LOCUS       NM_053251               1622 bp    mRNA    linear   ROD 05-AUG-2023
DEFINITION  Mus musculus predicted gene 4736 (Gm4736), mRNA.
ACCESSION   NM_053251
VERSION     NM_053251.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1622)
  AUTHORS   Qi X, Ren SW, Zhang F and Wang YQ.
  TITLE     The involvement of proline-rich protein Mus musculus predicted gene
            4736 in ocular surface functions
  JOURNAL   Int J Ophthalmol 9 (8), 1121-1126 (2016)
   PUBMED   27588265
  REMARK    GeneRIF: MP4 and Prb1 are closely related with the physiology and
            pathological processes of the ocular surface. MP4 and Prb1 might
            contribute to homeostasis of ocular surface or pathogenesis of
            diseases like dry eye.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1622)
  AUTHORS   Roberts SG, Layfield R, Bannister AJ and McDonald CJ.
  TITLE     Gene sequence of mouse B-type proline-rich protein MP4.
            Transcriptional start point and an upstream phylogenetic footprint
            with ets-like and rel/NFkB-like elements
  JOURNAL   Eur J Biochem 202 (3), 969-974 (1991)
   PUBMED   1765104
REFERENCE   3  (bases 1 to 1622)
  AUTHORS   Roberts SG, Layfield R and McDonald CJ.
  TITLE     The mouse proline-rich protein MP6 promoter binds
            isoprenaline-inducible parotid nuclear proteins via a highly
            conserved NFkB/rel-like site
  JOURNAL   Nucleic Acids Res 19 (19), 5205-5211 (1991)
   PUBMED   1747160
  REMARK    Erratum:[Nucleic Acids Res 1991 Oct 25;19(20):5812]
REFERENCE   4  (bases 1 to 1622)
  AUTHORS   Clements,S., Mehansho,H. and Carlson,D.M.
  TITLE     Novel multigene families encoding highly repetitive peptide
            sequences. Sequence analyses of rat and mouse proline-rich protein
            cDNAs
  JOURNAL   J Biol Chem 260 (25), 13471-13477 (1985)
   PUBMED   3840480
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC132581.4.
            
            On Dec 22, 2019 this sequence version replaced NM_053251.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BY709066.1, BF536391.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-92                AC132581.4         57405-57496
            93-128              AC132581.4         58487-58522
            129-1622            AC132581.4         59381-60874
FEATURES             Location/Qualifiers
     source          1..1622
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 64.03 cM"
     gene            1..1622
                     /gene="Gm4736"
                     /gene_synonym="EG114600; Mp4; Mp6"
                     /note="predicted gene 4736"
                     /db_xref="GeneID:100502592"
                     /db_xref="MGI:MGI:3647826"
     exon            1..92
                     /gene="Gm4736"
                     /gene_synonym="EG114600; Mp4; Mp6"
                     /inference="alignment:Splign:2.1.0"
     CDS             29..1267
                     /gene="Gm4736"
                     /gene_synonym="EG114600; Mp4; Mp6"
                     /note="proline-rich proteoglycan 2-like; proline rich
                     protein MP4"
                     /codon_start=1
                     /product="proline rich protein MP4 precursor"
                     /protein_id="NP_444481.2"
                     /db_xref="GeneID:100502592"
                     /db_xref="MGI:MGI:3647826"
                     /translation="MLVVLLTAALLVLSSAQRQDEEITYEDSNSQLLERGEKSQGYGH
                     HFPKPPPGGMPPRPPSSDENNDGDEDGSEEDVNRPEGPPQHPPHPGHHHGPPQQGGPQ
                     GPPRPGNQQGPPPPGPPPQGSPQQRPPQPGKQQGPPPQGGSQGPPMPVNQQGPPPKGG
                     PQQRPPQPGNQQGPPPQGGPQQRPPQPGNQQGPPPQGGPQQRPPQPGNQQGPPPQGGP
                     QGPPRPGNQQGPPPQGGPQRPPQPGNQQGRPPQGGPQERPPQPGNQQGPHPQGGLQGP
                     PRPGNQQGPPPKGSPQGPPMPGNQQGPPPQGGLQQRPPQAGNPQGPPPQGGPQGHPRP
                     GNQQGPPPQGGPQQRPPQPGNQQGPPQQEGPQGPPRPGNQQGPPPQGGPQRPSQPGNH
                     QGPPQHGNNEQPNYLWSLFA"
     exon            93..128
                     /gene="Gm4736"
                     /gene_synonym="EG114600; Mp4; Mp6"
                     /inference="alignment:Splign:2.1.0"
     exon            129..1622
                     /gene="Gm4736"
                     /gene_synonym="EG114600; Mp4; Mp6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agcacaacct tgggagcaat cttccaagat gctggttgtc ctgctcacag cagctttgct
       61 ggtcctgagc tcagctcaga gacaagatga agagatcacc tacgaagact caaattctca
      121 gctcctagag aggggagaga agagccaagg gtatggtcat cattttccaa aaccacctcc
      181 tggaggaatg cccccaagac ctcccagttc tgatgaaaat aatgatggtg atgaagatgg
      241 cagtgaggaa gatgtgaata gaccagaggg accaccacag caccctcctc acccaggaca
      301 ccaccatggt cctccccaac agggaggccc acagggtccc cctaggccgg gaaaccaaca
      361 aggcccaccc cctccaggcc cacccccaca gggaagcccc cagcagagac cccctcagcc
      421 tggaaaacaa caaggcccac caccacaggg aggttctcag ggacccccta tgcctgtaaa
      481 ccaacaaggc ccacccccaa agggaggccc ccagcaaaga ccccctcagc ctggaaacca
      541 acaaggccca cccccacagg gaggccccca gcagagaccc cctcagcctg gaaaccaaca
      601 aggcccaccc ccacagggag gcccccagca gagaccacct cagcctggaa accaacaagg
      661 accaccccca cagggaggcc cacagggacc ccctaggcct ggtaaccaac aaggcccacc
      721 tccacaggga ggtcctcaga gaccccctca gcctggaaac caacaaggtc gacccccaca
      781 gggaggcccc caggagagac ctcctcagcc tggaaaccaa caaggcccac acccacaggg
      841 aggcctacag ggacccccta ggcctggtaa ccaacaaggc ccacctccaa agggaagtcc
      901 tcagggaccc cctatgcctg gaaaccaaca aggcccaccc ccacagggag gcctccagca
      961 gagacctcct caggctggaa acccacaagg cccgccccca cagggaggcc cccagggaca
     1021 cccaagacct ggtaaccaac aaggcccacc tccacaggga ggcccccagc agagaccccc
     1081 tcagcctgga aaccaacaag gcccacccca acaggaaggc cctcagggac ctcctaggcc
     1141 tggaaaccaa caaggcccac ccccacaggg aggccctcag agaccttctc agccaggaaa
     1201 ccatcaaggc ccaccccagc atggaaacaa tgaacagcca aattacctgt ggtcactttt
     1261 tgcataacca tctgtttcct taccagagag aaggtaaata aatgccccat ttttcattcc
     1321 atgctctaat cttcagtgat gaccaccctg ttcctagaga catagatctt ggatacatct
     1381 aaaacatgaa taatctttat aattctgtgg tgtatgtgat ttaaattcac tcagtcaact
     1441 gtgaaactct aacagattta tccaagaaac taaaagatat ttaggatatg ttgaaattac
     1501 gcagtgtatc tttctactac caaactttgt ttctttgttt atttatttca ggtgaacaga
     1561 agacagatga cttcaatacc attcttatag cagaatgatg tcaataaaat atttagcata
     1621 ca
//
