LOCUS       NM_001382234            2299 bp    mRNA    linear   ROD 04-AUG-2024
DEFINITION  Mus musculus predicted gene, 52429 (Gcna), mRNA.
ACCESSION   NM_001382234 XM_030251537
VERSION     NM_001382234.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2299)
  AUTHORS   Ribeiro,J. and Crossan,G.P.
  TITLE     GCNA is a histone binding protein required for spermatogonial stem
            cell maintenance
  JOURNAL   Nucleic Acids Res 51 (10), 4791-4813 (2023)
   PUBMED   36919611
  REMARK    GeneRIF: GCNA is a histone binding protein required for
            spermatogonial stem cell maintenance.
REFERENCE   2  (bases 1 to 2299)
  AUTHORS   Nicol,B., Rodriguez,K. and Yao,H.H.
  TITLE     Aberrant and constitutive expression of FOXL2 impairs ovarian
            development and functions in mice
  JOURNAL   Biol Reprod 103 (5), 966-977 (2020)
   PUBMED   32945847
REFERENCE   3  (bases 1 to 2299)
  AUTHORS   Eozenou,C., Gonen,N., Touzon,M.S., Jorgensen,A., Yatsenko,S.A.,
            Fusee,L., Kamel,A.K., Gellen,B., Guercio,G., Singh,P., Witchel,S.,
            Berman,A.J., Mainpal,R., Totonchi,M., Mohseni Meybodi,A.,
            Askari,M., Merel-Chali,T., Bignon-Topalovic,J., Migale,R.,
            Costanzo,M., Marino,R., Ramirez,P., Perez Garrido,N.,
            Berensztein,E., Mekkawy,M.K., Schimenti,J.C., Bertalan,R.,
            Mazen,I., McElreavey,K., Belgorosky,A., Lovell-Badge,R.,
            Rajkovic,A. and Bashamboo,A.
  TITLE     Testis formation in XX individuals resulting from novel pathogenic
            variants in Wilms' tumor 1 (WT1) gene
  JOURNAL   Proc Natl Acad Sci U S A 117 (24), 13680-13688 (2020)
   PUBMED   32493750
REFERENCE   4  (bases 1 to 2299)
  AUTHORS   Kothandapani,A., Lewis,S.R., Noel,J.L., Zacharski,A., Krellwitz,K.,
            Baines,A., Winske,S., Vezina,C.M., Kaftanovskaya,E.M.,
            Agoulnik,A.I., Merton,E.M., Cohn,M.J. and Jorgensen,J.S.
  TITLE     GLI3 resides at the intersection of hedgehog and androgen action to
            promote male sex differentiation
  JOURNAL   PLoS Genet 16 (6), e1008810 (2020)
   PUBMED   32497091
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2299)
  AUTHORS   Chassot,A.A., Le Rolle,M., Jolivet,G., Stevant,I., Guigonis,J.M.,
            Da Silva,F., Nef,S., Pailhoux,E., Schedl,A., Ghyselinck,N.B. and
            Chaboissier,M.C.
  TITLE     Retinoic acid synthesis by ALDH1A proteins is dispensable for
            meiosis initiation in the mouse fetal ovary
  JOURNAL   Sci Adv 6 (21), eaaz1261 (2020)
   PUBMED   32494737
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2299)
  AUTHORS   Pepling,M.E. and Spradling,A.C.
  TITLE     Female mouse germ cells form synchronously dividing cysts
  JOURNAL   Development 125 (17), 3323-3328 (1998)
   PUBMED   9693136
REFERENCE   7  (bases 1 to 2299)
  AUTHORS   Wang,D., Ikeda,Y., Parker,K.L. and Enders,G.C.
  TITLE     Germ cell nuclear antigen (GCNA1) expression does not require a
            gonadal environment or steroidogenic factor 1: examination of GCNA1
            in ectopic germ cells and in Ftz-F1 null mice
  JOURNAL   Mol Reprod Dev 48 (2), 154-158 (1997)
   PUBMED   9291464
REFERENCE   8  (bases 1 to 2299)
  AUTHORS   Wang,D. and Enders,G.C.
