LOCUS       NM_001411853            3974 bp    mRNA    linear   ROD 24-DEC-2024
DEFINITION  Mus musculus gap junction protein, alpha 10 (Gja10), mRNA.
ACCESSION   NM_001411853 NM_001411854
VERSION     NM_001411853.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3974)
  AUTHORS   Wutikeli,H., Yu,Y., Zhang,T., Cao,J., Nawy,S. and Shen,Y.
  TITLE     Role of Elavl-like RNA-binding protein in retinal development and
            signal transduction
  JOURNAL   Biochim Biophys Acta Mol Basis Dis 1871 (1), 167518 (2025)
   PUBMED   39307290
REFERENCE   2  (bases 1 to 3974)
  AUTHORS   Spinelli,M., Acevedo Harnecker,A., Block,C.T., Lindenthal,L.,
            Schuhmann,F., Greschner,M., Janssen-Bienhold,U., Dedek,K. and
            Puller,C.
  TITLE     The first interneuron of the mouse visual system is tailored to the
            natural environment through morphology and electrical coupling
  JOURNAL   iScience 27 (12), 111276 (2024)
   PUBMED   39628560
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3974)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   4  (bases 1 to 3974)
  AUTHORS   Soto,F., Shen,N. and Kerschensteiner,D.
  TITLE     AMIGO1 Promotes Axon Growth and Territory Matching in the Retina
  JOURNAL   J Neurosci 42 (13), 2678-2689 (2022)
   PUBMED   35169021
REFERENCE   5  (bases 1 to 3974)
  AUTHORS   Nemitz,L., Dedek,K. and Janssen-Bienhold,U.
  TITLE     Synaptic Remodeling in the Cone Pathway After Early Postnatal
            Horizontal Cell Ablation
  JOURNAL   Front Cell Neurosci 15, 657594 (2021)
   PUBMED   34122012
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 3974)
  AUTHORS   Hombach,S., Janssen-Bienhold,U., Sohl,G., Schubert,T., Bussow,H.,
            Ott,T., Weiler,R. and Willecke,K.
  TITLE     Functional expression of connexin57 in horizontal cells of the
            mouse retina
  JOURNAL   Eur J Neurosci 19 (10), 2633-2640 (2004)
   PUBMED   15147297
  REMARK    GeneRIF: Cx57 is the first connexin identified in mammalian
            horizontal cells and the first connexin whose expression is
            apparently restricted to only one type of neuron.
REFERENCE   7  (bases 1 to 3974)
  AUTHORS   Buniello,A., Montanaro,D., Volinia,S., Gasparini,P. and Marigo,V.
  TITLE     An expression atlas of connexin genes in the mouse
  JOURNAL   Genomics 83 (5), 812-820 (2004)
   PUBMED   15081111
REFERENCE   8  (bases 1 to 3974)
  AUTHORS   Sohl,G. and Willecke,K.
  TITLE     An update on connexin genes and their nomenclature in mouse and man
  JOURNAL   Cell Commun Adhes 10 (4-6), 173-180 (2003)
   PUBMED   14681012
  REMARK    Review article
REFERENCE   9  (bases 1 to 3974)
  AUTHORS   Houghton,F.D., Barr,K.J., Walter,G., Gabriel,H.D., Grummer,R.,
            Traub,O., Leese,H.J., Winterhager,E. and Kidder,G.M.
  TITLE     Functional significance of gap junctional coupling in
            preimplantation development
  JOURNAL   Biol Reprod 66 (5), 1403-1412 (2002)
   PUBMED   11967204
REFERENCE   10 (bases 1 to 3974)
  AUTHORS   Manthey,D., Bukauskas,F., Lee,C.G., Kozak,C.A. and Willecke,K.
  TITLE     Molecular cloning and functional expression of the mouse gap
            junction gene connexin-57 in human HeLa cells
  JOURNAL   J Biol Chem 274 (21), 14716-14723 (1999)
   PUBMED   10329667
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL831746.5.
