LOCUS       NM_001403315            6047 bp    mRNA    linear   ROD 07-DEC-2024
DEFINITION  Mus musculus GRB10 interacting GYF protein 1 (Gigyf1), transcript
            variant 2, mRNA.
ACCESSION   NM_001403315
VERSION     NM_001403315.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6047)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6047)
  AUTHORS   Ding,Z., Huang,G., Wang,T., Duan,W., Li,H., Wang,Y., Jia,H.,
            Yang,Z., Wang,K., Chu,X., Kurtz-Nelson,E.C., Ahlers,K., Earl,R.K.,
            Han,Y., Feliciano,P., Chung,W.K., Eichler,E.E., Jiang,M. and
            Xiong,B.
  TITLE     Genetic Ablation of GIGYF1, Associated With Autism, Causes
            Behavioral and Neurodevelopmental Defects in Zebrafish and Mice
  JOURNAL   Biol Psychiatry 94 (10), 769-779 (2023)
   PUBMED   36924980
  REMARK    GeneRIF: Genetic Ablation of GIGYF1, Associated With Autism, Causes
            Behavioral and Neurodevelopmental Defects in Zebrafish and Mice.
REFERENCE   3  (bases 1 to 6047)
  AUTHORS   Chen,G., Yu,B., Tan,S., Tan,J., Jia,X., Zhang,Q., Zhang,X.,
            Jiang,Q., Hua,Y., Han,Y., Luo,S., Hoekzema,K., Bernier,R.A.,
            Earl,R.K., Kurtz-Nelson,E.C., Idleburg,M.J., Madan-Khetarpal,S.,
            Clark,R., Sebastian,J., Fernandez-Jaen,A., Alvarez,S., King,S.D.,
            Ramos,L.L., Santos,M.L.S., Martin,D.M., Brooks,D., Symonds,J.D.,
            Cutcutache,I., Pan,Q., Hu,Z., Yuan,L., Eichler,E.E., Xia,K. and
            Guo,H.
  TITLE     GIGYF1 disruption associates with autism and impaired IGF-1R
            signaling
  JOURNAL   J Clin Invest 132 (19), e159806 (2022)
   PUBMED   35917186
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6047)
  AUTHORS   Giovannone,B., Tsiaras,W.G., de la Monte,S., Klysik,J., Lautier,C.,
            Karashchuk,G., Goldwurm,S. and Smith,R.J.
  TITLE     GIGYF2 gene disruption in mice results in neurodegeneration and
            altered insulin-like growth factor signaling
  JOURNAL   Hum Mol Genet 18 (23), 4629-4639 (2009)
   PUBMED   19744960
REFERENCE   5  (bases 1 to 6047)
  AUTHORS   Giovannone,B., Lee,E., Laviola,L., Giorgino,F., Cleveland,K.A. and
            Smith,R.J.
  TITLE     Two novel proteins that are linked to insulin-like growth factor
            (IGF-I) receptors by the Grb10 adapter and modulate IGF-I signaling
  JOURNAL   J Biol Chem 278 (34), 31564-31573 (2003)
   PUBMED   12771153
  REMARK    GeneRIF: identification of proteins linked to insulin-like growth
            factor (IGF-I) receptors by the Grb10 adapter and modulate IGF-I
            signaling
REFERENCE   6  (bases 1 to 6047)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   7  (bases 1 to 6047)
  AUTHORS   Wilson,M.D., Riemer,C., Martindale,D.W., Schnupf,P., Boright,A.P.,
            Cheung,T.L., Hardy,D.M., Schwartz,S., Scherer,S.W., Tsui,L.C.,
            Miller,W. and Koop,B.F.
