LOCUS       NM_008136               2744 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus guanine nucleotide binding protein-like 1 (Gnl1),
            mRNA.
ACCESSION   NM_008136 XM_001000673
VERSION     NM_008136.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2744)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2744)
  AUTHORS   Zheng,M.H., Shi,M., Pei,Z., Gao,F., Han,H. and Ding,Y.Q.
  TITLE     The transcription factor RBP-J is essential for retinal cell
            differentiation and lamination
  JOURNAL   Mol Brain 2, 38 (2009)
   PUBMED   20017954
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2744)
  AUTHORS   Amadou,C., Ribouchon,M.T., Mattei,M.G., Jenkins,N.A., Gilbert,D.J.,
            Copeland,N.G., Avoustin,P. and Pontarotti,P.
  TITLE     Localization of new genes and markers to the distal part of the
            human major histocompatibility complex (MHC) region and comparison
            with the mouse: new insights into the evolution of mammalian
            genomes
  JOURNAL   Genomics 26 (1), 9-20 (1995)
   PUBMED   7782091
REFERENCE   4  (bases 1 to 2744)
  AUTHORS   Vernet,C., Ribouchon,M.T., Chimini,G. and Pontarotti,P.
  TITLE     Structure and evolution of a member of a new subfamily of
            GTP-binding proteins mapping to the human MHC class I region
  JOURNAL   Mamm Genome 5 (2), 100-105 (1994)
   PUBMED   8180467
REFERENCE   5  (bases 1 to 2744)
  AUTHORS   Denizot,F., Mattei,M.G., Vernet,C., Pontarotti,P. and Chimini,G.
  TITLE     YAC-assisted cloning of a putative G-protein mapping to the MHC
            class I region
  JOURNAL   Genomics 14 (4), 857-862 (1992)
   PUBMED   1478666
  REMARK    Erratum:[Genomics 1993 Sep;17(3):800]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC112970.18, BM949933.1, BC094391.1 and AV338067.2.
            
            On Jan 18, 2007 this sequence version replaced NM_008136.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK078187.1, SRR1660813.244527.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-254               AC112970.18        69742-69995         c
            255-854             BM949933.1         1-600
            855-2703            BC094391.1         292-2140
            2704-2744           AV338067.2         622-662
FEATURES             Location/Qualifiers
     source          1..2744
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 18.82 cM"
     gene            1..2744
                     /gene="Gnl1"
                     /gene_synonym="Gna-rs1; Gnal1"
                     /note="guanine nucleotide binding protein-like 1"
                     /db_xref="GeneID:14670"
                     /db_xref="MGI:MGI:95764"
     exon            1..293
                     /gene="Gnl1"
                     /gene_synonym="Gna-rs1; Gnal1"
                     /inference="alignment:Splign:2.1.0"
     CDS             221..2044
                     /gene="Gnl1"
                     /gene_synonym="Gna-rs1; Gnal1"
                     /note="GTP-binding protein MMR1; guanine nucleotide
                     binding protein, related sequence 1"
                     /codon_start=1
                     /product="guanine nucleotide-binding protein-like 1"
                     /protein_id="NP_032162.2"
                     /db_xref="CCDS:CCDS37606.1"
                     /db_xref="GeneID:14670"
