LOCUS       NM_001406264            3452 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus guanine nucleotide binding protein (G protein), gamma
            7 (Gng7), transcript variant 4, mRNA.
ACCESSION   NM_001406264 XM_036155619
VERSION     NM_001406264.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3452)
  AUTHORS   Yim,Y.Y., McDonald,W.H., Betke,K.M., Kaya,A., Hyde,K., Erreger,K.,
            Gilsbach,R., Hein,L. and Hamm,H.E.
  TITLE     Specificities of Gbetagamma subunits for the SNARE complex before
            and after stimulation of alpha2a-adrenergic receptors
  JOURNAL   Sci Signal 14 (714), eabc4970 (2021)
   PUBMED   34932372
REFERENCE   2  (bases 1 to 3452)
  AUTHORS   Brunori,G., Pelletier,O.B., Stauffer,A.M. and Robishaw,J.D.
  TITLE     Selective Manipulation of G-Protein gamma7 Subunit in Mice Provides
            New Insights into Striatal Control of Motor Behavior
  JOURNAL   J Neurosci 41 (44), 9065-9081 (2021)
   PUBMED   34544837
  REMARK    GeneRIF: Selective Manipulation of G-Protein gamma7 Subunit in Mice
            Provides New Insights into Striatal Control of Motor Behavior.
REFERENCE   3  (bases 1 to 3452)
  AUTHORS   Halder,S.K., Sasaki,K. and Ueda,H.
  TITLE     Ggamma7-specific prothymosin alpha deletion causes stress- and
            age-dependent motor dysfunction and anxiety
  JOURNAL   Biochem Biophys Res Commun 522 (1), 264-269 (2020)
   PUBMED   31759625
  REMARK    GeneRIF: Ggamma7-specific prothymosin alpha deletion causes stress-
            and age-dependent motor dysfunction and anxiety.
REFERENCE   4  (bases 1 to 3452)
  AUTHORS   Sasaki,K., Omotuyi,O.I., Ueda,M., Shinohara,K. and Ueda,H.
  TITLE     NMDA receptor agonists reverse impaired psychomotor and cognitive
            functions associated with hippocampal Hbegf-deficiency in mice
  JOURNAL   Mol Brain 8 (1), 83 (2015)
   PUBMED   26637193
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3452)
  AUTHORS   Xie,K., Masuho,I., Shih,C.C., Cao,Y., Sasaki,K., Lai,C.W.,
            Han,P.L., Ueda,H., Dessauer,C.W., Ehrlich,M.E., Xu,B.,
            Willardson,B.M. and Martemyanov,K.A.
  TITLE     Stable G protein-effector complexes in striatal neurons: mechanism
            of assembly and role in neurotransmitter signaling
  JOURNAL   Elife 4, e10451 (2015)
   PUBMED   26613416
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 3452)
  AUTHORS   Williams,C.J., Schultz,R.M. and Kopf,G.S.
  TITLE     G protein gene expression during mouse oocyte growth and
            maturation, and preimplantation embryo development
  JOURNAL   Mol Reprod Dev 44 (3), 315-323 (1996)
   PUBMED   8858601
REFERENCE   7  (bases 1 to 3452)
  AUTHORS   Mbikay,M., Seidah,N.G., Chretien,M. and Simpson,E.M.
  TITLE     Chromosomal assignment of the genes for proprotein convertases PC4,
            PC5, and PACE 4 in mouse and human
  JOURNAL   Genomics 26 (1), 123-129 (1995)
   PUBMED   7782070
REFERENCE   8  (bases 1 to 3452)
  AUTHORS   Avraham,S., Jiang,S., Ota,S., Fu,Y., Deng,B., Dowler,L.L.,
            White,R.A. and Avraham,H.
  TITLE     Structural and functional studies of the intracellular tyrosine
            kinase MATK gene and its translated product
  JOURNAL   J Biol Chem 270 (4), 1833-1842 (1995)
   PUBMED   7530249
REFERENCE   9  (bases 1 to 3452)
  AUTHORS   Danielson,P.E., Watson,J.B., Gerendasy,D.D., Erlander,M.G.,
            Lovenberg,T.W., de Lecea,L., Sutcliffe,J.G. and Frankel,W.N.
  TITLE     Chromosomal mapping of mouse genes expressed selectively within the
            central nervous system
  JOURNAL   Genomics 19 (3), 454-461 (1994)
   PUBMED   7910582
REFERENCE   10 (bases 1 to 3452)
  AUTHORS   Cali,J.J., Balcueva,E.A., Rybalkin,I. and Robishaw,J.D.
