LOCUS       NM_133236               6201 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus glucocorticoid induced transcript 1 (Glcci1),
            transcript variant 1, mRNA.
ACCESSION   NM_133236 NM_178072
VERSION     NM_133236.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6201)
  AUTHORS   Takada,M., Fukuhara,D., Takiura,T., Nishibori,Y., Kotani,M.,
            Kiuchi,Z., Kudo,A., Beltcheva,O., Ito-Nitta,N., Nitta,K.R.,
            Kimura,T., Suehiro,J.I., Katada,T., Takematsu,H. and Yan,K.
  TITLE     Involvement of GLCCI1 in mouse spermatogenesis
  JOURNAL   FASEB J 37 (1), e22680 (2023)
   PUBMED   36468710
REFERENCE   2  (bases 1 to 6201)
  AUTHORS   Xun,Q., Kuang,J., Yang,Q., Wang,W. and Zhu,G.
  TITLE     Glucocorticoid induced transcript 1 represses airway remodeling of
            asthmatic mouse via inhibiting IL-13/periostin/TGF-beta1 signaling
  JOURNAL   Int Immunopharmacol 97, 107637 (2021)
   PUBMED   33895479
  REMARK    GeneRIF: Glucocorticoid induced transcript 1 represses airway
            remodeling of asthmatic mouse via inhibiting
            IL-13/periostin/TGF-beta1 signaling.
REFERENCE   3  (bases 1 to 6201)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6201)
  AUTHORS   Xun,Q., Kuang,J., Yang,Q., Wang,W. and Zhu,G.
  TITLE     GLCCI1 reduces collagen deposition and airway hyper-responsiveness
            in a mouse asthma model through binding with WD repeat domain 45B
  JOURNAL   J Cell Mol Med 25 (14), 6573-6583 (2021)
   PUBMED   34050597
  REMARK    GeneRIF: GLCCI1 reduces collagen deposition and airway
            hyper-responsiveness in a mouse asthma model through binding with
            WD repeat domain 45B.
REFERENCE   5  (bases 1 to 6201)
  AUTHORS   Mayer,C., Hafemeister,C., Bandler,R.C., Machold,R., Batista
            Brito,R., Jaglin,X., Allaway,K., Butler,A., Fishell,G. and
            Satija,R.
  TITLE     Developmental diversification of cortical inhibitory interneurons
  JOURNAL   Nature 555 (7697), 457-462 (2018)
   PUBMED   29513653
REFERENCE   6  (bases 1 to 6201)
  AUTHORS   Sharov,A.A., Piao,Y., Matoba,R., Dudekula,D.B., Qian,Y.,
            VanBuren,V., Falco,G., Martin,P.R., Stagg,C.A., Bassey,U.C.,
            Wang,Y., Carter,M.G., Hamatani,T., Aiba,K., Akutsu,H., Sharova,L.,
            Tanaka,T.S., Kimber,W.L., Yoshikawa,T., Jaradat,S.A., Pantano,S.,
            Nagaraja,R., Boheler,K.R., Taub,D., Hodes,R.J., Longo,D.L.,
            Schlessinger,D., Keller,J., Klotz,E., Kelsoe,G., Umezawa,A.,
            Vescovi,A.L., Rossant,J., Kunath,T., Hogan,B.L., Curci,A.,
            D'Urso,M., Kelso,J., Hide,W. and Ko,M.S.
  TITLE     Transcriptome analysis of mouse stem cells and early embryos
  JOURNAL   PLoS Biol 1 (3), E74 (2003)
   PUBMED   14691545
REFERENCE   7  (bases 1 to 6201)
  AUTHORS   Miazek,A. and Malissen,B.
  TITLE     Two genes, three messengers: hybrid transcript between a gene
            expressed at specific stages of T-cell and sperm maturation and an
            unrelated adjacent gene
  JOURNAL   Immunogenetics 54 (10), 681-692 (2003)
   PUBMED   12557054
REFERENCE   8  (bases 1 to 6201)
  AUTHORS   Suzuki,H., Fukunishi,Y., Kagawa,I., Saito,R., Oda,H., Endo,T.,
            Kondo,S., Bono,H., Okazaki,Y. and Hayashizaki,Y.
  TITLE     Protein-protein interaction panel using mouse full-length cDNAs
  JOURNAL   Genome Res 11 (10), 1758-1765 (2001)
   PUBMED   11591653
REFERENCE   9  (bases 1 to 6201)
  AUTHORS   Chapman,M.S., Askew,D.J., Kuscuoglu,U. and Miesfeld,R.L.
