LOCUS       NM_001113323            2465 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus galactosidase, beta 1 like 3 (Glb1l3), mRNA.
ACCESSION   NM_001113323 XM_001476959 XM_983469
VERSION     NM_001113323.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2465)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2465)
  AUTHORS   Le Carre,J., Schorderet,D.F. and Cottet,S.
  TITLE     Altered expression of beta-galactosidase-1-like protein 3 (Glb1l3)
            in the retinal pigment epithelium (RPE)-specific 65-kDa protein
            knock-out mouse model of Leber's congenital amaurosis
  JOURNAL   Mol Vis 17, 1287-1297 (2011)
   PUBMED   21633714
  REMARK    GeneRIF: Early-onset downregulation of Glb1l3 in Rpe65-related
            disease. Impaired expression of Glb1l3 is mostly due to absence of
            chromophore 11-cis retinal.
REFERENCE   3  (bases 1 to 2465)
  AUTHORS   Nelson,P.S., Pritchard,C., Abbott,D. and Clegg,N.
  TITLE     The human (PEDB) and mouse (mPEDB) Prostate Expression Databases
  JOURNAL   Nucleic Acids Res 30 (1), 218-220 (2002)
   PUBMED   11752298
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DV051729.1, BC132200.1, BB281918.1, BY363615.1 and AC109831.5.
            
            On or before Jan 10, 2008 this sequence version replaced
            XM_001476959.1, XM_983469.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK014852.1, BC132200.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-207               DV051729.1         21-227
            208-2313            BC132200.1         1-2106
            2314-2393           BB281918.1         222-301
            2394-2425           BY363615.1         262-293
            2426-2426           AC109831.5         123483-123483       c
            2427-2465           BY363615.1         295-333
FEATURES             Location/Qualifiers
     source          1..2465
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 11.67 cM"
     gene            1..2465
                     /gene="Glb1l3"
                     /gene_synonym="4921509F24Rik"
                     /note="galactosidase, beta 1 like 3"
                     /db_xref="GeneID:70893"
                     /db_xref="MGI:MGI:1918143"
     exon            1..262
                     /gene="Glb1l3"
                     /gene_synonym="4921509F24Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             249..2237
                     /gene="Glb1l3"
                     /gene_synonym="4921509F24Rik"
                     /note="beta-galactosidase-1-like protein 3"
                     /codon_start=1
                     /product="beta-galactosidase-1-like protein 3 precursor"
                     /protein_id="NP_001106794.1"
                     /db_xref="CCDS:CCDS85650.1"
                     /db_xref="GeneID:70893"
                     /db_xref="MGI:MGI:1918143"
                     /translation="MAYLSKHRSWKKFMAIFFLPTVLSGFAPHSEEVFKSPARFSWSN
                     LTPSELKNRFVGLSTKTNALGKAYFTLEGHKFMIVGGSIHYFRVPREYWKDRLLKLQA
                     CGFNTVTTYIPWNLHEQERGKFDFSEILDLEAYVLLAKTIGLWVILRPGPYICAEVDL
                     GGLPSWLLRNPVTDLRTTNKGFIEAVDKYFDHLIPKILPLQYRHGGPVIAVQVENEYG
                     SFQKDRNYMNYLKKALLKRGIVELLLTSDDKDGIQIGSVNGALTTINMNSFTKDSFIK
                     LHKMQSDKPIMIMEYWTGWYDSWGSKHIEKSAEEIRHTVYKFISYGLSFNMYMFHGGT
                     NFGFINGGRYENHHISVVTSYDYDAVLSEAGDYTEKYFKLRKLFASGSARPLPPLPPL
                     IPKAIYPSVNLSFYLPLFDILPYLNQPVMLHTPVTMENLPINNGSGQPFGLVLYETSI
                     CSGGSLFASVHDSAQVFLNDQSIGILDENHEVLQIPKIQGCQLLRILVENQGRINYSW
                     RIQSEQKGLKEVVSIDGLLLTNFTIYSLDMKMSFFKRLRSASWRLAPKTYNGPAFYWG
                     ILNAGSSPTDTFLHLPNWHYGFVFINGRNLGRYWDIGPQRTLYLPGPWLHPEDNEVIV
                     FEKIEKGFDIQTRKKPQLQECYETGSGLPDAAGDADPC"
     exon            263..364
                     /gene="Glb1l3"
                     /gene_synonym="4921509F24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            365..577
                     /gene="Glb1l3"
                     /gene_synonym="4921509F24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            578..646
                     /gene="Glb1l3"
                     /gene_synonym="4921509F24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            647..742
                     /gene="Glb1l3"
                     /gene_synonym="4921509F24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            743..851
                     /gene="Glb1l3"
                     /gene_synonym="4921509F24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            852..944
                     /gene="Glb1l3"
                     /gene_synonym="4921509F24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            945..1026
                     /gene="Glb1l3"
                     /gene_synonym="4921509F24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1027..1091
                     /gene="Glb1l3"
                     /gene_synonym="4921509F24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1092..1176
                     /gene="Glb1l3"
                     /gene_synonym="4921509F24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1177..1314
