LOCUS       NM_020273               6518 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus glucocorticoid modulatory element binding protein 1
            (Gmeb1), transcript variant 1, mRNA.
ACCESSION   NM_020273
VERSION     NM_020273.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6518)
  AUTHORS   Tuesta,L.M., Djekidel,M.N., Chen,R., Lu,F., Wang,W., Sabatini,B.L.
            and Zhang,Y.
  TITLE     In vivo nuclear capture and molecular profiling identifies Gmeb1 as
            a transcriptional regulator essential for dopamine neuron function
  JOURNAL   Nat Commun 10 (1), 2508 (2019)
   PUBMED   31175277
  REMARK    GeneRIF: Gmeb1 knockdown in midbrain dopamine (mDA) neurons
            resulted in downregulation of tyrosine hydroxylase and dopamine
            transporter, as well as in severe motor deficits. This study thus
            identifies Gmeb1 as a master regulator of mDA gene expression and
            function.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6518)
  AUTHORS   Wiese,C.B., Ireland,S., Fleming,N.L., Yu,J., Valerius,M.T.,
            Georgas,K., Chiu,H.S., Brennan,J., Armstrong,J., Little,M.H.,
            McMahon,A.P. and Southard-Smith,E.M.
  TITLE     A genome-wide screen to identify transcription factors expressed in
            pelvic Ganglia of the lower urinary tract
  JOURNAL   Front Neurosci 6, 130 (2012)
   PUBMED   22988430
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6518)
  AUTHORS   L'Hote,D., Georges,A., Todeschini,A.L., Kim,J.H., Benayoun,B.A.,
            Bae,J. and Veitia,R.A.
  TITLE     Discovery of novel protein partners of the transcription factor
            FOXL2 provides insights into its physiopathological roles
  JOURNAL   Hum Mol Genet 21 (14), 3264-3274 (2012)
   PUBMED   22544055
REFERENCE   4  (bases 1 to 6518)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   5  (bases 1 to 6518)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   6  (bases 1 to 6518)
  AUTHORS   Yoshikawa,T., Piao,Y., Zhong,J., Matoba,R., Carter,M.G., Wang,Y.,
            Goldberg,I. and Ko,M.S.
  TITLE     High-throughput screen for genes predominantly expressed in the ICM
            of mouse blastocysts by whole mount in situ hybridization
  JOURNAL   Gene Expr Patterns 6 (2), 213-224 (2006)
   PUBMED   16325481
REFERENCE   7  (bases 1 to 6518)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   8  (bases 1 to 6518)
  AUTHORS   Powles,N., Babbs,C., Ficker,M., Schimmang,T. and Maconochie,M.
  TITLE     Identification and analysis of genes from the mouse otic vesicle
            and their association with developmental subprocesses through in
            situ hybridization
  JOURNAL   Dev Biol 268 (1), 24-38 (2004)
   PUBMED   15031102
REFERENCE   9  (bases 1 to 6518)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   10 (bases 1 to 6518)
  AUTHORS   Jimenez-Lara,A.M., Heine,M.J. and Gronemeyer,H.
  TITLE     Cloning of a mouse glucocorticoid modulatory element binding
            protein, a new member of the KDWK family
  JOURNAL   FEBS Lett 468 (2-3), 203-210 (2000)
   PUBMED   10692587
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK134349.1, BU701415.1, CN459906.1 and BX537301.12.
            
            On Apr 4, 2008 this sequence version replaced NM_020273.1.