  TITLE     Comparative analysis of the gene-dense ACHE/TFR2 region on human
            chromosome 7q22 with the orthologous region on mouse chromosome 5
  JOURNAL   Nucleic Acids Res 29 (6), 1352-1365 (2001)
   PUBMED   11239002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC148018.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13422598.546305.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-183               AC148018.3         142520-142702
            184-410             AC148018.3         149467-149693
            411-541             AC148018.3         150564-150694
            542-607             AC148018.3         150770-150835
            608-716             AC148018.3         150960-151068
            717-846             AC148018.3         151165-151294
            847-942             AC148018.3         151392-151487
            943-1054            AC148018.3         151588-151699
            1055-1163           AC148018.3         151819-151927
            1164-1204           AC148018.3         152110-152150
            1205-1369           AC148018.3         152294-152458
            1370-1623           AC148018.3         152629-152882
            1624-1741           AC148018.3         152967-153084
            1742-1876           AC148018.3         153930-154064
            1877-1977           AC148018.3         154205-154305
            1978-2149           AC148018.3         154460-154631
            2150-2316           AC148018.3         154743-154909
            2317-2417           AC148018.3         155037-155137
            2418-2537           AC148018.3         155219-155338
            2538-2638           AC148018.3         155484-155584
            2639-2721           AC148018.3         155881-155963
            2722-2868           AC148018.3         156044-156190
            2869-3093           AC148018.3         156271-156495
            3094-3284           AC148018.3         156733-156923
            3285-3445           AC148018.3         157013-157173
            3446-3633           AC148018.3         157254-157441
            3634-3763           AC148018.3         157512-157641
            3764-6047           AC148018.3         157734-160017
FEATURES             Location/Qualifiers
     source          1..6047
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 76.53 cM"
     gene            1..6047
                     /gene="Gigyf1"
                     /gene_synonym="mKIAA4110; Perq1"
                     /note="GRB10 interacting GYF protein 1"
                     /db_xref="GeneID:57330"
                     /db_xref="MGI:MGI:1888677"
     exon            1..183
                     /gene="Gigyf1"
                     /gene_synonym="mKIAA4110; Perq1"
                     /inference="alignment:Splign:2.1.0"
     exon            184..410
                     /gene="Gigyf1"
                     /gene_synonym="mKIAA4110; Perq1"
                     /inference="alignment:Splign:2.1.0"
     exon            411..541
                     /gene="Gigyf1"
                     /gene_synonym="mKIAA4110; Perq1"
                     /inference="alignment:Splign:2.1.0"
     exon            542..607
                     /gene="Gigyf1"
                     /gene_synonym="mKIAA4110; Perq1"
                     /inference="alignment:Splign:2.1.0"
     exon            608..716
                     /gene="Gigyf1"
                     /gene_synonym="mKIAA4110; Perq1"
                     /inference="alignment:Splign:2.1.0"
     CDS             682..3816
