LOCUS       NM_001370943            6801 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus predicted gene 14569 (Gm14569), mRNA.
ACCESSION   NM_001370943 XM_006541411
VERSION     NM_001370943.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6801)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6801)
  AUTHORS   Iwamori,T., Iwamori,N., Matsumoto,M., Ono,E. and Matzuk,M.M.
  TITLE     Identification of KIAA1210 as a novel X-chromosome-linked protein
            that localizes to the acrosome and associates with the ectoplasmic
            specialization in testes
  JOURNAL   Biol Reprod 96 (2), 469-477 (2017)
   PUBMED   28203736
  REMARK    GeneRIF: These findings suggest that KIAA1210 may be essential cell
            junction protein that interacts with TOP2B to regulate the dynamic
            change of chromatin structures during spermiogenesis.
COMMENT     INFERRED REFSEQ: This record is predicted by genome sequence
            analysis and is not yet supported by experimental evidence. The
            reference sequence was derived from AL450395.7.
            
            On Jun 15, 2019 this sequence version replaced XM_006541411.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849384
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-109               AL450395.7         185588-185696       c
            110-182             AL450395.7         184861-184933       c
            183-351             AL450395.7         177231-177399       c
            352-478             AL450395.7         172902-173028       c
            479-628             AL450395.7         163783-163932       c
            629-796             AL450395.7         131455-131622       c
            797-902             AL450395.7         129614-129719       c
            903-4898            AL450395.7         123369-127364       c
            4899-5050           AL450395.7         122253-122404       c
            5051-5147           AL450395.7         118997-119093       c
            5148-6801           AL450395.7         115442-117095       c
FEATURES             Location/Qualifiers
     source          1..6801
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 20.82 cM"
     gene            1..6801
                     /gene="Gm14569"
                     /gene_synonym="Kiaa1210"
                     /note="predicted gene 14569"
                     /db_xref="GeneID:101055983"
                     /db_xref="MGI:MGI:3705243"
     exon            1..109
                     /gene="Gm14569"
                     /gene_synonym="Kiaa1210"
                     /inference="alignment:Splign:2.1.0"
     exon            110..182
                     /gene="Gm14569"
                     /gene_synonym="Kiaa1210"
                     /inference="alignment:Splign:2.1.0"
     CDS             152..5314
                     /gene="Gm14569"
                     /gene_synonym="Kiaa1210"
                     /codon_start=1
                     /product="acrosomal protein KIAA1210"
                     /protein_id="NP_001357872.1"
                     /db_xref="GeneID:101055983"
                     /db_xref="MGI:MGI:3705243"
                     /translation="MEGFEASGEEGKKKSKFKAFKNFFSKKKKKEPEEIPEVAVLKPR