            
            On Sep 9, 2022 this sequence version replaced NM_001411854.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17784643.1011204.1,
                                           SRR17784651.1121636.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMN00849384,
                                           SAMN01164137 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-114               AL831746.5         234053-234166       c
            115-1570            AL831746.5         227727-229182       c
            1571-3974           AL831746.5         221379-223782       c
FEATURES             Location/Qualifiers
     source          1..3974
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 14.25 cM"
     gene            1..3974
                     /gene="Gja10"
                     /gene_synonym="Cx-57; cx57; Cx59; Cxnn"
                     /note="gap junction protein, alpha 10"
                     /db_xref="GeneID:14610"
                     /db_xref="MGI:MGI:1339969"
     exon            1..114
                     /gene="Gja10"
                     /gene_synonym="Cx-57; cx57; Cx59; Cxnn"
                     /inference="alignment:Splign:2.1.0"
     exon            115..1570
                     /gene="Gja10"
                     /gene_synonym="Cx-57; cx57; Cx59; Cxnn"
                     /inference="alignment:Splign:2.1.0"
     exon            1571..3974
                     /gene="Gja10"
                     /gene_synonym="Cx-57; cx57; Cx59; Cxnn"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3950..3955
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gja10"
                     /gene_synonym="Cx-57; cx57; Cx59; Cxnn"
                     /note="hexamer: AATAAA"
     polyA_site      3974
                     /gene="Gja10"
                     /gene_synonym="Cx-57; cx57; Cx59; Cxnn"
                     /note="major polyA site"
ORIGIN      
        1 agagccttta taccagcaag cagcagcaga agcagctgtt ctgttaaacc gccacacatg
       61 gtgcaacttc agggttctgc aaactcaagg ggaattttct ggtctaactc taagatgtga
      121 cttcctaacc atgggagatt ggaatttact gggtggcatc ctagaggaag tccactccca
      181 ctccactata gtggggaaga tctggctgac catcctcttc atcttccgaa tgctggtact
      241 tggtgtcgct gctgaggacg tctgggatga tgagcagtcc gcctttgcct gcaacaccca
      301 gcagcccggt tgcaacaata tctgttacga tgatgctttc cccatctctt tgatcagatt
      361 ctgggttttg cagatcatct ttgtgtcttc cccttctttg gtgtatatgg gccatgccct
      421 ttatagactc agggactttg agaagcagag gcagaagaag aagttatacc ttagagccca
      481 gatggagaat ccagagctcg acctggagga gcaacaaagg gtagataaag agctgaggag
      541 actcgaggag cagaagagga ttcataaagt ccctctgaaa ggatgtctgc tgcgcaccta
      601 tgtcttacac atcctgacca gatcagtgct agaagtaggg ttcatgatag gccaatatat
      661 tctctatggg tttcaaatgc accccattta caagtgcacc caagccccct gccccaattc
      721 agtggactgc tttgtttcca ggcccacaga gaagaccatt ttcatgcttt tcatgcacag
      781 cattgcagcc atctccttgt tactcaatat cctggaaata tttcatctcg gcatcaggaa
      841 aatcatgagg gcactcgatg gcaaatccag cagtgggaac actgagaacg aaacaggccc
      901 tccattccat tcaacaaact actcagggac ccagcagtgt atgatctgtt cttctttacc
      961 tgaaagaatc tcactacttc aagccaacaa taaacagcaa gtcatccgag tcaatatacc
     1021 acggtctaaa agcatgtggc aaattccaca ccccaggcaa cttgaggtag atgtatcctg
     1081 tggcaaaaga gactgggctg agaaaattga gagctgtgca cagctccacg tccacagccc
     1141 ctgcccacat gaccgcagtg ccagaattca gcaccctgga cagcaaccgt gccattctgt
     1201 ctttggcccc aagaatgcaa tgtctcagtc ttggttcggt acaatgacgg cttctcaaca
