LOCUS       NM_011937               2300 bp    mRNA    linear   ROD 16-FEB-2025
DEFINITION  Mus musculus glucosamine-6-phosphate deaminase 1 (Gnpda1), mRNA.
ACCESSION   NM_011937
VERSION     NM_011937.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2300)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2300)
  AUTHORS   Mohammed,Y., Michaud,S.A., Petrosova,H., Yang,J., Ganguly,M.,
            Schibli,D., Flenniken,A.M., Nutter,L.M.J., Adissu,H.A.,
            Lloyd,K.C.K., McKerlie,C. and Borchers,C.H.
  TITLE     Proteotyping of knockout mouse strains reveals sex- and
            strain-specific signatures in blood plasma
  JOURNAL   NPJ Syst Biol Appl 7 (1), 25 (2021)
   PUBMED   34050187
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2300)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   4  (bases 1 to 2300)
  AUTHORS   Sakakura,Y., Shibui,T., Irie,K. and Yajima,T.
  TITLE     Metabolic mode peculiar to Meckel's cartilage: immunohistochemical
            comparisons of hypoxia-inducible factor-1alpha and glucose
            transporters in developing endochondral bones in mice
  JOURNAL   Eur J Oral Sci 116 (4), 341-352 (2008)
   PUBMED   18705802
REFERENCE   5  (bases 1 to 2300)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
REFERENCE   6  (bases 1 to 2300)
  AUTHORS   Arreola,R., Valderrama,B., Morante,M.L. and Horjales,E.
  TITLE     Two mammalian glucosamine-6-phosphate deaminases: a structural and
            genetic study
  JOURNAL   FEBS Lett 551 (1-3), 63-70 (2003)
   PUBMED   12965206
REFERENCE   7  (bases 1 to 2300)
  AUTHORS   Neidhardt,L., Gasca,S., Wertz,K., Obermayr,F., Worpenberg,S.,
            Lehrach,H. and Herrmann,B.G.
  TITLE     Large-scale screen for genes controlling mammalian embryogenesis,
            using high-throughput gene expression analysis in mouse embryos
  JOURNAL   Mech Dev 98 (1-2), 77-94 (2000)
   PUBMED   11044609
REFERENCE   8  (bases 1 to 2300)
  AUTHORS   Nakamura,Y., Miura,K., Fujino,Y., Iwao,H., Ogita,S. and Yamanaka,S.
  TITLE     Evolution, structure, and expression of GNPI/Oscillin orthologous
            genes
  JOURNAL   Genomics 68 (2), 179-186 (2000)
   PUBMED   10964516
REFERENCE   9  (bases 1 to 2300)
  AUTHORS   Amireault,P. and Dube,F.
  TITLE     Cloning, sequencing, and expression analysis of mouse
            glucosamine-6-phosphate deaminase (GNPDA/oscillin)
  JOURNAL   Mol Reprod Dev 56 (3), 424-435 (2000)
   PUBMED   10862010
REFERENCE   10 (bases 1 to 2300)
  AUTHORS   Montag,M., van der Ven,K., Dorbecker,C. and van der Ven,H.
  TITLE     Characterization of testicular mouse glucosamine 6-phosphate
            deaminase (GNPDA)
  JOURNAL   FEBS Lett 458 (2), 141-144 (1999)
   PUBMED   10481053
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ048539.1, BY092839.1, AK167088.1 and BY443103.1.
            
            On May 15, 2008 this sequence version replaced NM_011937.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK166069.1, AK080610.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-26                CJ048539.1         2-27
            27-404              BY092839.1         2-379
            405-2276            AK167088.1         79-1950
            2277-2300           BY443103.1         413-436
FEATURES             Location/Qualifiers
     source          1..2300
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 20.23 cM"
     gene            1..2300
                     /gene="Gnpda1"
                     /gene_synonym="Gnp1; GNPDA; Gnpi; oscillin"
                     /note="glucosamine-6-phosphate deaminase 1"
                     /db_xref="GeneID:26384"
                     /db_xref="MGI:MGI:1347054"
     exon            1..86
                     /gene="Gnpda1"
                     /gene_synonym="Gnp1; GNPDA; Gnpi; oscillin"
                     /inference="alignment:Splign:2.1.0"
     exon            87..218
                     /gene="Gnpda1"
                     /gene_synonym="Gnp1; GNPDA; Gnpi; oscillin"
                     /inference="alignment:Splign:2.1.0"
     CDS             95..964
                     /gene="Gnpda1"
                     /gene_synonym="Gnp1; GNPDA; Gnpi; oscillin"
                     /EC_number="3.5.99.6"
                     /note="glucosamine-6-phosphate isomerase 1; GNPDA 1;
                     glcN6P deaminase 1; glucose-6-phosphate isomerase; protein
                     oscillin"
                     /codon_start=1
                     /product="glucosamine-6-phosphate deaminase 1"
                     /protein_id="NP_036067.2"
                     /db_xref="CCDS:CCDS29201.1"