                     /gene="Gigyf1"
                     /gene_synonym="mKIAA4110; Perq1"
                     /note="isoform a is encoded by transcript variant 2; PERQ
                     amino acid-rich with GYF domain-containing protein 1;
                     GRB10 interacting GYF protein 2; PERQ amino acid rich,
                     with GYF domain 1"
                     /codon_start=1
                     /product="GRB10-interacting GYF protein 1 isoform a"
                     /protein_id="NP_001390244.1"
                     /db_xref="GeneID:57330"
                     /db_xref="MGI:MGI:1888677"
                     /translation="MAAETLNFGPEWLRALSSGGSVASPPPSPAMPKYKLADYRYGRE
                     EMLALYVKENKVPEELQDKEFAAVLQEEPLQPLALEPLTEEEQRNFSLSVNSVAVLRL
                     MGKGAGPPLPATSRGRGSTRSRGRGRGDSCFYQRSIEEGDGAFGRNPREIQRSQSWDD
                     RGERRFEKPARRDGVRSGFEEGGAGPRKEHARSDSENWRSLREEQEDDGSWRLGAGPR
                     RDGDRWRSTSPDGGPRSAGWREHGERRRKFDFDLRGERGGCGEEDGRVGGGNSHLRRC
                     RGLDGFEDDKDGLPEWCLEDEDEEMGTFDASGAFLPLKKGPKEAIPEEQELDFRGLEE
                     EEEEEEEPSEGVDEERPEAGGKEATPLPPPENSSSPSSLPALGPLWTTNEEGGEAVEK
                     ELPPAEGDELRGLSLSPRISSPPGPPGDLEDEEGLKHLQQEAEKLVASLQDSSLEEEQ
                     FTAAMQTQGLRHSTAATALPLSHGAARKWFYKDPQGEIQGPFTTQEMAEWFQAGYFSM
                     SLLVKRGCDEGFQPLGEVIKMWGRVPFAPGPSPPPLLGNMDQERLKKQQELAAAALYQ
                     QLQHQHFLQLVGSRQLPQCTTLREKAAMGDLTPPQQQQLTTFLQQLQALKTPRGGDQN
                     LLPTMSRSLSVPDSGPLWDLHTSASSQSGGEASLWDIPINSSTQGPILEQLQLQHKFQ
                     ERREVELRAKREEEERKRREEKRRQQQQQQEEQKRRQEEEELFRRKQVRQQELLLKLL
                     QQQQATNVPVPPAPSSPPPLWAGLAKQGLSMKTLLELQMESERQLHKQAAPREPLRAQ
                     APNHRVQLGGLGSAPLNQWVSEAGPLWGGPDKSGGSSGGNLGLWEDTLKSGGSLARSL
                     GLKSSRSSPSLSDSYSHLSGRPVRKKTEEEEKLLKLLQGIPRPQDGFTQWCEQMLHTL
                     STAGSLDVPMAVAILKEVESPYDVHDYIRSCLGDTLEAKEFAKQFLERRAKQKASQQR
                     QQQQQQQQQQQQEAWLSSTSLQTAFQANHSTKLGPGEGSKAKRRALMLHSDPSILGYS
                     LHGPSGEIESVDDY"
     exon            717..846
                     /gene="Gigyf1"
                     /gene_synonym="mKIAA4110; Perq1"
                     /inference="alignment:Splign:2.1.0"
     exon            847..942
                     /gene="Gigyf1"
                     /gene_synonym="mKIAA4110; Perq1"
                     /inference="alignment:Splign:2.1.0"
     exon            943..1054
                     /gene="Gigyf1"
                     /gene_synonym="mKIAA4110; Perq1"
                     /inference="alignment:Splign:2.1.0"
     exon            1055..1163
                     /gene="Gigyf1"
                     /gene_synonym="mKIAA4110; Perq1"
                     /inference="alignment:Splign:2.1.0"
     exon            1164..1204
                     /gene="Gigyf1"
                     /gene_synonym="mKIAA4110; Perq1"
                     /inference="alignment:Splign:2.1.0"
     exon            1205..1369
                     /gene="Gigyf1"
                     /gene_synonym="mKIAA4110; Perq1"
                     /inference="alignment:Splign:2.1.0"
     exon            1370..1623
                     /gene="Gigyf1"
                     /gene_synonym="mKIAA4110; Perq1"
                     /inference="alignment:Splign:2.1.0"
     exon            1624..1741
                     /gene="Gigyf1"
                     /gene_synonym="mKIAA4110; Perq1"
                     /inference="alignment:Splign:2.1.0"
     exon            1742..1876
