LOCUS       NM_144786               2611 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus gamma-glutamyltransferase 7 (Ggt7), transcript variant
            2, mRNA.
ACCESSION   NM_144786 XM_976561
VERSION     NM_144786.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2611)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2611)
  AUTHORS   Clotman,F., Jacquemin,P., Plumb-Rudewiez,N., Pierreux,C.E., Van der
            Smissen,P., Dietz,H.C., Courtoy,P.J., Rousseau,G.G. and
            Lemaigre,F.P.
  TITLE     Control of liver cell fate decision by a gradient of TGF beta
            signaling modulated by Onecut transcription factors
  JOURNAL   Genes Dev 19 (16), 1849-1854 (2005)
   PUBMED   16103213
REFERENCE   3  (bases 1 to 2611)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Kitamura,H., Nakagawa,T., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of FLJ
            genes: the complete nucleotide sequences of 110 mouse
            FLJ-homologous cDnas identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (2), 127-135 (2004)
   PUBMED   15449545
REFERENCE   4  (bases 1 to 2611)
  AUTHORS   Ehringer,M.A., Thompson,J., Conroy,O., Xu,Y., Yang,F., Canniff,J.,
            Beeson,M., Gordon,L., Bennett,B., Johnson,T.E. and Sikela,J.M.
  TITLE     High-throughput sequence identification of gene coding variants
            within alcohol-related QTLs
  JOURNAL   Mamm Genome 12 (8), 657-663 (2001)
   PUBMED   11471062
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY127251.1, AK032051.1 and AK177521.1.
            
            On Mar 14, 2009 this sequence version replaced NM_144786.1.
            
            Transcript Variant: This variant (2) uses an alternate in-frame
            splice junction compared to variant 1. The resulting isoform (2)
            has the same N- and C-termini but is shorter compared to isoform 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK032051.1, BC005772.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3                 BY127251.1         1-3
            4-2602              AK032051.1         2-2600
            2603-2611           AK177521.1         414-422
FEATURES             Location/Qualifiers
     source          1..2611
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 77.26 cM"
     gene            1..2611
                     /gene="Ggt7"
                     /gene_synonym="1110017C11Rik; 6330563L03Rik; Ggtl3"
                     /note="gamma-glutamyltransferase 7"
                     /db_xref="GeneID:207182"
                     /db_xref="MGI:MGI:1913385"
     exon            1..218
                     /gene="Ggt7"
                     /gene_synonym="1110017C11Rik; 6330563L03Rik; Ggtl3"
                     /inference="alignment:Splign:2.1.0"
     CDS             50..2038
                     /gene="Ggt7"
                     /gene_synonym="1110017C11Rik; 6330563L03Rik; Ggtl3"
                     /EC_number="2.3.2.2"
                     /EC_number="3.4.19.13"
                     /note="isoform 2 is encoded by transcript variant 2;
                     gamma-glutamyltransferase-like 3; mFLJ00311 protein; GGT
                     7; gamma-glutamyltranspeptidase 7; glutathione hydrolase
                     7"
                     /codon_start=1
                     /product="glutathione hydrolase 7 isoform 2"
                     /protein_id="NP_659035.2"
                     /db_xref="CCDS:CCDS16949.1"
                     /db_xref="GeneID:207182"
                     /db_xref="MGI:MGI:1913385"