                     /db_xref="MGI:MGI:95764"
                     /translation="MPRKKPFSVKQKKKQLQDKRERKRGLQDGLRSSSNSRSGSRERR
                     EEQTDTSDGESVTHHIRRLNQQPSQGLGPRGYDPNRYRLHFERDSREEVERRKRAARE
                     QVLQPVSAEVLELDIREVYQPGSVLDFPRRPPWSYEMSKEQLMSQEERSFQEYLGKIH
                     GAYTSEKLSYFEHNLETWRQLWRVLEMSDIVLLITDIRHPVVNFPPALYEYVTGELGL
                     ALVLVLNKVDLAPPALVVAWKHYFHQCYPQLHIVLFTSFPRDTRTPQEPGGVLKKNRR
                     RGKGWTRALGPEQLLRACEAITVGKVDLSSWREKIARDVAGASWGNVSGEEEEEEDGP
                     AVLVEQLTDSAMEPTGPSRERYKDGVVTIGCIGFPNVGKSSLINGLVGRKVVSVSRTP
                     GHTRYFQTYFLTPSVKLCDCPGLIFPSLLPRQLQVLAGIYPIAQIQEPYTSVGYLASR
                     IPVQALLHLRHPEAEDPSAEHPWCAWDICEAWAEKRGYKTAKAARNDVYRAANSLLRL
                     AVDGRLSLCFYPPGYSEQRGTWESHPETAELVLSQGRVGPAGDEEEEEEEELSSSCEE
                     EGEEDRDADEEGEGDEDTPTSDPGSCLTARNPYALLGEDEC"
     exon            294..459
                     /gene="Gnl1"
                     /gene_synonym="Gna-rs1; Gnal1"
                     /inference="alignment:Splign:2.1.0"
     exon            460..596
                     /gene="Gnl1"
                     /gene_synonym="Gna-rs1; Gnal1"
                     /inference="alignment:Splign:2.1.0"
     exon            597..748
                     /gene="Gnl1"
                     /gene_synonym="Gna-rs1; Gnal1"
                     /inference="alignment:Splign:2.1.0"
     exon            749..820
                     /gene="Gnl1"
                     /gene_synonym="Gna-rs1; Gnal1"
                     /inference="alignment:Splign:2.1.0"
     exon            821..1028
                     /gene="Gnl1"
                     /gene_synonym="Gna-rs1; Gnal1"
                     /inference="alignment:Splign:2.1.0"
     exon            1029..1124
                     /gene="Gnl1"
                     /gene_synonym="Gna-rs1; Gnal1"
                     /inference="alignment:Splign:2.1.0"
     exon            1125..1319
                     /gene="Gnl1"
                     /gene_synonym="Gna-rs1; Gnal1"
                     /inference="alignment:Splign:2.1.0"
     exon            1320..1498
                     /gene="Gnl1"
                     /gene_synonym="Gna-rs1; Gnal1"
                     /inference="alignment:Splign:2.1.0"
     exon            1499..1661
                     /gene="Gnl1"
                     /gene_synonym="Gna-rs1; Gnal1"
                     /inference="alignment:Splign:2.1.0"
     exon            1662..1802
                     /gene="Gnl1"
                     /gene_synonym="Gna-rs1; Gnal1"
                     /inference="alignment:Splign:2.1.0"
     exon            1803..2744
                     /gene="Gnl1"
                     /gene_synonym="Gna-rs1; Gnal1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2128..2133
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gnl1"
                     /gene_synonym="Gna-rs1; Gnal1"
                     /note="hexamer: AATAAA"
     polyA_site      2149
                     /gene="Gnl1"
                     /gene_synonym="Gna-rs1; Gnal1"
                     /note="major polyA site"
     polyA_site      2703
                     /gene="Gnl1"
                     /gene_synonym="Gna-rs1; Gnal1"
ORIGIN      
        1 cgcgcgtctc ccgctcgccg caccgtgcat cccggacccg cggactctca cgtgccgccg
