LOCUS       NM_001357782             386 bp    mRNA    linear   ROD 16-OCT-2024
DEFINITION  Mus musculus guanine nucleotide binding protein (G protein), gamma
            13 (Gng13), transcript variant 2, mRNA.
ACCESSION   NM_001357782 XM_006524779
VERSION     NM_001357782.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 386)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 386)
  AUTHORS   Lei,H., Yu,D., Xue,Y.B., Li,Y.H., Gong,S.M., Peng,Y.Y., Liu,K.F.,
            Buratto,D., Yang,Y., Zhang,S.S., Wu,M., Zhou,R. and Huang,L.
  TITLE     Tuft cells utilize taste signaling molecules to respond to the
            pathobiont microbe Ruminococcus gnavus in the proximal colon
  JOURNAL   Front Immunol 14, 1259521 (2023)
   PUBMED   37954611
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 386)
  AUTHORS   Garcia-Alonso,L., Lorenzi,V., Mazzeo,C.I., Alves-Lopes,J.P.,
            Roberts,K., Sancho-Serra,C., Engelbert,J., Mareckova,M.,
            Gruhn,W.H., Botting,R.A., Li,T., Crespo,B., van Dongen,S.,
            Kiselev,V.Y., Prigmore,E., Herbert,M., Moffett,A., Chedotal,A.,
            Bayraktar,O.A., Surani,A., Haniffa,M. and Vento-Tormo,R.
  TITLE     Single-cell roadmap of human gonadal development
  JOURNAL   Nature 607 (7919), 540-547 (2022)
   PUBMED   35794482
REFERENCE   4  (bases 1 to 386)
  AUTHORS   Yim,Y.Y., McDonald,W.H., Betke,K.M., Kaya,A., Hyde,K., Erreger,K.,
            Gilsbach,R., Hein,L. and Hamm,H.E.
  TITLE     Specificities of Gbetagamma subunits for the SNARE complex before
            and after stimulation of alpha2a-adrenergic receptors
  JOURNAL   Sci Signal 14 (714), eabc4970 (2021)
   PUBMED   34932372
REFERENCE   5  (bases 1 to 386)
  AUTHORS   Sanfilippo,C., Musumeci,G., Kazakova,M., Mazzone,V.,
            Castrogiovanni,P., Imbesi,R. and Di Rosa,M.
  TITLE     GNG13 Is a Potential Marker of the State of Health of Alzheimer's
            Disease Patients' Cerebellum
  JOURNAL   J Mol Neurosci 71 (5), 1046-1060 (2021)
   PUBMED   33057964
REFERENCE   6  (bases 1 to 386)
  AUTHORS   Huang,L., Max,M., Margolskee,R.F., Su,H., Masland,R.H. and Euler,T.
  TITLE     G protein subunit G gamma 13 is coexpressed with G alpha o, G beta
            3, and G beta 4 in retinal ON bipolar cells
  JOURNAL   J Comp Neurol 455 (1), 1-10 (2003)
   PUBMED   12454992
  REMARK    GeneRIF: Ggamma13 subunit is coexpressed in physiologically ON-type
            cone bipolar cells with Gbeta3 and Gbeta4 but is not present in
            OFF-type bipolar cells.
REFERENCE   7  (bases 1 to 386)
  AUTHORS   Blake,B.L., Wing,M.R., Zhou,J.Y., Lei,Q., Hillmann,J.R., Behe,C.I.,
            Morris,R.A., Harden,T.K., Bayliss,D.A., Miller,R.J. and
            Siderovski,D.P.
  TITLE     G beta association and effector interaction selectivities of the
            divergent G gamma subunit G gamma(13)
  JOURNAL   J Biol Chem 276 (52), 49267-49274 (2001)
   PUBMED   11675383
REFERENCE   8  (bases 1 to 386)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
REFERENCE   9  (bases 1 to 386)
  AUTHORS   Inoue,S., Sano,H. and Ohta,M.
