LOCUS       NM_001033362             751 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus predicted gene 614 (Gm614), transcript variant 1,
            mRNA.
ACCESSION   NM_001033362
VERSION     NM_001033362.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 751)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 751)
  AUTHORS   He,Y., Xu,R., Zhai,B., Zhou,S., Wang,X. and Wang,R.
  TITLE     Gm614 Protects Germinal Center B Cells From Death by Suppressing
            Caspase-1 Transcription in Lupus-Prone Mice
  JOURNAL   Front Immunol 11, 585726 (2020)
   PUBMED   33193409
  REMARK    GeneRIF: Gm614 Protects Germinal Center B Cells From Death by
            Suppressing Caspase-1 Transcription in Lupus-Prone Mice.
            Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK131750.1, AL671926.11 and AV045544.3.
            
            [WARNING] On Aug 20, 2024 this sequence was replaced by
            NM_001033362.4.
            
            On Nov 24, 2015 this sequence version replaced NM_001033362.2.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK131750.1, AV045544.3 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-556               AK131750.1         2-557
            557-557             AL671926.11        152778-152778       c
            558-747             AK131750.1         559-748
            748-751             AV045544.3         622-625
FEATURES             Location/Qualifiers
     source          1..751
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 43.9 cM"
     gene            1..751
                     /gene="Gm614"
                     /note="predicted gene 614"
                     /db_xref="GeneID:245536"
                     /db_xref="MGI:MGI:2685460"
     exon            1..168
                     /gene="Gm614"
                     /inference="alignment:Splign:2.1.0"
     CDS             144..719
                     /gene="Gm614"
                     /note="isoform 1 is encoded by transcript variant 1;
                     uncharacterized protein CXorf65 homolog"
                     /codon_start=1
                     /product="uncharacterized protein CXorf65 homolog isoform
                     1"
                     /protein_id="NP_001028534.1"
                     /db_xref="CCDS:CCDS30311.1"
                     /db_xref="GeneID:245536"
                     /db_xref="MGI:MGI:2685460"
                     /translation="MFIIIKHGDNQEFLVNSNCSVLLLLHYIRKKMKLRKTDTIDLCD
                     ESGTMKLLFLSKTPGDSASKFLTARNTYYVCKVERGAPGTRIENSYKAIVPMLKNPEP
                     ELVDSLRTQCDFLERSRIKMLRTLEAKRLAAMESSVNLPARSPKGGGAQQTTSTSSQL
                     KSKGGRSDEDGPPSTRRPFYKTRADFLKRHR"
     exon            169..255
                     /gene="Gm614"
                     /inference="alignment:Splign:2.1.0"
     exon            256..390
                     /gene="Gm614"
                     /inference="alignment:Splign:2.1.0"
     exon            391..459
                     /gene="Gm614"
                     /inference="alignment:Splign:2.1.0"
     exon            460..626
                     /gene="Gm614"
                     /inference="alignment:Splign:2.1.0"
     exon            627..751
                     /gene="Gm614"
                     /inference="alignment:Splign:2.1.0"
     regulatory      723..728
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gm614"
                     /note="hexamer: AATACA"
     polyA_site      748
                     /gene="Gm614"
                     /note="major polyA site"
ORIGIN      
        1 gtctgcctag tctgggcctc ctccagtctc taaaataatc tgctccttca tgcccaaccc
       61 ctatgcttag gaccctaggg tcctagagca ccttccatct gcatgatcca tcaaggggtg
      121 aaggatgaaa tgacataagt agcatgttta tcatcatcaa acatggagac aatcaagagt
      181 ttctggtcaa ttccaattgc tctgtcctcc tgttgctaca ttacatccga aagaaaatga
      241 aattacggaa aacagacacc attgatttgt gtgatgaatc gggaaccatg aagttactct
      301 tcctgtcaaa gacacctgga gactctgcca gcaaattcct tacagctcga aatacctact
      361 atgtttgtaa agtggaacgt ggggcaccag gtaccagaat tgagaattcc tacaaagcta
      421 ttgtgcccat gctgaagaat ccagaacctg aactagttga ctcgctgcgc acacaatgtg
      481 acttcctgga gaggagcaga ataaagatgc ttagaactct agaagccaag agactggcag
      541 ccatggaatc ctctgtaaat ctcccagcaa ggtctcccaa gggtggtgga gcccagcaga
      601 ctactagcac aagcagtcaa ctgaagtcta aaggtgggcg atcagatgaa gacggaccac
      661 cttccacccg cagaccattc tacaagacta gagcagactt tctcaagaga catcgttaac
      721 tcaatacaaa gaccaagtga gagcagcagc t
//