                     FSSSSVSGSSLQPALEKQVMESKPKSGMGVKSISHDSVFCLDPEPEKGAGKLHSSPAP
                     HRSKSLKIKSQRSQRLSISPLIRSEKVCEELEKFFASDRTTTTFRRRSSQCSSTPRMS
                     SELSLDPETSESSTQQFSGFSTPATSQGCLDSSAAKSKIALNPRKQKKRKSTSTPVKV
                     KQEEQLQSVPAKEKTTTKTKEAEQGEQKVDSTELSSQEQSSKTETQDTAVDKTPSTDP
                     ALRLNPRRRRRRAKNEWEILERGLLKSTQRYSLNTKAESSANKEIAGKEHSFLKLLLE
                     KKDIGQPTTTEAEVTTVQKMPSDKGDVERELADIDVEAQKEPAPQPTSTDVAESMISG
                     PSPHCEDKKKKDKVGVLPWIKKSTSQKEVTVLRKEEVQVHVHPSRVCGEGEEASCPEL
                     QRVQPQMKVSLESTTYHKEKHPRSGLPVPSTSISSATAEDDVSPKMNLPLPLRRRPNT
                     GETSSDSKSTSEYESSSEMQLSPAHSFKPTRKPKDDAGAGTADDEEDGDDEKEEKDND
                     DDDEENVFLKSENVDVEVSKMEKQQALRYSSKLLGKPKAREASAKLESSSEDERSCEE
                     MTSAHSSQSLEEFEECSESRGFIRGSISEERPATRCHSQALQELEEKEVSTESSSYIE
                     KYESSEDLSSSEQEQQVPPVSKSSLKQWSAPAKPVHPIQTAQQQPPAMVNISGGPKKS
                     GEPLSPTQTVKSRLRSQSECQVLAEPEGVVAADWDILMQPPPRPRLEQEVSAGPELTV
                     FEKSIAVQPSGYPPQPSVKPSIKKEISLGAESAPLESPPPQHHFQPLLKPFVKQQVSA
                     FERVISMDPKLPTQFQPRMKPQGKQSFSSTPESTAFEGSTSVDHMTLTLSQPMLQPYQ
                     EVPLESETVAAKMISTGQLHSKYSAHPLSSHQSQPVPESTSAEGEELLPSQPSVTPKF
                     QPLMTQGSIPSAWAIPIYSPAPRMDSKPLMGSAIALESKPSRYSLQPWQSTPFEQVSV
                     TPDHDPAAAAASWSPPIDPPTSRIPSQPLMRLAVKQPTCTELASVSVSQSSSLERLSS
                     RFPFQPRADPEHYGAEEGVATLRRSRRHHSQSPVRSEFKEEVSSGSRRAFGERSISVG
                     KMPPKYALQPWLCPEFQQQAKEGDVLRKAWLSGHPSQTISKHKVEKTPLPPKCPSPFL
                     TRSKVQEISSRLESVIAQESSKKPQRGRPPSKSFVNFMAQQVFSESAPSKVVLHPKPV
                     ARGRRRPSRSLLKPKLDDYAFLYNWDNEPKEDTTLQNLPMKQPFQLSRKPEEPQEVLP
                     FSEGAPVKWNTSARGISQALGKLSVSVSLPNEWKSSEGQLPSTQPSQAFDVAKLQSPV
                     LPVDSANVPVKWRISEGHQPPQSFFVDYQPQVSVDSASAAAKGASCWPMLKDSASTTN
                     VKYSQGYKDFTKSTPTSVIKPATFTSAPAQKPMVSMGTYFKDEVPKCCDETGTSSLLP
                     TSKADVENVFGVRLRSTSQKIGMKNPDPCKPFVLISAAARKEQANKGDLQGSVGGSKQ
                     SRPAFSFEKKQGNWPRYEGTLKKSEVFRPPGETSIWKANSPVEPAWITTLKQRQRGFV
                     SQFFKKHRTRSEISVVTKDSRYEESKHITDIPPKKTFLSSFPGCAVPHLRHFPKSVAF
                     YDQKMLHPRTRERLTRRSLSLPPTLPQREEPEWFSVAKKKAQAWSQIANIMQ"
     exon            183..351
                     /gene="Gm14569"
                     /gene_synonym="Kiaa1210"
                     /inference="alignment:Splign:2.1.0"
     exon            352..478
                     /gene="Gm14569"
                     /gene_synonym="Kiaa1210"
                     /inference="alignment:Splign:2.1.0"
     exon            479..628
                     /gene="Gm14569"
                     /gene_synonym="Kiaa1210"
                     /inference="alignment:Splign:2.1.0"
     exon            629..796
                     /gene="Gm14569"
                     /gene_synonym="Kiaa1210"
                     /inference="alignment:Splign:2.1.0"
     exon            797..902
                     /gene="Gm14569"
                     /gene_synonym="Kiaa1210"
                     /inference="alignment:Splign:2.1.0"
     exon            903..4898
                     /gene="Gm14569"
                     /gene_synonym="Kiaa1210"
                     /inference="alignment:Splign:2.1.0"