  TITLE     Transcriptional control of steroid-regulated apoptosis in murine
            thymoma cells
  JOURNAL   Mol Endocrinol 10 (8), 967-978 (1996)
   PUBMED   8843413
REFERENCE   10 (bases 1 to 6201)
  AUTHORS   Chapman,M.S., Qu,N., Pascoe,S., Chen,W.X., Apostol,C., Gordon,D.
            and Miesfeld,R.L.
  TITLE     Isolation of differentially expressed sequence tags from
            steroid-responsive cells using mRNA differential display
  JOURNAL   Mol Cell Endocrinol 108 (1-2), R1-R7 (1995)
   PUBMED   7758820
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC156290.10, CN720421.1, DV652660.1, BG081330.2, AK037672.1,
            AY098636.1 and AV355078.1.
            
            On Nov 14, 2013 this sequence version replaced NM_133236.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            CCDS Note: The coding region has been updated to represent an
            alternative 5' splice pattern, resulting in a longer and distinct
            N-terminus that is better supported by available transcript and
            homology data.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY098636.1, SRR7652917.846367.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849377
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-643               AC156290.10        30902-31544
            644-1177            CN720421.1         1-534
            1178-1557           DV652660.1         77-456
            1558-2103           BG081330.2         31-576
            2104-2723           AK037672.1         190-809
            2724-5936           AK037672.1         811-4023
            5937-6200           AY098636.1         5978-6241
            6201-6201           AV355078.1         247-247
FEATURES             Location/Qualifiers
     source          1..6201
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 4.38 cM"
     gene            1..6201
                     /gene="Glcci1"
                     /gene_synonym="2310047L21Rik; A130036A18Rik; Fam117c;
                     Gig18; Tssn1"
                     /note="glucocorticoid induced transcript 1"
                     /db_xref="GeneID:170772"
                     /db_xref="MGI:MGI:2179717"
     exon            1..720
                     /gene="Glcci1"
                     /gene_synonym="2310047L21Rik; A130036A18Rik; Fam117c;
                     Gig18; Tssn1"
                     /inference="alignment:Splign:2.1.0"
     CDS             288..1904
                     /gene="Glcci1"
                     /gene_synonym="2310047L21Rik; A130036A18Rik; Fam117c;
                     Gig18; Tssn1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     glucocorticoid-induced transcript 1 protein; testhymin;
                     glucocorticoid-induced gene 18 protein;
                     thymocyte/spermatocyte selection protein 1"
                     /codon_start=1
                     /product="glucocorticoid-induced transcript 1 protein
                     isoform 1"
                     /protein_id="NP_573499.2"
                     /db_xref="CCDS:CCDS19910.2"
                     /db_xref="GeneID:170772"
                     /db_xref="MGI:MGI:2179717"
                     /translation="MSTASSSSSQTPHSAPQRMRRSTAGSPPAAAGSGTGPAGSCAPA
                     AGAGRLLQPIRATVPYQLLRGSQHSPTRPAAAAATAAAALGSLSGPGGARGPSPSSPT
                     PPPAAAPAEQAPRAKGRPRRSPESRRRSSSPERRSPGSPVCRVDRPKSQHIRTSSTIR
                     RTSSLDTITGPYLTGQWPRDPHVHYPSCMRDKATQTPSCWAEEGAEKRSHQRSASWGS