            
            Transcript Variant: This variant (1) and variant 2 encode the same
            protein.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK134349.1, SRR7345562.1412600.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164142, SAMN01164143
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-245               AK134349.1         2-246
            246-965             BU701415.1         93-812
            966-1505            CN459906.1         35-574
            1506-6518           BX537301.12        46751-51763         c
FEATURES             Location/Qualifiers
     source          1..6518
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 64.99 cM"
     gene            1..6518
                     /gene="Gmeb1"
                     /gene_synonym="1110050A04Rik"
                     /note="glucocorticoid modulatory element binding protein
                     1"
                     /db_xref="GeneID:56809"
                     /db_xref="MGI:MGI:2135604"
     exon            1..59
                     /gene="Gmeb1"
                     /gene_synonym="1110050A04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            60..217
                     /gene="Gmeb1"
                     /gene_synonym="1110050A04Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             90..1778
                     /gene="Gmeb1"
                     /gene_synonym="1110050A04Rik"
                     /note="GMEB-1"
                     /codon_start=1
                     /product="glucocorticoid modulatory element-binding
                     protein 1"
                     /protein_id="NP_064669.2"
                     /db_xref="CCDS:CCDS18720.1"
                     /db_xref="GeneID:56809"
                     /db_xref="MGI:MGI:2135604"
                     /translation="MANAEVSVPVGDVVVVPTEGNEGENPEDTKTQVILQLQPVQQGI
                     YEAGSENSAAVVAVETHSIHKIEEGIDASSIEGNEDMEIAYPITCGESKAVLLWKKFV
                     CPGINVKCVKFNDQLISPKHFVHLAGKSTLKDWKRAIRLGGIMLRKMMDSGQIDFYQH
                     DKVCSNTCRSTKFDLLISSARAPVPGQQTSVVQTPTSADGNITQIAISEESMEEAGLE
                     WNSALTAAVTMATEEGIKKESEEISEDTLMFWKGIADVGLMEEVVCNIQKEMEELLRG
                     VQQRLIQAPFQVTDAAVLNNVANTFGLMDAVKRVLDNRRKQVEQGEEQFLYTLADLER
                     QLEEQKKQAQDPRLKSQTVQNVVLMPVSTPKPPKRPRLQRPASTTVLSPSPVQQPQFT
                     VISPITITPVGQSFSMGNIPVATLSQGSSPVTVHTLPSGPQLFRYATVVSSAKSNSPD
                     TVTIHPSSSLALLSSTSMQDGSSLGNMATMVSPMELVAMESGLTSAIQAVESTSEDGQ
                     TIIEIDPAPDSEADDTEGKAVILETGLRTEEKVVAEMEEHQHQVHNVEIVVLED"
     exon            218..300
                     /gene="Gmeb1"
                     /gene_synonym="1110050A04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            301..425
                     /gene="Gmeb1"
                     /gene_synonym="1110050A04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            426..529
                     /gene="Gmeb1"
                     /gene_synonym="1110050A04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            530..687
                     /gene="Gmeb1"
                     /gene_synonym="1110050A04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            688..819
                     /gene="Gmeb1"
                     /gene_synonym="1110050A04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            820..957
                     /gene="Gmeb1"
                     /gene_synonym="1110050A04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            958..1080