  TITLE     Selective tissue distribution of G protein gamma subunits,
            including a new form of the gamma subunits identified by cDNA
            cloning
  JOURNAL   J Biol Chem 267 (33), 24023-24027 (1992)
   PUBMED   1385432
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC152500.7.
            
            On May 11, 2022 this sequence version replaced XM_036155619.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17784650.87631.1, BY236169.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-53                AC152500.7         83338-83390
            54-106              AC152500.7         100202-100254
            107-218             AC152500.7         129704-129815
            219-334             AC152500.7         145300-145415
            335-3452            AC152500.7         146500-149617
FEATURES             Location/Qualifiers
     source          1..3452
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 39.72 cM"
     gene            1..3452
                     /gene="Gng7"
                     /gene_synonym="Hg3b"
                     /note="guanine nucleotide binding protein (G protein),
                     gamma 7"
                     /db_xref="GeneID:14708"
                     /db_xref="MGI:MGI:95787"
     exon            1..53
                     /gene="Gng7"
                     /gene_synonym="Hg3b"
                     /inference="alignment:Splign:2.1.0"
     exon            54..106
                     /gene="Gng7"
                     /gene_synonym="Hg3b"
                     /inference="alignment:Splign:2.1.0"
     exon            107..218
                     /gene="Gng7"
                     /gene_synonym="Hg3b"
                     /inference="alignment:Splign:2.1.0"
     exon            219..334
                     /gene="Gng7"
                     /gene_synonym="Hg3b"
                     /inference="alignment:Splign:2.1.0"
     CDS             254..460
                     /gene="Gng7"
                     /gene_synonym="Hg3b"
                     /note="guanine nucleotide binding protein (G protein),
                     gamma 7 subunit; heterotrimeric guanine nucleotide-binding
                     protein 3b"
                     /codon_start=1
                     /product="guanine nucleotide-binding protein
                     G(I)/G(S)/G(O) subunit gamma-7"
                     /protein_id="NP_001393193.1"
                     /db_xref="GeneID:14708"
                     /db_xref="MGI:MGI:95787"
                     /translation="MSGTNNVAQARKLVEQLRIEAGIERIKVSKASSDLMGYCEQHAR
                     NDPLLVGVPASENPFKDKKPCIIL"
     exon            335..3452
                     /gene="Gng7"
                     /gene_synonym="Hg3b"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3434..3439
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gng7"
                     /gene_synonym="Hg3b"
                     /note="hexamer: AATAAA"
     polyA_site      3452
                     /gene="Gng7"
                     /gene_synonym="Hg3b"
                     /note="major polyA site"
ORIGIN      
        1 aggccccgcg gtgcgttcgg ctgtgcggct gctgagacac tggctggagg cagggtgtga
       61 agcctttcta ttggaacctc agtgctggga cggtgggacg gtgcagggtc ttgggatgtg
      121 tcctcgggta ctgaagaggc actactgtaa cagggatcac agcaacatta gtgtcctggt
      181 gcatgctggg agaaggtact cagaacctgg aggagcagct ctctagacgc caggtccacg
      241 ctcatggccg atgatgtcag gtactaacaa cgtcgcccag gcccggaagc tggtggagca
      301 gctgcgcatt gaagctggga tcgaacgcat caaggtctcc aaggcctcgt cagacctgat
      361 gggctactgt gagcaacatg cccgcaacga tcccttgctg gttggcgtgc cagcctctga
      421 gaatccattc aaagacaaaa agccttgcat aattctctag ttctctctct ttctctctct