                     /gene="Gigyf1"
                     /gene_synonym="mKIAA4110; Perq1"
                     /inference="alignment:Splign:2.1.0"
     exon            1877..1977
                     /gene="Gigyf1"
                     /gene_synonym="mKIAA4110; Perq1"
                     /inference="alignment:Splign:2.1.0"
     exon            1978..2149
                     /gene="Gigyf1"
                     /gene_synonym="mKIAA4110; Perq1"
                     /inference="alignment:Splign:2.1.0"
     exon            2150..2316
                     /gene="Gigyf1"
                     /gene_synonym="mKIAA4110; Perq1"
                     /inference="alignment:Splign:2.1.0"
     exon            2317..2417
                     /gene="Gigyf1"
                     /gene_synonym="mKIAA4110; Perq1"
                     /inference="alignment:Splign:2.1.0"
     exon            2418..2537
                     /gene="Gigyf1"
                     /gene_synonym="mKIAA4110; Perq1"
                     /inference="alignment:Splign:2.1.0"
     exon            2538..2638
                     /gene="Gigyf1"
                     /gene_synonym="mKIAA4110; Perq1"
                     /inference="alignment:Splign:2.1.0"
     exon            2639..2721
                     /gene="Gigyf1"
                     /gene_synonym="mKIAA4110; Perq1"
                     /inference="alignment:Splign:2.1.0"
     exon            2722..2868
                     /gene="Gigyf1"
                     /gene_synonym="mKIAA4110; Perq1"
                     /inference="alignment:Splign:2.1.0"
     exon            2869..3093
                     /gene="Gigyf1"
                     /gene_synonym="mKIAA4110; Perq1"
                     /inference="alignment:Splign:2.1.0"
     exon            3094..3284
                     /gene="Gigyf1"
                     /gene_synonym="mKIAA4110; Perq1"
                     /inference="alignment:Splign:2.1.0"
     exon            3285..3445
                     /gene="Gigyf1"
                     /gene_synonym="mKIAA4110; Perq1"
                     /inference="alignment:Splign:2.1.0"
     exon            3446..3633
                     /gene="Gigyf1"
                     /gene_synonym="mKIAA4110; Perq1"
                     /inference="alignment:Splign:2.1.0"
     exon            3634..3763
                     /gene="Gigyf1"
                     /gene_synonym="mKIAA4110; Perq1"
                     /inference="alignment:Splign:2.1.0"
     exon            3764..6047
                     /gene="Gigyf1"
                     /gene_synonym="mKIAA4110; Perq1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6019..6024
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gigyf1"
                     /gene_synonym="mKIAA4110; Perq1"
                     /note="hexamer: AATAAA"
     polyA_site      6047
                     /gene="Gigyf1"
                     /gene_synonym="mKIAA4110; Perq1"
                     /note="major polyA site"
ORIGIN      
        1 gctacaaaca caaacagaga ggagcggccg ccgcgggagc gccagcgccc ccccccagtc
       61 cccccctgcc gccgccgccg ccgtcccggc cctccgcgcc acccgcccgt caccgccgcc
      121 gccgctgccg cgcccgggtc accaacgccc cgggggaccg ggaacctcgc gcccccccct
      181 ccgattcctg gcgtcctgca gcggatggcg actggagagg cacactggtc cagcctcctg
      241 cccagcctgt gataaaaaac ccacgtattc cccccggaca ctgcctgtcc ttccttctct
      301 actctgccct tcctgagagt ctcctaccca ggaccctaga ggaacttgcc ctgttgctgc
      361 cactgctgcc tcattagcca ctagagactg aacttgcctc ttcccatatg gatctctccc
