LOCUS       NM_026223               1879 bp    mRNA    linear   ROD 31-MAY-2024
DEFINITION  Mus musculus GLI pathogenesis-related 1 like 2 (Glipr1l2),
            transcript variant 1, mRNA.
ACCESSION   NM_026223 XM_916007
VERSION     NM_026223.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1879)
  AUTHORS   Kise,Y., Takenaka,K., Tezuka,T., Yamamoto,T. and Miki,H.
  TITLE     Fused kinase is stabilized by Cdc37/Hsp90 and enhances Gli protein
            levels
  JOURNAL   Biochem Biophys Res Commun 351 (1), 78-84 (2006)
   PUBMED   17054904
  REMARK    GeneRIF: This growth inhibition is partially rescued by expression
            of ectopic Gli1, suggesting that Fu may contribute to enhance Hh
            signaling activity in cancer cells.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK014846.1.
            
            On Apr 5, 2007 this sequence version replaced NM_026223.1.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK014846.1, AK161292.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1879              AK014846.1         2-1880
FEATURES             Location/Qualifiers
     source          1..1879
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 60.09 cM"
     gene            1..1879
                     /gene="Glipr1l2"
                     /gene_synonym="4921508O11Rik"
                     /note="GLI pathogenesis-related 1 like 2"
                     /db_xref="GeneID:67537"
                     /db_xref="MGI:MGI:1914787"
     exon            1..247
                     /gene="Glipr1l2"
                     /gene_synonym="4921508O11Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             23..1021
                     /gene="Glipr1l2"
                     /gene_synonym="4921508O11Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     GLIPR1-like protein 2"
                     /codon_start=1
                     /product="GLIPR1-like protein 2 isoform 1"
                     /protein_id="NP_080499.1"
                     /db_xref="CCDS:CCDS24171.1"
                     /db_xref="GeneID:67537"
                     /db_xref="MGI:MGI:1914787"
                     /translation="MKASLPWSVVWRAQSNYVRLRRVLKLCELWLLLVGSGLNAKLPL
                     EEDVDFINEYVGLHNELRGTVFPPGVNLRFMTWDVALSRTARAWGKKCMYSRNTHLDK
                     LHESHPVFTEIGENMWVGPVEDFTVTTAIRSWHEERKSYSYLNDTCVEDQNCSHYIQL
                     VWDSSYKVGCAVTSCARAGGFTHAALFICNYAPGGTLTRRPYQAGQFCSRCGPGDQCT
                     DYLCSNTVRDEATYYQFWYPPWEKPRPVVCNPMCIFILFLRVASLLLCVIVVLIVQSR
                     FPVILMETPTIISAEEEGKTEVEIVMEEGEGEGEGGEGEGEGEEKEEEEMLEEDEQ"
     exon            248..499
                     /gene="Glipr1l2"
                     /gene_synonym="4921508O11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            500..603
                     /gene="Glipr1l2"
                     /gene_synonym="4921508O11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            604..689
                     /gene="Glipr1l2"
                     /gene_synonym="4921508O11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            690..716
                     /gene="Glipr1l2"
                     /gene_synonym="4921508O11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            717..1879
                     /gene="Glipr1l2"
                     /gene_synonym="4921508O11Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1764..1769
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Glipr1l2"
                     /gene_synonym="4921508O11Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1784
                     /gene="Glipr1l2"
                     /gene_synonym="4921508O11Rik"
                     /note="major polyA site"
ORIGIN      
        1 actggcttgt ccgccggtga ccatgaaggc ctctctgcct tggtctgtag tatggcgtgc
       61 ccagtcgaat tacgtacggc taagaagagt actgaagctg tgtgaactgt ggcttctatt
      121 ggtgggctca ggtttgaacg ccaaacttcc gcttgaagag gatgtagact ttatcaatga
      181 atatgtgggt ctccataatg agcttcgagg cacggtcttc cccccagggg tgaacctgcg
      241 cttcatgact tgggatgtag ctttatcgcg tactgccaga gcatggggga aaaaatgtat
      301 gtatagccgt aatactcatc tagacaaact ccatgaatcc catccagtat ttactgaaat
      361 tggcgaaaac atgtgggttg gtcctgtaga ggactttact gtaaccactg ccatcagaag
      421 ttggcatgag gagaggaaga gctacagtta cttaaatgac acttgtgttg aggaccagaa
      481 ctgttctcat tacattcagc ttgtgtggga cagttcctac aaagttggtt gtgctgttac
      541 ttcgtgtgca agggctggag gtttcacaca cgcagcactt ttcatatgca attatgcacc
      601 aggaggaacc ctgacaagga ggccttatca agcagggcaa ttttgttctc ggtgtggccc
      661 tggagaccaa tgcacagact acctatgcag taacacagtt cgtgatgaag ctacatacta
      721 ccagttctgg tacccacctt gggaaaagcc ccgcccagtc gtgtgtaatc caatgtgcat
      781 atttatcctc ttcctgagag tggcatcttt gctgctatgt gtcattgtcg ttctgatagt
      841 tcagtccagg tttccagtta tcttaatgga aactccaacg ataatttcag cagaggagga
      901 agggaaaact gaggtagaaa tagtgatgga ggagggagag ggagagggag agggaggaga
      961 gggagaggga gagggagagg aaaaggaaga ggaagagatg ctggaagaag atgaacaata
     1021 ggaagaagat aaccccagag gaaggagagg aagagatgca ggaagaagac aactcaatag
     1081 aagccaaagc ccaacaggaa aaaaaaatcc caaaacgtta aaaggtagaa tgctgaactt
     1141 taaaaacaaa atatgcaaac ctcaattata tttttcattc cttttctata attatttaac
     1201 aaatttacat tggaaaaaaa acagtgtgaa tgcaaggctt gcattgtaca gaaaatatta
     1261 agctcttaaa gacacagaga atggataata ggagcagcaa catcagcaaa aagatgcctt
     1321 aaaattttat tatggtatct gataaaaaca agaaataatt catatttcta tctctgtgta
     1381 gagttttttt tatatgagtt taaaagtatc tgaagtatta agttaaatga aattgtccat
     1441 ataagacact aaggaccact ctgagtttag aatagccatt tgataaatat taactcattt
     1501 ttattattac tattatagtt gtcggtagtg gttgtatttt acatgtgata tcaaaacatc
     1561 aaatgttttt ttatatttta tgtatacttg taaaatagtt tactcaatac tattcccttg
     1621 tgttagaaga tttataaatg tataatttct actccacggc cagtaattca tcagactttc
     1681 tctaatattt gtcaagtagg tccaagaaat gaaaaacaat cactcattgt aagtaagcaa
     1741 tatagctgct tctacattta tataataaag tagatttcac gttactcagt atgtacagta
     1801 gaatttgtgg ggaaaataag ttgacatatg aatagtaata ttgattaatt cattgaataa
     1861 aatgttagcc tggcaaaat
//