                     /translation="MAAENEASQESALGAYSPVDYMSITSFPRLPEDEPAPAAPLRGR
                     KDEDAFLGDPDTDPDSFLKSARLQRLPSSSSEMGSQDGSPLRETRKDPFSAAAAECSC
                     RQDGLTVIVTACLTFATGVTVALVMQIYFGDPQIFQQGAVVTDASSCTALGMEVLSKQ
                     GSSVDAAVAAALCLGIVAPHSSGLGGGGVMLVHDIRRNESHLIDFRESAPGALREEAL
                     QRSWDTKPGLLVGVPGMVKGLHEAHQLYGRLPWSQVLAFAAAVAQDGFNVTHDLAHAL
                     AEQLPPNASDRFLDTFLPLGHPPLPGSLLRRPDLAEVLDILGTSGPAAFYNGGNLTLE
                     MVAEAQHAGGVITEEDFSNYSALTEKPVCGVYRGHLVLSPPPPHTGPALISALNILEG
                     FNLTSLVSREQALHWVAETLKIALALASRLGDPVYDSTITESMDDMLSKVEAANFRGH
                     ISDSQAAPAPLLPVYELDGAPTAAQVLVMGPDDFIVAMVSSLNRPFGSGLLTPSGILL
                     NSQMLDFSWPNRTANHSAPSLENSVQPGKRPLSFLLPTVVRPAEGLCGTYLALGANGA
                     ARGLSGLTQVLLNVLTLNRNLSDSLARGRLHPDLQSNLLQVDSEFTEEEIEFLEARGH
                     HVEKVDVLSWVHGSRRTNTFIIGVKDPRSPDAAGATIL"
     exon            219..454
                     /gene="Ggt7"
                     /gene_synonym="1110017C11Rik; 6330563L03Rik; Ggtl3"
                     /inference="alignment:Splign:2.1.0"
     exon            455..606
                     /gene="Ggt7"
                     /gene_synonym="1110017C11Rik; 6330563L03Rik; Ggtl3"
                     /inference="alignment:Splign:2.1.0"
     exon            607..724
                     /gene="Ggt7"
                     /gene_synonym="1110017C11Rik; 6330563L03Rik; Ggtl3"
                     /inference="alignment:Splign:2.1.0"
     exon            725..792
                     /gene="Ggt7"
                     /gene_synonym="1110017C11Rik; 6330563L03Rik; Ggtl3"
                     /inference="alignment:Splign:2.1.0"
     exon            793..866
                     /gene="Ggt7"
                     /gene_synonym="1110017C11Rik; 6330563L03Rik; Ggtl3"
                     /inference="alignment:Splign:2.1.0"
     exon            867..1063
                     /gene="Ggt7"
                     /gene_synonym="1110017C11Rik; 6330563L03Rik; Ggtl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1064..1151
                     /gene="Ggt7"
                     /gene_synonym="1110017C11Rik; 6330563L03Rik; Ggtl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1152..1279
                     /gene="Ggt7"
                     /gene_synonym="1110017C11Rik; 6330563L03Rik; Ggtl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1280..1368
                     /gene="Ggt7"
                     /gene_synonym="1110017C11Rik; 6330563L03Rik; Ggtl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1369..1518
                     /gene="Ggt7"
                     /gene_synonym="1110017C11Rik; 6330563L03Rik; Ggtl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1519..1636
                     /gene="Ggt7"
                     /gene_synonym="1110017C11Rik; 6330563L03Rik; Ggtl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1637..1774
                     /gene="Ggt7"
                     /gene_synonym="1110017C11Rik; 6330563L03Rik; Ggtl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1775..1874
                     /gene="Ggt7"
                     /gene_synonym="1110017C11Rik; 6330563L03Rik; Ggtl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1875..2611
                     /gene="Ggt7"
                     /gene_synonym="1110017C11Rik; 6330563L03Rik; Ggtl3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2584..2589
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ggt7"
                     /gene_synonym="1110017C11Rik; 6330563L03Rik; Ggtl3"