  TITLE     Expression of a specific mouse germ cell nuclear antigen (GCNA1) by
            early embryonic testicular teratoma cells in 129/Sv-Sl/+ mice
  JOURNAL   Cancer Lett 100 (1-2), 31-36 (1996)
   PUBMED   8620450
REFERENCE   9  (bases 1 to 2299)
  AUTHORS   Enders,G.C. and May,J.J. 2nd.
  TITLE     Developmentally regulated expression of a mouse germ cell nuclear
            antigen examined from embryonic day 11 to adult in male and female
            mice
  JOURNAL   Dev Biol 163 (2), 331-340 (1994)
   PUBMED   8200475
REFERENCE   10 (bases 1 to 2299)
  AUTHORS   Mathies,H. and Wolff,E.
  TITLE     [The prednisolone saving effect of proquazone]
  JOURNAL   MMW Munch Med Wochenschr 121 (13), 459-460 (1979)
   PUBMED   107425
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            KX981576.1 and AL805980.28.
            
            On Apr 23, 2020 this sequence version replaced XM_030251537.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: KX981576.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2102              KX981576.1         86-2187
            2103-2299           AL805980.28        33513-33709
FEATURES             Location/Qualifiers
     source          1..2299
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X"
     gene            1..2299
                     /gene="Gcna"
                     /gene_synonym="Gcna1; Gm52429"
                     /note="predicted gene, 52429"
                     /db_xref="GeneID:115489118"
                     /db_xref="MGI:MGI:6366636"
     exon            1..88
                     /gene="Gcna"
                     /gene_synonym="Gcna1; Gm52429"
                     /inference="alignment:Splign:2.1.0"
     exon            89..261
                     /gene="Gcna"
                     /gene_synonym="Gcna1; Gm52429"
                     /inference="alignment:Splign:2.1.0"
     CDS             102..1625
                     /gene="Gcna"
                     /gene_synonym="Gcna1; Gm52429"
                     /note="germ cell nuclear antigen 1; acidic
                     repeat-containing protein"
                     /codon_start=1
                     /product="germ cell nuclear acidic protein"
                     /protein_id="NP_001369163.1"
                     /db_xref="GeneID:115489118"
                     /db_xref="MGI:MGI:6366636"
                     /translation="MDSGSSSSSSSSGSSSGSCSTSGSGSTSGSSTTSSSSSSSSSSS
                     SSSSSSSKEYMPELPKQRKASCVVIDSESDSDNTSDEKNTTVCEISSGDETSDIDRPG
                     GQKLPLIVIDDDDDGSPDLKNTKQKSDEPQMSVLEKEGVECIGSDSTSPHDVCEIWDV
                     CGSSNQTSSELEPEGEPESEAKGEPESEAKGEPESEAKGEPESEAKGESESEAKGEME
                     TEAKGESESEAKGEMETEAKGESESEAKGEMETEAKGEPESEAKGEMETEAKGEPESE
                     AKGEMETEAKGESESEAKGEMETEAKGESESEAKGEMETEAKGEPESEAKGEMETEAK
                     GEPESEAKGEPEPEAAKGEMETEAAMGEVETEAAMGEPEQEITAEEAKKKRAAYLLAQ
                     QRKRKRKNRFICMSSSKPRRKRRRADPQDGADPQDGADPQDRADPQDLADPQDRGDSQ
                     DMPSLPGTSDEPIPSGQPVCPRKGMASSRGRGRGRGRGRGRGRGRGRGRGRGAKAGK"
     exon            262..295
                     /gene="Gcna"
                     /gene_synonym="Gcna1; Gm52429"
                     /inference="alignment:Splign:2.1.0"
     exon            296..378
                     /gene="Gcna"
                     /gene_synonym="Gcna1; Gm52429"
                     /inference="alignment:Splign:2.1.0"
