LOCUS       NM_145935               1310 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus glycine-N-acyltransferase (Glyat), mRNA.
ACCESSION   NM_145935
VERSION     NM_145935.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1310)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1310)
  AUTHORS   Dempsey,D.R., Bond,J.D., Carpenter,A.M., Rodriguez Ospina,S. and
            Merkler,D.J.
  TITLE     Expression, purification, and characterization of mouse glycine
            N-acyltransferase in Escherichia coli
  JOURNAL   Protein Expr Purif 97, 23-28 (2014)
   PUBMED   24576660
  REMARK    GeneRIF: Mouse glycine N-acyltransferase was successfully
            overexpressed and purified from Escherichia coli. Benzoyl-CoA and
            glycine were the substrates with the highest (kcat/Km)app values.
REFERENCE   3  (bases 1 to 1310)
  AUTHORS   Kim,S.C., Sprung,R., Chen,Y., Xu,Y., Ball,H., Pei,J., Cheng,T.,
            Kho,Y., Xiao,H., Xiao,L., Grishin,N.V., White,M., Yang,X.J. and
            Zhao,Y.
  TITLE     Substrate and functional diversity of lysine acetylation revealed
            by a proteomics survey
  JOURNAL   Mol Cell 23 (4), 607-618 (2006)
   PUBMED   16916647
REFERENCE   4  (bases 1 to 1310)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK039262.1.
            
            On Apr 5, 2007 this sequence version replaced NM_145935.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK039262.1, AK143803.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849385, SAMN00849386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1310              AK039262.1         2-1311
FEATURES             Location/Qualifiers
     source          1..1310
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 8.73 cM"
     gene            1..1310
                     /gene="Glyat"
                     /gene_synonym="A330009E03Rik; ACGNAT; CAT; GAT"
                     /note="glycine-N-acyltransferase"
                     /db_xref="GeneID:107146"
                     /db_xref="MGI:MGI:2147502"
     exon            1..299
                     /gene="Glyat"
                     /gene_synonym="A330009E03Rik; ACGNAT; CAT; GAT"
                     /inference="alignment:Splign:2.1.0"
     exon            300..394
                     /gene="Glyat"
                     /gene_synonym="A330009E03Rik; ACGNAT; CAT; GAT"
                     /inference="alignment:Splign:2.1.0"
     CDS             314..1204
                     /gene="Glyat"
                     /gene_synonym="A330009E03Rik; ACGNAT; CAT; GAT"
                     /EC_number="2.3.1.13"
                     /EC_number="2.3.1.71"
                     /note="AAc; acyl-CoA:glycine N-acyltransferase; aralkyl
                     acyl-CoA N-acyltransferase; aralkyl acyl-CoA:amino acid
                     N-acyltransferase; glycine N-benzoyltransferase;
                     benzoyl-coenzyme A:glycine N-acyltransferase"
                     /codon_start=1
                     /product="glycine N-acyltransferase"
                     /protein_id="NP_666047.1"
                     /db_xref="CCDS:CCDS29633.1"
                     /db_xref="GeneID:107146"
                     /db_xref="MGI:MGI:2147502"
                     /translation="MIVPLQGAQMLQMLEKSLRKYLPESLKVYGTVYHMIHGNPFNLK
                     ALVDKWPDFNTVVVRPQEQEMTDDLDFYINTYQVYSKDPQNCQEFLESSEVINWKQHL
                     QIQSSQSHLNKTIQNLASIQSFQIKHSENILYVSSETIKKLFPSLLDTKNLSTGSGKP
                     KAIDQDKFKLSSLDVVHAALVNKFWLFGGNERSQRFIERCIKNFPSSCVLGPEGTPAS
                     WTLMDQTGEMRMGGTMPEYRLQGLVSFVVHSQDQIMTKRGYPVYSHTEKSNIAMQKMS
                     YTLQHLPMPCAWNQWKCMPM"
     exon            395..502
                     /gene="Glyat"
                     /gene_synonym="A330009E03Rik; ACGNAT; CAT; GAT"
                     /inference="alignment:Splign:2.1.0"
     exon            503..629
                     /gene="Glyat"
                     /gene_synonym="A330009E03Rik; ACGNAT; CAT; GAT"
                     /inference="alignment:Splign:2.1.0"
     exon            630..801
                     /gene="Glyat"
                     /gene_synonym="A330009E03Rik; ACGNAT; CAT; GAT"
                     /inference="alignment:Splign:2.1.0"
     exon            802..1310
                     /gene="Glyat"
                     /gene_synonym="A330009E03Rik; ACGNAT; CAT; GAT"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1310
                     /gene="Glyat"
                     /gene_synonym="A330009E03Rik; ACGNAT; CAT; GAT"
                     /note="putative"
ORIGIN      
        1 aaagtgatat ttagaagaga gtagttcaga aggcaaatgt cagcctcatc ttgcagagcc
       61 gattcctaca gcatgagatc agcaaaggag ggaagagtta gatttctgga gacctgacaa
      121 gctgaagatt ttgtcaacgg gcttagagca aagtccacat tttctgcctc agttcagtta
      181 atttctgaaa gagattcacc aaagctcact cactcttccg gttctcacca agcctgctgt
      241 atcagacttt catctctcag aagtccattt ttacgaagat tgctgagaca gctttccagg
      301 ctaaagtgtc ctcatgattg ttccattaca aggtgcacag atgctacaaa tgttggagaa
      361 atccttgagg aagtaccttc ctgaatcctt aaaggtttat gggaccgtct atcacatgat
      421 ccatggaaac ccattcaacc taaaagccct agttgacaag tggcctgatt ttaacacagt
      481 ggttgtccgc cctcaagaac aggagatgac agatgacctt gatttctaca tcaatactta
      541 ccaggtctac tccaaagacc cccagaactg tcaggaattc ctggagtcct cagaagtcat
      601 taactggaaa caacatttgc agattcaaag ttcccagtcc cacctgaata agacgataca
      661 aaatcttgca agcatccaat cttttcaaat caaacattca gaaaacatcc tctatgtatc
      721 atcagagaca atcaagaaac tgttcccttc cctgctggat acaaagaatt tatcgacagg
      781 aagtggcaag cccaaggcca ttgatcaaga caagtttaaa ctttcatcct tggatgttgt
      841 ccatgctgcc ttggtgaata aattctggct ttttggtggc aatgagagga gccagagatt
      901 cattgaacgc tgcataaaga acttcccaag ttcctgtgtc ctggggcctg agggaacccc
      961 tgcatcttgg actctaatgg accaaactgg agagatgcga atgggaggca ctatgcctga
     1021 gtaccggctc caaggtcttg tctcctttgt tgtccattca caagaccaga ttatgacaaa
     1081 gcgtggttat cctgtttatt ctcacacgga gaaaagtaat atcgctatgc aaaaaatgag
     1141 ttacacactg cagcatctcc ccatgccctg tgcctggaac caatggaagt gcatgcctat
     1201 gtgaagctgg actcaaacag aagctggtgt tgagtgggcc cagggatgta actggtggtg
     1261 gacaaagagt gaagattact gaaaagatag aataaatggc aactagctgc
//