                     /gene="Gmeb1"
                     /gene_synonym="1110050A04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1081..6518
                     /gene="Gmeb1"
                     /gene_synonym="1110050A04Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1891..1896
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gmeb1"
                     /gene_synonym="1110050A04Rik"
                     /note="hexamer: AACAAA"
     polyA_site      1915
                     /gene="Gmeb1"
                     /gene_synonym="1110050A04Rik"
                     /note="major polyA site"
     regulatory      4563..4568
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gmeb1"
                     /gene_synonym="1110050A04Rik"
                     /note="hexamer: AATAAA"
     polyA_site      4587
                     /gene="Gmeb1"
                     /gene_synonym="1110050A04Rik"
                     /note="major polyA site"
     regulatory      4872..4877
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gmeb1"
                     /gene_synonym="1110050A04Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      4916
                     /gene="Gmeb1"
                     /gene_synonym="1110050A04Rik"
     polyA_site      4927
                     /gene="Gmeb1"
                     /gene_synonym="1110050A04Rik"
     regulatory      6225..6230
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gmeb1"
                     /gene_synonym="1110050A04Rik"
                     /note="hexamer: AATGAA"
     polyA_site      6247
                     /gene="Gmeb1"
                     /gene_synonym="1110050A04Rik"
     regulatory      6268..6273
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gmeb1"
                     /gene_synonym="1110050A04Rik"
                     /note="hexamer: TATAAA"
     regulatory      6275..6280
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gmeb1"
                     /gene_synonym="1110050A04Rik"
                     /note="hexamer: AACAAA"
     polyA_site      6286
                     /gene="Gmeb1"
                     /gene_synonym="1110050A04Rik"
     polyA_site      6292
                     /gene="Gmeb1"
                     /gene_synonym="1110050A04Rik"
ORIGIN      
        1 tgctccgtcg cccgcccgcc ctggccgctc gccgcccgcc cgcccgcccg acggagacgc
       61 agccccagct agctgacttc atgtgaaaga tggccaatgc agaagtgagc gtcccagtgg
      121 gagatgtggt tgtggtaccc actgaaggaa atgaagggga gaacccggaa gacactaaaa
      181 ctcaagtgat cttgcagtta cagcctgtgc aacaagggat ttatgaagct gggtcggaga
      241 atagcgcagc agttgtagcc gtagagaccc actcaataca caaaatcgag gaaggaattg
      301 atgcaagcag tatagaaggg aacgaggaca tggagatcgc ttaccctata acctgtgggg
      361 agagtaaagc tgtcctcctc tggaagaagt tcgtgtgtcc aggaataaac gtgaagtgtg
      421 tcaagtttaa tgaccagctg atcagtccca agcacttcgt tcacctggct ggcaagtcca
      481 ccctgaagga ctggaagaga gccatccgtc taggcggcat catgctcagg aagatgatgg
      541 actctggaca gatcgatttt taccagcatg acaaagtttg ctccaatacc tgcaggagca
      601 ccaaatttga cctcctgatc agcagtgcga gggctccagt gccaggacag cagacaagtg
      661 tggtgcagac ccccacctcg gccgatggga acatcacaca gatcgccatc tcagaggaga
      721 gcatggaaga ggcagggctg gagtggaact cagctctcac cgccgctgtc accatggcca
      781 cagaggaggg tataaagaaa gagtctgaag agatttcaga ggacactttg atgttctgga
      841 aggggatagc tgatgtaggg ttgatggagg aggtcgtctg caacatccag aaggagatgg
      901 aagagctgct caggggcgtt cagcagcggc tcattcaggc ccctttccag gtcacagatg
