LOCUS       NM_001412473            1327 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus guanine nucleotide binding protein (G protein), gamma
            8 (Gng8), transcript variant 4, mRNA.
ACCESSION   NM_001412473 XM_011250436
VERSION     NM_001412473.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1327)
  AUTHORS   Kolla,L., Kelly,M.C., Mann,Z.F., Anaya-Rocha,A., Ellis,K.,
            Lemons,A., Palermo,A.T., So,K.S., Mays,J.C., Orvis,J., Burns,J.C.,
            Hertzano,R., Driver,E.C. and Kelley,M.W.
  TITLE     Characterization of the development of the mouse cochlear
            epithelium at the single cell level
  JOURNAL   Nat Commun 11 (1), 2389 (2020)
   PUBMED   32404924
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1327)
  AUTHORS   Assens,A., Dal Col,J.A., Njoku,A., Dietschi,Q., Kan,C.,
            Feinstein,P., Carleton,A. and Rodriguez,I.
  TITLE     Alteration of Nrp1 signaling at different stages of olfactory
            neuron maturation promotes glomerular shifts along distinct axes in
            the olfactory bulb
  JOURNAL   Development 143 (20), 3817-3825 (2016)
   PUBMED   27578798
REFERENCE   3  (bases 1 to 1327)
  AUTHORS   Montani,G., Tonelli,S., Sanghez,V., Ferrari,P.F., Palanza,P.,
            Zimmer,A. and Tirindelli,R.
  TITLE     Aggressive behaviour and physiological responses to pheromones are
            strongly impaired in mice deficient for the olfactory G-protein
            -subunit G8
  JOURNAL   J Physiol 591 (16), 3949-3962 (2013)
   PUBMED   23836683
REFERENCE   4  (bases 1 to 1327)
  AUTHORS   Kerr,D.S., Von Dannecker,L.E., Davalos,M., Michaloski,J.S. and
            Malnic,B.
  TITLE     Ric-8B interacts with G alpha olf and G gamma 13 and co-localizes
            with G alpha olf, G beta 1 and G gamma 13 in the cilia of olfactory
            sensory neurons
  JOURNAL   Mol Cell Neurosci 38 (3), 341-348 (2008)
   PUBMED   18462949
REFERENCE   5  (bases 1 to 1327)
  AUTHORS   Hurowitz,E.H., Melnyk,J.M., Chen,Y.J., Kouros-Mehr,H., Simon,M.I.
            and Shizuya,H.
  TITLE     Genomic characterization of the human heterotrimeric G protein
            alpha, beta, and gamma subunit genes
  JOURNAL   DNA Res 7 (2), 111-120 (2000)
   PUBMED   10819326
REFERENCE   6  (bases 1 to 1327)
  AUTHORS   Downes,G.B., Gilbert,D.J., Copeland,N.G., Gautam,N. and
            Jenkins,N.A.
  TITLE     Chromosomal mapping of five mouse G protein gamma subunits
  JOURNAL   Genomics 57 (1), 173-176 (1999)
   PUBMED   10191100
REFERENCE   7  (bases 1 to 1327)
  AUTHORS   Williams,C.J., Schultz,R.M. and Kopf,G.S.
  TITLE     G protein gene expression during mouse oocyte growth and
            maturation, and preimplantation embryo development
  JOURNAL   Mol Reprod Dev 44 (3), 315-323 (1996)
   PUBMED   8858601
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC148981.7.
