LOCUS       NP_084069                758 aa            linear   ROD 05-JUN-2024
DEFINITION  golgin subfamily A member 1 isoform a [Mus musculus].
ACCESSION   NP_084069
VERSION     NP_084069.1
DBSOURCE    REFSEQ: accession NM_029793.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 758)
  AUTHORS   Iwaki,A., Moriwaki,K., Sobajima,T., Taniguchi,M., Yoshimura,S.I.,
            Kunii,M., Kanda,S., Kamada,Y., Miyoshi,E. and Harada,A.
  TITLE     Loss of Rab6a in the small intestine causes lipid accumulation and
            epithelial cell death from lactation
  JOURNAL   FASEB J 34 (7), 9450-9465 (2020)
   PUBMED   32496646
REFERENCE   2  (residues 1 to 758)
  AUTHORS   Farini,D., Cesari,E., Weatheritt,R.J., La Sala,G., Naro,C.,
            Pagliarini,V., Bonvissuto,D., Medici,V., Guerra,M., Di Pietro,C.,
            Rizzo,F.R., Musella,A., Carola,V., Centonze,D., Blencowe,B.J.,
            Marazziti,D. and Sette,C.
  TITLE     A Dynamic Splicing Program Ensures Proper Synaptic Connections in
            the Developing Cerebellum
  JOURNAL   Cell Rep 31 (9), 107703 (2020)
   PUBMED   32492419
REFERENCE   3  (residues 1 to 758)
  AUTHORS   Xie,Z., Hur,S.K., Zhao,L., Abrams,C.S. and Bankaitis,V.A.
  TITLE     A Golgi Lipid Signaling Pathway Controls Apical Golgi Distribution
            and Cell Polarity during Neurogenesis
  JOURNAL   Dev Cell 44 (6), 725-740 (2018)
   PUBMED   29587143
REFERENCE   4  (residues 1 to 758)
  AUTHORS   Banushi,B., Forneris,F., Straatman-Iwanowska,A., Strange,A.,
            Lyne,A.M., Rogerson,C., Burden,J.J., Heywood,W.E., Hanley,J.,
            Doykov,I., Straatman,K.R., Smith,H., Bem,D., Kriston-Vizi,J.,
            Ariceta,G., Risteli,M., Wang,C., Ardill,R.E., Zaniew,M.,
            Latka-Grot,J., Waddington,S.N., Howe,S.J., Ferraro,F., Gjinovci,A.,
            Lawrence,S., Marsh,M., Girolami,M., Bozec,L., Mills,K. and
            Gissen,P.
  TITLE     Regulation of post-Golgi LH3 trafficking is essential for collagen
            homeostasis
  JOURNAL   Nat Commun 7, 12111 (2016)
   PUBMED   27435297
  REMARK    Publication Status: Online-Only
REFERENCE   5  (residues 1 to 758)
  AUTHORS   Fairfield,H., Srivastava,A., Ananda,G., Liu,R., Kircher,M.,
            Lakshminarayana,A., Harris,B.S., Karst,S.Y., Dionne,L.A.,
            Kane,C.C., Curtain,M., Berry,M.L., Ward-Bailey,P.F., Greenstein,I.,
            Byers,C., Czechanski,A., Sharp,J., Palmer,K., Gudis,P., Martin,W.,
            Tadenev,A., Bogdanik,L., Pratt,C.H., Chang,B., Schroeder,D.G.,
            Cox,G.A., Cliften,P., Milbrandt,J., Murray,S., Burgess,R.,
            Bergstrom,D.E., Donahue,L.R., Hamamy,H., Masri,A., Santoni,F.A.,
            Makrythanasis,P., Antonarakis,S.E., Shendure,J. and Reinholdt,L.G.
  TITLE     Exome sequencing reveals pathogenic mutations in 91 strains of mice
            with Mendelian disorders
  JOURNAL   Genome Res 25 (7), 948-957 (2015)
   PUBMED   25917818
REFERENCE   6  (residues 1 to 758)
  AUTHORS   Yang,T., Mendoza-Londono,R., Lu,H., Tao,J., Li,K., Keller,B.,
            Jiang,M.M., Shah,R., Chen,Y., Bertin,T.K., Engin,F., Dabovic,B.,
            Rifkin,D.B., Hicks,J., Jamrich,M., Beaudet,A.L. and Lee,B.
  TITLE     E-selectin ligand-1 regulates growth plate homeostasis in mice by
            inhibiting the intracellular processing and secretion of mature
            TGF-beta
  JOURNAL   J Clin Invest 120 (7), 2474-2485 (2010)
   PUBMED   20530870
REFERENCE   7  (residues 1 to 758)
  AUTHORS   Pooley,R.D., Moynihan,K.L., Soukoulis,V., Reddy,S., Francis,R.,
            Lo,C., Ma,L.J. and Bader,D.M.
