LOCUS       NM_001290127            2843 bp    mRNA    linear   ROD 18-APR-2023
DEFINITION  Mus musculus predicted gene 21992 (Gm21992), transcript variant 1,
            mRNA.
ACCESSION   NM_001290127
VERSION     NM_001290127.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2843)
  AUTHORS   Brooks YS, Wang G, Yang Z, Smith KK, Bieberich E and Ko L.
  TITLE     Functional pre- mRNA trans-splicing of coactivator CoAA and
            corepressor RBM4 during stem/progenitor cell differentiation
  JOURNAL   J Biol Chem 284 (27), 18033-18046 (2009)
   PUBMED   19416963
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC141437.4, EU287941.1 and AC147618.3.
            
            Summary: This locus represents naturally occurring readthrough
            transcription between the neighboring Rbm14 (RNA binding motif
            protein 14) and Rbm4 (RNA binding motif protein 4) genes.
            Alternative splicing results in multiple transcript variants, some
            of which encode fusion proteins that share sequence identity with
            each individual gene product. A slight modification was made to the
            summary, since not all variants are protein coding [provided by
            RefSeq, Jun 2018].
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (a).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7652917.402974.1,
                                           SRR1660811.150190.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            readthrough transcript :: includes exons from GeneID 19653, 56275
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-126               AC141437.4         99096-99221
            127-1560            EU287941.1         1-1434
            1561-1568           AC147618.3         7901-7908
            1569-2843           AC147618.3         9702-10976
FEATURES             Location/Qualifiers
     source          1..2843
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19"
     gene            1..2843
                     /gene="Gm21992"
                     /gene_synonym="Rbm14-rbm4"
                     /note="predicted gene 21992"
                     /db_xref="GeneID:102902673"
                     /db_xref="MGI:MGI:5439461"
     exon            1..463
                     /gene="Gm21992"
                     /gene_synonym="Rbm14-rbm4"
                     /inference="alignment:Splign:2.1.0"
     CDS             127..1560
                     /gene="Gm21992"
                     /gene_synonym="Rbm14-rbm4"
                     /note="isoform a is encoded by transcript variant 1;
                     transcriptional coactivator CoAZ; Rbm14/Rbm4 fusion;
                     Rbm14-Rbm4 readthrough"
                     /codon_start=1
                     /product="Rbm14-Rbm4 readthrough isoform a"
                     /protein_id="NP_001277056.1"
                     /db_xref="GeneID:102902673"
                     /db_xref="MGI:MGI:5439461"
                     /translation="MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRE
                     NAGAVRAIEALHGHELRPGRALVVEMSRPRPLNTWKIFVGNVSAACTSQELRSLFERR
                     GRVIECDVVKGCVEMVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIED
                     KTAAEDAIRNLHHYKLHGVNINVEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYG
                     PVIECDIVKDYAFVHMERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQS
                     GCYRCGKEGHWSKECPIDRSGRVADLTEQYNEQYGAVRTPYTMSYGDSLYYNNTYGAL
                     DAYYKRCRAARSYEAVAAAAASAYSNYAEQTLSQLPQVQNTAMASHLTSTSLDPYNRH
                     LLPPSGAAAAAAAAAACTAASTSYYGRDRSPLRRATGPVLTVGEGYGYGHDSELSQAS
                     AAARNSLYDMARYEREQYADRARYSAF"
     exon            464..886
                     /gene="Gm21992"
                     /gene_synonym="Rbm14-rbm4"
                     /inference="alignment:Splign:2.1.0"
     exon            887..1568