     exon            4899..5050
                     /gene="Gm14569"
                     /gene_synonym="Kiaa1210"
                     /inference="alignment:Splign:2.1.0"
     exon            5051..5147
                     /gene="Gm14569"
                     /gene_synonym="Kiaa1210"
                     /inference="alignment:Splign:2.1.0"
     exon            5148..6801
                     /gene="Gm14569"
                     /gene_synonym="Kiaa1210"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5310..5315
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gm14569"
                     /gene_synonym="Kiaa1210"
                     /note="hexamer: AATAAA"
     polyA_site      5349
                     /gene="Gm14569"
                     /gene_synonym="Kiaa1210"
                     /note="major polyA site"
     regulatory      6783..6788
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gm14569"
                     /gene_synonym="Kiaa1210"
                     /note="hexamer: AATAAA"
     polyA_site      6801
                     /gene="Gm14569"
                     /gene_synonym="Kiaa1210"
                     /note="major polyA site"
ORIGIN      
        1 agcactttgg gacgcctggc tttagccaga gcggttctgc tgtggggaac gaggcaggag
       61 ctctcgcggg gaccagcatg ggagaattct gatcgaaacc acagaaagat gaggtgctgt
      121 ggctgagtca ttaactcaag tatccagcag tatggaaggt tttgaagcct ctggagagga
      181 gggaaagaag aaatctaagt ttaaagcctt taagaacttt tttagcaaga agaagaagaa
      241 agaaccagaa gaaatcccag aagtggcagt gctaaagccc aggttttcca gcagcagtgt
      301 tagtgggtct tctctgcagc cagctctgga aaagcaagtg atggagtcca agccaaagag
      361 tggcatggga gtcaagtcca tatcccatga cagtgtcttc tgtttggatc ctgagcctga
      421 aaaaggagca ggcaagctac actcttctcc agctccccac agaagcaaat cactaaagat
      481 caaatctcag cgctcacaga gactcagcat cagcccactt atccgttctg agaaagtctg
      541 tgaggaattg gaaaagttct ttgccagtga caggacaact actaccttca gaaggaggtc
      601 ttcacagtgt tcatcaacac caaggatgag ctctgaactg tccttggatc cagagacttc
      661 tgaaagcagc actcagcaat tctcaggttt cagcacccca gccacctcac agggctgctt
      721 ggattcttca gctgctaaat ccaagatagc tttaaacccc cggaagcaga agaaaaggaa
      781 gtcaacctcc acacctgtga aagtaaagca ggaggagcaa ctccaatcag tgccagccaa
      841 agagaagact acaaccaaga caaaagaagc tgagcaaggg gagcagaaag tggacagtac
      901 agaactatca agccaggagc aaagctccaa aaccgagact caggatacgg cagtagataa
      961 gactccaagt actgatcctg ctttacgact taatccaaga agacgtagaa gaagggccaa
     1021 aaatgagtgg gagatcctag aaagaggcct tctaaagtcc actcaacggt acagcctgaa
     1081 cactaaagct gagtcttcag ctaataaaga gatagctggc aaggagcact ctttcttgaa
     1141 gctgttactg gagaagaaag acatagggca gcctacaact acagaagcag aagttactac
     1201 tgtccagaag atgccatcag ataaagggga tgtggagagg gaattggccg acatagatgt
     1261 tgaagctcaa aaagaaccag caccacaacc tacatctaca gatgtggcag agtccatgat
     1321 tagtggtcca tcaccgcact gtgaagacaa gaagaaaaag gataaagttg gtgtgttgcc
     1381 atggatcaaa aaatctacaa gccaaaaaga ggtcactgtc ttgaggaaag aagaggtcca
     1441 agtgcatgtg catccttctc gagtctgtgg agaaggagag gaagcatcat gtcctgaatt
     1501 gcaaagggtt caaccccaaa tgaaggtatc attggagagc acaacttacc acaaagagaa
     1561 gcatccaaga agtggtctcc cggtcccttc tacaagcatt tcaagtgcta ctgcagaaga