            
            On Sep 30, 2022 this sequence version replaced XM_011250436.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: ERR3363660.1526971.1,
                                           SRR17784647.527174.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-595               AC148981.7         19153-19747         c
            596-657             AC148981.7         18998-19059         c
            658-756             AC148981.7         18290-18388         c
            757-1125            AC148981.7         16482-16850         c
            1126-1327           AC148981.7         16073-16274         c
FEATURES             Location/Qualifiers
     source          1..1327
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 9.15 cM"
     gene            1..1327
                     /gene="Gng8"
                     /gene_synonym="G(y)8; Hg3e"
                     /note="guanine nucleotide binding protein (G protein),
                     gamma 8"
                     /db_xref="GeneID:14709"
                     /db_xref="MGI:MGI:109163"
     exon            1..595
                     /gene="Gng8"
                     /gene_synonym="G(y)8; Hg3e"
                     /inference="alignment:Splign:2.1.0"
     exon            596..657
                     /gene="Gng8"
                     /gene_synonym="G(y)8; Hg3e"
                     /inference="alignment:Splign:2.1.0"
     exon            658..756
                     /gene="Gng8"
                     /gene_synonym="G(y)8; Hg3e"
                     /inference="alignment:Splign:2.1.0"
     exon            757..1125
                     /gene="Gng8"
                     /gene_synonym="G(y)8; Hg3e"
                     /inference="alignment:Splign:2.1.0"
     CDS             1042..1254
                     /gene="Gng8"
                     /gene_synonym="G(y)8; Hg3e"
                     /note="gamma-9; guanine nucleotide binding protein (G
                     protein), gamma 8 subunit; heterotrimeric guanine
                     nucleotide-binding protein 3e"
                     /codon_start=1
                     /product="guanine nucleotide-binding protein
                     G(I)/G(S)/G(O) subunit gamma-8"
                     /protein_id="NP_001399402.1"
                     /db_xref="GeneID:14709"
                     /db_xref="MGI:MGI:109163"
                     /translation="MSNNMAKIAEARKTVEQLKLEVNIDRMKVSQAAAELLAFCETHA
                     KDDPLVTPVPAAENPFRDKRLFCTLL"
     exon            1126..1327
                     /gene="Gng8"
                     /gene_synonym="G(y)8; Hg3e"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1298..1303
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gng8"
                     /gene_synonym="G(y)8; Hg3e"
                     /note="hexamer: AATAAA"
     polyA_site      1327
                     /gene="Gng8"
                     /gene_synonym="G(y)8; Hg3e"
                     /note="major polyA site"
ORIGIN      
        1 acacccacag catgctctct ccctataggc acggcctccg ccgtgtggtc cagcggggaa
       61 ggctccctct gtctctcttg tctcttggca ggcttgactc ggtctctgag tgtctgtctc
      121 caaggctcag tctgtgtatc tgtctcctgt ggcctctccc tgtgcatcca tcatctatcc
      181 ttcgtctgtc tctctgtgaa cttagttctg tttctctttg cagttctcac cgccctctga
      241 agttctctgt cccattttcc gtcctctcac tctgatccct cactactttc accttcctag
      301 ggagccatct ccctctctta tccttcttgg gtcccccaga tctcccgttt ctatcttctg
      361 ctgggcggac ggggacgcct agtcttcgcc tcttcttctg cttgagctcc tgcagcgact
      421 ttggttcgcg ggcgccaccg tgtggccaat agggagtcct tgatggcggc gaggcaagca
      481 agcgatgctg tggtctggat gcgacgtcca gaggtggtgc gacccacgcc agtgtaaggg
      541 cacgcctcag aggtggtgtg ggacgccagc agatgatgtg tgactgtgtg acaagcgaga
      601 ctgtgggcca ctgtgtatgg cattggacct gagagaggac ctgcctggag actgttcgca
      661 atggagcgct tggcagtgag gctgaaccag tatgtggttg tgtgagactc caagacagtg
      721 tgaatgcgaa cttcaggaga agttaaagct gcactgcctc ccatcctgtg tatccatccc
      781 tccttccttt cccagcccct ctgctcttcc tccagcagcc tcttgatacc tccatccgtg
      841 cacccctcca tcctgtcttc ttgagtcgtc atcctttcct ctacctgtct ctgggatccc
      901 attcactcat agtcccaacc acgtctcctg ttactgactg ggtcacgcca cctcttctcg
      961 ctactccccg ggggatccaa gagtgttcca gcccccagtc cacactcctg ccagacattt
     1021 aacccctttc ctgctgcagc catgtccaac aacatggcca agattgctga ggcccgcaag
     1081 accgtggagc agctgaagct ggaagtgaac atcgatcgca tgaaggtgtc gcaggcagca
     1141 gccgagcttt tggctttctg cgaaacgcac gctaaggatg acccactggt gactcctgtc
     1201 cctgccgccg agaatccctt ccgcgacaag cgactctttt gcaccctgct ctgagccctc
     1261 aagacagctt tatcctcccc cgcagaagta tgaatccaat aaacttggtg acctggtggt
     1321 gcctgca
//