                     /db_xref="GeneID:26384"
                     /db_xref="MGI:MGI:1347054"
                     /translation="MKLIILEHYSQASEWAAKYIRNRIIQFNPGPDKYFTLGLPTGST
                     PLGCYQKLIEYYKNGDLSFQYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPE
                     NTHILDGNAADLQAECDAFEEKIQAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVK
                     TLAMDTILANARFFDGDLAKVPTMALTVGVGTVMDAKEVMILITGAHKAFALYKAIEE
                     GVNHMWTVSAFQQHPRTVFVCDEDATLELKVKTVKYFKGLMLVHNKLVDPLYSIKEKE
                     IQKSQSAKKPYSD"
     exon            219..320
                     /gene="Gnpda1"
                     /gene_synonym="Gnp1; GNPDA; Gnpi; oscillin"
                     /inference="alignment:Splign:2.1.0"
     exon            321..503
                     /gene="Gnpda1"
                     /gene_synonym="Gnp1; GNPDA; Gnpi; oscillin"
                     /inference="alignment:Splign:2.1.0"
     exon            504..688
                     /gene="Gnpda1"
                     /gene_synonym="Gnp1; GNPDA; Gnpi; oscillin"
                     /inference="alignment:Splign:2.1.0"
     exon            689..863
                     /gene="Gnpda1"
                     /gene_synonym="Gnp1; GNPDA; Gnpi; oscillin"
                     /inference="alignment:Splign:2.1.0"
     exon            864..2300
                     /gene="Gnpda1"
                     /gene_synonym="Gnp1; GNPDA; Gnpi; oscillin"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2262..2267
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gnpda1"
                     /gene_synonym="Gnp1; GNPDA; Gnpi; oscillin"
                     /note="putative"
ORIGIN      
        1 gcgcgcaccc cgtgaccggt ggccacgtga cgctcgcggg ccgggccgct agtgctgtag
       61 ctgctgcagc cgcgggaagc ctgcgagtct agcgatgaag ctcattatcc tggaacacta
      121 ttcccaggcc agtgagtggg cggccaagta tattaggaac cgtatcatcc agtttaaccc
      181 agggcctgac aagtacttca ccctggggct ccccactggg agcaccccgc ttggctgcta
      241 ccagaagctg atcgagtact ataagaatgg ggacctgtcc tttcaatatg tgaaaacctt
      301 caacatggac gagtatgtgg gtcttcctcg agaccaccca gagagttacc actccttcat
      361 gtggaataat ttcttcaagc acattgacat ccaccctgaa aacacccaca ttttggatgg
      421 aaatgcggct gacctgcagg ccgagtgtga cgcctttgag gagaagatcc aggctgccgg
      481 agggatcgaa ctctttgtcg gaggcattgg ccccgatgga cacattgcct tcaatgagcc
      541 aggctccagc ctggtgtcca ggacccgtgt gaagactctg gctatggaca ccatcctggc
      601 caacgctagg ttctttgatg gtgatcttgc caaggtgccc accatggccc tgacagtggg
      661 ggtcggcact gtcatggatg ctaaagaggt gatgatcctc atcacaggcg ctcacaaggc
      721 ctttgctctg tacaaagcca tcgaggaggg cgtgaaccac atgtggacgg tgtccgcctt
      781 tcagcagcac ccccgcactg tgtttgtgtg tgacgaggac gccaccttgg aactaaaagt
      841 gaagacagtc aaatatttca aaggtttaat gcttgttcat aacaagctgg tggaccccct
      901 gtacagtatc aaggagaagg aaattcagaa aagccaatct gcgaagaagc catacagtga
      961 ctagcctgtg ccaggacgtg gtattcagta cctcagaggg ataggcaggt ctttccagaa
     1021 agtctctgta ggagagagag tagaattact tttcagtcca ctctggctgc tgcagatctg
     1081 tggcttggta gatacatgtt aaggagtttg gctatggaga acattgttga ttataatttt
     1141 cccctttttt tttcagtact gggggctgaa cctggggcct tgtacatgcc aaggaggtgc
     1201 cttgctaact gagctatgtc cccaactttc tgcccctttt cataatggtt ttgtaaccat
     1261 ccgaagtctc catcactgac tgtaattata ttcttctgcc cctgtgcaca tgggcagcac
     1321 acgcctgtcg agaactcctg tctgtatgtg tgctttttct agagttggca gggattaggg
     1381 cttgtgcact ttggacataa cctttctgga gacttgagag cccctcttct gccagccttc
     1441 ccactgagaa ttttcatttt aaagaataca cttccagaac ttgaattatg cacaaggaag
     1501 cagcccttcc tgccagaacc aagaacctgg gggagaagcc tgtcccttgt tcccattgtg
     1561 tggattgtct ttcctgttgt cagtagctag cctttctgta aacaggcctt ctgggcatgt
     1621 ggggctaaga tggctttcac aggtaaactc aaagcttcca aaggccagcc ttgtcttgtt
     1681 ctctctcaag attccaacaa gagaaaagtg gaaaggcctc ctgtctgagc tctgttttcc
     1741 tcaacagatt cttacacact ccctagtaag gagatccgcg tgggtcacag acacgctatg
     1801 atttcagtgt ttttacccaa ggtggggagc tgacatctgc acatgcgctg tgctctgtgg
     1861 cctcctcaga gctgagtgcc aagattatac atgctactgc tctctcctcg cttaactcac
     1921 cccagcactc ccaccttcgg gtttatatcc tctgtcctca gcatcagaac taaacccttc
     1981 acccccctgt ccttcaggct cccttcccag gctcctctgc ttggccttgc tttatcttct
     2041 ctgcctctgt ggagtagtca gctgcctcct tctccgtcct tgtgcctgtc tgaagctaga
     2101 gctgcctatt tccaggagag gtctttcaga acattgccca ggcccctcca gaagtactgt
     2161 gtttggtacc agcatttgtt tgtagttttt atatgtgatt gtgctattgt tctgtgttaa
     2221 gctaatggat caatggactt gtttacaatg tgatattttc tattaaattt aatattttca
     2281 aataaaatgt gtcttttgtg
//