     1621 tgatgtttct ccaaagatga atctgcctct ccctctcaga aggcgaccaa atacagggga
     1681 aacctcctca gattcgaaga gtacctcaga atatgagagt agttctgaaa tgcaactgag
     1741 tcctgcacat tctttcaaac cgacaagaaa gcctaaagat gatgctggtg ctggaactgc
     1801 tgatgatgaa gaagatggag atgatgagaa agaagagaaa gacaatgatg atgatgatga
     1861 agaaaatgtc ttcctcaaat cagaaaatgt agatgtagaa gtgagcaaga tggagaagca
     1921 gcaggctctc agatattctt ctaagttact aggaaaaccc aaagctagag aggcctctgc
     1981 aaaactagag agttcttcag aagatgagag aagttgtgag gaaatgacat ctgcccattc
     2041 ttcccagtcc ttggaagagt ttgaagaatg ctcagaatca agaggtttca tcagaggttc
     2101 catctctgaa gagcggccag caaccaggtg ccattcccag gccttgcagg agttggagga
     2161 aaaggaagtc tccacagaat caagtagtta cattgagaag tacgagagtt ctgaggatct
     2221 gagcagctca gagcaagagc agcaagtgcc tccagtttca aagagttctc taaaacagtg
     2281 gagtgctcct gccaagccag tgcaccccat acaaactgct cagcaacaac ctcccgccat
     2341 ggtgaacatt tctggaggac caaagaaatc tggagagcca ctgtctccca cccagactgt
     2401 caagtcacgg ctgagatctc agtctgagtg tcaagttctt gcagagccag aaggtgttgt
     2461 tgctgctgac tgggacattt taatgcagcc cccacccagg ccaagacttg agcaagaagt
     2521 ttctgcaggt ccagaactta ctgtttttga aaagagtatt gctgtacagc cttctggata
     2581 tcctcctcag ccttcagtga aaccaagcat caagaaagaa atatcgttgg gtgcagaaag
     2641 tgctcccttg gagtccccac ctcctcagca tcattttcag ccactattga agcccttcgt
     2701 aaagcaacag gtatctgctt ttgaaagagt tatttctatg gatccaaagc ttccaacaca
     2761 gttccagcca cggatgaagc ctcaaggaaa gcaatcattt tcttccactc cagagagcac
     2821 agcatttgaa gggagcactt ctgtggacca tatgactctg accctttccc agcctatgct
     2881 acagccttat caagaagtgc ctttagaatc agagactgtt gctgctaaaa tgatttccac
     2941 gggccaacta cattccaaat attctgctca ccccttatca agtcatcaaa gccaaccagt
     3001 cccagaaagc acctctgcag aaggagagga gctgctgcct tctcagcctt cagtgacacc
     3061 caaattccag ccactgatga cccaaggcag tattccttct gcatgggcca ttcctattta
     3121 ttcaccagct cccagaatgg attctaagcc cttgatggga tcagccatcg ctttagagtc
     3181 aaaaccttct aggtactctt tgcagccatg gcagagcacg ccatttgaac aagtgtctgt
     3241 aaccccagat catgatcctg ctgctgctgc cgcttcatgg agccctccta ttgatccacc
     3301 aacttccaga ataccttctc agcccttgat gagattagct gtcaagcaac caacctgtac
     3361 agagttagca agtgtttctg tgtcacagag cagctctctg gaacgactgt cttccagatt
     3421 ccccttccag ccaagagcag atccagagca ctatggagca gaggaaggag ttgctacatt
     3481 gaggagatct agaaggcatc attctcagtc cccagtgaga tcagaattca aggaagaagt
     3541 ttcctcaggt tctcgaagag cttttggaga acggagcatt tctgtgggaa aaatgcctcc
     3601 caaatatgct cttcagccat ggttgtgccc cgaatttcag cagcaagcca aagaggggga
     3661 tgttttgagg aaggcctggc tttcgggaca tccttcccaa accattagta aacataaagt
     3721 cgagaaaaca ccactgcctc ccaaatgtcc cagcccattc ttaaccagat ctaaagttca
     3781 ggaaatatct tcacgtctag agagtgttat tgctcaagag agctccaaga aaccacagag
     3841 aggcaggcca ccttccaagt cctttgtgaa cttcatggca cagcaagtat tttcagagag
     3901 tgctcctagt aaagtggtcc ttcatccaaa gcctgttgct cggggccgaa gacgtccttc
     3961 cagatccctg ttgaagccta aacttgacga ttatgctttc ttatataatt gggataatga
     4021 acccaaggaa gataccacat tgcagaatct gcccatgaag cagccttttc agttatccag
     4081 aaagcctgaa gagccccaag aagttctgcc attttcggag ggtgcccctg tgaagtggaa
     4141 cacttctgcc aggggtatct ctcaggccct ggggaagctc tcagtttctg ttagtcttcc