     1261 ccgtccatca tctgcgttag aaacctggga gcgatcccag ggcccagaag cttcagggag
     1321 atctctcaca gatcgccaga gtcacttcca aggcagtgac ggcagtgcaa gagagagtgg
     1381 ggtttggaca gacagattag gcccaggaag tcgcaaggcc agctttctat cgaggctgat
     1441 gtcagaaaag ggacaacggc atagtgactc aggaagctca cggtctctga atagttcctg
     1501 cttggatttt tcacacggag aaaatagccc atcacctctg ccgtctgcca ctgggcacag
     1561 agcatcgatg aatatgcttc tagaactttc atctattatg aaaaaataac gcaccaagag
     1621 cagttgccat ctacaagatg aaagctatgc ctttgtcatc tcaaagagtc tggaagaact
     1681 ccacattgtc ctccagggtg tgtgtttgga tctggagtat cttccaaggt ccaggttaaa
     1741 ggtcccgaag ttgtccctta gagatcgtaa aatctttaag aggtcctagt gagaactctt
     1801 aggttactgg agatgtgcga tggaggaaat gtgaaccaca ttcctctctc ctcccttttt
     1861 ctctttcttt tttgaggcag gatctctcta tttagccctg gttgtccagg aactctctat
     1921 gtagagcagt ctgccctcaa gatcgcacag atccacctgc ctttgcctct ccagtgctgg
     1981 gactaaatgc acggtcacca agcctagcgc ccctcttctc ttttgcatac tggctacaag
     2041 gtaagtcttg tcatgtattc ctgccatgac gtgctggtaa gccacagccc ccaaaagcaa
     2101 tgagtccaac tgaccatggg ctaagacttc taaacctacc aaccaaaaga accctttcca
     2161 ctttggaagt taattctctt gggtatttgt tacagttaca gcaagcgact aacacacctg
     2221 gcaggcagag ttctcctctg ctggagactc ttatgaggca gcctcttaca gctctgcctg
     2281 gtcatgtcat ttgtggcagg tctgaagacc cactggggag gaattttaag agaaaaattc
     2341 tagagacaac tgcttatagt acctgccctg aggattggaa caccattctt ccttcctaat
     2401 atcagcagcc caatgagaca cctgtggtgg tttgaatagg tacgccccca tagactcgtg
     2461 tgtttgaatt cttgaccgat gaagagtggc acttttagga ggtgtgacct tgttgttgga
     2521 ggaagtgtgt cactgtgagg gtgggctttg aggtctcctg tacttaagct ctgcccagtg
     2581 tggaacctcg tccccttctg ctgcctgtgg atcaagatgt agaattctca gctccttctt
     2641 catcaccatg tccgcctgga cattgccatg tttcccacca tgatgataat ggactgaacc
     2701 tctgaaactg tgagcccaaa ttaaatgttt tccttgataa gatttgcctt ggtcatggtg
     2761 tctcttcagg acaacagaaa ccctaatgaa gacaacaccc aaagagagca ccagagttgc
     2821 agcatcaggc agagctcctt ctaacagatc cagagcaagc tggaggctcc aaactccacc
     2881 ttgtcttgag catacttcat gtttgtaagg gagaggctga taagaaactt ctcatgtagg
     2941 gcatggtggc acacgccttt aatctcagca ctcaggaggc agaggcagga ggatttctga
     3001 gttcaaagcc agcctggtct acaaagtgag ttccaggaca gccagggcta tacagagaaa
     3061 ccctgtctca aaaaacaaac aaacaaacaa aaagaaagaa aaaagaaaaa agaaactttt
     3121 tcacgtgatt tctcatatca gctcatatca tattatgttg tgagcatgaa gaaaatgaaa
     3181 ttttaattta taaatgttat tgaaattgag cgatgtctta aacaggagca aatatgccca
     3241 caatctgccg acacattcac tgtcagtgat aataaatgtt gactgtggcc cagaaatcgt
     3301 ttccaggggt taccaggggg cattacctta ttttcacctt ccccgtggtc aggacccacc
     3361 caggagagga gcttcagagg gccctagggc tccacagtgc agagaggcac gtaggttgtg
     3421 gaaggagtta tttagctctt tcatcttgta tcacataaac agactgccat gaaacatggg
     3481 ccacgtaccc tgtaacaaag atttcaagtt gtaagaacaa tcaatttggt tcagaatcat
     3541 gaagctcttt tttgttttgt tttgttttcc gagacagggt ttctcatgaa gctctgtccc
     3601 atgtatgtgc tgtgtgctgg atagttttat gttaacttga tacaagctaa agtcataggg
     3661 aatctcagtt aggaaaatgc ccccattata ttgggttgaa ggcaatcctg aaagcatttt
     3721 cctaattagt gtttgatgtg ggggggccca gcccattgtg ggtggtacca tcctgggctg
     3781 gtggtcctgg gttctataag aaggcaggct gagcaaacca cgaggagcaa tccagtaagc
     3841 aacactcctc catggcctct gcttcagctc ctgcttccag atccctgctc tgtttgagtt
     3901 cctgtcttga tttccttcat gatgaatagt aatatggaag tgtaagccaa ataaaccttt
     3961 tccttttcaa gctg
//