  TITLE     Growth suppression of Escherichia coli by induction of expression
            of mammalian genes with transmembrane or ATPase domains
  JOURNAL   Biochem Biophys Res Commun 268 (2), 553-561 (2000)
   PUBMED   10679242
REFERENCE   10 (bases 1 to 386)
  AUTHORS   Huang,L., Shanker,Y.G., Dubauskaite,J., Zheng,J.Z., Yan,W.,
            Rosenzweig,S., Spielman,A.I., Max,M. and Margolskee,R.F.
  TITLE     Ggamma13 colocalizes with gustducin in taste receptor cells and
            mediates IP3 responses to bitter denatonium
  JOURNAL   Nat Neurosci 2 (12), 1055-1062 (1999)
   PUBMED   10570481
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC134908.5 and EH103048.1.
            
            On Nov 10, 2017 this sequence version replaced XM_006524779.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC048431.1, AB030194.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-54                AC134908.5         91463-91516
            55-186              AC134908.5         92602-92733
            187-347             AC134908.5         92862-93022
            348-386             EH103048.1         227-265
FEATURES             Location/Qualifiers
     source          1..386
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 12.82 cM"
     gene            1..386
                     /gene="Gng13"
                     /gene_synonym="1500031D04Rik; Ggamma13; Hg3j"
                     /note="guanine nucleotide binding protein (G protein),
                     gamma 13"
                     /db_xref="GeneID:64337"
                     /db_xref="MGI:MGI:1925616"
     exon            1..54
                     /gene="Gng13"
                     /gene_synonym="1500031D04Rik; Ggamma13; Hg3j"
                     /inference="alignment:Splign:2.1.0"
     exon            55..186
                     /gene="Gng13"
                     /gene_synonym="1500031D04Rik; Ggamma13; Hg3j"
                     /inference="alignment:Splign:2.1.0"
     CDS             89..292
                     /gene="Gng13"
                     /gene_synonym="1500031D04Rik; Ggamma13; Hg3j"
                     /note="heterotrimeric guanine nucleotide-binding protein
                     3j"
                     /codon_start=1
                     /product="guanine nucleotide-binding protein
                     G(I)/G(S)/G(O) subunit gamma-13"
                     /protein_id="NP_001344711.1"
                     /db_xref="CCDS:CCDS37503.1"
                     /db_xref="GeneID:64337"
                     /db_xref="MGI:MGI:1925616"
                     /translation="MEEWDVPQMKKEVESLKYQLAFKREMSSKTIPELLKWIEDGIPK
                     DPFLNPDLMKNNPWVEKAKCTIL"
     exon            187..362
                     /gene="Gng13"
                     /gene_synonym="1500031D04Rik; Ggamma13; Hg3j"
                     /inference="alignment:Splign:2.1.0"
     regulatory      325..330
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gng13"
                     /gene_synonym="1500031D04Rik; Ggamma13; Hg3j"
                     /note="hexamer: TATAAA"
     polyA_site      344
                     /gene="Gng13"
                     /gene_synonym="1500031D04Rik; Ggamma13; Hg3j"
                     /note="major polyA site"
ORIGIN      
        1 gggggcgtct cggggtgcac cggcggccgg gctccggcgg cggcagcagc gcagcctcag
       61 gctggctacc accgacgccc ccgacgccat ggaggagtgg gatgtgcccc agatgaagaa
      121 ggaggtagag agcctcaagt accaactggc cttcaagagg gagatgtcgt ccaagaccat
      181 ccccgagctt ctcaagtgga ttgaggatgg aatccccaag gaccccttcc tgaacccaga
      241 cctgatgaag aacaaccctt gggtagagaa ggccaagtgc accatcctat gagcctgacc
      301 cacactctct gtaaggtgtg actttataaa tagacttctc cgggtgtctc tgctttagtc
      361 caaaaaaaaa aaaaaaaaaa aaaaaa
//