       61 cttgcatccc cgccgccccg ctccccgctc cccgccgctc gctgctgacg tcaccgcggc
      121 cccgcctccc cagggccccg ggccgccggc gggggctgcc ccggggagtc agttgcggcg
      181 gcggggagct cggcggaggg cgggccgggg ctccggggcc atgccgagga agaagccctt
      241 cagcgtgaag cagaagaaga agcagctgca ggacaagcgg gagcggaagc gagggctcca
      301 agatgggctg cgctccagtt ccaacagccg cagcggtagc cgggagcggc gggaggagca
      361 gacggacacg tcggatgggg aatccgtgac ccatcatatc cgcaggctca accagcaacc
      421 ttcccagggc ctggggccca gaggctacga ccccaaccga taccggctgc attttgaacg
      481 ggacagccgg gaggaggtgg agaggagaaa gagagcggcc agagagcaag tgttgcagcc
      541 ggtcagtgct gaagtgttag agttggatat ccgggaagtg tatcagcctg gctcagtcct
      601 ggactttccc cggcggcctc cttggagtta tgagatgtcc aaggaacagc taatgagcca
      661 ggaggagcgg agcttccagg aataccttgg gaagatacac ggggcataca cttcagagaa
      721 actcagctac tttgagcaca atctggagac atggaggcag ctgtggcggg tgttagagat
      781 gtctgacatc gtcctgctca ttactgacat ccgacatccg gttgtgaact tcccaccagc
      841 actttacgag tatgtaactg gagagcttgg gctggccctg gtgctggtct tgaacaaggt
      901 ggacctggcc ccgccggctc tcgtggttgc ctggaagcat tattttcacc agtgctaccc
      961 ccagctccac attgtcttgt tcacctcttt ccctcgggac acgcgcactc cacaggagcc
     1021 tggtggtgtc ttgaagaaga atcggagacg ggggaaagga tggactcggg cactgggacc
     1081 agagcagttg ctgagagcct gtgaagctat cactgtgggg aaagtggact tgagcagctg
     1141 gcgcgagaag attgctaggg acgtggctgg agcctcctgg ggtaacgtct ccggtgagga
     1201 agaggaggag gaagacgggc cagcagtact ggtagagcag ctgaccgact cagccatgga
     1261 gcccacaggc ccctccaggg agcgctacaa ggatggggtg gtgactattg gctgtatagg
     1321 tttccccaat gtggggaagt cctctctgat caacgggctg gtggggcgga aggtggtgag
     1381 tgtctccaga acgccaggcc acacccggta ttttcagacc tactttctga ccccctctgt
     1441 gaagctctgt gactgcccgg gccttatctt cccctcgctg ctgcccaggc agctgcaggt
     1501 tctggctgga atctacccca ttgcccagat ccaggagccc tacacttctg tgggctacct
     1561 ggcctccaga atccccgtgc aggccctgct gcacctgcgc cacccagagg cagaggaccc
     1621 ttcggctgag cacccctggt gtgcctggga catctgtgaa gcttgggcag agaaacgtgg
     1681 ttataaaacg gccaaggcag ctcgaaatga cgtgtacaga gcggccaata gcctacttcg
     1741 cctggcagtg gatggccgcc tcagcctatg tttctaccct cctggttaca gcgaacagag
     1801 aggcacctgg gagtctcacc cagagactgc agagctggtg ctgtcgcagg gcagggtggg
     1861 gccggcaggt gatgaggagg aggaagagga ggaggaactg agcagctcct gtgaggagga
     1921 aggagaggag gaccgggatg cagatgaaga gggagaagga gatgaggaca ccccaacttc
     1981 agatcctggg tcctgcctaa cagcccgaaa cccgtatgcc ctgctcgggg aggatgagtg
     2041 ctgagcccca cctggtacca cgtccccctc agcagctttg cttctgggct gagctggagg
     2101 tgtcttccct ttgccaccct gattgtgaat aaagattgtc tgctttgtag ccccttcccc
     2161 aggtggcctg aggtgagagc ggtcggtgtg ggctgaccgc tgtgggaggc tttttgcctt
     2221 tcttcttcat tctctttggg aagcagagct atctgaggcc gctgcccact ctctcacata
     2281 gcactttagg aatccccatg gacagaggag gtctatggca ggctcacctg gtattagccc
     2341 tcctctcctt cacttcaaca gagtcctgtt accccctgtt gcctggcctt ggttttacga
     2401 gcgctttgtg ggtgaaggag ccgtggaggt gtgtcaccac ggaagctttt tatagggatt
     2461 ttctagactc agtgaacatt tatcaaatct gtgtctggga ctgtgctaag tacaaaaccc
     2521 tttgtatggt gccggagcca ggactgctcg tgacccagac ctcatggagc acagactttg
     2581 ggattaagat gggtgtgtga aggttctcca aattctgggg acctgtggat tatattctgg
     2641 aacttactga tactgaaatg taaatatgac aaaaagcttg tgaaaaaaaa ttaatgaaac
     2701 gtgtgcaggc ggagacttaa ttatagcaaa cagcattcac tgtt
//