                     ADQLKEIAKLRQQLQRSKQSSRHSKEKDRQSPLHGNHITISHTQAIGSRSVPMPLSNI
                     SVPKSSVSRVPCNVEGISPELEKVFIKENNGKEEVSKPLDIPDGRRAPLPAHYRSSST
                     RSIDTQTPSVQERSSSCSSHSPCVSPFCPPESQDGSPCSTEDLLYDRDKDSGSSSPLP
                     KYASSPKPNNSYMFKREPPEGCERVKVFEEMASRQPISAPLFSCPDKNKVNFIPTGSA
                     FCPVKLLGPLLPASDLMLKNSPNSGQSSALATLTVEQLSSRVSFTSLSDDTSTADSLE
                     PSAQQPSQQQQLLQDLQVEEHVSTQNYVMI"
     exon            721..872
                     /gene="Glcci1"
                     /gene_synonym="2310047L21Rik; A130036A18Rik; Fam117c;
                     Gig18; Tssn1"
                     /inference="alignment:Splign:2.1.0"
     exon            873..959
                     /gene="Glcci1"
                     /gene_synonym="2310047L21Rik; A130036A18Rik; Fam117c;
                     Gig18; Tssn1"
                     /inference="alignment:Splign:2.1.0"
     exon            960..1073
                     /gene="Glcci1"
                     /gene_synonym="2310047L21Rik; A130036A18Rik; Fam117c;
                     Gig18; Tssn1"
                     /inference="alignment:Splign:2.1.0"
     exon            1074..1226
                     /gene="Glcci1"
                     /gene_synonym="2310047L21Rik; A130036A18Rik; Fam117c;
                     Gig18; Tssn1"
                     /inference="alignment:Splign:2.1.0"
     exon            1227..1437
                     /gene="Glcci1"
                     /gene_synonym="2310047L21Rik; A130036A18Rik; Fam117c;
                     Gig18; Tssn1"
                     /inference="alignment:Splign:2.1.0"
     exon            1438..1558
                     /gene="Glcci1"
                     /gene_synonym="2310047L21Rik; A130036A18Rik; Fam117c;
                     Gig18; Tssn1"
                     /inference="alignment:Splign:2.1.0"
     exon            1559..6201
                     /gene="Glcci1"
                     /gene_synonym="2310047L21Rik; A130036A18Rik; Fam117c;
                     Gig18; Tssn1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6176..6181
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Glcci1"
                     /gene_synonym="2310047L21Rik; A130036A18Rik; Fam117c;
                     Gig18; Tssn1"
                     /note="hexamer: AATAAA"
     polyA_site      6200
                     /gene="Glcci1"
                     /gene_synonym="2310047L21Rik; A130036A18Rik; Fam117c;
                     Gig18; Tssn1"
                     /note="major polyA site"
ORIGIN      
        1 cgggcgagtg ccctgtcagc gcgatgcccg gggcggcggc ggcggcggcc atgggctcga
       61 cgcgggctct gccgtgagcg ccccgcagag cgccgcgggg cggttgagcc gttggacgtt
      121 ggccgtcgcg gcgtcccctc cccctcggcg gcggggtgcg cgtcggaagg ggagccccgc
      181 ggctccgccc ctccccgccc ctcccccgta cacatcgcac gcaccgcggc gccggctccc
      241 acacgctcgc tcgcgcgccc gcccgcccgc ccgcccgcgg agccaccatg tccactgcgt
      301 cctccagttc ctctcagacc cctcactccg cgccgcagag gatgcggcgc agcaccgcgg
      361 gctccccgcc cgccgctgcc gggagcggga cggggccggc cgggagctgc gcaccggctg
      421 cgggagccgg tcggctgctg cagcccatcc gcgccacggt gccctaccag ctcctgcggg
      481 gcagccagca cagccccacg cgcccggccg ccgccgccgc caccgccgcc gccgcgctcg
      541 gcagtctctc cgggcccgga ggggcccgcg gccccagccc gtccagcccg actccaccgc
      601 cggccgctgc cccagccgag caggcgcctc gcgccaaggg ccgcccgaga cggtcccccg
      661 agagccggcg gaggagcagc tcacctgaga gacggagtcc cggctcgccc gtgtgcagag