                     /gene="Glb1l3"
                     /gene_synonym="4921509F24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1315..1395
                     /gene="Glb1l3"
                     /gene_synonym="4921509F24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1396..1502
                     /gene="Glb1l3"
                     /gene_synonym="4921509F24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1503..1643
                     /gene="Glb1l3"
                     /gene_synonym="4921509F24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1644..1715
                     /gene="Glb1l3"
                     /gene_synonym="4921509F24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1716..1794
                     /gene="Glb1l3"
                     /gene_synonym="4921509F24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1795..1882
                     /gene="Glb1l3"
                     /gene_synonym="4921509F24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1883..1994
                     /gene="Glb1l3"
                     /gene_synonym="4921509F24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1995..2111
                     /gene="Glb1l3"
                     /gene_synonym="4921509F24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2112..2465
                     /gene="Glb1l3"
                     /gene_synonym="4921509F24Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2366..2371
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Glb1l3"
                     /gene_synonym="4921509F24Rik"
                     /note="hexamer: AACAAA"
     polyA_site      2392
                     /gene="Glb1l3"
                     /gene_synonym="4921509F24Rik"
                     /note="major polyA site"
     regulatory      2444..2449
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Glb1l3"
                     /gene_synonym="4921509F24Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2465
                     /gene="Glb1l3"
                     /gene_synonym="4921509F24Rik"
ORIGIN      
        1 gtggacactg ttcctgaaga ccctggatct agatgctggc tgcaagcctg gcgtagcatt
       61 atggtgtcaa ggttgtgaga caccacctcc ccacctcccc acctccccat cccaactctt
      121 gacgtatttt catccagcca tcggcactac atcgggcctg acagacataa gttctgactg
      181 gaggttgtgt gtctgagaca cccaagaaag caggagctgc aaggaccttc gctccctggc
      241 ttccagtgat ggcatacctc agcaagcatc gttcctggaa gaaattcatg gccatcttct
      301 tcctgccaac tgtcctatcg ggttttgctc ctcactcaga ggaggtgttt aagtctcctg
      361 ccaggttcag ctggtctaat ctgaccccgt cagagctgaa gaacagattt gtagggctta
      421 gcactaaaac caatgctctg ggtaaagcat acttcaccct ggaaggtcac aaattcatga
      481 tcgttggagg ctccatacac tacttccggg tgcccaggga gtattggaag gaccgcttgt
      541 tgaagctgca ggcctgtgga ttcaacactg tcactaccta cattccatgg aacctccatg
      601 agcaagagag ggggaaattt gacttctctg aaatcctgga cctggaggcc tatgttttgc
      661 ttgctaagac tattgggctg tgggtgattc ttcgaccagg gccatacatc tgtgctgagg
      721 ttgacctggg tggattacct agctggcttc tgcgcaatcc tgtgacagat ctgagaacaa
      781 ccaacaaggg ctttattgag gctgtcgata agtattttga tcatctgatt cccaaaatac
      841 ttcctctcca gtaccgccat ggtggtcctg ttattgctgt ccaagtagag aatgaatatg
      901 gttcatttca aaaggatagg aactacatga attacttgaa gaaggctttg ctgaagagag
      961 ggattgtaga gctcctcttg acctcagatg ataaggatgg aattcagatc ggctctgtca
     1021 atggagcatt gacaactatc aatatgaatt catttactaa ggattccttt attaagcttc
     1081 ataaaatgca gagtgataag cccattatga ttatggaata ctggactggc tggtatgact
     1141 cgtgggggag taaacacatt gagaaaagtg cagaagaaat tcgacacaca gtatataaat
     1201 tcatcagcta tggactctct ttcaacatgt atatgttcca cggtggaacc aactttggtt
     1261 tcataaatgg aggccgctat gaaaatcatc acatcagtgt tgtgactagc tacgactatg
     1321 atgctgtgct gtctgaggct ggcgattaca cagagaagta tttcaagctt cggaaactct
     1381 ttgcatctgg ttcagcacgt cctctgcctc cattgcctcc tctcatcccc aaggctatct
     1441 atccctctgt gaatctctca ttctacctgc ctctgtttga tattctacca tacttaaatc
     1501 agcccgtcat gttacacact ccagtcacca tggagaatct tccaataaac aacggcagtg
     1561 gtcaaccatt tggcctggtc ctttatgaga cttccatctg ttctggaggc agtctctttg
     1621 cttcagttca tgattcagca caggtgtttt tgaatgacca aagtatagga attctggatg
     1681 agaatcatga ggttctgcaa attcctaaaa tccagggttg tcagcttctg aggatcctgg
     1741 ttgagaatca agggcgaatc aattactcat ggagaattca aagtgagcag aaaggattaa
     1801 aggaagtggt tagcatcgat ggccttttgc tgacgaattt taccatctat tctctggaca
     1861 tgaagatgag tttcttcaag aggctccgct ctgcatcctg gagacttgct ccaaagactt
     1921 ataacggccc tgccttctac tggggaatct tgaatgctgg ctcttctccc acagacacct
     1981 tcctgcacct accaaactgg cattatggat ttgtgttcat caatggacgc aatcttggaa
     2041 gatattggga cattggacct caaagaacac tgtaccttcc tggtccctgg cttcatccag
     2101 aagacaatga ggttatcgtg tttgagaaga tagagaaggg ttttgacatc cagacaagaa
     2161 agaaacccca gctgcaagag tgctacgaaa caggatctgg attgccggat gctgctggtg
     2221 atgctgatcc ctgctaagaa tattgaacat agtactgttt gaaaaaacat atgaaaataa
     2281 cctaaatacc caaagaaatt gttacatatc tcatactatc catttaatta ctatctttag
     2341 gctataaaaa tcaaagcctt taataaacaa atttatctag ttaaatgctt aattcttagt
     2401 aggttcttat tctctgtcaa gatatgcctt tagaaagaaa caaaataaaa acaaatttaa
     2461 ctccc
//