     exon            379..2299
                     /gene="Gcna"
                     /gene_synonym="Gcna1; Gm52429"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2270..2275
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gcna"
                     /gene_synonym="Gcna1; Gm52429"
                     /note="hexamer: AATAAA"
     polyA_site      2299
                     /gene="Gcna"
                     /gene_synonym="Gcna1; Gm52429"
                     /note="major polyA site"
ORIGIN      
        1 agaccgctcg gggagccgtt ggcggttgag accttctgcc aggccagatc agaccggacc
       61 agacgcggac ccggacacgg gagaacagtt attttctgaa catggattca ggcagcagca
      121 gcagcagcag tagcagtggc agcagcagtg gcagctgcag caccagtggc agtggcagca
      181 ccagtggcag cagcaccacc agcagcagca gcagcagcag cagcagcagc agcagcagca
      241 gcagcagcag cagtaaagaa tacatgcctg aactgccaaa acagagaaag gctagctgtg
      301 tcgtgattga ctccgaatcc gactccgaca ataccagtga cgaaaagaac actacagtct
      361 gtgaaataag cagtggagat gagacttctg acattgatcg tcccggaggt cagaagcttc
      421 cactaattgt tattgatgat gatgatgatg gcagccctga tttgaagaat actaagcaga
      481 aaagtgatga gccccaaatg tcggtgcttg aaaaagaggg ggttgaatgt attggttctg
      541 actcgacttc acctcatgat gtttgtgaaa tatgggatgt ttgtgggagt tccaaccaga
      601 catcaagtga gcttgagcca gagggggagc ctgaatcaga ggccaagggg gagcctgaat
      661 cagaggccaa gggggagccc gaatctgagg ccaaggggga gcccgaatct gaggccaagg
      721 gggagtccga atctgaagcc aagggggaga tggagactga ggccaagggg gagtccgaat
      781 ctgaagccaa gggggagatg gagactgagg ccaaggggga gtccgaatct gaagccaagg
      841 gggagatgga gactgaggcc aagggggagc ccgaatctga agccaagggg gagatggaga
      901 ctgaggccaa gggggagccc gaatctgaag ccaaggggga gatggagact gaggccaagg
      961 gggagtccga atctgaagcc aagggggaga tggagactga ggccaagggg gagtccgaat
     1021 ctgaagccaa gggggagatg gagactgagg ccaaggggga gcccgaatct gaagccaagg
     1081 gggagatgga gactgaggcc aagggggagc ccgaatctga agccaaaggg gagcccgagc
     1141 ccgaggctgc taagggggag atggagactg aggctgctat gggggaggtg gagactgagg
     1201 ctgctatggg ggagcccgag caagaaatta cagctgagga agccaaaaag aaaagggctg
     1261 catatctgct ggcacaacaa aggaaaagaa agagaaagaa cagattcata tgtatgtcat
     1321 caagtaagcc tcgtaggaaa cgccgtaggg ctgacccaca ggatggggct gacccacagg
     1381 atggggctga cccacaggat cgggctgacc cacaggatct ggctgaccca caggataggg
     1441 gtgactcaca ggatatgccc agcctgccag gtacatctga tgagcccatt ccatcgggcc
     1501 agcctgtttg tccccgaaaa ggcatggctt caagtagagg aaggggcagg ggcagaggca
     1561 gaggcagagg cagaggcaga ggcagaggca gaggcagagg cagaggggca aaggcaggaa
     1621 agtgaaaagg gcctttttgc aaattgccac tggttaggga gcgccactgt ccattttcct
     1681 tatgttccag tatatcagca ttccccaatg ttcaatcccc ctgcagtgtt tgtttctttt
     1741 tctttttctt tttctttttt cttttttctt ttttcttttt gttgagtcag ggtttctctg
     1801 tatagccctg gctgttctgg aactggctta taaagcaggc tagcctcaaa ctcatattca
     1861 cctacctttt cttcccaaga gctgggaata aagccgtgtg ccaccacgcc cggctttttt
     1921 tttttctttt tcttttttct cttttgttct tttgagacag ggtttctctg tatagccctg
     1981 gctgttctgg aactggctta taaagcaggc tggcctcaaa ttcatattca cctacctttt
     2041 cttcccaaga gctgggaata aagccgtgtg ccaccacgcc cggctttttt tttttttttt
     2101 tttcttttga gacagggttt ctctgtatag tcctggctgt tctggaactg gttctttaaa
     2161 gcaaactggc ctcaaactaa gaaaaccatc tacctctacc tcccaagggc tgggactaaa
     2221 ggtgtgtacc accaccgcct ggcataacaa atgtttgata aacttgttaa ataaatggcg
     2281 cttaactgtt ggttccaaa
//