      721 tggacaggcc aaaatctcaa catattcgaa cctctagtac aataaggcga acctcttctc
      781 tggatacgat aacaggacct tacctcacag gacagtggcc acgggaccct catgttcact
      841 acccttcatg catgagagat aaagccactc agacacctag ttgctgggca gaagagggag
      901 cagaaaaacg atcacatcag cgctctgcat catggggaag tgctgatcaa ctgaaagaga
      961 ttgccaaact taggcaacag ctacaacgca gcaagcaaag tagtcggcat agtaaagaga
     1021 aggacagaca gtcacctctc catggcaacc acataacaat cagtcatact caggctattg
     1081 gatcaagatc agtccctatg cctctgtcaa acatatcagt gccaaaatca tctgtttccc
     1141 gtgtaccctg caatgtagaa ggaataagtc ctgaattgga aaaggtattc atcaaagaaa
     1201 acaatggaaa ggaagaagtg tccaagccat tggatatacc agatggtcga agagctccgc
     1261 tccctgctca ctacaggagc agtagtactc gaagcataga tacccagaca ccttctgtcc
     1321 aagagcgcag cagtagctgc agcagccact ccccttgtgt gtccccattt tgtcctccgg
     1381 aatcccagga tggaagtcct tgttcaacag aagatttgct ctatgatcgt gataaagaca
     1441 gtgggagtag ctcaccgtta cccaagtatg cttcatctcc caaacccaac aacagctaca
     1501 tgttcaaacg ggagccccca gagggatgtg agcgggtgaa ggtctttgag gaaatggcgt
     1561 ctcgtcagcc tatctcggcc cctctctttt catgtcctga caaaaacaag gttaatttca
     1621 tcccaaccgg atcagctttc tgtcctgtaa aacttctagg ccctctctta cctgcctctg
     1681 acctgatgct caagaactcc cctaattctg gccagagctc ggctctggca acactgaccg
     1741 tagagcagct ttcctcccgg gtttccttca catctctctc tgatgacacc agcacagccg
     1801 actccctgga gccctctgcc cagcagccat ctcagcagca gcagctccta caggacttgc
     1861 aggtggagga acacgtctcc actcagaact atgtgatgat ctaaagcaga gggggagctg
     1921 gtctccaccc atggtccatg gattgggaat gagatctcag acatctatct gcatggagtg
     1981 acaaactttc ccaacatcac caacagcaaa gtacttagca tcacaaaata gctattaaca
     2041 ctgatcttgg cagggaccga cttatattca gcagtttttg tggaaagcag taatgcttgc
     2101 aaaaatgtgt gtgtcattca gcatttaatg gagactatgc atttcatagt atgtctgaca
     2161 gattagtact gtgtcctgtg ttttgttcca acattttcag tatgaataag ctctatttca
     2221 aaaagttgcc tgtctaagta gaaaatgtct tgctgtgttt tgtcctatgg aaaatactgt
     2281 acttcaggat tatgtttaca attgatccag gtgtttgttt ctaacttcta taatacatac
     2341 aatgcaaaaa aaaaaaaaaa atggccacaa cagttgcaca gtgcccaccc tatggcctag
     2401 cttcaggtac ttcagttgaa gtctaaactc aggtaacttg gaatgtatgt catattggga
     2461 tattaaatat ttcacagcta caaagctaaa gagggaacat cactcttttg cctttccttg
     2521 ttttatgcat ttccttttct tcattccatt ccacactaga ataagaagtg cattgatccc
     2581 taggagatgc taatcctggg tatagggaac atgaggagaa ccagcaaatt tgtggtgtgt
     2641 gacatcactt ttgtcatgtg gttaccagta gaacaactgt tgcattcact gtttcaacat
     2701 gtgtaaatgt ggcttttttt tttaaaaaaa aagaaaaaga aaaaagaaaa aacaagttgt
     2761 gttgctcagt gactgactgt tacagtgttg caaataaagc ctcagtagta gcctacataa
     2821 acattcccca ttgcgtgtga cgaaatttaa atgcagggat ggctggagtt catttcaaag
     2881 caagtggcgt tttgcagaaa taaataagga tttttcttta tattggccat tggggtcata
     2941 attgctacta tttttatcta aagacatatt tatgtttagc ttcattttag gaaattgtaa
     3001 ttttctggtt acaaagtgaa acattttggt tactgttttc ctcaagtatt tggtaaatga
     3061 gttgtattca tgtagagaga atgtgtatgt ctcagaacca gtgcagcata agcaagcaga
     3121 tttcttgttg actttcgaga gcaatagctt aaagctgtct catttaagcc tcagataaca
     3181 ctatcatgaa taattttgtt aagacgtaga acgcatggag tggagcagaa ccccgagtaa
     3241 atagccttga acttgcagac ttgacagaag ttctccacaa agtgcataga agagagccat
     3301 agagattcct gttgccacct ggagagcccg acttcagact ttattttttt gcagcacagc
     3361 ctgtgcaaaa gtaaagggac gcttttgtat tggtgttccg ttgctctcag ttcagttaga
     3421 gcctagagtt ctcccatctc cacctaacgt gtgtggcaca atgtttggtt tggttggttt