      421 agatgtgaaa gtttctccca ggcacttaga ggctagagct agttgcttgg ggatcctagt
      481 tcagcgcagc ccggcccctg tgagaccaga gagcccttgt ttccctggac agaactgtca
      541 ggactctccc ctaccctgac tcagctttgg ttaactcatg gtgtgagtgg tcacctgtct
      601 ggtgtaggta tttggacagt actctcctgg tcctgtctct gccattcatc cttgaccttt
      661 gagaagcatc gaagctccac aatggcagca gagacactca actttgggcc tgagtggctg
      721 agagcccttt cgagtggtgg cagcgtggcc tctccacccc catctcctgc catgcccaaa
      781 tacaagctgg cagattaccg ctatgggcga gaggagatgc tggccctcta tgtcaaggag
      841 aacaaggtcc cggaggaact acaggacaag gagtttgctg cagtgttaca agaggaaccg
      901 ctgcaacctc tggctctgga gcctctgact gaggaggagc agagaaactt ctcgctgtcg
      961 gtgaacagtg tggctgtgct gagactgatg gggaaagggg ctgggccccc tttgcctgcc
     1021 acctcccgtg gcaggggcag cactcggagc cgagggcgag gccgtggtga cagctgcttt
     1081 taccaaagaa gcattgagga aggcgatggg gccttcggaa ggaatcctcg ggagatccag
     1141 cgaagccaaa gctgggatga cagaggcgag aggcggtttg agaagcctgc aaggagggat
     1201 ggagtacggt ctggctttga ggagggaggg gctggcccaa ggaaggagca tgcacgctca
     1261 gacagtgaga attggcgctc acttcgagag gagcaagagg atgatggcag ctggagactt
     1321 ggggcgggac cccggcgaga tggtgatcgc tggcgttcca ccagccctga tggtggtccc
     1381 cgctctgctg gctggcggga gcatggggag cggaggcgca agtttgattt tgatttgcga
     1441 ggggagcgcg gagggtgtgg tgaagaggat gggcgggttg ggggcggcaa ctctcacctc
     1501 cggagatgcc gggggctcga tggctttgaa gatgacaagg atgggctccc cgagtggtgc
     1561 ctggaggatg aggatgagga gatgggcact ttcgatgcct ccggagcctt cctgcccctt
     1621 aagaagggcc ccaaggaagc catccctgag gagcaggagc ttgatttccg gggcctggag
     1681 gaggaggagg aggaggagga ggagccgtca gaaggggtgg atgaagagag gcctgaggca
     1741 ggagggaagg aggcaacccc attgccgcct ccagagaact ccagctcacc gtcttcactg
     1801 ccagccttgg gtcctctctg gacgacaaat gaggagggtg gtgaggcagt ggagaaagag
     1861 ctgcctcctg ctgaaggtga cgagttgagg ggactgtctc tgagtcctag aatcagttca
     1921 cctcctggcc cacctggaga tctagaagac gaagaaggct tgaagcactt gcagcaggag
     1981 gcagagaagc tggtggcctc cctgcaggac agctccctgg aggaggagca gttcaccgct
     2041 gccatgcaaa cccagggcct ccgccactcc acagctgcca ctgcccttcc cctcagccat
     2101 ggcgctgccc gaaagtggtt ctacaaggac ccacaggggg aaatccaagg ccctttcacg
     2161 acccaggaga tggctgagtg gttccaggct ggctacttct ccatgtcact cttagtgaag
     2221 aggggctgcg atgagggttt ccagcctctg ggagaggtga tcaagatgtg gggccgtgtg
     2281 ccctttgccc cagggccctc gccacccccg ctgctgggca acatggatca ggagcggctg
     2341 aagaagcagc aggagctggc tgcggcagcc ctgtaccagc agctgcagca ccagcacttt
     2401 ctgcagctgg ttggcagccg ccagctcccg cagtgtacga cgctccggga aaaggcagct
     2461 atgggggacc tgacgccgcc gcagcagcag cagctcacta cgttcctgca gcagctccag
     2521 gctctcaaaa cccccagagg tggagaccag aacctgctcc cgacgatgag ccggtccttg
     2581 tcggtgccag attcaggccc cctctgggac ttacatacct cagcttcatc acagtcaggt
     2641 ggtgaggcca gtctttggga cataccaatt aactcttcga ctcagggtcc aattctagaa
     2701 cagctccaac tgcagcataa atttcaagag cgcagagaag tggagctcag ggcgaagcgg
     2761 gaggaggagg agcgcaaacg acgggaggag aagcggcgcc aacagcagca gcagcaggag
     2821 gagcagaagc gacggcagga agaggaggag ctctttcggc gcaagcaggt acggcagcag
     2881 gaattgttgc tgaagctgct acagcagcag caagcgacga atgtccctgt gccccctgca
     2941 cccagctccc cacccccgct ctgggctggc ctagccaagc agggcctgtc catgaagact
     3001 ctgctggagc tgcagatgga aagtgagcgc caactgcaca agcaggcggc accgcgggag
     3061 cctctgcggg cccaggcccc caaccaccga gtgcagcttg ggggcttggg ctctgcccct
     3121 ctgaaccagt gggtgtctga ggctgggcca ctatggggcg ggccagacaa gagtgggggc
     3181 agcagcggtg gcaacctggg actctgggaa gatactctca agagtggcgg gagcctggcc
