LOCUS       NM_027018                899 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Mus musculus GLI pathogenesis-related 1 like 1 (Glipr1l1), mRNA.
ACCESSION   NM_027018 XM_916000 XM_993553
VERSION     NM_027018.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 899)
  AUTHORS   Gaikwad,A.S., Anderson,A.L., Merriner,D.J., O'Connor,A.E.,
            Houston,B.J., Aitken,R.J., O'Bryan,M.K. and Nixon,B.
  TITLE     GLIPR1L1 is an IZUMO-binding protein required for optimal
            fertilization in the mouse
  JOURNAL   BMC Biol 17 (1), 86 (2019)
   PUBMED   31672133
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 899)
  AUTHORS   Tang,T., Li,L., Tang,J., Li,Y., Lin,W.Y., Martin,F., Grant,D.,
            Solloway,M., Parker,L., Ye,W., Forrest,W., Ghilardi,N., Oravecz,T.,
            Platt,K.A., Rice,D.S., Hansen,G.M., Abuin,A., Eberhart,D.E.,
            Godowski,P., Holt,K.H., Peterson,A., Zambrowicz,B.P. and de
            Sauvage,F.J.
  TITLE     A mouse knockout library for secreted and transmembrane proteins
  JOURNAL   Nat Biotechnol 28 (7), 749-755 (2010)
   PUBMED   20562862
REFERENCE   3  (bases 1 to 899)
  AUTHORS   Gibbs,G.M., Lo,J.C., Nixon,B., Jamsai,D., O'Connor,A.E., Rijal,S.,
            Sanchez-Partida,L.G., Hearn,M.T., Bianco,D.M. and O'Bryan,M.K.
  TITLE     Glioma pathogenesis-related 1-like 1 is testis enriched,
            dynamically modified, and redistributed during male germ cell
            maturation and has a potential role in sperm-oocyte binding
  JOURNAL   Endocrinology 151 (5), 2331-2342 (2010)
   PUBMED   20219979
  REMARK    GeneRIF: Zona pellucida binding assays indicate that GLIPR1L1 has a
            role in the binding of sperm to the zona pellucida surrounding the
            oocyte.
REFERENCE   4  (bases 1 to 899)
  AUTHORS   Godambe,S.A., Chaplin,D.D. and Bellone,C.J.
  TITLE     Regulation of IL-1 gene expression: differential responsiveness of
            murine macrophage lines
  JOURNAL   Cytokine 5 (4), 327-335 (1993)
   PUBMED   8260598
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK005860.1 and BX635028.1.
            
            On or before Apr 11, 2009 this sequence version replaced
            XM_916000.2, XM_993553.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK005860.1, CF106136.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-892               AK005860.1         2-893
            893-899             BX635028.1         1-7                 c
FEATURES             Location/Qualifiers
     source          1..899
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 60.07 cM"
     gene            1..899
                     /gene="Glipr1l1"
                     /gene_synonym="1700011E04Rik"
                     /note="GLI pathogenesis-related 1 like 1"
                     /db_xref="GeneID:69286"
                     /db_xref="MGI:MGI:1916536"
     exon            1..319
                     /gene="Glipr1l1"
                     /gene_synonym="1700011E04Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             122..832
                     /gene="Glipr1l1"
                     /gene_synonym="1700011E04Rik"
                     /note="GLIPR1-like protein 1"
                     /codon_start=1
                     /product="GLIPR1-like protein 1 precursor"
                     /protein_id="NP_081294.1"
                     /db_xref="CCDS:CCDS48691.1"
                     /db_xref="GeneID:69286"
                     /db_xref="MGI:MGI:1916536"
                     /translation="MALKKKLNFLWTLVLYLIASRLPKAFGKDLPRVPTITDPKFIDA
                     FLNIHNELRRKVQPPAADMNQLFWDQQLAKLAKAWTRECKLAHNPCIKQRYECLEDYD
                     FIGENIYLGRIETQPEDVVINWYNESKYFNFDFNTCSEMCGHYTQVVWAKTVKIGCAV
                     SNCPNLKGFSAGLFVCNYSPAGNFIGFRPYTRGDSCSMCGQKTCENSLCRPMNRKTPH
                     HKAACHVLVLGFILQSLL"
     exon            320..562
                     /gene="Glipr1l1"
                     /gene_synonym="1700011E04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            563..663
                     /gene="Glipr1l1"
                     /gene_synonym="1700011E04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            664..749
                     /gene="Glipr1l1"
                     /gene_synonym="1700011E04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            750..896
                     /gene="Glipr1l1"
                     /gene_synonym="1700011E04Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      872..877
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Glipr1l1"
                     /gene_synonym="1700011E04Rik"
                     /note="hexamer: AATAAA"
     polyA_site      896
                     /gene="Glipr1l1"
                     /gene_synonym="1700011E04Rik"
                     /note="major polyA site"
ORIGIN      
        1 agtctccatg gcaacactgg ctgccttgaa cacattcccc aggctaatgg gaagacagag
       61 ccagtttaaa gtgtaatctc tgttcttgca cattcactag gggtatccac gacatccttc
      121 catggccctg aagaagaaac ttaatttttt atggacatta gttctgtatt tgatagccag
      181 cagactgccc aaggcattcg gcaaagatct tcctagggtg ccaactatca cggatccgaa
      241 atttatagat gcattcctca acatccacaa tgaactgcga cgcaaggtcc agcccccggc
      301 agctgatatg aatcaactgt tttgggacca gcagctggca aaactagcga aagcatggac
      361 tagagagtgc aaacttgccc ataatccctg tatcaaacaa cgatacgaat gtcttgagga
      421 ctatgacttt attggagaaa atatttattt gggtagaatt gaaacccaac cagaagatgt
      481 tgttattaat tggtataatg aaagtaaata ttttaatttt gattttaata cctgttctga
      541 aatgtgtggc cattatacac aggtagtttg ggccaaaacg gttaaaattg gttgtgcagt
      601 ttcaaattgt cctaatctca agggcttttc agctgggcta tttgtatgta attattcgcc
      661 agcaggaaac tttataggct tcagacctta cacgagagga gactcttgct ctatgtgtgg
      721 acaaaagacg tgtgagaata gtctctgccg tcccatgaat cggaagacac ctcaccacaa
      781 agcggcatgc catgtacttg tgcttggttt tattcttcag agcctacttt aactgttatt
      841 tctattcaga agaaaaattt tgaatgctaa aaataaaaga cttatttttc tgactaaaa
//
