LOCUS       NM_001388491            4028 bp    mRNA    linear   ROD 02-APR-2024
DEFINITION  Mus musculus predicted gene 27179 (Gm27179), mRNA.
ACCESSION   NM_001388491 XM_030248106
VERSION     NM_001388491.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4028)
  AUTHORS   Redelsperger,F., Raddi,N., Bacquin,A., Vernochet,C., Mariot,V.,
            Gache,V., Blanchard-Gutton,N., Charrin,S., Tiret,L., Dumonceaux,J.,
            Dupressoir,A. and Heidmann,T.
  TITLE     Genetic Evidence That Captured Retroviral Envelope syncytins
            Contribute to Myoblast Fusion and Muscle Sexual Dimorphism in Mice
  JOURNAL   PLoS Genet 12 (9), e1006289 (2016)
   PUBMED   27589388
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4028)
  AUTHORS   Dupressoir,A., Vernochet,C., Harper,F., Guegan,J., Dessen,P.,
            Pierron,G. and Heidmann,T.
  TITLE     A pair of co-opted retroviral envelope syncytin genes is required
            for formation of the two-layered murine placental
            syncytiotrophoblast
  JOURNAL   Proc Natl Acad Sci U S A 108 (46), E1164-E1173 (2011)
   PUBMED   22032925
REFERENCE   3  (bases 1 to 4028)
  AUTHORS   Church,D.M., Goodstadt,L., Hillier,L.W., Zody,M.C., Goldstein,S.,
            She,X., Bult,C.J., Agarwala,R., Cherry,J.L., DiCuccio,M.,
            Hlavina,W., Kapustin,Y., Meric,P., Maglott,D., Birtle,Z.,
            Marques,A.C., Graves,T., Zhou,S., Teague,B., Potamousis,K.,
            Churas,C., Place,M., Herschleb,J., Runnheim,R., Forrest,D.,
            Amos-Landgraf,J., Schwartz,D.C., Cheng,Z., Lindblad-Toh,K.,
            Eichler,E.E. and Ponting,C.P.
  CONSRTM   Mouse Genome Sequencing Consortium
  TITLE     Lineage-specific biology revealed by a finished genome assembly of
            the mouse
  JOURNAL   PLoS Biol 7 (5), e1000112 (2009)
   PUBMED   19468303
REFERENCE   4  (bases 1 to 4028)
  AUTHORS   Simmons,D.G., Natale,D.R., Begay,V., Hughes,M., Leutz,A. and
            Cross,J.C.
  TITLE     Early patterning of the chorion leads to the trilaminar trophoblast
            cell structure in the placental labyrinth
  JOURNAL   Development 135 (12), 2083-2091 (2008)
   PUBMED   18448564
REFERENCE   5  (bases 1 to 4028)
  AUTHORS   Mangeney,M., Renard,M., Schlecht-Louf,G., Bouallaga,I.,
            Heidmann,O., Letzelter,C., Richaud,A., Ducos,B. and Heidmann,T.
  TITLE     Placental syncytins: Genetic disjunction between the fusogenic and
            immunosuppressive activity of retroviral envelope proteins
  JOURNAL   Proc Natl Acad Sci U S A 104 (51), 20534-20539 (2007)
   PUBMED   18077339
REFERENCE   6  (bases 1 to 4028)
  AUTHORS   Dupressoir,A., Marceau,G., Vernochet,C., Benit,L.,
            Kanellopoulos,C., Sapin,V. and Heidmann,T.
  TITLE     Syncytin-A and syncytin-B, two fusogenic placenta-specific murine
            envelope genes of retroviral origin conserved in Muridae
  JOURNAL   Proc Natl Acad Sci U S A 102 (3), 725-730 (2005)
   PUBMED   15644441
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC214054.4.