     3241 cgaagcctgg gcctgaagag cagtcggagc agcccgtctc tcagtgactc gtacagccac
     3301 ctgtcaggcc gacctgttcg caaaaagaca gaagaggaag agaagttgct gaagctgctg
     3361 cagggcatcc ctcggcccca ggacggcttc acgcagtggt gtgagcaaat gctgcacacc
     3421 ctgagcactg cgggcagcct agacgttccc atggctgtcg ccatcctcaa ggaggtggag
     3481 tccccttacg atgtccatga ttatattcgt tcctgcctgg gggacacgct ggaagccaaa
     3541 gaatttgcca aacaattcct ggagcggagg gccaagcaga aagccagcca acagcggcag
     3601 cagcagcagc agcagcagca gcagcagcag caggaggcct ggctgagcag cacctcccta
     3661 cagacagcct ttcaggccaa ccacagcacc aaactgggcc ctggggaggg cagcaaggcc
     3721 aaaaggcggg cactgatgct tcactccgac cctagcatct tggggtactc cctgcacggc
     3781 ccttccggtg agatcgagag cgtggatgac tactgaccag cctgtcccac ctgccccctg
     3841 ggccttagac tcgggtggtg gcagcagcat ggacccttgg gtctccagcc tgcaggctcc
     3901 cacagggagc agaggaggaa gcgagcgagc gagcgagtgg ggcagggtcc ccagcacttg
     3961 ttacaaacca cacgatgcac cttaactcac ccgccacgag gcactttaca gatgggggag
     4021 gggcctttct tttcctcttt aattttaaac attaggagag acagaaatat catccaaaag
     4081 ctagacggta gacccctaca cccctttggg aataatgggt gtgacattgg aaggtccaca
     4141 gaggtttgtt tttggttttt tgttttgttt tgtttttatt ttttagaaaa aaaaaaaaag
     4201 ataaaaaaaa taatgaaaaa aaaagttagg ctgaaaggaa aaaaaaaatc acactgttat
     4261 ttttggccag tgggtaccag gccccatgga cctgtcctgc ctggcttccc tgaggctgca
     4321 cttaccctgc tgccccagaa ggtgggtcat tggggtgact tgtcagctgg gtgctggcag
     4381 tttgcacagc gagcgagcgg aggccctctc cagaagcccc gcccactgga cctgctgtga
     4441 tcagctcctg tggccgttac tgtggcaggt gtcctggtaa ggggccagag tcgcccctta
     4501 cctcagctgc tttgggagga acgttgcaca aattggatga gctgcctcag ctccctctcc
     4561 ccacaccccc gaaacagccc tcccacactg gctgagggag ctggggaaag ccctgtcagt
     4621 gccagcctgt cagctgggct ctgaactcag gcctgctgag gggctgaccc ccactgctgc
     4681 catttcgggg gacagcctgg gtgtgacact gaaagcccca gctccctgcc tttgccacat
     4741 gaatgtattt tctggccccc aagcccgtct caccccctct gagaagggac tcagcccttc
     4801 ctccaggagc tggagaacac ccctcctttt atcatggccg aggccttgct tgtgagggaa
     4861 ggacaccgaa ggagtggctt ggggcggaac ctaggggggc cccgtggtga gaaccccctg
     4921 atcagcagcc agctgtgtgg gaagcagacc acagctccgt acctgacccc tccattgacc
     4981 aaatgggaga ggagtgagca gcccctctcc ttgatgtttt ttgtgttggg tgtaaggctg
     5041 gaggtcgaga gcgcctgtgt cctggctggg ggctgccttg cctgttgctc gccgacctca
     5101 ctcctagccc tcccgccctg cccatgcttg tcttcattgt tgtttgcccc cccccccccc
     5161 tttcttttta atatactgtg ttagtgactc tcccatcgac ctcattgctc agaatgcagt
     5221 attagggcta gcgagcgagc ctgccactgc ctcctccatg aatgtatttc tagtttctgt
     5281 cctggggaag tagggagtgg ccccaggttc ttctttccca tccatcccca cagaggtgac
     5341 cttttgtttt cctttccact tttttttttt cttttttttc tttttttttt tttttgcacc
     5401 aaagtggcaa ctgggtcagt gttggggatc aggctggctt tgggtggaag ggcccctcca
     5461 cctgcttctc cctggttttg acagtgttag cgtctgtgaa aagacaatat tctctctaaa
     5521 gcaataaggg ggtgatgggc cagggggaaa cgtcttgctg ctgctggccc cccagctccc
     5581 tttccctctt gccattgtgg tggcattgga gggatgggag agactcctgt tgtgactgaa
     5641 tgtaacctac cctgcccctg ccacagccaa tgcaggggga gggagggcac ttgtctcttc
     5701 ctacccctcc ccccagctaa agagactgaa cttgggggcc catgagcctg gagaggcctt
     5761 aaccctgtga ggaagtgtgg ggcctctccc accccatccc ctctgagagt ggccaatgtt
     5821 tacaagccct gagccccagc ccagggactc agaccccccc cccccatctt aatcctttcc
     5881 ccatcccagt cttacagggc cccactgccc caccctaccc ccttggggtt cagggtagtg
     5941 tgggtgtcct gtgtatccca gtttacccta cctctaccct gtgtgacttc cctaataccc
     6001 actcttgtaa atactcccaa taaaacttgg tgtgttctcc cagtcta
//