     4201 gaatgagtgg aagagttctg aaggacagct gccttccaca cagccgtctc aagcctttga
     4261 tgtagctaag ttgcagtcac cggttttacc agtggactca gcaaatgttc ctgtgaagtg
     4321 gagaatttct gagggccatc agcctcctca gtctttcttt gttgactatc agccacaagt
     4381 ttctgtagac tctgccagtg ctgctgctaa aggagccagc tgctggccca tgctgaaaga
     4441 ctcagcttca acaacaaatg tcaaatacag tcaaggctac aaggatttca ctaaaagcac
     4501 cccaacttct gttatcaaac ctgccacgtt cacttctgct cctgcccaga aaccaatggt
     4561 ttccatgggc acttatttta aggatgaggt tcccaagtgt tgtgatgaaa ctggaacttc
     4621 ttcactccta cccaccagca aggctgatgt cgaaaatgtt tttggagtgc ggttgcgaag
     4681 tacctcacag aagattggaa tgaagaatcc ggatccttgc aagccatttg tcctcatttc
     4741 agcagcagca aggaaagaac aagcaaacaa aggagatctc cagggctcag ttggaggctc
     4801 aaagcagtcc agaccagcat ttagctttga gaagaagcaa gggaattggc ccagatatga
     4861 aggcactttg aagaagtcag aagttttcag gcctccagga gagacctcta tttggaaggc
     4921 aaattcccct gtggagccag cttggatcac cacgttaaaa cagcggcaaa ggggctttgt
     4981 atcccaattt tttaaaaaac acaggaccag atctgaaatt agtgtggtga ccaaggattc
     5041 tagatatgag gaatctaaac acataactga tatcccacca aagaagactt ttctttccag
     5101 tttccccgga tgtgcggtgc cacatttaag gcactttcca aaatcagttg cattttatga
     5161 tcagaagatg cttcacccac gtaccaggga aagactaacc agacgatctt tgagtcttcc
     5221 acccacactt ccacaacgtg aggagcctga gtggttttca gtggccaaga agaaagccca
     5281 agcatggagc caaatagcaa atatcatgca ataaatagct cctagatgga gcatcagcat
     5341 tttcagtaat aattgcctgt aactatggta attccatata atattttttg ccagggctag
     5401 tttttattag ggaaaataac tttagaaata ggaattaaca tttttaatta ttcaaatgaa
     5461 ataaatgcta ttaacatcta accctcagta actgaccacc aacatcccca aacccagcat
     5521 gttctccaga aaagctatgt tacagaattg taaaatcatt aactttagat attgtacctt
     5581 taaagaaagg aaacaaccgt attttgcttc agcaacttaa aggttgccat ttctttcaat
     5641 caagtaattt cagtggaaag agtcaggtga tttagctcaa ggattggatg tactttcaac
     5701 caagcaggtg gcaagttcag tagttagact gtgtgtctgc tgcctctgga gagtgacttt
     5761 cctctctggc tccaggctta gggcagagaa ctctgtgtaa ctcagagtct tagttaattt
     5821 ttctattgct gtaataaact ctccgataaa atcaacttaa tggagaaaga gcttattttg
     5881 gaagaattct aatgtatagt ccatcactgc agggaattcc tggcagccag aacttgatga
     5941 agttagttac attgtttttc caggcaagaa atggaaagta atgaattgga gtcctcaact
     6001 tactttctcc ctttaacata cataggccag gatccaagcc taatgaatag tgtcacctat
     6061 ggtgggtggg ttttccccac cttaattaac cttttcattt ttaaattctc cacatttatc
     6121 ctatctctca gtctagcaaa cattataaga aaggcacttt agatgcctta acagcaaacc
     6181 taggatcatt ttcctagata caaaggacat ctacttctgt cacttggtgt ttgctttgct
     6241 tgcacagaaa tacagccttg aacacctatg ttggatgctt ctacattcaa aaccatgtct
     6301 agagaggcaa tgagattcta tagctagctt aaataactgg tgctgggttt ttgctgatga
     6361 tggcataatg agacactgta caacaacatg ctggattttt catttaatct ataaaacacc
     6421 tctttatttt gaccctctag atttgccctt ttgatagtgt taaggttttg aatgactgga
     6481 tttcattcca tatatattac catagtgaat aatttgttta aatcaatgcc cttaacatat
     6541 gtaattctag tacaccagct ctaacacttc ccttccccat ttttgcctat accttcatta
     6601 catcattctc actatgagaa ctccccacta ataatatttc ttccattact aagaaaactc
     6661 agtttttaat cataaggtta agtatttttt taaggttaag tatttttaat gcttagaaat
     6721 atattctgat aagtttcctt ttttcctttt tagctttctt tgtttttgat tagtgctaag
     6781 caaataaact caataaaggt t
//