            
            On Nov 17, 2020 this sequence version replaced XM_030248106.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN01164134,
                              SAMN01164140 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-216               AC214054.4         130778-130993       c
            217-413             AC214054.4         126862-127058       c
            414-4028            AC214054.4         123096-126710       c
FEATURES             Location/Qualifiers
     source          1..4028
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14"
     gene            1..4028
                     /gene="Gm27179"
                     /gene_synonym="Synb"
                     /note="predicted gene 27179"
                     /db_xref="GeneID:118567354"
                     /db_xref="MGI:MGI:5521022"
     exon            1..216
                     /gene="Gm27179"
                     /gene_synonym="Synb"
                     /inference="alignment:Splign:2.1.0"
     exon            217..413
                     /gene="Gm27179"
                     /gene_synonym="Synb"
                     /inference="alignment:Splign:2.1.0"
     exon            414..4028
                     /gene="Gm27179"
                     /gene_synonym="Synb"
                     /inference="alignment:Splign:2.1.0"
     CDS             568..2424
                     /gene="Gm27179"
                     /gene_synonym="Synb"
                     /note="syncytin-B"
                     /codon_start=1
                     /product="syncytin-B precursor"
                     /protein_id="NP_001375420.1"
                     /db_xref="GeneID:118567354"
                     /db_xref="MGI:MGI:5521022"
                     /translation="MTGFWVLCFVLFPSSLSYPESWMPLVNLTHHILRDTNSSLFSNC
                     WVCLSTQTQRSLAVPAPLSIWTDTPMKLHLTYSVRPFSGSFSISDIERRLRLFRPLTA
                     SYSFHNPDRRAIAFLQLVSSTGIFRIITRITSVIYPHKDRFFESAQRPLWGPLFTETV
                     LRSQAPLCISRFFKVSAYATFVGNLSASLCNYTMHISPSTSHENLDLSTTHTFKQAMK
                     RPDAKWKNPLRFSGPPSLIFSKPAYYPCPTDIKHCHTSPATPWMHCPQAPFGTCYNLT
                     LFEPDNSTHPVTMSVNPTHFKVKLQGHRDPYPLSHYQPLTGAALSGQYSVWENEITVQ
                     ENWDITSNIFSHLLSFSYAFCLNSSGVFFLCGTSTYICLPANWSGVCTLVFQYPDIEL
                     LPNNQTVPVPLFASVLSSDSVLRPKRSPHLFPFLAGLGISSALGTGIAGLATSTLYFQ
                     QLSKVLSETLEEIAASITTLQNQIDSLAGVVLQNRRALDLITAEKGGTCLFLQEECCF
                     YVNQSGIVRDAARKLQERASELGQHSDSWGQWPDLGRWLPWLTPFLGPLLFLFFLLTF
                     GSCLLNCLTRFVSQRLGSFVQDTAKRHVDSILQNFQYKKLPQDSPDEDTIPT"
ORIGIN      
        1 agaacctgcc tggcctacaa ctgatgctca cacctgctcc catgagagca aagggagaaa
       61 aggacgatag taagacagca agacaccgca tcccagtcag gagaccccaa ctctgtgaat
      121 tttcagagag tgaccatcga gggcaagtga cgggacccct agaggtacag cttccaaatc
      181 tcattcaccc attccgggga acactggctg tagctggttc tctccaggaa agcccgttga
      241 tctcagcctc ctaaggctca agcacagctg gttcgtcacc accttctcac tggcacttca
      301 ttcccatttc tggatgcacg gactgcttca catcttacca ccttctgcct tcatttggct
      361 cacaaacacc ttcctaaact catcctgagt cttccggaaa gggacctgcc caggtctgac
      421 ctctcacctc ataacctgag agcctacagc caccctgtct ttaccagcca cctttgaaca
      481 ccccaactga gcaagtttca ggactcaagg atccactcga ccaacgtctc ggcaccccgc
      541 actactgctg gccattccca aagcaccatg acaggctttt gggtcctctg tttcgtcctt
      601 ttcccctcct ccttatccta tccggaaagc tggatgcccc ttgtaaacct cactcaccac
      661 atcctacgtg ataccaactc ttccctgttt tccaactgtt gggtctgctt gtctacccaa
      721 acccagcggt ccttagcagt cccagcccct ctgtccattt ggacagatac acccatgaag
      781 cttcatctta cctactcagt caggcccttc tctggctcct tttccattag cgacattgaa
      841 agacgcctcc gtctcttccg cccactgact gcctcctatt ctttccacaa tcctgacaga
      901 agggcgattg cttttcttca actcgtcagc tcaacaggca tatttcggat catcacccgg
      961 ataacctctg tgatatatcc ccataaggac cgtttcttcg aatctgccca acgccctctc