     3481 ttagagtcgg gaaccgctgc ctacagttac tcttcagttt tccataggtc atacctgcgg
     3541 tttcctttga ctcctctaag gagtcaacga gtagaaggat gagctgataa agtgatgata
     3601 ccgtgttaat ttttacaaaa tgctgtgcgt gagtgtgcat acacgtgcac atggatgtgt
     3661 ggatgtgtgt attctgtgtg ctattttgtc accttgatgt ctcctttcca ccaaagtttg
     3721 cagtaatact ctcttctgaa ggtacgcagt cagtgttata gagactgtca tggagaagag
     3781 gactcagttg acttttgcca ttttcatagg ggaacctttt aaaacaatct tttcagcagc
     3841 agacaccttt aaccctaata atctcaggcc ttgatgaaaa tactatattt tgtagattat
     3901 ggttaaagga agaaaattgc tagttccgta agataaatat gagctccatt taacttcttt
     3961 tttttaagcc tctaacaatt ttattgtaag taaacaaaat tatgtgtact tgttttattc
     4021 ggcacgtgaa aacagatatt tacagatata aaaaactcgt attgacagac gtttaaatgg
     4081 acagagtcaa gttgatagaa gcatgacaca aatttggtaa agcaaatctc agatactgac
     4141 actgaagcaa gtgctctcag atccatcaaa cagaccacag ccctcccttg ccaaaactcc
     4201 aatcaattct atcttagtat ctaagataga catcctgttt gtttttcata agtcaatctt
     4261 ggcactttta tgaacaatta gttcctctat tcacaaaagg catcataatt atttttactt
     4321 tcttaaagtt tgagggtttt ttggtttttg ttttaagtag ccaagatcta cagttgatct
     4381 tctaaaaggt cacgatctta gtaagttctt tttagttaca ggcaaaggac ccactttaca
     4441 gttggctttt aggatcttgc cattcaaaca gtctttgttg ttatggtaag cacacagaca
     4501 ctttgtacaa tattcaaatt gacagctttc ccgtttgcag actgctcgct ctaaatagtg
     4561 gtcatatttt gcagggaaat tatagcaagc acaggctttg aggcttccct tgttcttcaa
     4621 tgtctgccac ctccacgaac ttgttgtgcc agctgtaggt agaacctttc tgaccacgct
     4681 gactggagga cttgacctga acatcttttt ttgggaggtg cccaggtcga cgatgacttt
     4741 gaacagaagt tagtgcaggt ctgcccacaa catgtcctct cgttgcagca tgtagtgaca
     4801 acttactgct ttcaatgact ctgcatggtt ttgctgtaga gctggaccgc tcccttattg
     4861 ttttccagta tcttcttcca aattctgctc actttagaca ggtttattaa gtccgtgccc
     4921 cgagcttcat cacaatgtta gccaacaggt gcacgaatcc cctccgggag agctcagcca
     4981 ggagatctag gtgttccagg cccattttct tgccaattat actttgcagt ctaaagttgc
     5041 cgctggtgat aacttccttc agcatttctc gatccacttt agggtttcgc ttgccattct
     5101 tttttagtgt tgagcaaacc actctttgac aatgcaggac aggcagcagg ttttgttggg
     5161 atgctggtcc aggctctgtg atggcagcag gcgggcctgg ggactgtttc tgaaattctc
     5221 caggataagg atgccgtcgt cacggtcact ttgtgtaaaa gatgagtagc cactgtcctc
     5281 atacagtcta ctggcctcta gctcttctgt ttcgtttgaa ctatctagtg tgttttgtac
     5341 acgttgattc tccttgctat catgacccac aattggtgac tcgatgaaag acaacctctc
     5401 atggtttcta acacagtcct tacaggaagg tttcaaacac acgggactgt aggaaccttc
     5461 tctcccactg tcctcaggct tcaaccactt caagctcaga aagatcaggg ttgcaattaa
     5521 aacacttcat tgtaacagaa agaacagggc tttcttcttt atgtccacgg tcgtccacgc
     5581 gccaagacgg cagggacaga acgacggccg gcgcagatca ctgcaggtgt gcctgctcat
     5641 gcgggaaaac tcgggctcca gtgcagggga ggtggcggcg accataggaa agaggtggcc
     5701 ggccctccat ttaacttcta atatctgggt tagcattaca tgatgtgttg atcttatgct
     5761 cagcatttgt ctaagatgca atagtatcat tatcaatttc agaaatatgg actgaatatg
     5821 cttttttggt gatgaaatct atgtacgata tttatagtga tgtgctttta ttttctcatg
     5881 agaaactaaa tattgtgttg tacatttgtt tttagcatat attaaagttt taaaccaaat
     5941 gtgttaaagc ttatgctttg ccatgcaaat cccccagaag ttggtgagct caaatgtatc
     6001 ctacatccag ctgtagaaac ttgtcagaaa ttgtttaaat tttgtatata ggtgactgtt
     6061 taattttagc cactgcgctg aacagtattc aagttatata atatggcttt acacaagaaa
     6121 tgtgtggctt ctgttttgta tttttttcag tatagaagtt cctgtgtctt atttaaataa
     6181 agttattagt aaaactggaa t
//