                     /note="hexamer: ATTAAA"
     polyA_site      2596
                     /gene="Ggt7"
                     /gene_synonym="1110017C11Rik; 6330563L03Rik; Ggtl3"
                     /note="major polyA site"
ORIGIN      
        1 ttcactgcca cttccggcag gcgctgcgct gctgggggtt agggcgagga tggcggctga
       61 gaacgaggct agccaggaga gcgccctagg cgcctactca ccagtggact atatgagcat
      121 caccagcttc ccgaggctgc cggaggacga gccagcgcct gcggccccac tgaggggccg
      181 taaggacgag gacgccttct tgggagaccc ggatactgac ccggactcct tcctcaagtc
      241 tgcccggctt cagcggctgc cttcgtcgtc atcggagatg ggcagccagg acgggtcacc
      301 attacgggag actcgcaagg acccattctc agctgcagca gcagagtgtt cttgccgcca
      361 ggatgggctc acggtcattg tcaccgcctg cctcactttt gccaccggtg tcaccgtggc
      421 gctggtcatg caaatctact tcggggatcc ccagatcttc cagcagggtg ctgtggtgac
      481 ggatgcctcc agttgcacgg cgctgggcat ggaggtgctc agtaaacagg gctcttcagt
      541 ggatgcagct gtggccgcag ccttgtgttt ggggattgtg gctccacaca gttctggcct
      601 gggcggtggg ggcgtgatgt tggtacatga tatccggcgg aatgagagcc acctaattga
      661 tttccgggag tctgcacccg gggccctcag agaagaggct ctgcagagat cctgggatac
      721 caagcctggg ctcttggtgg gggtccccgg aatggtgaaa gggttacatg aagctcacca
      781 gctctatggc aggctgccct ggtcccaagt cctggccttc gcagcagctg tggcccaaga
      841 tggcttcaac gtgacccatg atctagctca tgccttggct gagcagctgc ctcccaatgc
      901 atctgaccgc ttcctggata ctttcctgcc actgggccac ccacccttgc ctggctccct
      961 gctgcgacgg cctgatctcg ctgaggtact ggatatactc ggcacctctg gccctgctgc
     1021 cttctacaat ggtggcaacc tcacactgga gatggtggct gaggctcagc acgcaggcgg
     1081 tgtcataacc gaggaggact tcagcaacta tagtgctctc acggagaagc ctgtgtgtgg
     1141 agtgtaccga ggccacctgg ttctcagccc cccaccccca cacacaggcc cggccctcat
     1201 cagtgctctc aacatcctgg agggcttcaa cctcaccagc ctggtgtccc gtgagcaagc
     1261 gcttcactgg gtagcagaga ccctgaagat tgcattggcc ctggctagca gactgggaga
     1321 ccctgtctat gattctacca tcactgagag catggacgac atgctcagca aggtggaggc
     1381 cgccaacttc cggggccaca tcagtgactc tcaggcagcc cctgccccac tcctgcctgt
     1441 ctatgagctg gacggggctc ccactgctgc ccaggtgctg gtcatgggcc ctgatgactt
     1501 catcgtagcc atggtcagct ccctgaaccg gccttttgga agtggcctcc tcactccctc
     1561 cgggatcctt ctcaacagcc agatgctaga cttctcctgg cccaacagga cagccaacca
     1621 ctctgcaccc agcctggaga actcggtaca gccagggaag cggcccctct ctttccttct
     1681 gcccactgta gtccgaccag cagaagggct ctgtgggacc tacctcgctc tgggggccaa
     1741 tggagctgct cgaggcctca gtggcctgac ccaggttcta ctgaatgtcc tgaccttgaa
     1801 caggaacctg agtgacagcc tggcccgagg acgcctccac ccagacctgc agtccaacct
     1861 cctgcaggtt gacagtgagt tcactgagga agagattgag ttcctggaag ccaggggtca
     1921 ccacgtggag aaggtagatg tcttatcctg ggtccacggc agtcggagaa ccaacacctt
     1981 catcatcggt gtgaaggacc ctcggagccc ggatgcagct ggagccacca tcctgtagag
     2041 cattgggctg ggcgggatct ctgctccccg cctttgcatg ttcccagagt ccctctttct
     2101 cccaggtttg gtctcagggg gaccccatgg atgcctcaga ttaggggcca aaggggatgc
     2161 ttagcaaacc ctatcccaga gtaactggaa aattctccaa ctggaggcct ttggtgggaa
     2221 tgatgacatc agtgtccatg accaggcagg caggaccttg aggagtcaga ttgtctgtct
     2281 cctctcctct ttcagccatg ctatccttga gcttagggat gtgcttgcaa acccttctca
     2341 agggtctcac tatcccaaca ccttcagact ggtctgacct aggccttgtc ttccagctcc
     2401 cttttcctgt atctggcccc atttcttaag tgactaggat tttttaaaaa attggccatt
     2461 atggggagag gtaatcctcg ccttccacca ggttgaggca ggggccttgc atttgaaggt
     2521 ccccaggcag ccacacaggg gtggggtggg tatcagctca ggggcttcca tttgcaatgg
     2581 ggaattaaag aaagaatatt gcttaaccct g
//