                     /gene="Gm21992"
                     /gene_synonym="Rbm14-rbm4"
                     /inference="alignment:Splign:2.1.0"
     exon            1569..2843
                     /gene="Gm21992"
                     /gene_synonym="Rbm14-rbm4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagcgcctgc gcggcggggt tctcggtcgc cagccattcc tgtggaggac tgcgggtcgt
       61 tcggacgttt tgcctgtcgc tgtaggagag gtcctgtctc tccgagaagg cggttgcggc
      121 ggcaaaatga agatttttgt gggcaatgtc gatggggcgg atacgacacc ggaggagttg
      181 gcagctctct tcgcgcccta tggcacggtc atgagctgcg ccgtcatgaa acagtttgcc
      241 ttcgtgcaca tgcgcgagaa cgctggcgcg gtgcgcgcca tcgaggccct gcatggccac
      301 gagctgcgtc caggtcgcgc gctcgtggtg gagatgtcgc gcccgaggcc cctgaacact
      361 tggaagattt tcgtgggcaa tgtatcggct gcatgtacaa gtcaggaatt gcgcagcctc
      421 ttcgagcgcc gtggacgcgt catcgagtgt gacgtggtaa aaggctgtgt ggagatggtg
      481 aagctgttca ttggaaatct gccccgggag gccacagagc aggagatccg ctcactcttc
      541 gagcagtacg ggaaggtgct ggaatgtgac atcattaaga attatggctt tgtgcacata
      601 gaggacaaga cggccgctga ggatgccata cgcaacctgc accactacaa gctgcacgga
      661 gtgaacatca atgtggaagc cagcaagaat aagagcaaag cttcaaccaa gttacacgtg
      721 ggcaacatca gccccacttg taccaaccaa gagcttcggg ccaagtttga ggagtacggc
      781 ccagtcatcg aatgtgacat cgtgaaagat tatgcctttg tacacatgga gcgggcagag
      841 gatgcggtgg aggccatcag gggcctcgac aacacagagt ttcaaggcaa acgaatgcac
      901 gtgcagttgt ccaccagccg gcttaggacc gcgcccggga tgggagacca gagcggctgc
      961 tatcggtgcg ggaaagaggg gcactggtcc aaagagtgtc caatagatcg ttcgggccgc
     1021 gtggcagact tgaccgagca atataatgag caatatggag cagtgcgtac gccttacacc
     1081 atgagttatg gggattcatt gtattacaac aacacgtacg gagcgctcga tgcctactac
     1141 aagcgctgcc gtgctgcccg gtcctatgag gcagtggcag ctgcagctgc ctctgcgtat
     1201 agtaactatg cagagcagac tttgtctcag ctgccacaag tccagaacac agccatggcc
     1261 agtcacctca cctccacctc tctcgatccc tacaatagac atctgttgcc gccttcagga
     1321 gctgcagcag cagcagcagc tgctgctgct tgtactgcag cttctacttc atattacggg
     1381 cgggatcgga gccccctgcg tcgcgctaca ggcccagtcc tcactgttgg agagggctac
     1441 ggttacgggc atgacagtga gttgtcccaa gcttcagcag ctgctcggaa ttccctgtac
     1501 gacatggccc ggtatgagcg ggagcagtat gcggatcggg cgcggtactc agccttttaa
     1561 agtttgaggt gggatgtgtg tgggctgaaa tcccaagctg cggttgtgca tgagaataca
     1621 cccttcgtgg tgccccatct ccgggacgtt ctcggctctg tgcattcagt ccccaggaac
     1681 cgtggacctt aatttacctt gttaagttct ttctctttcc tattctctct cctgctcaat
     1741 ttcctgttct cctgtttgct cttctgtagc ttcccctttg agttctgctc tcccagcatg
     1801 cctcctatgc agaaaccggt ggggctgtgc tgtctcctcc cttcctcctg actgcagtca
     1861 gtgggtattg gatttgggag tgaccttgtt gagaatcact gctcctagtt ttctattttg
     1921 gcccaaagac tagacttaga aatttggagc accttccagt gaaataaatg gtttttcaaa
     1981 ttagggtatg tgtgctttga gaaagttctt gtttgggctt gtttctgggt tctttattta
     2041 tttgtaccct gaacagaaga tgggggagtg tttaaagttt aagctactta gcttttggct
     2101 aacactgagg tttttaaatt ttgcttttta aaatagtaga tgactttagg tactaaatta
     2161 aaaaaagagg ttctacagaa ctcaagtagg catctctgtt tcaatgaaga catctcctac
     2221 tggtctactt ctgttgaagc cagttagcta gtggtttaga gctgtagatc tttacttgct
     2281 ggagaattaa tcattgtgta tacttgcatc tgctgttaac actcagtaaa catatctccc
     2341 ttgacttatt ttcaggaaaa aggtgaaggt ttgaggaaga agaggtagct ttcatctttg
     2401 ggaaaaatga aggtatggct cccacagagt tatttagcta ctccataggc cagaactacc
     2461 tcatgatgca cttcactatt tatagttctg ccaaaatcaa gagactgcat tccacaagca
     2521 tctcatagct tgtacttaat gccttcagat gaggtataaa gggcccagcg ggtcctttgt
     2581 aagtccttga taaacttact gagtctttaa cagtgaagac aagtatttgg attcagtgag
     2641 gagccactgt ttagtgtcat gtttttattg aaacagttta ttttctatgt tttattttaa
     2701 catatatagg gcctcgtctc agaatcattt atttgaccac tactggatac ctatgttgtg
     2761 tcaggcatgc ttttagtaaa gggctcatta atgataaaag gaaatatgat agagataaaa
     2821 gatgaaataa agatgagata aga
//