      961 ctgctgttct aaacaatgtg gcgaacacat ttggcctaat ggacgcggtc aagagagttt
     1021 tggacaacag acggaagcaa gtggagcagg gcgaggagca gtttctctac accctggcag
     1081 acttggaacg gcagttggag gagcaaaaaa agcaagccca agatcccaga ctgaaatccc
     1141 agacagttca aaatgtggta ctgatgcccg tgagcacccc aaagcctcca aaaagacccc
     1201 ggctccagcg gccagcctcc accaccgtcc tgagcccttc tcccgtccag cagcctcagt
     1261 ttactgtcat ctctcccatc accattactc ctgtgggcca gtccttctcc atgggcaaca
     1321 tcccagtggc taccctcagc cagggctcca gtcctgtgac tgtccacaca ctgccttctg
     1381 gccctcagct cttccgctat gccacggtgg tttcctctgc caagagcaac tcaccagaca
     1441 cagtgaccat ccacccttcc tcaagtttgg cactgctaag ctccacctct atgcaggatg
     1501 ggagttccct gggcaacatg gccaccatgg tgagccccat ggagctggtg gccatggagt
     1561 ccggcctgac gtcagcaatc caggctgttg aaagcacctc tgaggatggg cagaccatca
     1621 ttgaaatcga ccctgcccca gactccgagg ctgacgacac tgagggcaaa gcagtcatct
     1681 tggagacagg gctgaggact gaggagaaag tggtagccga aatggaagaa caccagcatc
     1741 aggtccacaa tgtggagatt gtggtcttgg aggactgatt ggggacaggg ccaagagctg
     1801 tgttttggtt tggaatttta attatgttta tttttatcat tgtcccgctc atttccacat
     1861 agaacttttt ttaaaaaaaa aacaaaaaca aacaaaaaaa aaccaaacta caaaatctcg
     1921 ttgtaactgc aaatgttggg ttcctcctac ttcctcattg acaactggac agaacaagct
     1981 gcctttccag aagttagaaa cagggcaccc agggtctgaa ccatctttcc ccaaggaagg
     2041 taattgcttt taggggaagt gtcaaaatat ccaggaatcc tttccagaat agtctgtctg
     2101 tgtatacacg catggtctca ctcttgtaaa gacgcattga ccagaccctg gaacacagat
     2161 ctgactccag aagatgacca gctctgctgt ggatacagaa gcacgcttgc ctctgtgtcc
     2221 tggatatgat ggcctcagat gctggtgtgc aaaactgaaa gaacaggagg ttggctctgc
     2281 ttagggtgga aagtagtgtg atcagcagct cataggggga gccctttgac agggaggggc
     2341 cgaggaatgg tcttccagag gtgcatctga tgccccttgc gctctctgag ggttgggtac
     2401 cattttcaat ttcagaagag gacagagatt atagaaagac acaaagcaat caaaagattg
     2461 tcacagctgt gcttttggga tagctcacct tgcccccagc cttgtcaaag ccctcaccct
     2521 cctcgcccag gactatcagt ccattccttt gcagactgtg atgtggtata aattgttcta
     2581 attcttggac tgtggctgtc atggaggtgg ggctccaagg ccatcatttt tcgtttcttg
     2641 actccaggaa tggcagagtc cctcgtgcag accagctgct atttttggtg gagccctgca
     2701 cgtaagcatg caagtgtgtg tgtgtgtgtg tgtatgtgtg tgtgtgtgtg tgtgtgtgtg
     2761 tgtgtgtaca tgtttcgggt ttggaaccaa aagcagtcat ttccctggtg cttccttttc
     2821 ttttccttcc gtctgctgga ccccatgctc agtagctttt tggcagacag cagtgacagg
     2881 tgcctgcctg ccttcattct ctttgccatt ctcctcttct gataccacag atgtttctgt
     2941 gagataccga actcataaaa tggcttaggc ttggcaggga caactggtaa cacctttcct
     3001 gaggtgtgga ctagatggct cctgagtgag ctgcactttc tgggaaaggg acattgtatt
     3061 tgacattgta agaagtatga caggagtgtc agtaacgtcc aggcgtgggg cttcttccta
     3121 aatgctgttt gtacattcgg tactactagg tcactctttc tgctgtgatc ccatgtcgtt
     3181 gattctcttc agcgtttggg ggagagtaag cagtttctgg tttctttaat tatattgttt
     3241 actatgttag ggaaaatata gagactctcg aggtgacttt ataggtcaaa aaagcataca
     3301 gcttaggagc tggaggattt attattatta ttaaaagtaa aattttggct tttgtttaaa
     3361 aaaaaaaaat agagaaggat gcctgtctaa atctgtcttc ctgcctgcag gttttgaaaa
     3421 ccctgtaagc aaccaaaagt tgcaccttcc atctcttaga cggccatgtg tcaccaggga
     3481 agcaagccct cagggatcac tctgaagacc ctgaagagtg cggcttctga actctattca
     3541 gatttgtttc agctttaaaa ctggactttt cttttcagac tctttagtta ggctggggac
     3601 agaactgaat tggtaaagtg gtcacctagc gttcatgaaa ccctgggctc agtctccagc
     3661 cagaagtaaa ctgggcatgg ggccacatat ctgatcctaa cacttgggaa atagagacgg
     3721 gagacttaga aattcaaggt catacatacc aagttcaaga ccaacctggg atatatgaaa