     1021 tggggaccac tctttactga gaccgtgctc aggtcgcagg ccccactctg catatctcgc
     1081 tttttcaagg tctcagcata tgccactttt gtaggcaacc tctctgcctc tctctgcaac
     1141 tacaccatgc atatttcacc ttctaccagt catgaaaacc tagatctttc caccacccat
     1201 acgttcaaac aggcaatgaa aagaccggat gccaaatgga aaaacccgct ccgtttttcc
     1261 gggcccccct ccctcatctt ctcgaagccg gcttactatc cctgcccaac agacatcaaa
     1321 cactgccata cctctccggc cactccctgg atgcactgtc ctcaggctcc cttcggcacc
     1381 tgctataacc tcactttatt tgaaccagac aactcaaccc accctgttac catgtcagtg
     1441 aaccctaccc acttcaaggt caaactccag gggcacagag acccctatcc gctctcccat
     1501 taccagcccc tcacgggagc tgccctgtct ggacaatatt cagtctggga gaacgagatc
     1561 actgtccaag aaaactggga catcacctcc aacattttct cacatcttct cagcttctcg
     1621 tacgccttct gcctcaactc ttcaggcgtt ttcttcctct gcggaacatc gacttacatc
     1681 tgcctcccag ccaattggtc cggtgtctgt accctggtct tccaataccc ggatattgaa
     1741 cttctcccca ataaccaaac ggtgcctgtt cccctttttg cttcagttct ttcctcagac
     1801 tcagttcttc gcccaaagag gtcccctcac ctctttccct tccttgcagg cctgggtatc
     1861 tcttctgccc ttggtacggg gatagctggc ttggccacct cgactctcta tttccaacag
     1921 ctttctaagg ttctttccga aaccttggaa gaaatagctg cctctatcac taccctccag
     1981 aaccaaatag actcgctcgc aggtgttgtt ctacaaaacc gccgagctct ggacctcatc
     2041 actgctgaga aagggggcac ctgtctcttc ctccaggaag agtgctgctt ctacgtaaac
     2101 cagtctggaa tagtccggga cgcggcaagg aaactccaag aacgagcatc tgaactcggc
     2161 cagcattctg actcttgggg acagtggcct gaccttggac gttggttgcc ctggctgact
     2221 ccctttctgg gacctcttct cttcctcttc ttcctactga catttgggtc ttgtcttctg
     2281 aactgcctaa cccgttttgt gtcccagaga cttggctcct ttgttcaaga cactgccaaa
     2341 aggcatgtgg acagcatcct ccaaaatttc caatataaaa aactgcccca agactcccca
     2401 gatgaggaca ccattcctac ataacaggga aaagttgaga gagcaccaag tataccctcc
     2461 cttctaccca gttaatagaa tccaagtcgg gagacttagt tatggcctca tgtttgtatc
     2521 agggttaatt ccagaaacta tagtaatttg gcatccagaa aatttcttct ttttctagat
     2581 ctgagctcct tctgctcctt ctagatcttc tccttatcag tagcccccat ctcagacatg
     2641 gcctctggag ttgtttcacc tgacattctt taatccatca ctcaccttgc tgcttagcta
     2701 ctcttagcaa tggccaaaga aggaatgttt tcagtgccct gcctgtaggt ggagagtggg
     2761 ctctcttata cagagatctc tgctcccagg cctgtgctgc cagggagtgg cttgttcctc
     2821 cgttgtcttt cttgctttct gacctcatac gaagaacatt gaggtgtcag ggagcttcca
     2881 gaagctggaa gggggccagc aaggattctc tatgacagct ttgagagaga gagagagaga
     2941 gggagagaga gagagagaga ttattttttt taaataaagt ttttacagca tcatcgtatc
     3001 tttttttttt taagatttat ttatttatta tatgtaagta cactgtagct gtcttcagac
     3061 actccagaag agggcttcag atcttgttac agatggttgt gagccaccat gtggttgctg
     3121 ggatttgaac tccggacctt cagaagagca gtcgggtgct cttacccact gagccatctt
     3181 accagcccga gagagagatt attatcccct taaccttaga ctgtaccctt cagaagatat
     3241 tataaatatg tagtttcaag ctgtcagcat agcagcactt tggtactgta gatccaagac
     3301 tcatgaatca actctgatcc gtagatgtgg tagaatattt aggtggagct cttctggagc
     3361 acatgaacaa ggtgtggaga gcacaggctg gggtaggatg tacgactgag ctgggcctgg
     3421 taactgggat gggcaagagg accacaggga agggagggaa ggagagaaag gagaagtcaa
     3481 gggatgaaag agtggatggc gagagaggat tccagaggta agagcaagac gttcatgctg
     3541 gagatgttac cagagttgtt aggggcagag ctgggaccct ggcagccata gcaagctagg
     3601 cttgaccacc tgtcctcaac aagccaatca ttgtcacact taatagtgaa gaacagaaag
     3661 aaaacactta tccaatgtgg ccacactgga aaaaagaagg aagaagtctg tggagcccct
     3721 ctctcacaaa gtccacgctc tgggtcctga catgaggttt gggtttaaat agaaagcaag
     3781 agacaggcat aaggaagcag acctgtccaa gaccccgccc ttcctaccat cattgttcca
     3841 gtctggtctc ttctgcaagg gactgtctga cacatgatca gagttgtgtg taatctcttc
     3901 ctgagaggta agctcctcct aacaggcccc agccttctcc aattccagat ggaattctca
     3961 actctaaccc ctgcctgtca ctgcctgcat tcaaagaaag cccagtaaac tgaggtagtt
     4021 ctgtccca
//
