttggt gccccaccac cttggcctat ccctcaggac tcttctggcc
      781 cagagttggg ttccaggcag agtgacttca tggaggccct accacaagtc cctggtagct
      841 ttatggaggg acagctcctt gggcctggga gtcccagcca tggcgctgct gactgtgggg
      901 gatgcctgcg tgctatggag atcccgcttc agcctccacc tccagtgcag cgggtcatgg
      961 acccaggctt cctggatgta tcaggcatgt ccctcctgga cagcagcaac ataagcgtgt
     1021 gccccagcct gtcatcttcc acagtgctga cctccacagc tgtttcagtc tcaggaccag
     1081 aggacattgg ttctagcagc agttctcacg agcggggtgg tgaagccacg tggtcagggt
     1141 cagagtttga gatctccttc ccagacagtc caggtgccca ggcccaggcg gaccacctgc
     1201 cccggctgac tctccccgat ggcctcacat ctgcggcctc acctgaagaa gggctgtctg
     1261 cagagctgct ggaagcacag actgaggagc cggcagacac agccagcctg gattgcaggg
     1321 cagagactga ggggagagcc agccaagcgc aggccacccc agatccagag cctgggctgt
     1381 gagaacaccc ctggtgacat ttggtgtggc ttagctgggt agctctctag gctgcaggct
     1441 cttgtgaggc acgggcattg ctacaataca tacatggtcc tgggtcgaag ggacagcaca
     1501 cccgagcagc aaccagcttc tgtagaggca ggtgacggaa tctagactgt caatgaagca
     1561 tcgatgcccc atcacaatat ccaggtgaag atggggcgag ggacaagagg ctgtgtccat
     1621 aggcagccac acctgtactg aggaagaccc taagtcccaa tgcccttcct cactctaatc
     1681 cttacactgg atgagcgagg tggtatatct ggccacttta tttcttagga tgggaaattc
     1741 tagggattta ccttcagagg gatctacctc cgctagctgt tcacagcccc agggggaggt
     1801 acaaaggagc ttacactcca gttcttgggt cctatgacgc tcccttcagc cctcacgtag
     1861 acagctggct ctggtggcag acgggtcaaa ctacgcttcc tgtcaaaacc cctccacctg
     1921 cccgtgctca gggttcttct cctgaagagc tggaaaaggc ccctcccacc tgtcctcagc
     1981 gtaagggaaa ggagccttta caggctcagt ctccgagagg acagctgcac cgctgccttg
     2041 ctacagatgg tgccaggcat gtcctctgca gccccagttc catgtccttt gccaatcact
     2101 gtaagctgcc tttggtcttc ttttccagcc tctttgttcc atcatccaca gaccatgtaa
     2161 ctgtctgttc agggtactta ggctggtaag ccaaggactc tgttccaaga agcacaggcc
     2221 aaatggttca gtgggccagg tcctggatgg gcaaacagaa cccaaagcac taggaataca
     2281 tttatagcca ggcctgtgag gcccccgctc cccaggggcc actgagaggc ctgaggccgt
     2341 acaacatggc ttaccacagg gctgctctgg ggccagctca atttagctgt ggttaggcac
     2401 tctgaccccc agctgccttc attggaaggt tctgctcccc aggaccccat gtggggtgaa
     2461 acggaggctg atgctgtttc aagtatgaac ccccagatgg tttctttccc tgtaatctgc
     2521 tatggggaaa gtgacaagtg aaaaaataaa catgtccagc acactgaagt gtttgtaact
     2581 aaagctttat tctatacaac ccgagataca gactctgccc ctttggcgtt gcagactgtc
     2641 cagttttctg gaaacttagt actgattttt gactagctgg ggaaaaaatt acaaccatgc
     2701 tggggtaaac tcctccatag gggcacaact gcctgtggat cagtactgcg ccagtgaacc
     2761 aaccagcaaa ccctacgctt agtgcagagg cccctcctgc aaacacgacc accccacccc
     2821 ctgcttttac tttatagcta tcactaaaaa atatgcacca aaagtgcacc gatgtgtcca
     2881 gcatagaaag gacttctgta gaaaagctgg ctactctagg gcggagaatg gtttaacact
     2941 ggcaagtgtt cttgctcact tgagggtatg gaagccatgg cctgtctgtg ttccagagtt
     3001 aagtgagggg accctgttct gcagtcaatt tgtaagggac agatctgggc ccctcagctg
     3061 ttccctgcag gacctgtgag atagagagaa aacatctttc ttccccaagc ccccctcccc
     3121 tgtgctcctg tgggcaggga ccacacacac aaggcaggag cagacggacg gatggggaaa
     3181 gctgcacccc ccacccccaa ggcacgtgtg cttccgctgt gctcaaaggt tcatctcctg
     3241 cagcttcacg ggctggacca tttgtctgaa tgtaaatgac cttgggaaga atccaaagta
     3301 gtttttgcca aaagttgaag tgtttatccc caataagtta atattctgta caagatccaa
     3361 gtgagtctat gaaagctttt gactgttaga aagacggcag aaagacctgg acgaaggcgt
     3421 aacaaaagcc cgtgtataaa actggaaaaa caaacatgaa ccacaatata aatatcaaac
     3481 caa
//