  TITLE     Murine CENPF interacts with syntaxin 4 in the regulation of
            vesicular transport
  JOURNAL   J Cell Sci 121 (Pt 20), 3413-3421 (2008)
   PUBMED   18827011
REFERENCE   8  (residues 1 to 758)
  AUTHORS   Feng,L., Xie,X., Ding,Q., Luo,X., He,J., Fan,F., Liu,W., Wang,Z.
            and Chen,Y.
  TITLE     Spatial regulation of Raf kinase signaling by RKTG
  JOURNAL   Proc Natl Acad Sci U S A 104 (36), 14348-14353 (2007)
   PUBMED   17724343
REFERENCE   9  (residues 1 to 758)
  AUTHORS   Nichols,R.J. and Traktman,P.
  TITLE     Characterization of three paralogous members of the Mammalian
            vaccinia related kinase family
  JOURNAL   J Biol Chem 279 (9), 7934-7946 (2004)
   PUBMED   14645249
REFERENCE   10 (residues 1 to 758)
  AUTHORS   Ramalho-Santos,J., Moreno,R.D., Wessel,G.M., Chan,E.K. and
            Schatten,G.
  TITLE     Membrane trafficking machinery components associated with the
            mammalian acrosome during spermiogenesis
  JOURNAL   Exp Cell Res 267 (1), 45-60 (2001)
   PUBMED   11412037
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL844588.17, BY084848.1, BC043090.1 and AK163007.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longer isoform (a).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC043090.1, SRR7652917.126018.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..758
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 24.42 cM"
     Protein         1..758
                     /product="golgin subfamily A member 1 isoform a"
                     /note="golgin subfamily A member 1; golgi autoantigen,
                     golgin subfamily a, 1"
                     /calculated_mol_wt=87207
     Region          13..58
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9CW79.2)"
     Site            30
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:17242355,
                     ECO:0007744|PubMed:21183079; propagated from
                     UniProtKB/Swiss-Prot (Q9CW79.2)"
     Site            36
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:17242355,
                     ECO:0007744|PubMed:21183079; propagated from
                     UniProtKB/Swiss-Prot (Q9CW79.2)"
     Site            41
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:17242355,
                     ECO:0007744|PubMed:21183079; propagated from
                     UniProtKB/Swiss-Prot (Q9CW79.2)"
     Site            47
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:21183079; propagated from
                     UniProtKB/Swiss-Prot (Q9CW79.2)"
     Site            50
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q92805; propagated from
                     UniProtKB/Swiss-Prot (Q9CW79.2)"
     Site            51
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q92805; propagated from
                     UniProtKB/Swiss-Prot (Q9CW79.2)"
     Region          <53..>621
                     /region_name="Smc"
                     /note="Chromosome segregation ATPase Smc [Cell cycle
                     control, cell division, chromosome partitioning]; COG1196"
                     /db_xref="CDD:440809"
     Region          683..728
                     /region_name="Grip"
                     /note="golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
                     smart00755"
                     /db_xref="CDD:197860"
     Region          739..758
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9CW79.2)"
     CDS             1..758
                     /gene="Golga1"
                     /gene_synonym="0710001G09Rik; 2210418B03Rik; awag;
                     Golgi97; golgin-97"
                     /coded_by="NM_029793.2:339..2615"
                     /note="isoform a is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS16016.1"
                     /db_xref="GeneID:76899"
                     /db_xref="MGI:MGI:1924149"
ORIGIN      
        1 mfaklkkkia eetavaqrpg gttriprsvs kesvasmgad sgddfasdgs ssredlssql
       61 lrrneqirkl earlsdyaeq vrnlqkikek leialekhqd ssmrkfqeqn etfqasrakm
      121 aeglalalar kdqewsekme qlekdkrflt sqlqevknqs lslfqkrdei delegfqqqe
      181 iskvkhmllk keeclgkmeq eldartreln rtqeelvtsn qlssdlnerl eelqrhcstl
      241 eeqrdhltas kagaehkivv leqkeqelqa iiqqhsidlq kvtaetqeke kvithlqekv
      301 iflekrleqn lsgedhvqel lkektvaeqn ledtrqqlla arnshtkaly lletrvkdle
      361 rslqaaeeql sqsrnvvadq eaqiqklitt nqenslsqqq vlaleqhcre rihaleaqie
      421 aleqtrvadq iaseqgmlql qqenvalkes rnecehslqh hqlelkklkd ewsqreivsv
      481 amaqaleevr kqreefqqqa teltaiieek nqslcekdea llqkeqelrq lekghssall
      541 qmhklqrele alktckaqea mpattgedcl plqgqeplvi skamqnseye lpaaegtpng
      601 evgasdlkql qkekqdleqq lieknkimkq mqqrmlelkk tlqkelkirp dselfevrek
      661 tgpeipnmap svtnntdltd areinfeylk hvvlkfmscr eseafhlika vsvllnfsqe
      721 eenmlketle ykmswfgskp tpkgsirpsi snpripws
//
