LOCUS       NM_001024841            1470 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus predicted gene 128 (Gm128), mRNA.
ACCESSION   NM_001024841
VERSION     NM_001024841.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1470)
  AUTHORS   Yamaguchi,R., Fujihara,Y., Ikawa,M. and Okabe,M.
  TITLE     Mice expressing aberrant sperm-specific protein PMIS2 produce
            normal-looking but fertilization-incompetent spermatozoa
  JOURNAL   Mol Biol Cell 23 (14), 2671-2679 (2012)
   PUBMED   22621904
REFERENCE   2  (bases 1 to 1470)
  AUTHORS   Hlady,R.A., Novakova,S., Opavska,J., Klinkebiel,D., Peters,S.L.,
            Bies,J., Hannah,J., Iqbal,J., Anderson,K.M., Siebler,H.M.,
            Smith,L.M., Greiner,T.C., Bastola,D., Joshi,S., Lockridge,O.,
            Simpson,M.A., Felsher,D.W., Wagner,K.U., Chan,W.C., Christman,J.K.
            and Opavsky,R.
  TITLE     Loss of Dnmt3b function upregulates the tumor modifier Ment and
            accelerates mouse lymphomagenesis
  JOURNAL   J Clin Invest 122 (1), 163-177 (2012)
   PUBMED   22133874
  REMARK    GeneRIF: identify Ment (Gm128) as an enhancer of lymphomagenesis
            that contributes to the tumor suppressor function of Dnmt3b
REFERENCE   3  (bases 1 to 1470)
  AUTHORS   Lin,Q., Donahue,S.L., Moore-Jarrett,T., Cao,S., Osipovich,A.B. and
            Ruley,H.E.
  TITLE     Mutagenesis of diploid mammalian genes by gene entrapment
  JOURNAL   Nucleic Acids Res 34 (20), e139 (2006)
   PUBMED   17062627
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK144488.1.
            
            On Apr 5, 2007 this sequence version replaced NM_001024841.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK144488.1, BC092540.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849378
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1470              AK144488.1         2-1471
FEATURES             Location/Qualifiers
     source          1..1470
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 40.74 cM"
     gene            1..1470
                     /gene="Gm128"
                     /gene_synonym="Ment; pmis1"
                     /note="predicted gene 128"
                     /db_xref="GeneID:229588"
                     /db_xref="MGI:MGI:2684974"
     exon            1..1160
                     /gene="Gm128"
                     /gene_synonym="Ment; pmis1"
                     /inference="alignment:Splign:2.1.0"
     CDS             129..1181
                     /gene="Gm128"
                     /gene_synonym="Ment; pmis1"
                     /note="protein missing in infertile spermatozoa 1;
                     methylated in normal thymocytes protein; protein MENT"
                     /codon_start=1
                     /product="protein MENT precursor"
                     /protein_id="NP_001020012.1"
                     /db_xref="CCDS:CCDS17608.1"
                     /db_xref="GeneID:229588"
                     /db_xref="MGI:MGI:2684974"
                     /translation="MVPAACMLLWALLLSLEYRAAGAEDQTTTPTATTIGMQRVSFRF
                     GGPARSLHSTNPTARTTVPGKLRVTLEDENDALATADRLALPAAAELLSTVTGYSRSS
                     VPSPSDWEEDGSLEEGVVDTRKTTNGPVSLFSTTNTVGSSGTTGRFLANSQEREIKLT
                     TDVRSLSSKTTVVDLSSESTLQQWSTPGSTPSPWLKPSFTAMPSPEDLRVVLMPWGPW
                     HCHCKSGTMSRSRAGKLHGLSGRLRVGALNELRTEHRPCTYQLCACNRHLEECPLDSS
                     LCSDHSCSSRAPFQSSTTSLVPVHLRRRPILPPTSPSPSPALAFWKRVRIGLEDIWNS
                     LSSVFTETQPVERIQR"
     exon            1161..1470
                     /gene="Gm128"
                     /gene_synonym="Ment; pmis1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1258..1263
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gm128"
                     /gene_synonym="Ment; pmis1"
                     /note="hexamer: AATATA"
     polyA_site      1285
                     /gene="Gm128"
                     /gene_synonym="Ment; pmis1"
                     /note="major polyA site"
ORIGIN      
        1 acgtgcctct gagcaccctc ctggtcggtt caaacgacct cgagacctgg cgggttggtg
       61 gagagcggaa gggagggaga gaaggtagga gcctgggcct acctctcgac ctcaagactc
      121 ccagccccat ggtccccgcc gcctgcatgc tgctctgggc cctgctgcta agtctggagt
      181 accgggcggc gggggccgaa gaccaaacga ctaccccgac cgctaccacg attgggatgc
      241 agcgggtcag cttccgcttt gggggcccag cccgcagcct ccacagcaca aaccccaccg
      301 cccggaccac tgtacccggg aagctgaggg taaccctgga ggatgaaaat gatgccctgg
      361 ccactgctga ccgcctggcc ctcccggcag ctgctgagct cctgtccacc gtgacaggct
      421 atagccggtc atcagtgccc agccccagtg actgggagga ggatggctcc ttggaagagg
      481 gggtggttga taccagaaaa accaccaacg gccctgtaag tttattttcg accaccaata
      541 ctgtgggaag ttccggcact accgggaggt ttctagccaa tagccaggag cgagagatta
      601 agctgaccac tgacgtgcgg tccctcagtt caaagactac tgtggtggac ctgtcttctg
      661 agtccaccct gcaacagtgg tcgacacccg ggtccacccc atccccatgg ctaaaaccct
      721 cattcacagc catgccatct cctgaggatc tgcgggtagt actgatgcct tggggccctt
      781 ggcattgcca ctgtaagtca ggcactatga gtaggagccg ggctggaaag ctgcatggcc
      841 tttctgggcg ccttcgagtt ggggcactga atgaactccg cacagaacac cggccttgca
      901 cctaccagtt gtgcgcttgc aacaggcacc tggaggaatg ccctctggac tcgagcctct
      961 gttctgacca tagctgcagc tctcgtgctc cctttcagag cagcaccact tctctggttc
     1021 ctgtccacct gagacgcaga cccatcctgc cacccactag cccgagcccc agcccagctc
     1081 ttgccttttg gaaacgtgtc aggattggcc tggaggatat ctggaacagc ctttcttcag
     1141 tgttcacaga gactcaacca gtagaaagaa tccagaggta atggccatgt ctccctcaag
     1201 agaagatgtc tacattataa actccctttt caaccccaac acccactata tatttttaat
     1261 atatagaaaa aaaagctaaa aaatactttg gtctcatttt tctttttggt ggtgtctggg
     1321 tcaaacctgg ggctccacac atggtggggc ccacggactt ctccccagca cttggctgtg
     1381 tgtttacaga agtgctcagt gacattagag ccagcaggtc tagcctgttc ctttacccct
     1441 ttcttccaaa ataaaatatt cacactgctc
//