      481 cttccccatc tctccctctc tttctcccca ccccggaggt attggtccaa tttttcctgt
      541 aaggaaaata tttgaatcct tcccactttg aattctaaag gaacaaaaac cattgtgaat
      601 gccgggatct tcctgaccta gctggagttt atgaacccag gtggggctct gactgtcgcc
      661 tggcctaact gagatgttag cctcgtcacc cccaccccct cttttcaaga gtcactactg
      721 tggcccattt ttaaagctcc ccttagttgc cttggggaaa gggctccgtt gataaacggg
      781 attgccttgc aagcgtgagg accctaggtg cggcgcggtc ctcaggtccc acagaaagca
      841 tgcaggtgca gtgtcacaag gttgtatgta cttcagcact tggtaggcaa ggcagaaggg
      901 tccccagggc ttgagggact gccattctag ttgtcagtaa actccagaca gaggaggaca
      961 cccagccttg acctctggct ccacccgcgc ggggcacaca caatgcaccc tgtgctgccc
     1021 tgtgtccttc cagagtggcc ctgtcatgta cacagtgacg ccatttctcc agagacatgg
     1081 cccattccag agacgggcat ctgggtctcc attcaaagga agctcttgct ggtatgaccg
     1141 agtgtgtaat tttgtctcct aagcctgaga tccacgtggt cattggtggc tccccatttt
     1201 ctcccagtta cacagttatc caggtagttg tgagggcaga aatgcagatt agttatctct
     1261 cgaggtgatc gaggagtgac ggggttctcc gtcccacatc gtgactgtgg ctccagatcc
     1321 ccctgcctcc ttcctaggac aaactatttt gtaactagct agaatccaag cccctcagtg
     1381 tggggactgt agccctggtc tgcactccca gattggggga ttctaggcag ggctccaccc
     1441 agaccacacc ccaatgagga tttggggact ctaggcgggg ctccaccccg aactgcgacc
     1501 tcagcccctt actggggcat tctaggtggg gctctacatt gaccactccc ccagcccctc
     1561 actgggagat tgtagtctgg ggctccaccc tgaccacgcc cctagaccct tgttggtaga
     1621 ttctccacag cattctaccc ctgagccagg cctcttctct ttctattttg tgaacagagc
     1681 cctagagtcc aggctggcct ggaacaggag atcttcctgc ctctgtctcc agagtaccta
     1741 catgacggtc ttgtgcttgc atgcctggca ttggattgga ctgaagaaaa catgccctct
     1801 gtctgtaaca gtgacagtgg caggtatagg gaggacacga cttgggtgtg ccaatgcggt
     1861 gtgcagccac acacagaggc agcctaagca tttgaaagac cccagctgcc tctttctcct
     1921 gccagatcag tatgggagca aaccgcagaa ctgaagccag tctagttgtt ccctgtatcc
     1981 ctggtggaaa tctgctgcca aaagcctggg ccaggctgat ccctgggcaa agtgaaaggg
     2041 gtgagcacag ttagctcatc ttctagccag ttaggcatga cctaccgcct aggtaaggtg
     2101 gcaggctccc ccaaatccat ttgatggaaa caggaaaaga agtctggggt gtgactaagg
     2161 ggaggcattg caggtgctaa gagcgccccc ctcccacttc cccctccatg ggctgggtcc
     2221 cagagagcac agaccaaggg tctggcttct gtgcatcagc tcccattact ggtcagagag
     2281 ggccagcaac tttggtcagc ctgactctca gaacctggct tgagtcagaa aagccagttt
     2341 cccccaccct caaactacag ccaccttgca ttaggctagg aaccaggtcc caggatgtgt
     2401 gtccccagct acactggcaa ggagaaagga aagctggaaa tctggggacc agggctgcag
     2461 agcacccacc cagcatgctg gaaagctggg ttccacccca agctcgaagt aaccaggcac
     2521 gggcactggg gtaggcagat caggacttca gggtcttcct cagctacata atgggctcaa
     2581 ggctaacctg gactacatga gaccatgtct caaattcagt gcactctctc actctctcac
     2641 atcacgacag cagatgcctg cctggccagc ctgtgtgtgg tcggagcatt ttgtttctct
     2701 cctctgggac aaaaaactca aatctgcatc tctgcccaca cttccagttc tccctcccta
     2761 ggtgactcac aggccaagga caaagtgact tcttgttccc aaggaaggta ggacgtgctt
     2821 ggctgatgta tccaggatgg accttgggcc ccaatagccc ttgtgtgccc tcctaaccac
     2881 tggagccctg cctcagctta gagatactta gggaaaccag aacacaacag agccatcagg
     2941 agccaagatt gggggccctc accttcaatc ccaacacttg ggagacagag gcaaggggat
     3001 ctccgtgaat tcgaggccag cctcatctac agagtgagtt ccaggacagc cagggttgta
     3061 gagacaccgt ctaaaaacaa aataaaacaa ccaaaactgt tagacctgct gcagcttgag
     3121 ccacccagga gggacttcca acctaaggag aaggttggtg ggcatggggg ggtgtatcct
     3181 acacagaagc catatacact ggccagatgt cacatggcac tttccatttc cgtccccact
     3241 tcagggctgg ctcctccccc tcacgctcca gggctggctc ctaccccttc agactcctcc
     3301 cccttccctc tgctttgtga agctggttgg tttttatttc tgattaaaaa aaaaactttt
     3361 tcccgtgtgc cacgcccact ctcccagtgt tactattgtg tggaatgagg tcacaggaga
     3421 gtgactcctc cataataaaa gcctcgattt tc
//