     3781 tagtgtctca aaaaattttt gtttaggaca agcttttggt gaaagaagga atttattcct
     3841 gccttcctta cactttgtta atacatagga atttttatta catttattta tctgtgtgtg
     3901 tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgatggtgag cttgctacgg tatgtatgtg
     3961 aagatcagag aacaacctgc aggagtctgt tctcgccttc caccatgtgg gtcctgggaa
     4021 ttgaactcag gttgccaggc ttggtggtaa gcaccctcat ccattgagcc atcttgcctg
     4081 ctctaaaagt ttcggtcttc agaccaaaac tgttacttga acctagaaag ccacatcgca
     4141 tccctgttgt gtcctttagg tcatttctct tttccagaga tgggcagacc aattcaggac
     4201 acgggaggca ccctagagaa tagaggcagg ctccttcagg tcctgccttt ttgctcttca
     4261 cagctgttgt gtcattaaag gttgtgtgag cagcatgctt ccaaagtcag atttccttct
     4321 tgagacagag cctgtttact taaaacagat tacatgagct ttgctgtttt cctggtcttc
     4381 caattgctgt cattgctagc tgcagtggta cttggagaga tgagatctct cacagacctg
     4441 gtctagatta ttttaggtgg ggtgatacac atgcaagctt ctgatgtgtg aataggcagt
     4501 tgcaatgaaa ttactcctca ggctgacttg atggtagcta tcttttctct agccattcat
     4561 taaataaaca tttgtaagta ctgtctatgt ataagtacta aacgccaact gattgcgtca
     4621 cctaagcccc agtaagtacc atgaagatgc aggttttgtg ctagacactg atcttgcaga
     4681 caagacaatt cctgttctta agaagttcat acccagacat ctttgcagtt aaccacactt
     4741 tttgtttgtt tggtttgttt tttgagacag ggtttctctg tgtagccctg gctgtcctgg
     4801 aactctcact atgtagccag gctgactgga actcacagag atctgtttgc ctctgtcttc
     4861 caagtgctgg gattaaaggt gtgcaccacc actgccatag tgaatagtca accgtatttt
     4921 aatgtcattg gtttcttttg tgatcctgtt ttatcttaaa tattgggaag gactctgagt
     4981 ctttagttcc taggtttcaa caggcaaagt cacagaggtg aagccacccc tggtgagatt
     5041 ttaccttagg ttgaggtgac tgtagctatg gtcttttttt ttttttttaa agatttattt
     5101 atttattata tgtaagtaca ctgtagctgt cttcagacac tccagaagag ggagtcagat
     5161 cttgttacag atggctgtga gccaccatgt ggttgctggg atttgaactc tggaccttcg
     5221 gaagaacagt cgggtgctct tacccactga gccatctcac cagccccagc tatggtcttt
     5281 tggcctggag ttaagcacaa aagatcaagc acttactcag cttggggtct gaatggcttc
     5341 cgctaatctg aggcagttct ctgcataccc tagttgccct tgaacttggc tatgtagagt
     5401 agcctggctt tgagctcata aaggtccatc tgcctctgcc tcctaagcat tgggattaaa
     5461 gctatcacac ttggctcttg ctactcctca gtttctaggc ttccaaagag tggtgctgca
     5521 tgcgtgcctg gggccccggc cccagagggc aggggcaaga agagagaaag cttcaagatc
     5581 ctgtctcaca aaccagaaat ttaggcttcc acatcccaaa cccaaagtta ctctactttt
     5641 gtttgtgtcg ctcccccctc ccccatggac aatagacatt caagattcaa acccactttg
     5701 gtgtgtcgtt ccctcacctg ccatagcagg agagagaact aatatagatg aatagcaggt
     5761 gattctttta atgttgctgg tttgtcccat ttcatgagag acactataga taagtatata
     5821 tggggagtac tgattttatt tacaaaaaaa aaaaatgtac atttagtgtg cttgtgtgtg
     5881 tgtggcatgc cggagtacat ggtgtcttta tcaatgaaca gctttcagga ttcagttctc
     5941 gccttccact gtgtgggtcc caggggtcaa attcagtttg ccaggcttgg caagcaagca
     6001 cctctactca ctgagctatc ttgctggccc aatgagattt tttctttttc atgtatttat
     6061 tttagtttat aattgttctt gcaagtatgt atgtgcacct cacctctcac gcatgcctgg
     6121 tatctgacgt ggttggtcgg agaacatttc tgatcccctg gaactggtgt tagagatggt
     6181 gtctgctacc atgtgggcgc tggaaatcca acccaggttc tctgaatgaa tacatgctct
     6241 caactgagct gtctcttcgg gtgatattat aaataacaaa actgttgtga aatatggagt
     6301 cattgagtca gaactgaccc ataatggagg actatctagg agatggaaaa gaatccttcc
     6361 ctcaaccctc cccaaaaaag gttgaattct gaaattaagc acaaagtggt ggtggcacac
     6421 atctttgatc ccagcacgta ggagccagtt ggatctctga gttcaaggcc agacttgtct
     6481 cgaggacagc caaggctaca cagagaaatc acatcttg
//
